• Calling on LLMs: New NVIDIA AI Blueprint Helps Automate Telco Network Configuration

    Telecom companies last year spent nearly billion in capital expenditures and over trillion in operating expenditures.
    These large expenses are due in part to laborious manual processes that telcos face when operating networks that require continuous optimizations.
    For example, telcos must constantly tune network parameters for tasks — such as transferring calls from one network to another or distributing network traffic across multiple servers — based on the time of day, user behavior, mobility and traffic type.
    These factors directly affect network performance, user experience and energy consumption.
    To automate these optimization processes and save costs for telcos across the globe, NVIDIA today unveiled at GTC Paris its first AI Blueprint for telco network configuration.
    At the blueprint’s core are customized large language models trained specifically on telco network data — as well as the full technical and operational architecture for turning the LLMs into an autonomous, goal-driven AI agent for telcos.
    Automate Network Configuration With the AI Blueprint
    NVIDIA AI Blueprints — available on build.nvidia.com — are customizable AI workflow examples. They include reference code, documentation and deployment tools that show enterprise developers how to deliver business value with NVIDIA NIM microservices.
    The AI Blueprint for telco network configuration — built with BubbleRAN 5G solutions and datasets — enables developers, network engineers and telecom providers to automatically optimize the configuration of network parameters using agentic AI.
    This can streamline operations, reduce costs and significantly improve service quality by embedding continuous learning and adaptability directly into network infrastructures.
    Traditionally, network configurations required manual intervention or followed rigid rules to adapt to dynamic network conditions. These approaches limited adaptability and increased operational complexities, costs and inefficiencies.
    The new blueprint helps shift telco operations from relying on static, rules-based systems to operations based on dynamic, AI-driven automation. It enables developers to build advanced, telco-specific AI agents that make real-time, intelligent decisions and autonomously balance trade-offs — such as network speed versus interference, or energy savings versus utilization — without human input.
    Powered and Deployed by Industry Leaders
    Trained on 5G data generated by BubbleRAN, and deployed on the BubbleRAN 5G O-RAN platform, the blueprint provides telcos with insight on how to set various parameters to reach performance goals, like achieving a certain bitrate while choosing an acceptable signal-to-noise ratio — a measure that impacts voice quality and thus user experience.
    With the new AI Blueprint, network engineers can confidently set initial parameter values and update them as demanded by continuous network changes.
    Norway-based Telenor Group, which serves over 200 million customers globally, is the first telco to integrate the AI Blueprint for telco network configuration as part of its initiative to deploy intelligent, autonomous networks that meet the performance and agility demands of 5G and beyond.
    “The blueprint is helping us address configuration challenges and enhance quality of service during network installation,” said Knut Fjellheim, chief technology innovation officer at Telenor Maritime. “Implementing it is part of our push toward network automation and follows the successful deployment of agentic AI for real-time network slicing in a private 5G maritime use case.”
    Industry Partners Deploy Other NVIDIA-Powered Autonomous Network Technologies
    The AI Blueprint for telco network configuration is just one of many announcements at NVIDIA GTC Paris showcasing how the telecom industry is using agentic AI to make autonomous networks a reality.
    Beyond the blueprint, leading telecom companies and solutions providers are tapping into NVIDIA accelerated computing, software and microservices to provide breakthrough innovations poised to vastly improve networks and communications services — accelerating the progress to autonomous networks and improving customer experiences.
    NTT DATA is powering its agentic platform for telcos with NVIDIA accelerated compute and the NVIDIA AI Enterprise software platform. Its first agentic use case is focused on network alarms management, where NVIDIA NIM microservices help automate and power observability, troubleshooting, anomaly detection and resolution with closed loop ticketing.
    Tata Consultancy Services is delivering agentic AI solutions for telcos built on NVIDIA DGX Cloud and using NVIDIA AI Enterprise to develop, fine-tune and integrate large telco models into AI agent workflows. These range from billing and revenue assurance, autonomous network management to hybrid edge-cloud distributed inference.
    For example, the company’s anomaly management agentic AI model includes real-time detection and resolution of network anomalies and service performance optimization. This increases business agility and improves operational efficiencies by up to 40% by eliminating human intensive toils, overheads and cross-departmental silos.
    Prodapt has introduced an autonomous operations workflow for networks, powered by NVIDIA AI Enterprise, that offers agentic AI capabilities to support autonomous telecom networks. AI agents can autonomously monitor networks, detect anomalies in real time, initiate diagnostics, analyze root causes of issues using historical data and correlation techniques, automatically execute corrective actions, and generate, enrich and assign incident tickets through integrated ticketing systems.
    Accenture announced its new portfolio of agentic AI solutions for telecommunications through its AI Refinery platform, built on NVIDIA AI Enterprise software and accelerated computing.
    The first available solution, the NOC Agentic App, boosts network operations center tasks by using a generative AI-driven, nonlinear agentic framework to automate processes such as incident and fault management, root cause analysis and configuration planning. Using the Llama 3.1 70B NVIDIA NIM microservice and the AI Refinery Distiller Framework, the NOC Agentic App orchestrates networks of intelligent agents for faster, more efficient decision-making.
    Infosys is announcing its agentic autonomous operations platform, called Infosys Smart Network Assurance, designed to accelerate telecom operators’ journeys toward fully autonomous network operations.
    ISNA helps address long-standing operational challenges for telcos — such as limited automation and high average time to repair — with an integrated, AI-driven platform that reduces operational costs by up to 40% and shortens fault resolution times by up to 30%. NVIDIA NIM and NeMo microservices enhance the platform’s reasoning and hallucination-detection capabilities, reduce latency and increase accuracy.
    Get started with the new blueprint today.
    Learn more about the latest AI advancements for telecom and other industries at NVIDIA GTC Paris, running through Thursday, June 12, at VivaTech, including a keynote from NVIDIA founder and CEO Jensen Huang and a special address from Ronnie Vasishta, senior vice president of telecom at NVIDIA. Plus, hear from industry leaders in a panel session with Orange, Swisscom, Telenor and NVIDIA.
    #calling #llms #new #nvidia #blueprint
    Calling on LLMs: New NVIDIA AI Blueprint Helps Automate Telco Network Configuration
    Telecom companies last year spent nearly billion in capital expenditures and over trillion in operating expenditures. These large expenses are due in part to laborious manual processes that telcos face when operating networks that require continuous optimizations. For example, telcos must constantly tune network parameters for tasks — such as transferring calls from one network to another or distributing network traffic across multiple servers — based on the time of day, user behavior, mobility and traffic type. These factors directly affect network performance, user experience and energy consumption. To automate these optimization processes and save costs for telcos across the globe, NVIDIA today unveiled at GTC Paris its first AI Blueprint for telco network configuration. At the blueprint’s core are customized large language models trained specifically on telco network data — as well as the full technical and operational architecture for turning the LLMs into an autonomous, goal-driven AI agent for telcos. Automate Network Configuration With the AI Blueprint NVIDIA AI Blueprints — available on build.nvidia.com — are customizable AI workflow examples. They include reference code, documentation and deployment tools that show enterprise developers how to deliver business value with NVIDIA NIM microservices. The AI Blueprint for telco network configuration — built with BubbleRAN 5G solutions and datasets — enables developers, network engineers and telecom providers to automatically optimize the configuration of network parameters using agentic AI. This can streamline operations, reduce costs and significantly improve service quality by embedding continuous learning and adaptability directly into network infrastructures. Traditionally, network configurations required manual intervention or followed rigid rules to adapt to dynamic network conditions. These approaches limited adaptability and increased operational complexities, costs and inefficiencies. The new blueprint helps shift telco operations from relying on static, rules-based systems to operations based on dynamic, AI-driven automation. It enables developers to build advanced, telco-specific AI agents that make real-time, intelligent decisions and autonomously balance trade-offs — such as network speed versus interference, or energy savings versus utilization — without human input. Powered and Deployed by Industry Leaders Trained on 5G data generated by BubbleRAN, and deployed on the BubbleRAN 5G O-RAN platform, the blueprint provides telcos with insight on how to set various parameters to reach performance goals, like achieving a certain bitrate while choosing an acceptable signal-to-noise ratio — a measure that impacts voice quality and thus user experience. With the new AI Blueprint, network engineers can confidently set initial parameter values and update them as demanded by continuous network changes. Norway-based Telenor Group, which serves over 200 million customers globally, is the first telco to integrate the AI Blueprint for telco network configuration as part of its initiative to deploy intelligent, autonomous networks that meet the performance and agility demands of 5G and beyond. “The blueprint is helping us address configuration challenges and enhance quality of service during network installation,” said Knut Fjellheim, chief technology innovation officer at Telenor Maritime. “Implementing it is part of our push toward network automation and follows the successful deployment of agentic AI for real-time network slicing in a private 5G maritime use case.” Industry Partners Deploy Other NVIDIA-Powered Autonomous Network Technologies The AI Blueprint for telco network configuration is just one of many announcements at NVIDIA GTC Paris showcasing how the telecom industry is using agentic AI to make autonomous networks a reality. Beyond the blueprint, leading telecom companies and solutions providers are tapping into NVIDIA accelerated computing, software and microservices to provide breakthrough innovations poised to vastly improve networks and communications services — accelerating the progress to autonomous networks and improving customer experiences. NTT DATA is powering its agentic platform for telcos with NVIDIA accelerated compute and the NVIDIA AI Enterprise software platform. Its first agentic use case is focused on network alarms management, where NVIDIA NIM microservices help automate and power observability, troubleshooting, anomaly detection and resolution with closed loop ticketing. Tata Consultancy Services is delivering agentic AI solutions for telcos built on NVIDIA DGX Cloud and using NVIDIA AI Enterprise to develop, fine-tune and integrate large telco models into AI agent workflows. These range from billing and revenue assurance, autonomous network management to hybrid edge-cloud distributed inference. For example, the company’s anomaly management agentic AI model includes real-time detection and resolution of network anomalies and service performance optimization. This increases business agility and improves operational efficiencies by up to 40% by eliminating human intensive toils, overheads and cross-departmental silos. Prodapt has introduced an autonomous operations workflow for networks, powered by NVIDIA AI Enterprise, that offers agentic AI capabilities to support autonomous telecom networks. AI agents can autonomously monitor networks, detect anomalies in real time, initiate diagnostics, analyze root causes of issues using historical data and correlation techniques, automatically execute corrective actions, and generate, enrich and assign incident tickets through integrated ticketing systems. Accenture announced its new portfolio of agentic AI solutions for telecommunications through its AI Refinery platform, built on NVIDIA AI Enterprise software and accelerated computing. The first available solution, the NOC Agentic App, boosts network operations center tasks by using a generative AI-driven, nonlinear agentic framework to automate processes such as incident and fault management, root cause analysis and configuration planning. Using the Llama 3.1 70B NVIDIA NIM microservice and the AI Refinery Distiller Framework, the NOC Agentic App orchestrates networks of intelligent agents for faster, more efficient decision-making. Infosys is announcing its agentic autonomous operations platform, called Infosys Smart Network Assurance, designed to accelerate telecom operators’ journeys toward fully autonomous network operations. ISNA helps address long-standing operational challenges for telcos — such as limited automation and high average time to repair — with an integrated, AI-driven platform that reduces operational costs by up to 40% and shortens fault resolution times by up to 30%. NVIDIA NIM and NeMo microservices enhance the platform’s reasoning and hallucination-detection capabilities, reduce latency and increase accuracy. Get started with the new blueprint today. Learn more about the latest AI advancements for telecom and other industries at NVIDIA GTC Paris, running through Thursday, June 12, at VivaTech, including a keynote from NVIDIA founder and CEO Jensen Huang and a special address from Ronnie Vasishta, senior vice president of telecom at NVIDIA. Plus, hear from industry leaders in a panel session with Orange, Swisscom, Telenor and NVIDIA. #calling #llms #new #nvidia #blueprint
    BLOGS.NVIDIA.COM
    Calling on LLMs: New NVIDIA AI Blueprint Helps Automate Telco Network Configuration
    Telecom companies last year spent nearly $295 billion in capital expenditures and over $1 trillion in operating expenditures. These large expenses are due in part to laborious manual processes that telcos face when operating networks that require continuous optimizations. For example, telcos must constantly tune network parameters for tasks — such as transferring calls from one network to another or distributing network traffic across multiple servers — based on the time of day, user behavior, mobility and traffic type. These factors directly affect network performance, user experience and energy consumption. To automate these optimization processes and save costs for telcos across the globe, NVIDIA today unveiled at GTC Paris its first AI Blueprint for telco network configuration. At the blueprint’s core are customized large language models trained specifically on telco network data — as well as the full technical and operational architecture for turning the LLMs into an autonomous, goal-driven AI agent for telcos. Automate Network Configuration With the AI Blueprint NVIDIA AI Blueprints — available on build.nvidia.com — are customizable AI workflow examples. They include reference code, documentation and deployment tools that show enterprise developers how to deliver business value with NVIDIA NIM microservices. The AI Blueprint for telco network configuration — built with BubbleRAN 5G solutions and datasets — enables developers, network engineers and telecom providers to automatically optimize the configuration of network parameters using agentic AI. This can streamline operations, reduce costs and significantly improve service quality by embedding continuous learning and adaptability directly into network infrastructures. Traditionally, network configurations required manual intervention or followed rigid rules to adapt to dynamic network conditions. These approaches limited adaptability and increased operational complexities, costs and inefficiencies. The new blueprint helps shift telco operations from relying on static, rules-based systems to operations based on dynamic, AI-driven automation. It enables developers to build advanced, telco-specific AI agents that make real-time, intelligent decisions and autonomously balance trade-offs — such as network speed versus interference, or energy savings versus utilization — without human input. Powered and Deployed by Industry Leaders Trained on 5G data generated by BubbleRAN, and deployed on the BubbleRAN 5G O-RAN platform, the blueprint provides telcos with insight on how to set various parameters to reach performance goals, like achieving a certain bitrate while choosing an acceptable signal-to-noise ratio — a measure that impacts voice quality and thus user experience. With the new AI Blueprint, network engineers can confidently set initial parameter values and update them as demanded by continuous network changes. Norway-based Telenor Group, which serves over 200 million customers globally, is the first telco to integrate the AI Blueprint for telco network configuration as part of its initiative to deploy intelligent, autonomous networks that meet the performance and agility demands of 5G and beyond. “The blueprint is helping us address configuration challenges and enhance quality of service during network installation,” said Knut Fjellheim, chief technology innovation officer at Telenor Maritime. “Implementing it is part of our push toward network automation and follows the successful deployment of agentic AI for real-time network slicing in a private 5G maritime use case.” Industry Partners Deploy Other NVIDIA-Powered Autonomous Network Technologies The AI Blueprint for telco network configuration is just one of many announcements at NVIDIA GTC Paris showcasing how the telecom industry is using agentic AI to make autonomous networks a reality. Beyond the blueprint, leading telecom companies and solutions providers are tapping into NVIDIA accelerated computing, software and microservices to provide breakthrough innovations poised to vastly improve networks and communications services — accelerating the progress to autonomous networks and improving customer experiences. NTT DATA is powering its agentic platform for telcos with NVIDIA accelerated compute and the NVIDIA AI Enterprise software platform. Its first agentic use case is focused on network alarms management, where NVIDIA NIM microservices help automate and power observability, troubleshooting, anomaly detection and resolution with closed loop ticketing. Tata Consultancy Services is delivering agentic AI solutions for telcos built on NVIDIA DGX Cloud and using NVIDIA AI Enterprise to develop, fine-tune and integrate large telco models into AI agent workflows. These range from billing and revenue assurance, autonomous network management to hybrid edge-cloud distributed inference. For example, the company’s anomaly management agentic AI model includes real-time detection and resolution of network anomalies and service performance optimization. This increases business agility and improves operational efficiencies by up to 40% by eliminating human intensive toils, overheads and cross-departmental silos. Prodapt has introduced an autonomous operations workflow for networks, powered by NVIDIA AI Enterprise, that offers agentic AI capabilities to support autonomous telecom networks. AI agents can autonomously monitor networks, detect anomalies in real time, initiate diagnostics, analyze root causes of issues using historical data and correlation techniques, automatically execute corrective actions, and generate, enrich and assign incident tickets through integrated ticketing systems. Accenture announced its new portfolio of agentic AI solutions for telecommunications through its AI Refinery platform, built on NVIDIA AI Enterprise software and accelerated computing. The first available solution, the NOC Agentic App, boosts network operations center tasks by using a generative AI-driven, nonlinear agentic framework to automate processes such as incident and fault management, root cause analysis and configuration planning. Using the Llama 3.1 70B NVIDIA NIM microservice and the AI Refinery Distiller Framework, the NOC Agentic App orchestrates networks of intelligent agents for faster, more efficient decision-making. Infosys is announcing its agentic autonomous operations platform, called Infosys Smart Network Assurance (ISNA), designed to accelerate telecom operators’ journeys toward fully autonomous network operations. ISNA helps address long-standing operational challenges for telcos — such as limited automation and high average time to repair — with an integrated, AI-driven platform that reduces operational costs by up to 40% and shortens fault resolution times by up to 30%. NVIDIA NIM and NeMo microservices enhance the platform’s reasoning and hallucination-detection capabilities, reduce latency and increase accuracy. Get started with the new blueprint today. Learn more about the latest AI advancements for telecom and other industries at NVIDIA GTC Paris, running through Thursday, June 12, at VivaTech, including a keynote from NVIDIA founder and CEO Jensen Huang and a special address from Ronnie Vasishta, senior vice president of telecom at NVIDIA. Plus, hear from industry leaders in a panel session with Orange, Swisscom, Telenor and NVIDIA.
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  • Monster Hunter Wilds’ second free title update brings fierce new monsters and more June 30

    New monsters, features, and more arrive in the Forbidden Lands with Free Title Update 2, dropping in Monster Hunter Wilds on June 30! Watch the latest trailer for a look at what awaits you.

    Play Video

    Monster Hunter Wilds – Free Title Update 2

    In addition to what’s featured in the trailer, Free Title Update 2 will also feature improvements and adjustments to various aspects of the game. Make sure to check the official Monster Hunter Wilds website for a new Director’s Letter from Game Director Yuya Tokuda coming soon, for a deeper dive into what’s coming in addition to the core new monsters and features.

    ● The Leviathan, Lagiacrus, emerges at last

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    The long-awaited Leviathan, Lagiacrus, has finally appeared in Monster Hunter Wilds! Floating at the top of the aquatic food chain, Lagiacrus is a master of the sea, boiling the surrounding water by emitting powerful currents of electricity. New missions to hunt Lagiacrus will become available for hunters at Hunter Rank 31 or above, and after clearing the “A World Turned Upside Down” main mission, and the “Forest Doshaguma” side mission.

    While you’ll fight Lagiacrus primarily on land, your hunt against this formidable foe can also take you deep underwater for a special encounter, where it feels most at home. During the underwater portion of the hunt, hunters won’t be able to use their weapons freely, but there are still ways to fight back and turn the tide of battle. Stay alert for your opportunities!

    Hunt Lagiacrus to obtain materials for new hunter and Palico armor! As usual, these sets can be used as layered armor as well.

    ● The Flying Wyvern, Seregios, strikes

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    Shining golden bright, the flying wyvern, Seregios, swoops into the Forbidden Lands with Free Title Update 2! Seregios is a highly mobile aerial monster that fires sharp bladescales, inflicting bleeding status on hunters. Keep an eye on your health and bring along rations and well-done steak when hunting this monster. Missions to hunt Seregios are available for hunters at HR 31 or above that have cleared the “A World Turned Upside Down” main mission.

    New hunter and Palico armor forged from Seregios materials awaits you!

    For hunters looking for a greater challenge, 8★ Tempered Lagiacrus and Seregios will begin appearing for hunters at HR 41 or higher, after completing their initial missions. Best of luck against these powerful monsters!

    Hunt in style with layered weapons

    With Free Title Update 2, hunters will be able to use Layered Weapons, which lets you use the look of any weapon, while keeping the stats and abilities of another.

    To unlock a weapon design as a Layered Weapon option, you’ll need to craft the final weapon in that weapon’s upgrade tree. Artian Weapons can be used as layered weapons by fully reinforcing a Rarity 8 Artian weapon.

    For weapons that change in appearance when upgraded, you’ll also have the option to use their pre-upgrade designs as well! You can also craft layered Palico weapons by forging their high-rank weapons. We hope this feature encourages you to delve deeper into crafting the powerful Artian Weapon you’ve been looking for, all while keeping the appearance of your favorite weapon.

    New optional features

    Change your choice of handler accompanying you in the field to Eric after completing the Lagiacrus mission in Free Title Update 2! You can always switch back to Alma too, but it doesn’t hurt to give our trusty handler a break from time to time.

    A new Support Hunter joins the fray

    Mina, a support hunter who wields a Sword & Shield, joins the hunt. With Free Title Update 2, you’ll be able to choose which support hunters can join you on quests.

    Photo Mode Improvements

    Snap even more creative photos of your hunts with some new options, including an Effects tab to adjust brightness and filter effects, and a Character Display tab to toggle off your Handler, Palico, Seikret, and more.

    Celebrate summer with the Festival of Accord: Flamefete seasonal event

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    The next seasonal event in Monster Hunter Wilds, the Festival of Accord: Flamefete, will take place in the Grand Hub from July 23 to August 6! Cool off with this summer themed celebration, where you can obtain new armor, gestures, and pop-up camp decorations for a limited time. You’ll also be able to eat special seasonal event meals and enjoy the fun of summer as the Grand Hub and all it’s members will be dressed to mark the occasion.

    Arch-Tempered Uth Duna slams down starting July 30

    Take on an even more powerful version of Uth Duna when Arch-Tempered Uth Duna arrives as an Event Quest and Free Challenge Quest from July 30 to August 20! Take on and defeat the challenging apex of the Scarlet Forest to obtain materials for crafting the new Uth Duna γ hunter armor set and the Felyne Uth Duna γ Palico armor set. Be sure you’re at least HR 50 or above to take on this quest.

    We’ve also got plenty of new Event Quests on the way in the weeks ahead, including some where you can earn new special equipment, quests to obtain more armor spheres, and challenge quests against Mizutsune. Be sure to keep checking back each week to see what’s new!

    A special collaboration with Fender

    Monster Hunter Wilds is collaborating with world-renowned guitar brand Fender®! From August 27 to September 24, a special Event Quest will be available to earn a collaboration gesture that lets you rock out with the Monster Hunter Rathalos Telecaster®.

    In celebration of Monster Hunter’s 20th anniversary, the globally released Monster Hunter Rathalos Telecaster® collaboration guitar is making its way into the game! Be sure to experience it both in-game and in real life!

    A new round of cosmetic DLC arrives

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    Express your style with additional DLC, including four free dance gestures. Paid cosmetic DLC, such as gestures, stickers, pendants, and more will also be available. If you’ve purchased the Premium Deluxe Edition of Monster Hunter Wilds or the Cosmetic DLC Pass, Cosmetic DLC Pack 2 and other additional items will be available to download when Free Title Update 2 releases. 

    Free Title Update roadmap

    We hope you’re excited to dive into all the content coming with Free Title Update 2! We’ll continue to release updates, with Free Title Update 3 coming at the end of September. Stay tuned for more details to come.

    A Monster Hunter Wilds background is added to the PS5 Welcome hub

    Alongside Free Title Update 2 on June 30, an animated background featuring the hunters facing Arkveld during the Inclemency will be added to the Welcome hub. Customize your PS5 Welcome hub with Monster Hunter Wilds to get you in the hunting mood.

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    How to change the backgroundWelcome hub -> Change background -> Games

    Try out Monster Hunter Wilds on PS5 with a PlayStation Plus Premium Game Trial starting on June 30

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    With the Game Trial, you can try out the full version of the game for 2 hours. If you decide to purchase the full version after the trial, your save data will carry over, allowing you to continue playing seamlessly right where you left off. If you haven’t played Monster Hunter Wilds yet, this is a great way to give it a try.

    Happy Hunting!
    #monster #hunter #wilds #second #free
    Monster Hunter Wilds’ second free title update brings fierce new monsters and more June 30
    New monsters, features, and more arrive in the Forbidden Lands with Free Title Update 2, dropping in Monster Hunter Wilds on June 30! Watch the latest trailer for a look at what awaits you. Play Video Monster Hunter Wilds – Free Title Update 2 In addition to what’s featured in the trailer, Free Title Update 2 will also feature improvements and adjustments to various aspects of the game. Make sure to check the official Monster Hunter Wilds website for a new Director’s Letter from Game Director Yuya Tokuda coming soon, for a deeper dive into what’s coming in addition to the core new monsters and features. ● The Leviathan, Lagiacrus, emerges at last View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image The long-awaited Leviathan, Lagiacrus, has finally appeared in Monster Hunter Wilds! Floating at the top of the aquatic food chain, Lagiacrus is a master of the sea, boiling the surrounding water by emitting powerful currents of electricity. New missions to hunt Lagiacrus will become available for hunters at Hunter Rank 31 or above, and after clearing the “A World Turned Upside Down” main mission, and the “Forest Doshaguma” side mission. While you’ll fight Lagiacrus primarily on land, your hunt against this formidable foe can also take you deep underwater for a special encounter, where it feels most at home. During the underwater portion of the hunt, hunters won’t be able to use their weapons freely, but there are still ways to fight back and turn the tide of battle. Stay alert for your opportunities! Hunt Lagiacrus to obtain materials for new hunter and Palico armor! As usual, these sets can be used as layered armor as well. ● The Flying Wyvern, Seregios, strikes View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image Shining golden bright, the flying wyvern, Seregios, swoops into the Forbidden Lands with Free Title Update 2! Seregios is a highly mobile aerial monster that fires sharp bladescales, inflicting bleeding status on hunters. Keep an eye on your health and bring along rations and well-done steak when hunting this monster. Missions to hunt Seregios are available for hunters at HR 31 or above that have cleared the “A World Turned Upside Down” main mission. New hunter and Palico armor forged from Seregios materials awaits you! For hunters looking for a greater challenge, 8★ Tempered Lagiacrus and Seregios will begin appearing for hunters at HR 41 or higher, after completing their initial missions. Best of luck against these powerful monsters! Hunt in style with layered weapons With Free Title Update 2, hunters will be able to use Layered Weapons, which lets you use the look of any weapon, while keeping the stats and abilities of another. To unlock a weapon design as a Layered Weapon option, you’ll need to craft the final weapon in that weapon’s upgrade tree. Artian Weapons can be used as layered weapons by fully reinforcing a Rarity 8 Artian weapon. For weapons that change in appearance when upgraded, you’ll also have the option to use their pre-upgrade designs as well! You can also craft layered Palico weapons by forging their high-rank weapons. We hope this feature encourages you to delve deeper into crafting the powerful Artian Weapon you’ve been looking for, all while keeping the appearance of your favorite weapon. New optional features Change your choice of handler accompanying you in the field to Eric after completing the Lagiacrus mission in Free Title Update 2! You can always switch back to Alma too, but it doesn’t hurt to give our trusty handler a break from time to time. A new Support Hunter joins the fray Mina, a support hunter who wields a Sword & Shield, joins the hunt. With Free Title Update 2, you’ll be able to choose which support hunters can join you on quests. Photo Mode Improvements Snap even more creative photos of your hunts with some new options, including an Effects tab to adjust brightness and filter effects, and a Character Display tab to toggle off your Handler, Palico, Seikret, and more. Celebrate summer with the Festival of Accord: Flamefete seasonal event View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image The next seasonal event in Monster Hunter Wilds, the Festival of Accord: Flamefete, will take place in the Grand Hub from July 23 to August 6! Cool off with this summer themed celebration, where you can obtain new armor, gestures, and pop-up camp decorations for a limited time. You’ll also be able to eat special seasonal event meals and enjoy the fun of summer as the Grand Hub and all it’s members will be dressed to mark the occasion. Arch-Tempered Uth Duna slams down starting July 30 Take on an even more powerful version of Uth Duna when Arch-Tempered Uth Duna arrives as an Event Quest and Free Challenge Quest from July 30 to August 20! Take on and defeat the challenging apex of the Scarlet Forest to obtain materials for crafting the new Uth Duna γ hunter armor set and the Felyne Uth Duna γ Palico armor set. Be sure you’re at least HR 50 or above to take on this quest. We’ve also got plenty of new Event Quests on the way in the weeks ahead, including some where you can earn new special equipment, quests to obtain more armor spheres, and challenge quests against Mizutsune. Be sure to keep checking back each week to see what’s new! A special collaboration with Fender Monster Hunter Wilds is collaborating with world-renowned guitar brand Fender®! From August 27 to September 24, a special Event Quest will be available to earn a collaboration gesture that lets you rock out with the Monster Hunter Rathalos Telecaster®. In celebration of Monster Hunter’s 20th anniversary, the globally released Monster Hunter Rathalos Telecaster® collaboration guitar is making its way into the game! Be sure to experience it both in-game and in real life! A new round of cosmetic DLC arrives View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image Express your style with additional DLC, including four free dance gestures. Paid cosmetic DLC, such as gestures, stickers, pendants, and more will also be available. If you’ve purchased the Premium Deluxe Edition of Monster Hunter Wilds or the Cosmetic DLC Pass, Cosmetic DLC Pack 2 and other additional items will be available to download when Free Title Update 2 releases.  Free Title Update roadmap We hope you’re excited to dive into all the content coming with Free Title Update 2! We’ll continue to release updates, with Free Title Update 3 coming at the end of September. Stay tuned for more details to come. A Monster Hunter Wilds background is added to the PS5 Welcome hub Alongside Free Title Update 2 on June 30, an animated background featuring the hunters facing Arkveld during the Inclemency will be added to the Welcome hub. Customize your PS5 Welcome hub with Monster Hunter Wilds to get you in the hunting mood. View and download image Download the image close Close Download this image How to change the backgroundWelcome hub -> Change background -> Games Try out Monster Hunter Wilds on PS5 with a PlayStation Plus Premium Game Trial starting on June 30 View and download image Download the image close Close Download this image With the Game Trial, you can try out the full version of the game for 2 hours. If you decide to purchase the full version after the trial, your save data will carry over, allowing you to continue playing seamlessly right where you left off. If you haven’t played Monster Hunter Wilds yet, this is a great way to give it a try. Happy Hunting! #monster #hunter #wilds #second #free
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    Monster Hunter Wilds’ second free title update brings fierce new monsters and more June 30
    New monsters, features, and more arrive in the Forbidden Lands with Free Title Update 2, dropping in Monster Hunter Wilds on June 30! Watch the latest trailer for a look at what awaits you. Play Video Monster Hunter Wilds – Free Title Update 2 In addition to what’s featured in the trailer, Free Title Update 2 will also feature improvements and adjustments to various aspects of the game. Make sure to check the official Monster Hunter Wilds website for a new Director’s Letter from Game Director Yuya Tokuda coming soon, for a deeper dive into what’s coming in addition to the core new monsters and features. ● The Leviathan, Lagiacrus, emerges at last View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image The long-awaited Leviathan, Lagiacrus, has finally appeared in Monster Hunter Wilds! Floating at the top of the aquatic food chain, Lagiacrus is a master of the sea, boiling the surrounding water by emitting powerful currents of electricity. New missions to hunt Lagiacrus will become available for hunters at Hunter Rank 31 or above, and after clearing the “A World Turned Upside Down” main mission, and the “Forest Doshaguma” side mission. While you’ll fight Lagiacrus primarily on land, your hunt against this formidable foe can also take you deep underwater for a special encounter, where it feels most at home. During the underwater portion of the hunt, hunters won’t be able to use their weapons freely, but there are still ways to fight back and turn the tide of battle. Stay alert for your opportunities! Hunt Lagiacrus to obtain materials for new hunter and Palico armor! As usual, these sets can be used as layered armor as well. ● The Flying Wyvern, Seregios, strikes View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image Shining golden bright, the flying wyvern, Seregios, swoops into the Forbidden Lands with Free Title Update 2! Seregios is a highly mobile aerial monster that fires sharp bladescales, inflicting bleeding status on hunters. Keep an eye on your health and bring along rations and well-done steak when hunting this monster. Missions to hunt Seregios are available for hunters at HR 31 or above that have cleared the “A World Turned Upside Down” main mission. New hunter and Palico armor forged from Seregios materials awaits you! For hunters looking for a greater challenge, 8★ Tempered Lagiacrus and Seregios will begin appearing for hunters at HR 41 or higher, after completing their initial missions. Best of luck against these powerful monsters! Hunt in style with layered weapons With Free Title Update 2, hunters will be able to use Layered Weapons, which lets you use the look of any weapon, while keeping the stats and abilities of another. To unlock a weapon design as a Layered Weapon option, you’ll need to craft the final weapon in that weapon’s upgrade tree. Artian Weapons can be used as layered weapons by fully reinforcing a Rarity 8 Artian weapon. For weapons that change in appearance when upgraded, you’ll also have the option to use their pre-upgrade designs as well! You can also craft layered Palico weapons by forging their high-rank weapons. We hope this feature encourages you to delve deeper into crafting the powerful Artian Weapon you’ve been looking for, all while keeping the appearance of your favorite weapon. New optional features Change your choice of handler accompanying you in the field to Eric after completing the Lagiacrus mission in Free Title Update 2! You can always switch back to Alma too, but it doesn’t hurt to give our trusty handler a break from time to time. A new Support Hunter joins the fray Mina, a support hunter who wields a Sword & Shield, joins the hunt. With Free Title Update 2, you’ll be able to choose which support hunters can join you on quests. Photo Mode Improvements Snap even more creative photos of your hunts with some new options, including an Effects tab to adjust brightness and filter effects, and a Character Display tab to toggle off your Handler, Palico, Seikret, and more. Celebrate summer with the Festival of Accord: Flamefete seasonal event View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image The next seasonal event in Monster Hunter Wilds, the Festival of Accord: Flamefete, will take place in the Grand Hub from July 23 to August 6! Cool off with this summer themed celebration, where you can obtain new armor, gestures, and pop-up camp decorations for a limited time. You’ll also be able to eat special seasonal event meals and enjoy the fun of summer as the Grand Hub and all it’s members will be dressed to mark the occasion. Arch-Tempered Uth Duna slams down starting July 30 Take on an even more powerful version of Uth Duna when Arch-Tempered Uth Duna arrives as an Event Quest and Free Challenge Quest from July 30 to August 20! Take on and defeat the challenging apex of the Scarlet Forest to obtain materials for crafting the new Uth Duna γ hunter armor set and the Felyne Uth Duna γ Palico armor set. Be sure you’re at least HR 50 or above to take on this quest. We’ve also got plenty of new Event Quests on the way in the weeks ahead, including some where you can earn new special equipment, quests to obtain more armor spheres, and challenge quests against Mizutsune. Be sure to keep checking back each week to see what’s new! A special collaboration with Fender Monster Hunter Wilds is collaborating with world-renowned guitar brand Fender®! From August 27 to September 24, a special Event Quest will be available to earn a collaboration gesture that lets you rock out with the Monster Hunter Rathalos Telecaster®. In celebration of Monster Hunter’s 20th anniversary, the globally released Monster Hunter Rathalos Telecaster® collaboration guitar is making its way into the game! Be sure to experience it both in-game and in real life! A new round of cosmetic DLC arrives View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image View and download image Download the image close Close Download this image Express your style with additional DLC, including four free dance gestures. Paid cosmetic DLC, such as gestures, stickers, pendants, and more will also be available. If you’ve purchased the Premium Deluxe Edition of Monster Hunter Wilds or the Cosmetic DLC Pass, Cosmetic DLC Pack 2 and other additional items will be available to download when Free Title Update 2 releases.  Free Title Update roadmap We hope you’re excited to dive into all the content coming with Free Title Update 2! We’ll continue to release updates, with Free Title Update 3 coming at the end of September. Stay tuned for more details to come. A Monster Hunter Wilds background is added to the PS5 Welcome hub Alongside Free Title Update 2 on June 30, an animated background featuring the hunters facing Arkveld during the Inclemency will be added to the Welcome hub. Customize your PS5 Welcome hub with Monster Hunter Wilds to get you in the hunting mood. View and download image Download the image close Close Download this image How to change the backgroundWelcome hub -> Change background -> Games Try out Monster Hunter Wilds on PS5 with a PlayStation Plus Premium Game Trial starting on June 30 View and download image Download the image close Close Download this image With the Game Trial, you can try out the full version of the game for 2 hours. If you decide to purchase the full version after the trial, your save data will carry over, allowing you to continue playing seamlessly right where you left off. If you haven’t played Monster Hunter Wilds yet, this is a great way to give it a try. Happy Hunting!
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  • Ansys: R&D Engineer II (Remote - East Coast, US)

    Requisition #: 16890 Our Mission: Powering Innovation That Drives Human Advancement When visionary companies need to know how their world-changing ideas will perform, they close the gap between design and reality with Ansys simulation. For more than 50 years, Ansys software has enabled innovators across industries to push boundaries by using the predictive power of simulation. From sustainable transportation to advanced semiconductors, from satellite systems to life-saving medical devices, the next great leaps in human advancement will be powered by Ansys. Innovate With Ansys, Power Your Career. Summary / Role Purpose The R&D Engineer II contributes to the development of software products and supporting systems. In this role, the R&D Engineer II will collaborate with a team of expert professionals to understand customer requirements and accomplish development objectives. Key Duties and Responsibilities Performs moderately complex development activities, including the design, implementation, maintenance, testing and documentation of software modules and sub-systems Understands and employs best practices Performs moderately complex bug verification, release testing and beta support for assigned products. Researches problems discovered by QA or product support and develops solutions Understands the marketing requirements for a product, including target environment, performance criteria and competitive issues Works under the general supervision of a development manager Minimum Education/Certification Requirements and Experience BS in Computer Science, Applied Mathematics, Engineering, or other natural science disciplines with 3-5 years' experience or MS with minimum 2 years experience Working experience within technical software development proven by academic, research, or industry projects. Good understanding and skills in object-oriented programming Experience with Java and C# / .NET Role can be remote, must be based on the East Coast due to timezone Preferred Qualifications and Skills Experience with C++, Python, in addition to Java and C# / .NET Knowledge of Task-Based Asynchronous design patternExposure to model-based systems engineering concepts Working knowledge of SysML Know-how on cloud computing technologies like micro-service architectures, RPC frameworks, REST APIs, etc. Knowledge of software security best practices Experience working on an Agile software development team Technical knowledge and experience with various engineering tools and methodologies, such as Finite Element simulation, CAD modeling, and Systems Architecture modelling is a plus Ability to assist more junior developers on an as-needed basis Ability to learn quickly and to collaborate with others in a geographically distributed team Excellent communication and interpersonal skills At Ansys, we know that changing the world takes vision, skill, and each other. We fuel new ideas, build relationships, and help each other realize our greatest potential. We are ONE Ansys. We operate on three key components: our commitments to stakeholders, our values that guide how we work together, and our actions to deliver results. As ONE Ansys, we are powering innovation that drives human advancement Our Commitments:Amaze with innovative products and solutionsMake our customers incredibly successfulAct with integrityEnsure employees thrive and shareholders prosper Our Values:Adaptability: Be open, welcome what's nextCourage: Be courageous, move forward passionatelyGenerosity: Be generous, share, listen, serveAuthenticity: Be you, make us stronger Our Actions:We commit to audacious goalsWe work seamlessly as a teamWe demonstrate masteryWe deliver outstanding resultsVALUES IN ACTION Ansys is committed to powering the people who power human advancement. We believe in creating and nurturing a workplace that supports and welcomes people of all backgrounds; encouraging them to bring their talents and experience to a workplace where they are valued and can thrive. Our culture is grounded in our four core values of adaptability, courage, generosity, and authenticity. Through our behaviors and actions, these values foster higher team performance and greater innovation for our customers. We're proud to offer programs, available to all employees, to further impact innovation and business outcomes, such as employee networks and learning communities that inform solutions for our globally minded customer base. WELCOME WHAT'S NEXT IN YOUR CAREER AT ANSYS At Ansys, you will find yourself among the sharpest minds and most visionary leaders across the globe. Collectively, we strive to change the world with innovative technology and transformational solutions. With a prestigious reputation in working with well-known, world-class companies, standards at Ansys are high - met by those willing to rise to the occasion and meet those challenges head on. Our team is passionate about pushing the limits of world-class simulation technology, empowering our customers to turn their design concepts into successful, innovative products faster and at a lower cost. Ready to feel inspired? Check out some of our recent customer stories, here and here . At Ansys, it's about the learning, the discovery, and the collaboration. It's about the "what's next" as much as the "mission accomplished." And it's about the melding of disciplined intellect with strategic direction and results that have, can, and do impact real people in real ways. All this is forged within a working environment built on respect, autonomy, and ethics.CREATING A PLACE WE'RE PROUD TO BEAnsys is an S&P 500 company and a member of the NASDAQ-100. We are proud to have been recognized for the following more recent awards, although our list goes on: Newsweek's Most Loved Workplace globally and in the U.S., Gold Stevie Award Winner, America's Most Responsible Companies, Fast Company World Changing Ideas, Great Place to Work Certified.For more information, please visit us at Ansys is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other protected characteristics.Ansys does not accept unsolicited referrals for vacancies, and any unsolicited referral will become the property of Ansys. Upon hire, no fee will be owed to the agency, person, or entity.Apply NowLet's start your dream job Apply now Meet JobCopilot: Your Personal AI Job HunterAutomatically Apply to Remote Full-Stack Programming JobsJust set your preferences and Job Copilot will do the rest-finding, filtering, and applying while you focus on what matters. Activate JobCopilot
    #ansys #rampampd #engineer #remote #east
    Ansys: R&D Engineer II (Remote - East Coast, US)
    Requisition #: 16890 Our Mission: Powering Innovation That Drives Human Advancement When visionary companies need to know how their world-changing ideas will perform, they close the gap between design and reality with Ansys simulation. For more than 50 years, Ansys software has enabled innovators across industries to push boundaries by using the predictive power of simulation. From sustainable transportation to advanced semiconductors, from satellite systems to life-saving medical devices, the next great leaps in human advancement will be powered by Ansys. Innovate With Ansys, Power Your Career. Summary / Role Purpose The R&D Engineer II contributes to the development of software products and supporting systems. In this role, the R&D Engineer II will collaborate with a team of expert professionals to understand customer requirements and accomplish development objectives. Key Duties and Responsibilities Performs moderately complex development activities, including the design, implementation, maintenance, testing and documentation of software modules and sub-systems Understands and employs best practices Performs moderately complex bug verification, release testing and beta support for assigned products. Researches problems discovered by QA or product support and develops solutions Understands the marketing requirements for a product, including target environment, performance criteria and competitive issues Works under the general supervision of a development manager Minimum Education/Certification Requirements and Experience BS in Computer Science, Applied Mathematics, Engineering, or other natural science disciplines with 3-5 years' experience or MS with minimum 2 years experience Working experience within technical software development proven by academic, research, or industry projects. Good understanding and skills in object-oriented programming Experience with Java and C# / .NET Role can be remote, must be based on the East Coast due to timezone Preferred Qualifications and Skills Experience with C++, Python, in addition to Java and C# / .NET Knowledge of Task-Based Asynchronous design patternExposure to model-based systems engineering concepts Working knowledge of SysML Know-how on cloud computing technologies like micro-service architectures, RPC frameworks, REST APIs, etc. Knowledge of software security best practices Experience working on an Agile software development team Technical knowledge and experience with various engineering tools and methodologies, such as Finite Element simulation, CAD modeling, and Systems Architecture modelling is a plus Ability to assist more junior developers on an as-needed basis Ability to learn quickly and to collaborate with others in a geographically distributed team Excellent communication and interpersonal skills At Ansys, we know that changing the world takes vision, skill, and each other. We fuel new ideas, build relationships, and help each other realize our greatest potential. We are ONE Ansys. We operate on three key components: our commitments to stakeholders, our values that guide how we work together, and our actions to deliver results. As ONE Ansys, we are powering innovation that drives human advancement Our Commitments:Amaze with innovative products and solutionsMake our customers incredibly successfulAct with integrityEnsure employees thrive and shareholders prosper Our Values:Adaptability: Be open, welcome what's nextCourage: Be courageous, move forward passionatelyGenerosity: Be generous, share, listen, serveAuthenticity: Be you, make us stronger Our Actions:We commit to audacious goalsWe work seamlessly as a teamWe demonstrate masteryWe deliver outstanding resultsVALUES IN ACTION Ansys is committed to powering the people who power human advancement. We believe in creating and nurturing a workplace that supports and welcomes people of all backgrounds; encouraging them to bring their talents and experience to a workplace where they are valued and can thrive. Our culture is grounded in our four core values of adaptability, courage, generosity, and authenticity. Through our behaviors and actions, these values foster higher team performance and greater innovation for our customers. We're proud to offer programs, available to all employees, to further impact innovation and business outcomes, such as employee networks and learning communities that inform solutions for our globally minded customer base. WELCOME WHAT'S NEXT IN YOUR CAREER AT ANSYS At Ansys, you will find yourself among the sharpest minds and most visionary leaders across the globe. Collectively, we strive to change the world with innovative technology and transformational solutions. With a prestigious reputation in working with well-known, world-class companies, standards at Ansys are high - met by those willing to rise to the occasion and meet those challenges head on. Our team is passionate about pushing the limits of world-class simulation technology, empowering our customers to turn their design concepts into successful, innovative products faster and at a lower cost. Ready to feel inspired? Check out some of our recent customer stories, here and here . At Ansys, it's about the learning, the discovery, and the collaboration. It's about the "what's next" as much as the "mission accomplished." And it's about the melding of disciplined intellect with strategic direction and results that have, can, and do impact real people in real ways. All this is forged within a working environment built on respect, autonomy, and ethics.CREATING A PLACE WE'RE PROUD TO BEAnsys is an S&P 500 company and a member of the NASDAQ-100. We are proud to have been recognized for the following more recent awards, although our list goes on: Newsweek's Most Loved Workplace globally and in the U.S., Gold Stevie Award Winner, America's Most Responsible Companies, Fast Company World Changing Ideas, Great Place to Work Certified.For more information, please visit us at Ansys is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other protected characteristics.Ansys does not accept unsolicited referrals for vacancies, and any unsolicited referral will become the property of Ansys. Upon hire, no fee will be owed to the agency, person, or entity.Apply NowLet's start your dream job Apply now Meet JobCopilot: Your Personal AI Job HunterAutomatically Apply to Remote Full-Stack Programming JobsJust set your preferences and Job Copilot will do the rest-finding, filtering, and applying while you focus on what matters. Activate JobCopilot #ansys #rampampd #engineer #remote #east
    WEWORKREMOTELY.COM
    Ansys: R&D Engineer II (Remote - East Coast, US)
    Requisition #: 16890 Our Mission: Powering Innovation That Drives Human Advancement When visionary companies need to know how their world-changing ideas will perform, they close the gap between design and reality with Ansys simulation. For more than 50 years, Ansys software has enabled innovators across industries to push boundaries by using the predictive power of simulation. From sustainable transportation to advanced semiconductors, from satellite systems to life-saving medical devices, the next great leaps in human advancement will be powered by Ansys. Innovate With Ansys, Power Your Career. Summary / Role Purpose The R&D Engineer II contributes to the development of software products and supporting systems. In this role, the R&D Engineer II will collaborate with a team of expert professionals to understand customer requirements and accomplish development objectives. Key Duties and Responsibilities Performs moderately complex development activities, including the design, implementation, maintenance, testing and documentation of software modules and sub-systems Understands and employs best practices Performs moderately complex bug verification, release testing and beta support for assigned products. Researches problems discovered by QA or product support and develops solutions Understands the marketing requirements for a product, including target environment, performance criteria and competitive issues Works under the general supervision of a development manager Minimum Education/Certification Requirements and Experience BS in Computer Science, Applied Mathematics, Engineering, or other natural science disciplines with 3-5 years' experience or MS with minimum 2 years experience Working experience within technical software development proven by academic, research, or industry projects. Good understanding and skills in object-oriented programming Experience with Java and C# / .NET Role can be remote, must be based on the East Coast due to timezone Preferred Qualifications and Skills Experience with C++, Python, in addition to Java and C# / .NET Knowledge of Task-Based Asynchronous design pattern (TAP) Exposure to model-based systems engineering concepts Working knowledge of SysML Know-how on cloud computing technologies like micro-service architectures, RPC frameworks (e.g., gRPC), REST APIs, etc. Knowledge of software security best practices Experience working on an Agile software development team Technical knowledge and experience with various engineering tools and methodologies, such as Finite Element simulation, CAD modeling, and Systems Architecture modelling is a plus Ability to assist more junior developers on an as-needed basis Ability to learn quickly and to collaborate with others in a geographically distributed team Excellent communication and interpersonal skills At Ansys, we know that changing the world takes vision, skill, and each other. We fuel new ideas, build relationships, and help each other realize our greatest potential. We are ONE Ansys. We operate on three key components: our commitments to stakeholders, our values that guide how we work together, and our actions to deliver results. As ONE Ansys, we are powering innovation that drives human advancement Our Commitments:Amaze with innovative products and solutionsMake our customers incredibly successfulAct with integrityEnsure employees thrive and shareholders prosper Our Values:Adaptability: Be open, welcome what's nextCourage: Be courageous, move forward passionatelyGenerosity: Be generous, share, listen, serveAuthenticity: Be you, make us stronger Our Actions:We commit to audacious goalsWe work seamlessly as a teamWe demonstrate masteryWe deliver outstanding resultsVALUES IN ACTION Ansys is committed to powering the people who power human advancement. We believe in creating and nurturing a workplace that supports and welcomes people of all backgrounds; encouraging them to bring their talents and experience to a workplace where they are valued and can thrive. Our culture is grounded in our four core values of adaptability, courage, generosity, and authenticity. Through our behaviors and actions, these values foster higher team performance and greater innovation for our customers. We're proud to offer programs, available to all employees, to further impact innovation and business outcomes, such as employee networks and learning communities that inform solutions for our globally minded customer base. WELCOME WHAT'S NEXT IN YOUR CAREER AT ANSYS At Ansys, you will find yourself among the sharpest minds and most visionary leaders across the globe. Collectively, we strive to change the world with innovative technology and transformational solutions. With a prestigious reputation in working with well-known, world-class companies, standards at Ansys are high - met by those willing to rise to the occasion and meet those challenges head on. Our team is passionate about pushing the limits of world-class simulation technology, empowering our customers to turn their design concepts into successful, innovative products faster and at a lower cost. Ready to feel inspired? Check out some of our recent customer stories, here and here . At Ansys, it's about the learning, the discovery, and the collaboration. It's about the "what's next" as much as the "mission accomplished." And it's about the melding of disciplined intellect with strategic direction and results that have, can, and do impact real people in real ways. All this is forged within a working environment built on respect, autonomy, and ethics.CREATING A PLACE WE'RE PROUD TO BEAnsys is an S&P 500 company and a member of the NASDAQ-100. We are proud to have been recognized for the following more recent awards, although our list goes on: Newsweek's Most Loved Workplace globally and in the U.S., Gold Stevie Award Winner, America's Most Responsible Companies, Fast Company World Changing Ideas, Great Place to Work Certified (China, Greece, France, India, Japan, Korea, Spain, Sweden, Taiwan, and U.K.).For more information, please visit us at Ansys is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other protected characteristics.Ansys does not accept unsolicited referrals for vacancies, and any unsolicited referral will become the property of Ansys. Upon hire, no fee will be owed to the agency, person, or entity.Apply NowLet's start your dream job Apply now Meet JobCopilot: Your Personal AI Job HunterAutomatically Apply to Remote Full-Stack Programming JobsJust set your preferences and Job Copilot will do the rest-finding, filtering, and applying while you focus on what matters. Activate JobCopilot
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  • Summer Game Fest 2025 Saw 89 Percent Growth in Live Concurrent Viewership Since Last Year

    The recent Summer Game Fest 2025 has been quite successful. According to Variety, the live stream saw a massive growth year-over-year in terms of live viewership, coming in at an increase of 89 percent since the 2024 edition.
    The event saw a number of new games announced, as well as trailers for previously-announced games that will be coming soon. Among the headliners for the event were titles like Capcom’s Resident Evil Requiem, as well as gameplay for IO Interactive’s 007: First Light.
    “In total, the peak concurrent audience for SGF reached more than 3 million live simultaneous viewers across Twitch and YouTube, with significant year over year growth on both platforms in terms of average viewership, watch time and co-streams,” announced Summer Game Fest in a press release over the weekend.
    At the time of publishing Summer Game Fest 2025 had managed to get 8.5 million views on just one of the places where it was hosted – the official The Game Awards channel. While it is worth noting that this number takes both the live stream audience as well as those who watched the event afterwards into account, the number would quite likely be higher when taking other hosts, and even platforms like Twitch into account.
    Reports, have indicated that of the 8.5 million viewers, 1.5 million could be attributed to those watching during the live stream globally. Twitch, on the other hand, saw a growth of 38 percent in terms of live viewership among the over 8,900 channels that were co-streaming the event. This came in to around 1.4 million concurrent live viewers worldwide.
    Summer Games Fest 2025 was accompanied by a host of other events happening over the same weekend. This included events focused on PC Gaming, as well as Microsoft’s own Xbox Games Showcase, and even the indie game-focused Future Games Show 2025.
    Coinciding with the events was Valve kicking of its latest edition of Steam Next Fest, which featured a host of different game demos that players could try out. A lot of these games were unveiled or otherwise got new trailers during the live events last weekend. However, it is worth noting that today is the final day of this iteration of Steam Next Fest, which means that a lot of the demos will be going away.
    #summer #game #fest #saw #percent
    Summer Game Fest 2025 Saw 89 Percent Growth in Live Concurrent Viewership Since Last Year
    The recent Summer Game Fest 2025 has been quite successful. According to Variety, the live stream saw a massive growth year-over-year in terms of live viewership, coming in at an increase of 89 percent since the 2024 edition. The event saw a number of new games announced, as well as trailers for previously-announced games that will be coming soon. Among the headliners for the event were titles like Capcom’s Resident Evil Requiem, as well as gameplay for IO Interactive’s 007: First Light. “In total, the peak concurrent audience for SGF reached more than 3 million live simultaneous viewers across Twitch and YouTube, with significant year over year growth on both platforms in terms of average viewership, watch time and co-streams,” announced Summer Game Fest in a press release over the weekend. At the time of publishing Summer Game Fest 2025 had managed to get 8.5 million views on just one of the places where it was hosted – the official The Game Awards channel. While it is worth noting that this number takes both the live stream audience as well as those who watched the event afterwards into account, the number would quite likely be higher when taking other hosts, and even platforms like Twitch into account. Reports, have indicated that of the 8.5 million viewers, 1.5 million could be attributed to those watching during the live stream globally. Twitch, on the other hand, saw a growth of 38 percent in terms of live viewership among the over 8,900 channels that were co-streaming the event. This came in to around 1.4 million concurrent live viewers worldwide. Summer Games Fest 2025 was accompanied by a host of other events happening over the same weekend. This included events focused on PC Gaming, as well as Microsoft’s own Xbox Games Showcase, and even the indie game-focused Future Games Show 2025. Coinciding with the events was Valve kicking of its latest edition of Steam Next Fest, which featured a host of different game demos that players could try out. A lot of these games were unveiled or otherwise got new trailers during the live events last weekend. However, it is worth noting that today is the final day of this iteration of Steam Next Fest, which means that a lot of the demos will be going away. #summer #game #fest #saw #percent
    GAMINGBOLT.COM
    Summer Game Fest 2025 Saw 89 Percent Growth in Live Concurrent Viewership Since Last Year
    The recent Summer Game Fest 2025 has been quite successful. According to Variety, the live stream saw a massive growth year-over-year in terms of live viewership, coming in at an increase of 89 percent since the 2024 edition. The event saw a number of new games announced, as well as trailers for previously-announced games that will be coming soon. Among the headliners for the event were titles like Capcom’s Resident Evil Requiem, as well as gameplay for IO Interactive’s 007: First Light. “In total, the peak concurrent audience for SGF reached more than 3 million live simultaneous viewers across Twitch and YouTube, with significant year over year growth on both platforms in terms of average viewership, watch time and co-streams,” announced Summer Game Fest in a press release over the weekend. At the time of publishing Summer Game Fest 2025 had managed to get 8.5 million views on just one of the places where it was hosted – the official The Game Awards channel. While it is worth noting that this number takes both the live stream audience as well as those who watched the event afterwards into account, the number would quite likely be higher when taking other hosts, and even platforms like Twitch into account. Reports, have indicated that of the 8.5 million viewers, 1.5 million could be attributed to those watching during the live stream globally. Twitch, on the other hand, saw a growth of 38 percent in terms of live viewership among the over 8,900 channels that were co-streaming the event. This came in to around 1.4 million concurrent live viewers worldwide. Summer Games Fest 2025 was accompanied by a host of other events happening over the same weekend. This included events focused on PC Gaming, as well as Microsoft’s own Xbox Games Showcase, and even the indie game-focused Future Games Show 2025. Coinciding with the events was Valve kicking of its latest edition of Steam Next Fest, which featured a host of different game demos that players could try out. A lot of these games were unveiled or otherwise got new trailers during the live events last weekend. However, it is worth noting that today is the final day of this iteration of Steam Next Fest, which means that a lot of the demos will be going away.
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  • Summer Game Fest Viewership Jumps 89% to Record 50 Million Livestreams

    The 2025 edition of Summer Game Fest saw an 89% year-over-year growth in live peak viewership, according to StreamsCharts.

    Airing live across YouTube, Twitch and Xon June 6, the Geoff Keighley-hosted video game showcase, which was held out of the YouTube Theater at SoFi Stadium in Los Angeles, reached more than 50 million livestreams. That marks a record high in viewership for the event, which is now in its sixth year.

    Related Stories

    Major games announced or further teased during the show included the reveal of “Resident Evil Requiem,” “Atomic Heart 2,” “Scott Pilgrim EX,” “Mouse: P.I. for Hire,” “Game of Thrones: War for Westeros,” “Marvel’s Deadpool VR,” “007 First Light,” “Death Stranding 2: On the Beach” and “ARC Raiders.”

    Popular on Variety

    SEE ALSO: Variety’s Summer Game Fest Recap

    Per a Friday press release from Summer Game Fest, which is produced by Keighley and iam8bit, “In total, the peak concurrent audience for SGF reached more than 3 million live simultaneous viewers across Twitch and YouTube, with significant year over year growth on both platforms in terms of average viewership, watch time and co-streams.”

    Peak viewership stood on YouTubewas up 43% compared to 2024, with the average audience up 38%, per StreamCharts data provided by SGF.

    The archived video version of the live show has currently racked up more than eight million views. In total, the peak concurrent audience on YouTube reached over 1.5 million viewers globally,

    On gaming-focused social media platform Twitch, peak viewership for SGF was up 38% with more than 8,900 channels co-streaming the show. The total concurrent live audience stood at more than 1.4 million viewers worldwide.

    SGF was the top global trend on X/Twitter with 17 out of the top 30 trends in the U.S. related to Summer Game Fest, per the event.
    #summer #game #fest #viewership #jumps
    Summer Game Fest Viewership Jumps 89% to Record 50 Million Livestreams
    The 2025 edition of Summer Game Fest saw an 89% year-over-year growth in live peak viewership, according to StreamsCharts. Airing live across YouTube, Twitch and Xon June 6, the Geoff Keighley-hosted video game showcase, which was held out of the YouTube Theater at SoFi Stadium in Los Angeles, reached more than 50 million livestreams. That marks a record high in viewership for the event, which is now in its sixth year. Related Stories Major games announced or further teased during the show included the reveal of “Resident Evil Requiem,” “Atomic Heart 2,” “Scott Pilgrim EX,” “Mouse: P.I. for Hire,” “Game of Thrones: War for Westeros,” “Marvel’s Deadpool VR,” “007 First Light,” “Death Stranding 2: On the Beach” and “ARC Raiders.” Popular on Variety SEE ALSO: Variety’s Summer Game Fest Recap Per a Friday press release from Summer Game Fest, which is produced by Keighley and iam8bit, “In total, the peak concurrent audience for SGF reached more than 3 million live simultaneous viewers across Twitch and YouTube, with significant year over year growth on both platforms in terms of average viewership, watch time and co-streams.” Peak viewership stood on YouTubewas up 43% compared to 2024, with the average audience up 38%, per StreamCharts data provided by SGF. The archived video version of the live show has currently racked up more than eight million views. In total, the peak concurrent audience on YouTube reached over 1.5 million viewers globally, On gaming-focused social media platform Twitch, peak viewership for SGF was up 38% with more than 8,900 channels co-streaming the show. The total concurrent live audience stood at more than 1.4 million viewers worldwide. SGF was the top global trend on X/Twitter with 17 out of the top 30 trends in the U.S. related to Summer Game Fest, per the event. #summer #game #fest #viewership #jumps
    VARIETY.COM
    Summer Game Fest Viewership Jumps 89% to Record 50 Million Livestreams
    The 2025 edition of Summer Game Fest saw an 89% year-over-year growth in live peak viewership, according to StreamsCharts. Airing live across YouTube, Twitch and X (formerly Twitter) on June 6, the Geoff Keighley-hosted video game showcase, which was held out of the YouTube Theater at SoFi Stadium in Los Angeles, reached more than 50 million livestreams. That marks a record high in viewership for the event, which is now in its sixth year. Related Stories Major games announced or further teased during the show included the reveal of “Resident Evil Requiem,” “Atomic Heart 2,” “Scott Pilgrim EX,” “Mouse: P.I. for Hire,” “Game of Thrones: War for Westeros,” “Marvel’s Deadpool VR,” “007 First Light,” “Death Stranding 2: On the Beach” and “ARC Raiders.” Popular on Variety SEE ALSO: Variety’s Summer Game Fest Recap Per a Friday press release from Summer Game Fest, which is produced by Keighley and iam8bit, “In total, the peak concurrent audience for SGF reached more than 3 million live simultaneous viewers across Twitch and YouTube, with significant year over year growth on both platforms in terms of average viewership, watch time and co-streams.” Peak viewership stood on YouTube (via account for The Game Awards, which is the sister event to Summer Game Fest and is used as the feed for the SGF livestream as well) was up 43% compared to 2024, with the average audience up 38%, per StreamCharts data provided by SGF. The archived video version of the live show has currently racked up more than eight million views. In total, the peak concurrent audience on YouTube reached over 1.5 million viewers globally, On gaming-focused social media platform Twitch, peak viewership for SGF was up 38% with more than 8,900 channels co-streaming the show. The total concurrent live audience stood at more than 1.4 million viewers worldwide. SGF was the top global trend on X/Twitter with 17 out of the top 30 trends in the U.S. related to Summer Game Fest, per the event.
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  • How AI is reshaping the future of healthcare and medical research

    Transcript       
    PETER LEE: “In ‘The Little Black Bag,’ a classic science fiction story, a high-tech doctor’s kit of the future is accidentally transported back to the 1950s, into the shaky hands of a washed-up, alcoholic doctor. The ultimate medical tool, it redeems the doctor wielding it, allowing him to practice gratifyingly heroic medicine. … The tale ends badly for the doctor and his treacherous assistant, but it offered a picture of how advanced technology could transform medicine—powerful when it was written nearly 75 years ago and still so today. What would be the Al equivalent of that little black bag? At this moment when new capabilities are emerging, how do we imagine them into medicine?”          
    This is The AI Revolution in Medicine, Revisited. I’m your host, Peter Lee.   
    Shortly after OpenAI’s GPT-4 was publicly released, Carey Goldberg, Dr. Zak Kohane, and I published The AI Revolution in Medicine to help educate the world of healthcare and medical research about the transformative impact this new generative AI technology could have. But because we wrote the book when GPT-4 was still a secret, we had to speculate. Now, two years later, what did we get right, and what did we get wrong?    
    In this series, we’ll talk to clinicians, patients, hospital administrators, and others to understand the reality of AI in the field and where we go from here.  The book passage I read at the top is from “Chapter 10: The Big Black Bag.” 
    In imagining AI in medicine, Carey, Zak, and I included in our book two fictional accounts. In the first, a medical resident consults GPT-4 on her personal phone as the patient in front of her crashes. Within seconds, it offers an alternate response based on recent literature. In the second account, a 90-year-old woman with several chronic conditions is living independently and receiving near-constant medical support from an AI aide.   
    In our conversations with the guests we’ve spoken to so far, we’ve caught a glimpse of these predicted futures, seeing how clinicians and patients are actually using AI today and how developers are leveraging the technology in the healthcare products and services they’re creating. In fact, that first fictional account isn’t so fictional after all, as most of the doctors in the real world actually appear to be using AI at least occasionally—and sometimes much more than occasionally—to help in their daily clinical work. And as for the second fictional account, which is more of a science fiction account, it seems we are indeed on the verge of a new way of delivering and receiving healthcare, though the future is still very much open. 
    As we continue to examine the current state of AI in healthcare and its potential to transform the field, I’m pleased to welcome Bill Gates and Sébastien Bubeck.  
    Bill may be best known as the co-founder of Microsoft, having created the company with his childhood friend Paul Allen in 1975. He’s now the founder of Breakthrough Energy, which aims to advance clean energy innovation, and TerraPower, a company developing groundbreaking nuclear energy and science technologies. He also chairs the world’s largest philanthropic organization, the Gates Foundation, and focuses on solving a variety of health challenges around the globe and here at home. 
    Sébastien is a research lead at OpenAI. He was previously a distinguished scientist, vice president of AI, and a colleague of mine here at Microsoft, where his work included spearheading the development of the family of small language models known as Phi. While at Microsoft, he also coauthored the discussion-provoking 2023 paper “Sparks of Artificial General Intelligence,” which presented the results of early experiments with GPT-4 conducted by a small team from Microsoft Research.     
    Here’s my conversation with Bill Gates and Sébastien Bubeck. 
    LEE: Bill, welcome. 
    BILL GATES: Thank you. 
    LEE: Seb … 
    SÉBASTIEN BUBECK: Yeah. Hi, hi, Peter. Nice to be here. 
    LEE: You know, one of the things that I’ve been doing just to get the conversation warmed up is to talk about origin stories, and what I mean about origin stories is, you know, what was the first contact that you had with large language models or the concept of generative AI that convinced you or made you think that something really important was happening? 
    And so, Bill, I think I’ve heard the story about, you know, the time when the OpenAI folks—Sam Altman, Greg Brockman, and others—showed you something, but could we hear from you what those early encounters were like and what was going through your mind?  
    GATES: Well, I’d been visiting OpenAI soon after it was created to see things like GPT-2 and to see the little arm they had that was trying to match human manipulation and, you know, looking at their games like Dota that they were trying to get as good as human play. And honestly, I didn’t think the language model stuff they were doing, even when they got to GPT-3, would show the ability to learn, you know, in the same sense that a human reads a biology book and is able to take that knowledge and access it not only to pass a test but also to create new medicines. 
    And so my challenge to them was that if their LLM could get a five on the advanced placement biology test, then I would say, OK, it took biologic knowledge and encoded it in an accessible way and that I didn’t expect them to do that very quickly but it would be profound.  
    And it was only about six months after I challenged them to do that, that an early version of GPT-4 they brought up to a dinner at my house, and in fact, it answered most of the questions that night very well. The one it got totally wrong, we were … because it was so good, we kept thinking, Oh, we must be wrong. It turned out it was a math weaknessthat, you know, we later understood that that was an area of, weirdly, of incredible weakness of those early models. But, you know, that was when I realized, OK, the age of cheap intelligence was at its beginning. 
    LEE: Yeah. So I guess it seems like you had something similar to me in that my first encounters, I actually harbored some skepticism. Is it fair to say you were skeptical before that? 
    GATES: Well, the idea that we’ve figured out how to encode and access knowledge in this very deep sense without even understanding the nature of the encoding, … 
    LEE: Right.  
    GATES: … that is a bit weird.  
    LEE: Yeah. 
    GATES: We have an algorithm that creates the computation, but even say, OK, where is the president’s birthday stored in there? Where is this fact stored in there? The fact that even now when we’re playing around, getting a little bit more sense of it, it’s opaque to us what the semantic encoding is, it’s, kind of, amazing to me. I thought the invention of knowledge storage would be an explicit way of encoding knowledge, not an implicit statistical training. 
    LEE: Yeah, yeah. All right. So, Seb, you know, on this same topic, you know, I got—as we say at Microsoft—I got pulled into the tent. 
    BUBECK: Yes.  
    LEE: Because this was a very secret project. And then, um, I had the opportunity to select a small number of researchers in MSRto join and start investigating this thing seriously. And the first person I pulled in was you. 
    BUBECK: Yeah. 
    LEE: And so what were your first encounters? Because I actually don’t remember what happened then. 
    BUBECK: Oh, I remember it very well.My first encounter with GPT-4 was in a meeting with the two of you, actually. But my kind of first contact, the first moment where I realized that something was happening with generative AI, was before that. And I agree with Bill that I also wasn’t too impressed by GPT-3. 
    I though that it was kind of, you know, very naturally mimicking the web, sort of parroting what was written there in a nice way. Still in a way which seemed very impressive. But it wasn’t really intelligent in any way. But shortly after GPT-3, there was a model before GPT-4 that really shocked me, and this was the first image generation model, DALL-E 1. 
    So that was in 2021. And I will forever remember the press release of OpenAI where they had this prompt of an avocado chair and then you had this image of the avocado chair.And what really shocked me is that clearly the model kind of “understood” what is a chair, what is an avocado, and was able to merge those concepts. 
    So this was really, to me, the first moment where I saw some understanding in those models.  
    LEE: So this was, just to get the timing right, that was before I pulled you into the tent. 
    BUBECK: That was before. That was like a year before. 
    LEE: Right.  
    BUBECK: And now I will tell you how, you know, we went from that moment to the meeting with the two of you and GPT-4. 
    So once I saw this kind of understanding, I thought, OK, fine. It understands concept, but it’s still not able to reason. It cannot—as, you know, Bill was saying—it cannot learn from your document. It cannot reason.  
    So I set out to try to prove that. You know, this is what I was in the business of at the time, trying to prove things in mathematics. So I was trying to prove that basically autoregressive transformers could never reason. So I was trying to prove this. And after a year of work, I had something reasonable to show. And so I had the meeting with the two of you, and I had this example where I wanted to say, there is no way that an LLM is going to be able to do x. 
    And then as soon as I … I don’t know if you remember, Bill. But as soon as I said that, you said, oh, but wait a second. I had, you know, the OpenAI crew at my house recently, and they showed me a new model. Why don’t we ask this new model this question?  
    LEE: Yeah.
    BUBECK: And we did, and it solved it on the spot. And that really, honestly, just changed my life. Like, you know, I had been working for a year trying to say that this was impossible. And just right there, it was shown to be possible.  
    LEE:One of the very first things I got interested in—because I was really thinking a lot about healthcare—was healthcare and medicine. 
    And I don’t know if the two of you remember, but I ended up doing a lot of tests. I ran through, you know, step one and step two of the US Medical Licensing Exam. Did a whole bunch of other things. I wrote this big report. It was, you know, I can’t remember … a couple hundred pages.  
    And I needed to share this with someone. I didn’t … there weren’t too many people I could share it with. So I sent, I think, a copy to you, Bill. Sent a copy to you, Seb.  
    I hardly slept for about a week putting that report together. And, yeah, and I kept working on it. But I was far from alone. I think everyone who was in the tent, so to speak, in those early days was going through something pretty similar. All right. So I think … of course, a lot of what I put in the report also ended up being examples that made it into the book. 
    But the main purpose of this conversation isn’t to reminisce aboutor indulge in those reminiscences but to talk about what’s happening in healthcare and medicine. And, you know, as I said, we wrote this book. We did it very, very quickly. Seb, you helped. Bill, you know, you provided a review and some endorsements. 
    But, you know, honestly, we didn’t know what we were talking about because no one had access to this thing. And so we just made a bunch of guesses. So really, the whole thing I wanted to probe with the two of you is, now with two years of experience out in the world, what, you know, what do we think is happening today? 
    You know, is AI actually having an impact, positive or negative, on healthcare and medicine? And what do we now think is going to happen in the next two years, five years, or 10 years? And so I realize it’s a little bit too abstract to just ask it that way. So let me just try to narrow the discussion and guide us a little bit.  
    Um, the kind of administrative and clerical work, paperwork, around healthcare—and we made a lot of guesses about that—that appears to be going well, but, you know, Bill, I know we’ve discussed that sometimes that you think there ought to be a lot more going on. Do you have a viewpoint on how AI is actually finding its way into reducing paperwork? 
    GATES: Well, I’m stunned … I don’t think there should be a patient-doctor meeting where the AI is not sitting in and both transcribing, offering to help with the paperwork, and even making suggestions, although the doctor will be the one, you know, who makes the final decision about the diagnosis and whatever prescription gets done.  
    It’s so helpful. You know, when that patient goes home and their, you know, son who wants to understand what happened has some questions, that AI should be available to continue that conversation. And the way you can improve that experience and streamline things and, you know, involve the people who advise you. I don’t understand why that’s not more adopted, because there you still have the human in the loop making that final decision. 
    But even for, like, follow-up calls to make sure the patient did things, to understand if they have concerns and knowing when to escalate back to the doctor, the benefit is incredible. And, you know, that thing is ready for prime time. That paradigm is ready for prime time, in my view. 
    LEE: Yeah, there are some good products, but it seems like the number one use right now—and we kind of got this from some of the previous guests in previous episodes—is the use of AI just to respond to emails from patients.Does that make sense to you? 
    BUBECK: Yeah. So maybe I want to second what Bill was saying but maybe take a step back first. You know, two years ago, like, the concept of clinical scribes, which is one of the things that we’re talking about right now, it would have sounded, in fact, it sounded two years ago, borderline dangerous. Because everybody was worried about hallucinations. What happened if you have this AI listening in and then it transcribes, you know, something wrong? 
    Now, two years later, I think it’s mostly working. And in fact, it is not yet, you know, fully adopted. You’re right. But it is in production. It is used, you know, in many, many places. So this rate of progress is astounding because it wasn’t obvious that we would be able to overcome those obstacles of hallucination. It’s not to say that hallucinations are fully solved. In the case of the closed system, they are.  
    Now, I think more generally what’s going on in the background is that there is something that we, that certainly I, underestimated, which is this management overhead. So I think the reason why this is not adopted everywhere is really a training and teaching aspect. People need to be taught, like, those systems, how to interact with them. 
    And one example that I really like, a study that recently appeared where they tried to use ChatGPT for diagnosis and they were comparing doctors without and with ChatGPT. And the amazing thing … so this was a set of cases where the accuracy of the doctors alone was around 75%. ChatGPT alone was 90%. So that’s already kind of mind blowing. But then the kicker is that doctors with ChatGPT was 80%.  
    Intelligence alone is not enough. It’s also how it’s presented, how you interact with it. And ChatGPT, it’s an amazing tool. Obviously, I absolutely love it. But it’s not … you don’t want a doctor to have to type in, you know, prompts and use it that way. 
    It should be, as Bill was saying, kind of running continuously in the background, sending you notifications. And you have to be really careful of the rate at which those notifications are being sent. Because if they are too frequent, then the doctor will learn to ignore them. So you have to … all of those things matter, in fact, at least as much as the level of intelligence of the machine. 
    LEE: One of the things I think about, Bill, in that scenario that you described, doctors do some thinking about the patient when they write the note. So, you know, I’m always a little uncertain whether it’s actually … you know, you wouldn’t necessarily want to fully automate this, I don’t think. Or at least there needs to be some prompt to the doctor to make sure that the doctor puts some thought into what happened in the encounter with the patient. Does that make sense to you at all? 
    GATES: At this stage, you know, I’d still put the onus on the doctor to write the conclusions and the summary and not delegate that. 
    The tradeoffs you make a little bit are somewhat dependent on the situation you’re in. If you’re in Africa,
    So, yes, the doctor’s still going to have to do a lot of work, but just the quality of letting the patient and the people around them interact and ask questions and have things explained, that alone is such a quality improvement. It’s mind blowing.  
    LEE: So since you mentioned, you know, Africa—and, of course, this touches on the mission and some of the priorities of the Gates Foundation and this idea of democratization of access to expert medical care—what’s the most interesting stuff going on right now? Are there people and organizations or technologies that are impressing you or that you’re tracking? 
    GATES: Yeah. So the Gates Foundation has given out a lot of grants to people in Africa doing education, agriculture but more healthcare examples than anything. And the way these things start off, they often start out either being patient-centric in a narrow situation, like, OK, I’m a pregnant woman; talk to me. Or, I have infectious disease symptoms; talk to me. Or they’re connected to a health worker where they’re helping that worker get their job done. And we have lots of pilots out, you know, in both of those cases.  
    The dream would be eventually to have the thing the patient consults be so broad that it’s like having a doctor available who understands the local things.  
    LEE: Right.  
    GATES: We’re not there yet. But over the next two or three years, you know, particularly given the worsening financial constraints against African health systems, where the withdrawal of money has been dramatic, you know, figuring out how to take this—what I sometimes call “free intelligence”—and build a quality health system around that, we will have to be more radical in low-income countries than any rich country is ever going to be.  
    LEE: Also, there’s maybe a different regulatory environment, so some of those things maybe are easier? Because right now, I think the world hasn’t figured out how to and whether to regulate, let’s say, an AI that might give a medical diagnosis or write a prescription for a medication. 
    BUBECK: Yeah. I think one issue with this, and it’s also slowing down the deployment of AI in healthcare more generally, is a lack of proper benchmark. Because, you know, you were mentioning the USMLE, for example. That’s a great test to test human beings and their knowledge of healthcare and medicine. But it’s not a great test to give to an AI. 
    It’s not asking the right questions. So finding what are the right questions to test whether an AI system is ready to give diagnosis in a constrained setting, that’s a very, very important direction, which to my surprise, is not yet accelerating at the rate that I was hoping for. 
    LEE: OK, so that gives me an excuse to get more now into the core AI tech because something I’ve discussed with both of you is this issue of what are the right tests. And you both know the very first test I give to any new spin of an LLM is I present a patient, the results—a mythical patient—the results of my physical exam, my mythical physical exam. Maybe some results of some initial labs. And then I present or propose a differential diagnosis. And if you’re not in medicine, a differential diagnosis you can just think of as a prioritized list of the possible diagnoses that fit with all that data. And in that proposed differential, I always intentionally make two mistakes. 
    I make a textbook technical error in one of the possible elements of the differential diagnosis, and I have an error of omission. And, you know, I just want to know, does the LLM understand what I’m talking about? And all the good ones out there do now. But then I want to know, can it spot the errors? And then most importantly, is it willing to tell me I’m wrong, that I’ve made a mistake?  
    That last piece seems really hard for AI today. And so let me ask you first, Seb, because at the time of this taping, of course, there was a new spin of GPT-4o last week that became overly sycophantic. In other words, it was actually prone in that test of mine not only to not tell me I’m wrong, but it actually praised me for the creativity of my differential.What’s up with that? 
    BUBECK: Yeah, I guess it’s a testament to the fact that training those models is still more of an art than a science. So it’s a difficult job. Just to be clear with the audience, we have rolled back thatversion of GPT-4o, so now we don’t have the sycophant version out there. 
    Yeah, no, it’s a really difficult question. It has to do … as you said, it’s very technical. It has to do with the post-training and how, like, where do you nudge the model? So, you know, there is this very classical by now technique called RLHF, where you push the model in the direction of a certain reward model. So the reward model is just telling the model, you know, what behavior is good, what behavior is bad. 
    But this reward model is itself an LLM, and, you know, Bill was saying at the very beginning of the conversation that we don’t really understand how those LLMs deal with concepts like, you know, where is the capital of France located? Things like that. It is the same thing for this reward model. We don’t know why it says that it prefers one output to another, and whether this is correlated with some sycophancy is, you know, something that we discovered basically just now. That if you push too hard in optimization on this reward model, you will get a sycophant model. 
    So it’s kind of … what I’m trying to say is we became too good at what we were doing, and we ended up, in fact, in a trap of the reward model. 
    LEE: I mean, you do want … it’s a difficult balance because you do want models to follow your desires and … 
    BUBECK: It’s a very difficult, very difficult balance. 
    LEE: So this brings up then the following question for me, which is the extent to which we think we’ll need to have specially trained models for things. So let me start with you, Bill. Do you have a point of view on whether we will need to, you know, quote-unquote take AI models to med school? Have them specially trained? Like, if you were going to deploy something to give medical care in underserved parts of the world, do we need to do something special to create those models? 
    GATES: We certainly need to teach them the African languages and the unique dialects so that the multimedia interactions are very high quality. We certainly need to teach them the disease prevalence and unique disease patterns like, you know, neglected tropical diseases and malaria. So we need to gather a set of facts that somebody trying to go for a US customer base, you know, wouldn’t necessarily have that in there. 
    Those two things are actually very straightforward because the additional training time is small. I’d say for the next few years, we’ll also need to do reinforcement learning about the context of being a doctor and how important certain behaviors are. Humans learn over the course of their life to some degree that, I’m in a different context and the way I behave in terms of being willing to criticize or be nice, you know, how important is it? Who’s here? What’s my relationship to them?  
    Right now, these machines don’t have that broad social experience. And so if you know it’s going to be used for health things, a lot of reinforcement learning of the very best humans in that context would still be valuable. Eventually, the models will, having read all the literature of the world about good doctors, bad doctors, it’ll understand as soon as you say, “I want you to be a doctor diagnosing somebody.” All of the implicit reinforcement that fits that situation, you know, will be there.
    LEE: Yeah.
    GATES: And so I hope three years from now, we don’t have to do that reinforcement learning. But today, for any medical context, you would want a lot of data to reinforce tone, willingness to say things when, you know, there might be something significant at stake. 
    LEE: Yeah. So, you know, something Bill said, kind of, reminds me of another thing that I think we missed, which is, the context also … and the specialization also pertains to different, I guess, what we still call “modes,” although I don’t know if the idea of multimodal is the same as it was two years ago. But, you know, what do you make of all of the hubbub around—in fact, within Microsoft Research, this is a big deal, but I think we’re far from alone—you know, medical images and vision, video, proteins and molecules, cell, you know, cellular data and so on. 
    BUBECK: Yeah. OK. So there is a lot to say to everything … to the last, you know, couple of minutes. Maybe on the specialization aspect, you know, I think there is, hiding behind this, a really fundamental scientific question of whether eventually we have a singular AGIthat kind of knows everything and you can just put, you know, explain your own context and it will just get it and understand everything. 
    That’s one vision. I have to say, I don’t particularly believe in this vision. In fact, we humans are not like that at all. I think, hopefully, we are general intelligences, yet we have to specialize a lot. And, you know, I did myself a lot of RL, reinforcement learning, on mathematics. Like, that’s what I did, you know, spent a lot of time doing that. And I didn’t improve on other aspects. You know, in fact, I probably degraded in other aspects.So it’s … I think it’s an important example to have in mind. 
    LEE: I think I might disagree with you on that, though, because, like, doesn’t a model have to see both good science and bad science in order to be able to gain the ability to discern between the two? 
    BUBECK: Yeah, no, that absolutely. I think there is value in seeing the generality, in having a very broad base. But then you, kind of, specialize on verticals. And this is where also, you know, open-weights model, which we haven’t talked about yet, are really important because they allow you to provide this broad base to everyone. And then you can specialize on top of it. 
    LEE: So we have about three hours of stuff to talk about, but our time is actually running low.
    BUBECK: Yes, yes, yes.  
    LEE: So I think I want … there’s a more provocative question. It’s almost a silly question, but I need to ask it of the two of you, which is, is there a future, you know, where AI replaces doctors or replaces, you know, medical specialties that we have today? So what does the world look like, say, five years from now? 
    GATES: Well, it’s important to distinguish healthcare discovery activity from healthcare delivery activity. We focused mostly on delivery. I think it’s very much within the realm of possibility that the AI is not only accelerating healthcare discovery but substituting for a lot of the roles of, you know, I’m an organic chemist, or I run various types of assays. I can see those, which are, you know, testable-output-type jobs but with still very high value, I can see, you know, some replacement in those areas before the doctor.  
    The doctor, still understanding the human condition and long-term dialogues, you know, they’ve had a lifetime of reinforcement of that, particularly when you get into areas like mental health. So I wouldn’t say in five years, either people will choose to adopt it, but it will be profound that there’ll be this nearly free intelligence that can do follow-up, that can help you, you know, make sure you went through different possibilities. 
    And so I’d say, yes, we’ll have doctors, but I’d say healthcare will be massively transformed in its quality and in efficiency by AI in that time period. 
    LEE: Is there a comparison, useful comparison, say, between doctors and, say, programmers, computer programmers, or doctors and, I don’t know, lawyers? 
    GATES: Programming is another one that has, kind of, a mathematical correctness to it, you know, and so the objective function that you’re trying to reinforce to, as soon as you can understand the state machines, you can have something that’s “checkable”; that’s correct. So I think programming, you know, which is weird to say, that the machine will beat us at most programming tasks before we let it take over roles that have deep empathy, you know, physical presence and social understanding in them. 
    LEE: Yeah. By the way, you know, I fully expect in five years that AI will produce mathematical proofs that are checkable for validity, easily checkable, because they’ll be written in a proof-checking language like Lean or something but will be so complex that no human mathematician can understand them. I expect that to happen.  
    I can imagine in some fields, like cellular biology, we could have the same situation in the future because the molecular pathways, the chemistry, biochemistry of human cells or living cells is as complex as any mathematics, and so it seems possible that we may be in a state where in wet lab, we see, Oh yeah, this actually works, but no one can understand why. 
    BUBECK: Yeah, absolutely. I mean, I think I really agree with Bill’s distinction of the discovery and the delivery, and indeed, the discovery’s when you can check things, and at the end, there is an artifact that you can verify. You know, you can run the protocol in the wet lab and seeproduced what you wanted. So I absolutely agree with that.  
    And in fact, you know, we don’t have to talk five years from now. I don’t know if you know, but just recently, there was a paper that was published on a scientific discovery using o3- mini. So this is really amazing. And, you know, just very quickly, just so people know, it was about this statistical physics model, the frustrated Potts model, which has to do with coloring, and basically, the case of three colors, like, more than two colors was open for a long time, and o3 was able to reduce the case of three colors to two colors.  
    LEE: Yeah. 
    BUBECK: Which is just, like, astounding. And this is not … this is now. This is happening right now. So this is something that I personally didn’t expect it would happen so quickly, and it’s due to those reasoning models.  
    Now, on the delivery side, I would add something more to it for the reason why doctors and, in fact, lawyers and coders will remain for a long time, and it’s because we still don’t understand how those models generalize. Like, at the end of the day, we are not able to tell you when they are confronted with a really new, novel situation, whether they will work or not. 
    Nobody is able to give you that guarantee. And I think until we understand this generalization better, we’re not going to be willing to just let the system in the wild without human supervision. 
    LEE: But don’t human doctors, human specialists … so, for example, a cardiologist sees a patient in a certain way that a nephrologist … 
    BUBECK: Yeah.
    LEE: … or an endocrinologist might not.
    BUBECK: That’s right. But another cardiologist will understand and, kind of, expect a certain level of generalization from their peer. And this, we just don’t have it with AI models. Now, of course, you’re exactly right. That generalization is also hard for humans. Like, if you have a human trained for one task and you put them into another task, then you don’t … you often don’t know.
    LEE: OK. You know, the podcast is focused on what’s happened over the last two years. But now, I’d like one provocative prediction about what you think the world of AI and medicine is going to be at some point in the future. You pick your timeframe. I don’t care if it’s two years or 20 years from now, but, you know, what do you think will be different about AI in medicine in that future than today? 
    BUBECK: Yeah, I think the deployment is going to accelerate soon. Like, we’re really not missing very much. There is this enormous capability overhang. Like, even if progress completely stopped, with current systems, we can do a lot more than what we’re doing right now. So I think this will … this has to be realized, you know, sooner rather than later. 
    And I think it’s probably dependent on these benchmarks and proper evaluation and tying this with regulation. So these are things that take time in human society and for good reason. But now we already are at two years; you know, give it another two years and it should be really …  
    LEE: Will AI prescribe your medicines? Write your prescriptions? 
    BUBECK: I think yes. I think yes. 
    LEE: OK. Bill? 
    GATES: Well, I think the next two years, we’ll have massive pilots, and so the amount of use of the AI, still in a copilot-type mode, you know, we should get millions of patient visits, you know, both in general medicine and in the mental health side, as well. And I think that’s going to build up both the data and the confidence to give the AI some additional autonomy. You know, are you going to let it talk to you at night when you’re panicked about your mental health with some ability to escalate?
    And, you know, I’ve gone so far as to tell politicians with national health systems that if they deploy AI appropriately, that the quality of care, the overload of the doctors, the improvement in the economics will be enough that their voters will be stunned because they just don’t expect this, and, you know, they could be reelectedjust on this one thing of fixing what is a very overloaded and economically challenged health system in these rich countries. 
    You know, my personal role is going to be to make sure that in the poorer countries, there isn’t some lag; in fact, in many cases, that we’ll be more aggressive because, you know, we’re comparing to having no access to doctors at all. And, you know, so I think whether it’s India or Africa, there’ll be lessons that are globally valuable because we need medical intelligence. And, you know, thank god AI is going to provide a lot of that. 
    LEE: Well, on that optimistic note, I think that’s a good way to end. Bill, Seb, really appreciate all of this.  
    I think the most fundamental prediction we made in the book is that AI would actually find its way into the practice of medicine, and I think that that at least has come true, maybe in different ways than we expected, but it’s come true, and I think it’ll only accelerate from here. So thanks again, both of you.  
    GATES: Yeah. Thanks, you guys. 
    BUBECK: Thank you, Peter. Thanks, Bill. 
    LEE: I just always feel such a sense of privilege to have a chance to interact and actually work with people like Bill and Sébastien.   
    With Bill, I’m always amazed at how practically minded he is. He’s really thinking about the nuts and bolts of what AI might be able to do for people, and his thoughts about underserved parts of the world, the idea that we might actually be able to empower people with access to expert medical knowledge, I think is both inspiring and amazing.  
    And then, Seb, Sébastien Bubeck, he’s just absolutely a brilliant mind. He has a really firm grip on the deep mathematics of artificial intelligence and brings that to bear in his research and development work. And where that mathematics takes him isn’t just into the nuts and bolts of algorithms but into philosophical questions about the nature of intelligence.  
    One of the things that Sébastien brought up was the state of evaluation of AI systems. And indeed, he was fairly critical in our conversation. But of course, the world of AI research and development is just moving so fast, and indeed, since we recorded our conversation, OpenAI, in fact, released a new evaluation metric that is directly relevant to medical applications, and that is something called HealthBench. And Microsoft Research also released a new evaluation approach or process called ADeLe.  
    HealthBench and ADeLe are examples of new approaches to evaluating AI models that are less about testing their knowledge and ability to pass multiple-choice exams and instead are evaluation approaches designed to assess how well AI models are able to complete tasks that actually arise every day in typical healthcare or biomedical research settings. These are examples of really important good work that speak to how well AI models work in the real world of healthcare and biomedical research and how well they can collaborate with human beings in those settings. 
    You know, I asked Bill and Seb to make some predictions about the future. You know, my own answer, I expect that we’re going to be able to use AI to change how we diagnose patients, change how we decide treatment options.  
    If you’re a doctor or a nurse and you encounter a patient, you’ll ask questions, do a physical exam, you know, call out for labs just like you do today, but then you’ll be able to engage with AI based on all of that data and just ask, you know, based on all the other people who have gone through the same experience, who have similar data, how were they diagnosed? How were they treated? What were their outcomes? And what does that mean for the patient I have right now? Some people call it the “patients like me” paradigm. And I think that’s going to become real because of AI within our lifetimes. That idea of really grounding the delivery in healthcare and medical practice through data and intelligence, I actually now don’t see any barriers to that future becoming real.  
    I’d like to extend another big thank you to Bill and Sébastien for their time. And to our listeners, as always, it’s a pleasure to have you along for the ride. I hope you’ll join us for our remaining conversations, as well as a second coauthor roundtable with Carey and Zak.  
    Until next time.  
    #how #reshaping #future #healthcare #medical
    How AI is reshaping the future of healthcare and medical research
    Transcript        PETER LEE: “In ‘The Little Black Bag,’ a classic science fiction story, a high-tech doctor’s kit of the future is accidentally transported back to the 1950s, into the shaky hands of a washed-up, alcoholic doctor. The ultimate medical tool, it redeems the doctor wielding it, allowing him to practice gratifyingly heroic medicine. … The tale ends badly for the doctor and his treacherous assistant, but it offered a picture of how advanced technology could transform medicine—powerful when it was written nearly 75 years ago and still so today. What would be the Al equivalent of that little black bag? At this moment when new capabilities are emerging, how do we imagine them into medicine?”           This is The AI Revolution in Medicine, Revisited. I’m your host, Peter Lee.    Shortly after OpenAI’s GPT-4 was publicly released, Carey Goldberg, Dr. Zak Kohane, and I published The AI Revolution in Medicine to help educate the world of healthcare and medical research about the transformative impact this new generative AI technology could have. But because we wrote the book when GPT-4 was still a secret, we had to speculate. Now, two years later, what did we get right, and what did we get wrong?     In this series, we’ll talk to clinicians, patients, hospital administrators, and others to understand the reality of AI in the field and where we go from here.  The book passage I read at the top is from “Chapter 10: The Big Black Bag.”  In imagining AI in medicine, Carey, Zak, and I included in our book two fictional accounts. In the first, a medical resident consults GPT-4 on her personal phone as the patient in front of her crashes. Within seconds, it offers an alternate response based on recent literature. In the second account, a 90-year-old woman with several chronic conditions is living independently and receiving near-constant medical support from an AI aide.    In our conversations with the guests we’ve spoken to so far, we’ve caught a glimpse of these predicted futures, seeing how clinicians and patients are actually using AI today and how developers are leveraging the technology in the healthcare products and services they’re creating. In fact, that first fictional account isn’t so fictional after all, as most of the doctors in the real world actually appear to be using AI at least occasionally—and sometimes much more than occasionally—to help in their daily clinical work. And as for the second fictional account, which is more of a science fiction account, it seems we are indeed on the verge of a new way of delivering and receiving healthcare, though the future is still very much open.  As we continue to examine the current state of AI in healthcare and its potential to transform the field, I’m pleased to welcome Bill Gates and Sébastien Bubeck.   Bill may be best known as the co-founder of Microsoft, having created the company with his childhood friend Paul Allen in 1975. He’s now the founder of Breakthrough Energy, which aims to advance clean energy innovation, and TerraPower, a company developing groundbreaking nuclear energy and science technologies. He also chairs the world’s largest philanthropic organization, the Gates Foundation, and focuses on solving a variety of health challenges around the globe and here at home.  Sébastien is a research lead at OpenAI. He was previously a distinguished scientist, vice president of AI, and a colleague of mine here at Microsoft, where his work included spearheading the development of the family of small language models known as Phi. While at Microsoft, he also coauthored the discussion-provoking 2023 paper “Sparks of Artificial General Intelligence,” which presented the results of early experiments with GPT-4 conducted by a small team from Microsoft Research.      Here’s my conversation with Bill Gates and Sébastien Bubeck.  LEE: Bill, welcome.  BILL GATES: Thank you.  LEE: Seb …  SÉBASTIEN BUBECK: Yeah. Hi, hi, Peter. Nice to be here.  LEE: You know, one of the things that I’ve been doing just to get the conversation warmed up is to talk about origin stories, and what I mean about origin stories is, you know, what was the first contact that you had with large language models or the concept of generative AI that convinced you or made you think that something really important was happening?  And so, Bill, I think I’ve heard the story about, you know, the time when the OpenAI folks—Sam Altman, Greg Brockman, and others—showed you something, but could we hear from you what those early encounters were like and what was going through your mind?   GATES: Well, I’d been visiting OpenAI soon after it was created to see things like GPT-2 and to see the little arm they had that was trying to match human manipulation and, you know, looking at their games like Dota that they were trying to get as good as human play. And honestly, I didn’t think the language model stuff they were doing, even when they got to GPT-3, would show the ability to learn, you know, in the same sense that a human reads a biology book and is able to take that knowledge and access it not only to pass a test but also to create new medicines.  And so my challenge to them was that if their LLM could get a five on the advanced placement biology test, then I would say, OK, it took biologic knowledge and encoded it in an accessible way and that I didn’t expect them to do that very quickly but it would be profound.   And it was only about six months after I challenged them to do that, that an early version of GPT-4 they brought up to a dinner at my house, and in fact, it answered most of the questions that night very well. The one it got totally wrong, we were … because it was so good, we kept thinking, Oh, we must be wrong. It turned out it was a math weaknessthat, you know, we later understood that that was an area of, weirdly, of incredible weakness of those early models. But, you know, that was when I realized, OK, the age of cheap intelligence was at its beginning.  LEE: Yeah. So I guess it seems like you had something similar to me in that my first encounters, I actually harbored some skepticism. Is it fair to say you were skeptical before that?  GATES: Well, the idea that we’ve figured out how to encode and access knowledge in this very deep sense without even understanding the nature of the encoding, …  LEE: Right.   GATES: … that is a bit weird.   LEE: Yeah.  GATES: We have an algorithm that creates the computation, but even say, OK, where is the president’s birthday stored in there? Where is this fact stored in there? The fact that even now when we’re playing around, getting a little bit more sense of it, it’s opaque to us what the semantic encoding is, it’s, kind of, amazing to me. I thought the invention of knowledge storage would be an explicit way of encoding knowledge, not an implicit statistical training.  LEE: Yeah, yeah. All right. So, Seb, you know, on this same topic, you know, I got—as we say at Microsoft—I got pulled into the tent.  BUBECK: Yes.   LEE: Because this was a very secret project. And then, um, I had the opportunity to select a small number of researchers in MSRto join and start investigating this thing seriously. And the first person I pulled in was you.  BUBECK: Yeah.  LEE: And so what were your first encounters? Because I actually don’t remember what happened then.  BUBECK: Oh, I remember it very well.My first encounter with GPT-4 was in a meeting with the two of you, actually. But my kind of first contact, the first moment where I realized that something was happening with generative AI, was before that. And I agree with Bill that I also wasn’t too impressed by GPT-3.  I though that it was kind of, you know, very naturally mimicking the web, sort of parroting what was written there in a nice way. Still in a way which seemed very impressive. But it wasn’t really intelligent in any way. But shortly after GPT-3, there was a model before GPT-4 that really shocked me, and this was the first image generation model, DALL-E 1.  So that was in 2021. And I will forever remember the press release of OpenAI where they had this prompt of an avocado chair and then you had this image of the avocado chair.And what really shocked me is that clearly the model kind of “understood” what is a chair, what is an avocado, and was able to merge those concepts.  So this was really, to me, the first moment where I saw some understanding in those models.   LEE: So this was, just to get the timing right, that was before I pulled you into the tent.  BUBECK: That was before. That was like a year before.  LEE: Right.   BUBECK: And now I will tell you how, you know, we went from that moment to the meeting with the two of you and GPT-4.  So once I saw this kind of understanding, I thought, OK, fine. It understands concept, but it’s still not able to reason. It cannot—as, you know, Bill was saying—it cannot learn from your document. It cannot reason.   So I set out to try to prove that. You know, this is what I was in the business of at the time, trying to prove things in mathematics. So I was trying to prove that basically autoregressive transformers could never reason. So I was trying to prove this. And after a year of work, I had something reasonable to show. And so I had the meeting with the two of you, and I had this example where I wanted to say, there is no way that an LLM is going to be able to do x.  And then as soon as I … I don’t know if you remember, Bill. But as soon as I said that, you said, oh, but wait a second. I had, you know, the OpenAI crew at my house recently, and they showed me a new model. Why don’t we ask this new model this question?   LEE: Yeah. BUBECK: And we did, and it solved it on the spot. And that really, honestly, just changed my life. Like, you know, I had been working for a year trying to say that this was impossible. And just right there, it was shown to be possible.   LEE:One of the very first things I got interested in—because I was really thinking a lot about healthcare—was healthcare and medicine.  And I don’t know if the two of you remember, but I ended up doing a lot of tests. I ran through, you know, step one and step two of the US Medical Licensing Exam. Did a whole bunch of other things. I wrote this big report. It was, you know, I can’t remember … a couple hundred pages.   And I needed to share this with someone. I didn’t … there weren’t too many people I could share it with. So I sent, I think, a copy to you, Bill. Sent a copy to you, Seb.   I hardly slept for about a week putting that report together. And, yeah, and I kept working on it. But I was far from alone. I think everyone who was in the tent, so to speak, in those early days was going through something pretty similar. All right. So I think … of course, a lot of what I put in the report also ended up being examples that made it into the book.  But the main purpose of this conversation isn’t to reminisce aboutor indulge in those reminiscences but to talk about what’s happening in healthcare and medicine. And, you know, as I said, we wrote this book. We did it very, very quickly. Seb, you helped. Bill, you know, you provided a review and some endorsements.  But, you know, honestly, we didn’t know what we were talking about because no one had access to this thing. And so we just made a bunch of guesses. So really, the whole thing I wanted to probe with the two of you is, now with two years of experience out in the world, what, you know, what do we think is happening today?  You know, is AI actually having an impact, positive or negative, on healthcare and medicine? And what do we now think is going to happen in the next two years, five years, or 10 years? And so I realize it’s a little bit too abstract to just ask it that way. So let me just try to narrow the discussion and guide us a little bit.   Um, the kind of administrative and clerical work, paperwork, around healthcare—and we made a lot of guesses about that—that appears to be going well, but, you know, Bill, I know we’ve discussed that sometimes that you think there ought to be a lot more going on. Do you have a viewpoint on how AI is actually finding its way into reducing paperwork?  GATES: Well, I’m stunned … I don’t think there should be a patient-doctor meeting where the AI is not sitting in and both transcribing, offering to help with the paperwork, and even making suggestions, although the doctor will be the one, you know, who makes the final decision about the diagnosis and whatever prescription gets done.   It’s so helpful. You know, when that patient goes home and their, you know, son who wants to understand what happened has some questions, that AI should be available to continue that conversation. And the way you can improve that experience and streamline things and, you know, involve the people who advise you. I don’t understand why that’s not more adopted, because there you still have the human in the loop making that final decision.  But even for, like, follow-up calls to make sure the patient did things, to understand if they have concerns and knowing when to escalate back to the doctor, the benefit is incredible. And, you know, that thing is ready for prime time. That paradigm is ready for prime time, in my view.  LEE: Yeah, there are some good products, but it seems like the number one use right now—and we kind of got this from some of the previous guests in previous episodes—is the use of AI just to respond to emails from patients.Does that make sense to you?  BUBECK: Yeah. So maybe I want to second what Bill was saying but maybe take a step back first. You know, two years ago, like, the concept of clinical scribes, which is one of the things that we’re talking about right now, it would have sounded, in fact, it sounded two years ago, borderline dangerous. Because everybody was worried about hallucinations. What happened if you have this AI listening in and then it transcribes, you know, something wrong?  Now, two years later, I think it’s mostly working. And in fact, it is not yet, you know, fully adopted. You’re right. But it is in production. It is used, you know, in many, many places. So this rate of progress is astounding because it wasn’t obvious that we would be able to overcome those obstacles of hallucination. It’s not to say that hallucinations are fully solved. In the case of the closed system, they are.   Now, I think more generally what’s going on in the background is that there is something that we, that certainly I, underestimated, which is this management overhead. So I think the reason why this is not adopted everywhere is really a training and teaching aspect. People need to be taught, like, those systems, how to interact with them.  And one example that I really like, a study that recently appeared where they tried to use ChatGPT for diagnosis and they were comparing doctors without and with ChatGPT. And the amazing thing … so this was a set of cases where the accuracy of the doctors alone was around 75%. ChatGPT alone was 90%. So that’s already kind of mind blowing. But then the kicker is that doctors with ChatGPT was 80%.   Intelligence alone is not enough. It’s also how it’s presented, how you interact with it. And ChatGPT, it’s an amazing tool. Obviously, I absolutely love it. But it’s not … you don’t want a doctor to have to type in, you know, prompts and use it that way.  It should be, as Bill was saying, kind of running continuously in the background, sending you notifications. And you have to be really careful of the rate at which those notifications are being sent. Because if they are too frequent, then the doctor will learn to ignore them. So you have to … all of those things matter, in fact, at least as much as the level of intelligence of the machine.  LEE: One of the things I think about, Bill, in that scenario that you described, doctors do some thinking about the patient when they write the note. So, you know, I’m always a little uncertain whether it’s actually … you know, you wouldn’t necessarily want to fully automate this, I don’t think. Or at least there needs to be some prompt to the doctor to make sure that the doctor puts some thought into what happened in the encounter with the patient. Does that make sense to you at all?  GATES: At this stage, you know, I’d still put the onus on the doctor to write the conclusions and the summary and not delegate that.  The tradeoffs you make a little bit are somewhat dependent on the situation you’re in. If you’re in Africa, So, yes, the doctor’s still going to have to do a lot of work, but just the quality of letting the patient and the people around them interact and ask questions and have things explained, that alone is such a quality improvement. It’s mind blowing.   LEE: So since you mentioned, you know, Africa—and, of course, this touches on the mission and some of the priorities of the Gates Foundation and this idea of democratization of access to expert medical care—what’s the most interesting stuff going on right now? Are there people and organizations or technologies that are impressing you or that you’re tracking?  GATES: Yeah. So the Gates Foundation has given out a lot of grants to people in Africa doing education, agriculture but more healthcare examples than anything. And the way these things start off, they often start out either being patient-centric in a narrow situation, like, OK, I’m a pregnant woman; talk to me. Or, I have infectious disease symptoms; talk to me. Or they’re connected to a health worker where they’re helping that worker get their job done. And we have lots of pilots out, you know, in both of those cases.   The dream would be eventually to have the thing the patient consults be so broad that it’s like having a doctor available who understands the local things.   LEE: Right.   GATES: We’re not there yet. But over the next two or three years, you know, particularly given the worsening financial constraints against African health systems, where the withdrawal of money has been dramatic, you know, figuring out how to take this—what I sometimes call “free intelligence”—and build a quality health system around that, we will have to be more radical in low-income countries than any rich country is ever going to be.   LEE: Also, there’s maybe a different regulatory environment, so some of those things maybe are easier? Because right now, I think the world hasn’t figured out how to and whether to regulate, let’s say, an AI that might give a medical diagnosis or write a prescription for a medication.  BUBECK: Yeah. I think one issue with this, and it’s also slowing down the deployment of AI in healthcare more generally, is a lack of proper benchmark. Because, you know, you were mentioning the USMLE, for example. That’s a great test to test human beings and their knowledge of healthcare and medicine. But it’s not a great test to give to an AI.  It’s not asking the right questions. So finding what are the right questions to test whether an AI system is ready to give diagnosis in a constrained setting, that’s a very, very important direction, which to my surprise, is not yet accelerating at the rate that I was hoping for.  LEE: OK, so that gives me an excuse to get more now into the core AI tech because something I’ve discussed with both of you is this issue of what are the right tests. And you both know the very first test I give to any new spin of an LLM is I present a patient, the results—a mythical patient—the results of my physical exam, my mythical physical exam. Maybe some results of some initial labs. And then I present or propose a differential diagnosis. And if you’re not in medicine, a differential diagnosis you can just think of as a prioritized list of the possible diagnoses that fit with all that data. And in that proposed differential, I always intentionally make two mistakes.  I make a textbook technical error in one of the possible elements of the differential diagnosis, and I have an error of omission. And, you know, I just want to know, does the LLM understand what I’m talking about? And all the good ones out there do now. But then I want to know, can it spot the errors? And then most importantly, is it willing to tell me I’m wrong, that I’ve made a mistake?   That last piece seems really hard for AI today. And so let me ask you first, Seb, because at the time of this taping, of course, there was a new spin of GPT-4o last week that became overly sycophantic. In other words, it was actually prone in that test of mine not only to not tell me I’m wrong, but it actually praised me for the creativity of my differential.What’s up with that?  BUBECK: Yeah, I guess it’s a testament to the fact that training those models is still more of an art than a science. So it’s a difficult job. Just to be clear with the audience, we have rolled back thatversion of GPT-4o, so now we don’t have the sycophant version out there.  Yeah, no, it’s a really difficult question. It has to do … as you said, it’s very technical. It has to do with the post-training and how, like, where do you nudge the model? So, you know, there is this very classical by now technique called RLHF, where you push the model in the direction of a certain reward model. So the reward model is just telling the model, you know, what behavior is good, what behavior is bad.  But this reward model is itself an LLM, and, you know, Bill was saying at the very beginning of the conversation that we don’t really understand how those LLMs deal with concepts like, you know, where is the capital of France located? Things like that. It is the same thing for this reward model. We don’t know why it says that it prefers one output to another, and whether this is correlated with some sycophancy is, you know, something that we discovered basically just now. That if you push too hard in optimization on this reward model, you will get a sycophant model.  So it’s kind of … what I’m trying to say is we became too good at what we were doing, and we ended up, in fact, in a trap of the reward model.  LEE: I mean, you do want … it’s a difficult balance because you do want models to follow your desires and …  BUBECK: It’s a very difficult, very difficult balance.  LEE: So this brings up then the following question for me, which is the extent to which we think we’ll need to have specially trained models for things. So let me start with you, Bill. Do you have a point of view on whether we will need to, you know, quote-unquote take AI models to med school? Have them specially trained? Like, if you were going to deploy something to give medical care in underserved parts of the world, do we need to do something special to create those models?  GATES: We certainly need to teach them the African languages and the unique dialects so that the multimedia interactions are very high quality. We certainly need to teach them the disease prevalence and unique disease patterns like, you know, neglected tropical diseases and malaria. So we need to gather a set of facts that somebody trying to go for a US customer base, you know, wouldn’t necessarily have that in there.  Those two things are actually very straightforward because the additional training time is small. I’d say for the next few years, we’ll also need to do reinforcement learning about the context of being a doctor and how important certain behaviors are. Humans learn over the course of their life to some degree that, I’m in a different context and the way I behave in terms of being willing to criticize or be nice, you know, how important is it? Who’s here? What’s my relationship to them?   Right now, these machines don’t have that broad social experience. And so if you know it’s going to be used for health things, a lot of reinforcement learning of the very best humans in that context would still be valuable. Eventually, the models will, having read all the literature of the world about good doctors, bad doctors, it’ll understand as soon as you say, “I want you to be a doctor diagnosing somebody.” All of the implicit reinforcement that fits that situation, you know, will be there. LEE: Yeah. GATES: And so I hope three years from now, we don’t have to do that reinforcement learning. But today, for any medical context, you would want a lot of data to reinforce tone, willingness to say things when, you know, there might be something significant at stake.  LEE: Yeah. So, you know, something Bill said, kind of, reminds me of another thing that I think we missed, which is, the context also … and the specialization also pertains to different, I guess, what we still call “modes,” although I don’t know if the idea of multimodal is the same as it was two years ago. But, you know, what do you make of all of the hubbub around—in fact, within Microsoft Research, this is a big deal, but I think we’re far from alone—you know, medical images and vision, video, proteins and molecules, cell, you know, cellular data and so on.  BUBECK: Yeah. OK. So there is a lot to say to everything … to the last, you know, couple of minutes. Maybe on the specialization aspect, you know, I think there is, hiding behind this, a really fundamental scientific question of whether eventually we have a singular AGIthat kind of knows everything and you can just put, you know, explain your own context and it will just get it and understand everything.  That’s one vision. I have to say, I don’t particularly believe in this vision. In fact, we humans are not like that at all. I think, hopefully, we are general intelligences, yet we have to specialize a lot. And, you know, I did myself a lot of RL, reinforcement learning, on mathematics. Like, that’s what I did, you know, spent a lot of time doing that. And I didn’t improve on other aspects. You know, in fact, I probably degraded in other aspects.So it’s … I think it’s an important example to have in mind.  LEE: I think I might disagree with you on that, though, because, like, doesn’t a model have to see both good science and bad science in order to be able to gain the ability to discern between the two?  BUBECK: Yeah, no, that absolutely. I think there is value in seeing the generality, in having a very broad base. But then you, kind of, specialize on verticals. And this is where also, you know, open-weights model, which we haven’t talked about yet, are really important because they allow you to provide this broad base to everyone. And then you can specialize on top of it.  LEE: So we have about three hours of stuff to talk about, but our time is actually running low. BUBECK: Yes, yes, yes.   LEE: So I think I want … there’s a more provocative question. It’s almost a silly question, but I need to ask it of the two of you, which is, is there a future, you know, where AI replaces doctors or replaces, you know, medical specialties that we have today? So what does the world look like, say, five years from now?  GATES: Well, it’s important to distinguish healthcare discovery activity from healthcare delivery activity. We focused mostly on delivery. I think it’s very much within the realm of possibility that the AI is not only accelerating healthcare discovery but substituting for a lot of the roles of, you know, I’m an organic chemist, or I run various types of assays. I can see those, which are, you know, testable-output-type jobs but with still very high value, I can see, you know, some replacement in those areas before the doctor.   The doctor, still understanding the human condition and long-term dialogues, you know, they’ve had a lifetime of reinforcement of that, particularly when you get into areas like mental health. So I wouldn’t say in five years, either people will choose to adopt it, but it will be profound that there’ll be this nearly free intelligence that can do follow-up, that can help you, you know, make sure you went through different possibilities.  And so I’d say, yes, we’ll have doctors, but I’d say healthcare will be massively transformed in its quality and in efficiency by AI in that time period.  LEE: Is there a comparison, useful comparison, say, between doctors and, say, programmers, computer programmers, or doctors and, I don’t know, lawyers?  GATES: Programming is another one that has, kind of, a mathematical correctness to it, you know, and so the objective function that you’re trying to reinforce to, as soon as you can understand the state machines, you can have something that’s “checkable”; that’s correct. So I think programming, you know, which is weird to say, that the machine will beat us at most programming tasks before we let it take over roles that have deep empathy, you know, physical presence and social understanding in them.  LEE: Yeah. By the way, you know, I fully expect in five years that AI will produce mathematical proofs that are checkable for validity, easily checkable, because they’ll be written in a proof-checking language like Lean or something but will be so complex that no human mathematician can understand them. I expect that to happen.   I can imagine in some fields, like cellular biology, we could have the same situation in the future because the molecular pathways, the chemistry, biochemistry of human cells or living cells is as complex as any mathematics, and so it seems possible that we may be in a state where in wet lab, we see, Oh yeah, this actually works, but no one can understand why.  BUBECK: Yeah, absolutely. I mean, I think I really agree with Bill’s distinction of the discovery and the delivery, and indeed, the discovery’s when you can check things, and at the end, there is an artifact that you can verify. You know, you can run the protocol in the wet lab and seeproduced what you wanted. So I absolutely agree with that.   And in fact, you know, we don’t have to talk five years from now. I don’t know if you know, but just recently, there was a paper that was published on a scientific discovery using o3- mini. So this is really amazing. And, you know, just very quickly, just so people know, it was about this statistical physics model, the frustrated Potts model, which has to do with coloring, and basically, the case of three colors, like, more than two colors was open for a long time, and o3 was able to reduce the case of three colors to two colors.   LEE: Yeah.  BUBECK: Which is just, like, astounding. And this is not … this is now. This is happening right now. So this is something that I personally didn’t expect it would happen so quickly, and it’s due to those reasoning models.   Now, on the delivery side, I would add something more to it for the reason why doctors and, in fact, lawyers and coders will remain for a long time, and it’s because we still don’t understand how those models generalize. Like, at the end of the day, we are not able to tell you when they are confronted with a really new, novel situation, whether they will work or not.  Nobody is able to give you that guarantee. And I think until we understand this generalization better, we’re not going to be willing to just let the system in the wild without human supervision.  LEE: But don’t human doctors, human specialists … so, for example, a cardiologist sees a patient in a certain way that a nephrologist …  BUBECK: Yeah. LEE: … or an endocrinologist might not. BUBECK: That’s right. But another cardiologist will understand and, kind of, expect a certain level of generalization from their peer. And this, we just don’t have it with AI models. Now, of course, you’re exactly right. That generalization is also hard for humans. Like, if you have a human trained for one task and you put them into another task, then you don’t … you often don’t know. LEE: OK. You know, the podcast is focused on what’s happened over the last two years. But now, I’d like one provocative prediction about what you think the world of AI and medicine is going to be at some point in the future. You pick your timeframe. I don’t care if it’s two years or 20 years from now, but, you know, what do you think will be different about AI in medicine in that future than today?  BUBECK: Yeah, I think the deployment is going to accelerate soon. Like, we’re really not missing very much. There is this enormous capability overhang. Like, even if progress completely stopped, with current systems, we can do a lot more than what we’re doing right now. So I think this will … this has to be realized, you know, sooner rather than later.  And I think it’s probably dependent on these benchmarks and proper evaluation and tying this with regulation. So these are things that take time in human society and for good reason. But now we already are at two years; you know, give it another two years and it should be really …   LEE: Will AI prescribe your medicines? Write your prescriptions?  BUBECK: I think yes. I think yes.  LEE: OK. Bill?  GATES: Well, I think the next two years, we’ll have massive pilots, and so the amount of use of the AI, still in a copilot-type mode, you know, we should get millions of patient visits, you know, both in general medicine and in the mental health side, as well. And I think that’s going to build up both the data and the confidence to give the AI some additional autonomy. You know, are you going to let it talk to you at night when you’re panicked about your mental health with some ability to escalate? And, you know, I’ve gone so far as to tell politicians with national health systems that if they deploy AI appropriately, that the quality of care, the overload of the doctors, the improvement in the economics will be enough that their voters will be stunned because they just don’t expect this, and, you know, they could be reelectedjust on this one thing of fixing what is a very overloaded and economically challenged health system in these rich countries.  You know, my personal role is going to be to make sure that in the poorer countries, there isn’t some lag; in fact, in many cases, that we’ll be more aggressive because, you know, we’re comparing to having no access to doctors at all. And, you know, so I think whether it’s India or Africa, there’ll be lessons that are globally valuable because we need medical intelligence. And, you know, thank god AI is going to provide a lot of that.  LEE: Well, on that optimistic note, I think that’s a good way to end. Bill, Seb, really appreciate all of this.   I think the most fundamental prediction we made in the book is that AI would actually find its way into the practice of medicine, and I think that that at least has come true, maybe in different ways than we expected, but it’s come true, and I think it’ll only accelerate from here. So thanks again, both of you.   GATES: Yeah. Thanks, you guys.  BUBECK: Thank you, Peter. Thanks, Bill.  LEE: I just always feel such a sense of privilege to have a chance to interact and actually work with people like Bill and Sébastien.    With Bill, I’m always amazed at how practically minded he is. He’s really thinking about the nuts and bolts of what AI might be able to do for people, and his thoughts about underserved parts of the world, the idea that we might actually be able to empower people with access to expert medical knowledge, I think is both inspiring and amazing.   And then, Seb, Sébastien Bubeck, he’s just absolutely a brilliant mind. He has a really firm grip on the deep mathematics of artificial intelligence and brings that to bear in his research and development work. And where that mathematics takes him isn’t just into the nuts and bolts of algorithms but into philosophical questions about the nature of intelligence.   One of the things that Sébastien brought up was the state of evaluation of AI systems. And indeed, he was fairly critical in our conversation. But of course, the world of AI research and development is just moving so fast, and indeed, since we recorded our conversation, OpenAI, in fact, released a new evaluation metric that is directly relevant to medical applications, and that is something called HealthBench. And Microsoft Research also released a new evaluation approach or process called ADeLe.   HealthBench and ADeLe are examples of new approaches to evaluating AI models that are less about testing their knowledge and ability to pass multiple-choice exams and instead are evaluation approaches designed to assess how well AI models are able to complete tasks that actually arise every day in typical healthcare or biomedical research settings. These are examples of really important good work that speak to how well AI models work in the real world of healthcare and biomedical research and how well they can collaborate with human beings in those settings.  You know, I asked Bill and Seb to make some predictions about the future. You know, my own answer, I expect that we’re going to be able to use AI to change how we diagnose patients, change how we decide treatment options.   If you’re a doctor or a nurse and you encounter a patient, you’ll ask questions, do a physical exam, you know, call out for labs just like you do today, but then you’ll be able to engage with AI based on all of that data and just ask, you know, based on all the other people who have gone through the same experience, who have similar data, how were they diagnosed? How were they treated? What were their outcomes? And what does that mean for the patient I have right now? Some people call it the “patients like me” paradigm. And I think that’s going to become real because of AI within our lifetimes. That idea of really grounding the delivery in healthcare and medical practice through data and intelligence, I actually now don’t see any barriers to that future becoming real.   I’d like to extend another big thank you to Bill and Sébastien for their time. And to our listeners, as always, it’s a pleasure to have you along for the ride. I hope you’ll join us for our remaining conversations, as well as a second coauthor roundtable with Carey and Zak.   Until next time.   #how #reshaping #future #healthcare #medical
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    How AI is reshaping the future of healthcare and medical research
    Transcript [MUSIC]      [BOOK PASSAGE]   PETER LEE: “In ‘The Little Black Bag,’ a classic science fiction story, a high-tech doctor’s kit of the future is accidentally transported back to the 1950s, into the shaky hands of a washed-up, alcoholic doctor. The ultimate medical tool, it redeems the doctor wielding it, allowing him to practice gratifyingly heroic medicine. … The tale ends badly for the doctor and his treacherous assistant, but it offered a picture of how advanced technology could transform medicine—powerful when it was written nearly 75 years ago and still so today. What would be the Al equivalent of that little black bag? At this moment when new capabilities are emerging, how do we imagine them into medicine?”   [END OF BOOK PASSAGE]     [THEME MUSIC]     This is The AI Revolution in Medicine, Revisited. I’m your host, Peter Lee.    Shortly after OpenAI’s GPT-4 was publicly released, Carey Goldberg, Dr. Zak Kohane, and I published The AI Revolution in Medicine to help educate the world of healthcare and medical research about the transformative impact this new generative AI technology could have. But because we wrote the book when GPT-4 was still a secret, we had to speculate. Now, two years later, what did we get right, and what did we get wrong?     In this series, we’ll talk to clinicians, patients, hospital administrators, and others to understand the reality of AI in the field and where we go from here.   [THEME MUSIC FADES] The book passage I read at the top is from “Chapter 10: The Big Black Bag.”  In imagining AI in medicine, Carey, Zak, and I included in our book two fictional accounts. In the first, a medical resident consults GPT-4 on her personal phone as the patient in front of her crashes. Within seconds, it offers an alternate response based on recent literature. In the second account, a 90-year-old woman with several chronic conditions is living independently and receiving near-constant medical support from an AI aide.    In our conversations with the guests we’ve spoken to so far, we’ve caught a glimpse of these predicted futures, seeing how clinicians and patients are actually using AI today and how developers are leveraging the technology in the healthcare products and services they’re creating. In fact, that first fictional account isn’t so fictional after all, as most of the doctors in the real world actually appear to be using AI at least occasionally—and sometimes much more than occasionally—to help in their daily clinical work. And as for the second fictional account, which is more of a science fiction account, it seems we are indeed on the verge of a new way of delivering and receiving healthcare, though the future is still very much open.  As we continue to examine the current state of AI in healthcare and its potential to transform the field, I’m pleased to welcome Bill Gates and Sébastien Bubeck.   Bill may be best known as the co-founder of Microsoft, having created the company with his childhood friend Paul Allen in 1975. He’s now the founder of Breakthrough Energy, which aims to advance clean energy innovation, and TerraPower, a company developing groundbreaking nuclear energy and science technologies. He also chairs the world’s largest philanthropic organization, the Gates Foundation, and focuses on solving a variety of health challenges around the globe and here at home.  Sébastien is a research lead at OpenAI. He was previously a distinguished scientist, vice president of AI, and a colleague of mine here at Microsoft, where his work included spearheading the development of the family of small language models known as Phi. While at Microsoft, he also coauthored the discussion-provoking 2023 paper “Sparks of Artificial General Intelligence,” which presented the results of early experiments with GPT-4 conducted by a small team from Microsoft Research.    [TRANSITION MUSIC]   Here’s my conversation with Bill Gates and Sébastien Bubeck.  LEE: Bill, welcome.  BILL GATES: Thank you.  LEE: Seb …  SÉBASTIEN BUBECK: Yeah. Hi, hi, Peter. Nice to be here.  LEE: You know, one of the things that I’ve been doing just to get the conversation warmed up is to talk about origin stories, and what I mean about origin stories is, you know, what was the first contact that you had with large language models or the concept of generative AI that convinced you or made you think that something really important was happening?  And so, Bill, I think I’ve heard the story about, you know, the time when the OpenAI folks—Sam Altman, Greg Brockman, and others—showed you something, but could we hear from you what those early encounters were like and what was going through your mind?   GATES: Well, I’d been visiting OpenAI soon after it was created to see things like GPT-2 and to see the little arm they had that was trying to match human manipulation and, you know, looking at their games like Dota that they were trying to get as good as human play. And honestly, I didn’t think the language model stuff they were doing, even when they got to GPT-3, would show the ability to learn, you know, in the same sense that a human reads a biology book and is able to take that knowledge and access it not only to pass a test but also to create new medicines.  And so my challenge to them was that if their LLM could get a five on the advanced placement biology test, then I would say, OK, it took biologic knowledge and encoded it in an accessible way and that I didn’t expect them to do that very quickly but it would be profound.   And it was only about six months after I challenged them to do that, that an early version of GPT-4 they brought up to a dinner at my house, and in fact, it answered most of the questions that night very well. The one it got totally wrong, we were … because it was so good, we kept thinking, Oh, we must be wrong. It turned out it was a math weakness [LAUGHTER] that, you know, we later understood that that was an area of, weirdly, of incredible weakness of those early models. But, you know, that was when I realized, OK, the age of cheap intelligence was at its beginning.  LEE: Yeah. So I guess it seems like you had something similar to me in that my first encounters, I actually harbored some skepticism. Is it fair to say you were skeptical before that?  GATES: Well, the idea that we’ve figured out how to encode and access knowledge in this very deep sense without even understanding the nature of the encoding, …  LEE: Right.   GATES: … that is a bit weird.   LEE: Yeah.  GATES: We have an algorithm that creates the computation, but even say, OK, where is the president’s birthday stored in there? Where is this fact stored in there? The fact that even now when we’re playing around, getting a little bit more sense of it, it’s opaque to us what the semantic encoding is, it’s, kind of, amazing to me. I thought the invention of knowledge storage would be an explicit way of encoding knowledge, not an implicit statistical training.  LEE: Yeah, yeah. All right. So, Seb, you know, on this same topic, you know, I got—as we say at Microsoft—I got pulled into the tent. [LAUGHS]  BUBECK: Yes.   LEE: Because this was a very secret project. And then, um, I had the opportunity to select a small number of researchers in MSR [Microsoft Research] to join and start investigating this thing seriously. And the first person I pulled in was you.  BUBECK: Yeah.  LEE: And so what were your first encounters? Because I actually don’t remember what happened then.  BUBECK: Oh, I remember it very well. [LAUGHS] My first encounter with GPT-4 was in a meeting with the two of you, actually. But my kind of first contact, the first moment where I realized that something was happening with generative AI, was before that. And I agree with Bill that I also wasn’t too impressed by GPT-3.  I though that it was kind of, you know, very naturally mimicking the web, sort of parroting what was written there in a nice way. Still in a way which seemed very impressive. But it wasn’t really intelligent in any way. But shortly after GPT-3, there was a model before GPT-4 that really shocked me, and this was the first image generation model, DALL-E 1.  So that was in 2021. And I will forever remember the press release of OpenAI where they had this prompt of an avocado chair and then you had this image of the avocado chair. [LAUGHTER] And what really shocked me is that clearly the model kind of “understood” what is a chair, what is an avocado, and was able to merge those concepts.  So this was really, to me, the first moment where I saw some understanding in those models.   LEE: So this was, just to get the timing right, that was before I pulled you into the tent.  BUBECK: That was before. That was like a year before.  LEE: Right.   BUBECK: And now I will tell you how, you know, we went from that moment to the meeting with the two of you and GPT-4.  So once I saw this kind of understanding, I thought, OK, fine. It understands concept, but it’s still not able to reason. It cannot—as, you know, Bill was saying—it cannot learn from your document. It cannot reason.   So I set out to try to prove that. You know, this is what I was in the business of at the time, trying to prove things in mathematics. So I was trying to prove that basically autoregressive transformers could never reason. So I was trying to prove this. And after a year of work, I had something reasonable to show. And so I had the meeting with the two of you, and I had this example where I wanted to say, there is no way that an LLM is going to be able to do x.  And then as soon as I … I don’t know if you remember, Bill. But as soon as I said that, you said, oh, but wait a second. I had, you know, the OpenAI crew at my house recently, and they showed me a new model. Why don’t we ask this new model this question?   LEE: Yeah. BUBECK: And we did, and it solved it on the spot. And that really, honestly, just changed my life. Like, you know, I had been working for a year trying to say that this was impossible. And just right there, it was shown to be possible.   LEE: [LAUGHS] One of the very first things I got interested in—because I was really thinking a lot about healthcare—was healthcare and medicine.  And I don’t know if the two of you remember, but I ended up doing a lot of tests. I ran through, you know, step one and step two of the US Medical Licensing Exam. Did a whole bunch of other things. I wrote this big report. It was, you know, I can’t remember … a couple hundred pages.   And I needed to share this with someone. I didn’t … there weren’t too many people I could share it with. So I sent, I think, a copy to you, Bill. Sent a copy to you, Seb.   I hardly slept for about a week putting that report together. And, yeah, and I kept working on it. But I was far from alone. I think everyone who was in the tent, so to speak, in those early days was going through something pretty similar. All right. So I think … of course, a lot of what I put in the report also ended up being examples that made it into the book.  But the main purpose of this conversation isn’t to reminisce about [LAUGHS] or indulge in those reminiscences but to talk about what’s happening in healthcare and medicine. And, you know, as I said, we wrote this book. We did it very, very quickly. Seb, you helped. Bill, you know, you provided a review and some endorsements.  But, you know, honestly, we didn’t know what we were talking about because no one had access to this thing. And so we just made a bunch of guesses. So really, the whole thing I wanted to probe with the two of you is, now with two years of experience out in the world, what, you know, what do we think is happening today?  You know, is AI actually having an impact, positive or negative, on healthcare and medicine? And what do we now think is going to happen in the next two years, five years, or 10 years? And so I realize it’s a little bit too abstract to just ask it that way. So let me just try to narrow the discussion and guide us a little bit.   Um, the kind of administrative and clerical work, paperwork, around healthcare—and we made a lot of guesses about that—that appears to be going well, but, you know, Bill, I know we’ve discussed that sometimes that you think there ought to be a lot more going on. Do you have a viewpoint on how AI is actually finding its way into reducing paperwork?  GATES: Well, I’m stunned … I don’t think there should be a patient-doctor meeting where the AI is not sitting in and both transcribing, offering to help with the paperwork, and even making suggestions, although the doctor will be the one, you know, who makes the final decision about the diagnosis and whatever prescription gets done.   It’s so helpful. You know, when that patient goes home and their, you know, son who wants to understand what happened has some questions, that AI should be available to continue that conversation. And the way you can improve that experience and streamline things and, you know, involve the people who advise you. I don’t understand why that’s not more adopted, because there you still have the human in the loop making that final decision.  But even for, like, follow-up calls to make sure the patient did things, to understand if they have concerns and knowing when to escalate back to the doctor, the benefit is incredible. And, you know, that thing is ready for prime time. That paradigm is ready for prime time, in my view.  LEE: Yeah, there are some good products, but it seems like the number one use right now—and we kind of got this from some of the previous guests in previous episodes—is the use of AI just to respond to emails from patients. [LAUGHTER] Does that make sense to you?  BUBECK: Yeah. So maybe I want to second what Bill was saying but maybe take a step back first. You know, two years ago, like, the concept of clinical scribes, which is one of the things that we’re talking about right now, it would have sounded, in fact, it sounded two years ago, borderline dangerous. Because everybody was worried about hallucinations. What happened if you have this AI listening in and then it transcribes, you know, something wrong?  Now, two years later, I think it’s mostly working. And in fact, it is not yet, you know, fully adopted. You’re right. But it is in production. It is used, you know, in many, many places. So this rate of progress is astounding because it wasn’t obvious that we would be able to overcome those obstacles of hallucination. It’s not to say that hallucinations are fully solved. In the case of the closed system, they are.   Now, I think more generally what’s going on in the background is that there is something that we, that certainly I, underestimated, which is this management overhead. So I think the reason why this is not adopted everywhere is really a training and teaching aspect. People need to be taught, like, those systems, how to interact with them.  And one example that I really like, a study that recently appeared where they tried to use ChatGPT for diagnosis and they were comparing doctors without and with ChatGPT (opens in new tab). And the amazing thing … so this was a set of cases where the accuracy of the doctors alone was around 75%. ChatGPT alone was 90%. So that’s already kind of mind blowing. But then the kicker is that doctors with ChatGPT was 80%.   Intelligence alone is not enough. It’s also how it’s presented, how you interact with it. And ChatGPT, it’s an amazing tool. Obviously, I absolutely love it. But it’s not … you don’t want a doctor to have to type in, you know, prompts and use it that way.  It should be, as Bill was saying, kind of running continuously in the background, sending you notifications. And you have to be really careful of the rate at which those notifications are being sent. Because if they are too frequent, then the doctor will learn to ignore them. So you have to … all of those things matter, in fact, at least as much as the level of intelligence of the machine.  LEE: One of the things I think about, Bill, in that scenario that you described, doctors do some thinking about the patient when they write the note. So, you know, I’m always a little uncertain whether it’s actually … you know, you wouldn’t necessarily want to fully automate this, I don’t think. Or at least there needs to be some prompt to the doctor to make sure that the doctor puts some thought into what happened in the encounter with the patient. Does that make sense to you at all?  GATES: At this stage, you know, I’d still put the onus on the doctor to write the conclusions and the summary and not delegate that.  The tradeoffs you make a little bit are somewhat dependent on the situation you’re in. If you’re in Africa, So, yes, the doctor’s still going to have to do a lot of work, but just the quality of letting the patient and the people around them interact and ask questions and have things explained, that alone is such a quality improvement. It’s mind blowing.   LEE: So since you mentioned, you know, Africa—and, of course, this touches on the mission and some of the priorities of the Gates Foundation and this idea of democratization of access to expert medical care—what’s the most interesting stuff going on right now? Are there people and organizations or technologies that are impressing you or that you’re tracking?  GATES: Yeah. So the Gates Foundation has given out a lot of grants to people in Africa doing education, agriculture but more healthcare examples than anything. And the way these things start off, they often start out either being patient-centric in a narrow situation, like, OK, I’m a pregnant woman; talk to me. Or, I have infectious disease symptoms; talk to me. Or they’re connected to a health worker where they’re helping that worker get their job done. And we have lots of pilots out, you know, in both of those cases.   The dream would be eventually to have the thing the patient consults be so broad that it’s like having a doctor available who understands the local things.   LEE: Right.   GATES: We’re not there yet. But over the next two or three years, you know, particularly given the worsening financial constraints against African health systems, where the withdrawal of money has been dramatic, you know, figuring out how to take this—what I sometimes call “free intelligence”—and build a quality health system around that, we will have to be more radical in low-income countries than any rich country is ever going to be.   LEE: Also, there’s maybe a different regulatory environment, so some of those things maybe are easier? Because right now, I think the world hasn’t figured out how to and whether to regulate, let’s say, an AI that might give a medical diagnosis or write a prescription for a medication.  BUBECK: Yeah. I think one issue with this, and it’s also slowing down the deployment of AI in healthcare more generally, is a lack of proper benchmark. Because, you know, you were mentioning the USMLE [United States Medical Licensing Examination], for example. That’s a great test to test human beings and their knowledge of healthcare and medicine. But it’s not a great test to give to an AI.  It’s not asking the right questions. So finding what are the right questions to test whether an AI system is ready to give diagnosis in a constrained setting, that’s a very, very important direction, which to my surprise, is not yet accelerating at the rate that I was hoping for.  LEE: OK, so that gives me an excuse to get more now into the core AI tech because something I’ve discussed with both of you is this issue of what are the right tests. And you both know the very first test I give to any new spin of an LLM is I present a patient, the results—a mythical patient—the results of my physical exam, my mythical physical exam. Maybe some results of some initial labs. And then I present or propose a differential diagnosis. And if you’re not in medicine, a differential diagnosis you can just think of as a prioritized list of the possible diagnoses that fit with all that data. And in that proposed differential, I always intentionally make two mistakes.  I make a textbook technical error in one of the possible elements of the differential diagnosis, and I have an error of omission. And, you know, I just want to know, does the LLM understand what I’m talking about? And all the good ones out there do now. But then I want to know, can it spot the errors? And then most importantly, is it willing to tell me I’m wrong, that I’ve made a mistake?   That last piece seems really hard for AI today. And so let me ask you first, Seb, because at the time of this taping, of course, there was a new spin of GPT-4o last week that became overly sycophantic. In other words, it was actually prone in that test of mine not only to not tell me I’m wrong, but it actually praised me for the creativity of my differential. [LAUGHTER] What’s up with that?  BUBECK: Yeah, I guess it’s a testament to the fact that training those models is still more of an art than a science. So it’s a difficult job. Just to be clear with the audience, we have rolled back that [LAUGHS] version of GPT-4o, so now we don’t have the sycophant version out there.  Yeah, no, it’s a really difficult question. It has to do … as you said, it’s very technical. It has to do with the post-training and how, like, where do you nudge the model? So, you know, there is this very classical by now technique called RLHF [reinforcement learning from human feedback], where you push the model in the direction of a certain reward model. So the reward model is just telling the model, you know, what behavior is good, what behavior is bad.  But this reward model is itself an LLM, and, you know, Bill was saying at the very beginning of the conversation that we don’t really understand how those LLMs deal with concepts like, you know, where is the capital of France located? Things like that. It is the same thing for this reward model. We don’t know why it says that it prefers one output to another, and whether this is correlated with some sycophancy is, you know, something that we discovered basically just now. That if you push too hard in optimization on this reward model, you will get a sycophant model.  So it’s kind of … what I’m trying to say is we became too good at what we were doing, and we ended up, in fact, in a trap of the reward model.  LEE: I mean, you do want … it’s a difficult balance because you do want models to follow your desires and …  BUBECK: It’s a very difficult, very difficult balance.  LEE: So this brings up then the following question for me, which is the extent to which we think we’ll need to have specially trained models for things. So let me start with you, Bill. Do you have a point of view on whether we will need to, you know, quote-unquote take AI models to med school? Have them specially trained? Like, if you were going to deploy something to give medical care in underserved parts of the world, do we need to do something special to create those models?  GATES: We certainly need to teach them the African languages and the unique dialects so that the multimedia interactions are very high quality. We certainly need to teach them the disease prevalence and unique disease patterns like, you know, neglected tropical diseases and malaria. So we need to gather a set of facts that somebody trying to go for a US customer base, you know, wouldn’t necessarily have that in there.  Those two things are actually very straightforward because the additional training time is small. I’d say for the next few years, we’ll also need to do reinforcement learning about the context of being a doctor and how important certain behaviors are. Humans learn over the course of their life to some degree that, I’m in a different context and the way I behave in terms of being willing to criticize or be nice, you know, how important is it? Who’s here? What’s my relationship to them?   Right now, these machines don’t have that broad social experience. And so if you know it’s going to be used for health things, a lot of reinforcement learning of the very best humans in that context would still be valuable. Eventually, the models will, having read all the literature of the world about good doctors, bad doctors, it’ll understand as soon as you say, “I want you to be a doctor diagnosing somebody.” All of the implicit reinforcement that fits that situation, you know, will be there. LEE: Yeah. GATES: And so I hope three years from now, we don’t have to do that reinforcement learning. But today, for any medical context, you would want a lot of data to reinforce tone, willingness to say things when, you know, there might be something significant at stake.  LEE: Yeah. So, you know, something Bill said, kind of, reminds me of another thing that I think we missed, which is, the context also … and the specialization also pertains to different, I guess, what we still call “modes,” although I don’t know if the idea of multimodal is the same as it was two years ago. But, you know, what do you make of all of the hubbub around—in fact, within Microsoft Research, this is a big deal, but I think we’re far from alone—you know, medical images and vision, video, proteins and molecules, cell, you know, cellular data and so on.  BUBECK: Yeah. OK. So there is a lot to say to everything … to the last, you know, couple of minutes. Maybe on the specialization aspect, you know, I think there is, hiding behind this, a really fundamental scientific question of whether eventually we have a singular AGI [artificial general intelligence] that kind of knows everything and you can just put, you know, explain your own context and it will just get it and understand everything.  That’s one vision. I have to say, I don’t particularly believe in this vision. In fact, we humans are not like that at all. I think, hopefully, we are general intelligences, yet we have to specialize a lot. And, you know, I did myself a lot of RL, reinforcement learning, on mathematics. Like, that’s what I did, you know, spent a lot of time doing that. And I didn’t improve on other aspects. You know, in fact, I probably degraded in other aspects. [LAUGHTER] So it’s … I think it’s an important example to have in mind.  LEE: I think I might disagree with you on that, though, because, like, doesn’t a model have to see both good science and bad science in order to be able to gain the ability to discern between the two?  BUBECK: Yeah, no, that absolutely. I think there is value in seeing the generality, in having a very broad base. But then you, kind of, specialize on verticals. And this is where also, you know, open-weights model, which we haven’t talked about yet, are really important because they allow you to provide this broad base to everyone. And then you can specialize on top of it.  LEE: So we have about three hours of stuff to talk about, but our time is actually running low. BUBECK: Yes, yes, yes.   LEE: So I think I want … there’s a more provocative question. It’s almost a silly question, but I need to ask it of the two of you, which is, is there a future, you know, where AI replaces doctors or replaces, you know, medical specialties that we have today? So what does the world look like, say, five years from now?  GATES: Well, it’s important to distinguish healthcare discovery activity from healthcare delivery activity. We focused mostly on delivery. I think it’s very much within the realm of possibility that the AI is not only accelerating healthcare discovery but substituting for a lot of the roles of, you know, I’m an organic chemist, or I run various types of assays. I can see those, which are, you know, testable-output-type jobs but with still very high value, I can see, you know, some replacement in those areas before the doctor.   The doctor, still understanding the human condition and long-term dialogues, you know, they’ve had a lifetime of reinforcement of that, particularly when you get into areas like mental health. So I wouldn’t say in five years, either people will choose to adopt it, but it will be profound that there’ll be this nearly free intelligence that can do follow-up, that can help you, you know, make sure you went through different possibilities.  And so I’d say, yes, we’ll have doctors, but I’d say healthcare will be massively transformed in its quality and in efficiency by AI in that time period.  LEE: Is there a comparison, useful comparison, say, between doctors and, say, programmers, computer programmers, or doctors and, I don’t know, lawyers?  GATES: Programming is another one that has, kind of, a mathematical correctness to it, you know, and so the objective function that you’re trying to reinforce to, as soon as you can understand the state machines, you can have something that’s “checkable”; that’s correct. So I think programming, you know, which is weird to say, that the machine will beat us at most programming tasks before we let it take over roles that have deep empathy, you know, physical presence and social understanding in them.  LEE: Yeah. By the way, you know, I fully expect in five years that AI will produce mathematical proofs that are checkable for validity, easily checkable, because they’ll be written in a proof-checking language like Lean or something but will be so complex that no human mathematician can understand them. I expect that to happen.   I can imagine in some fields, like cellular biology, we could have the same situation in the future because the molecular pathways, the chemistry, biochemistry of human cells or living cells is as complex as any mathematics, and so it seems possible that we may be in a state where in wet lab, we see, Oh yeah, this actually works, but no one can understand why.  BUBECK: Yeah, absolutely. I mean, I think I really agree with Bill’s distinction of the discovery and the delivery, and indeed, the discovery’s when you can check things, and at the end, there is an artifact that you can verify. You know, you can run the protocol in the wet lab and see [if you have] produced what you wanted. So I absolutely agree with that.   And in fact, you know, we don’t have to talk five years from now. I don’t know if you know, but just recently, there was a paper that was published on a scientific discovery using o3- mini (opens in new tab). So this is really amazing. And, you know, just very quickly, just so people know, it was about this statistical physics model, the frustrated Potts model, which has to do with coloring, and basically, the case of three colors, like, more than two colors was open for a long time, and o3 was able to reduce the case of three colors to two colors.   LEE: Yeah.  BUBECK: Which is just, like, astounding. And this is not … this is now. This is happening right now. So this is something that I personally didn’t expect it would happen so quickly, and it’s due to those reasoning models.   Now, on the delivery side, I would add something more to it for the reason why doctors and, in fact, lawyers and coders will remain for a long time, and it’s because we still don’t understand how those models generalize. Like, at the end of the day, we are not able to tell you when they are confronted with a really new, novel situation, whether they will work or not.  Nobody is able to give you that guarantee. And I think until we understand this generalization better, we’re not going to be willing to just let the system in the wild without human supervision.  LEE: But don’t human doctors, human specialists … so, for example, a cardiologist sees a patient in a certain way that a nephrologist …  BUBECK: Yeah. LEE: … or an endocrinologist might not. BUBECK: That’s right. But another cardiologist will understand and, kind of, expect a certain level of generalization from their peer. And this, we just don’t have it with AI models. Now, of course, you’re exactly right. That generalization is also hard for humans. Like, if you have a human trained for one task and you put them into another task, then you don’t … you often don’t know. LEE: OK. You know, the podcast is focused on what’s happened over the last two years. But now, I’d like one provocative prediction about what you think the world of AI and medicine is going to be at some point in the future. You pick your timeframe. I don’t care if it’s two years or 20 years from now, but, you know, what do you think will be different about AI in medicine in that future than today?  BUBECK: Yeah, I think the deployment is going to accelerate soon. Like, we’re really not missing very much. There is this enormous capability overhang. Like, even if progress completely stopped, with current systems, we can do a lot more than what we’re doing right now. So I think this will … this has to be realized, you know, sooner rather than later.  And I think it’s probably dependent on these benchmarks and proper evaluation and tying this with regulation. So these are things that take time in human society and for good reason. But now we already are at two years; you know, give it another two years and it should be really …   LEE: Will AI prescribe your medicines? Write your prescriptions?  BUBECK: I think yes. I think yes.  LEE: OK. Bill?  GATES: Well, I think the next two years, we’ll have massive pilots, and so the amount of use of the AI, still in a copilot-type mode, you know, we should get millions of patient visits, you know, both in general medicine and in the mental health side, as well. And I think that’s going to build up both the data and the confidence to give the AI some additional autonomy. You know, are you going to let it talk to you at night when you’re panicked about your mental health with some ability to escalate? And, you know, I’ve gone so far as to tell politicians with national health systems that if they deploy AI appropriately, that the quality of care, the overload of the doctors, the improvement in the economics will be enough that their voters will be stunned because they just don’t expect this, and, you know, they could be reelected [LAUGHTER] just on this one thing of fixing what is a very overloaded and economically challenged health system in these rich countries.  You know, my personal role is going to be to make sure that in the poorer countries, there isn’t some lag; in fact, in many cases, that we’ll be more aggressive because, you know, we’re comparing to having no access to doctors at all. And, you know, so I think whether it’s India or Africa, there’ll be lessons that are globally valuable because we need medical intelligence. And, you know, thank god AI is going to provide a lot of that.  LEE: Well, on that optimistic note, I think that’s a good way to end. Bill, Seb, really appreciate all of this.   I think the most fundamental prediction we made in the book is that AI would actually find its way into the practice of medicine, and I think that that at least has come true, maybe in different ways than we expected, but it’s come true, and I think it’ll only accelerate from here. So thanks again, both of you.  [TRANSITION MUSIC]  GATES: Yeah. Thanks, you guys.  BUBECK: Thank you, Peter. Thanks, Bill.  LEE: I just always feel such a sense of privilege to have a chance to interact and actually work with people like Bill and Sébastien.    With Bill, I’m always amazed at how practically minded he is. He’s really thinking about the nuts and bolts of what AI might be able to do for people, and his thoughts about underserved parts of the world, the idea that we might actually be able to empower people with access to expert medical knowledge, I think is both inspiring and amazing.   And then, Seb, Sébastien Bubeck, he’s just absolutely a brilliant mind. He has a really firm grip on the deep mathematics of artificial intelligence and brings that to bear in his research and development work. And where that mathematics takes him isn’t just into the nuts and bolts of algorithms but into philosophical questions about the nature of intelligence.   One of the things that Sébastien brought up was the state of evaluation of AI systems. And indeed, he was fairly critical in our conversation. But of course, the world of AI research and development is just moving so fast, and indeed, since we recorded our conversation, OpenAI, in fact, released a new evaluation metric that is directly relevant to medical applications, and that is something called HealthBench. And Microsoft Research also released a new evaluation approach or process called ADeLe.   HealthBench and ADeLe are examples of new approaches to evaluating AI models that are less about testing their knowledge and ability to pass multiple-choice exams and instead are evaluation approaches designed to assess how well AI models are able to complete tasks that actually arise every day in typical healthcare or biomedical research settings. These are examples of really important good work that speak to how well AI models work in the real world of healthcare and biomedical research and how well they can collaborate with human beings in those settings.  You know, I asked Bill and Seb to make some predictions about the future. You know, my own answer, I expect that we’re going to be able to use AI to change how we diagnose patients, change how we decide treatment options.   If you’re a doctor or a nurse and you encounter a patient, you’ll ask questions, do a physical exam, you know, call out for labs just like you do today, but then you’ll be able to engage with AI based on all of that data and just ask, you know, based on all the other people who have gone through the same experience, who have similar data, how were they diagnosed? How were they treated? What were their outcomes? And what does that mean for the patient I have right now? Some people call it the “patients like me” paradigm. And I think that’s going to become real because of AI within our lifetimes. That idea of really grounding the delivery in healthcare and medical practice through data and intelligence, I actually now don’t see any barriers to that future becoming real.  [THEME MUSIC]  I’d like to extend another big thank you to Bill and Sébastien for their time. And to our listeners, as always, it’s a pleasure to have you along for the ride. I hope you’ll join us for our remaining conversations, as well as a second coauthor roundtable with Carey and Zak.   Until next time.   [MUSIC FADES]
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  • Five Climate Issues to Watch When Trump Goes to Canada

    June 13, 20255 min readFive Climate Issues to Watch When Trump Goes to CanadaPresident Trump will attend the G7 summit on Sunday in a nation he threatened to annex. He will also be an outlier on climate issuesBy Sara Schonhardt & E&E News Saul Loeb/AFP via Getty ImagesCLIMATEWIRE | The world’s richest nations are gathering Sunday in the Canadian Rockies for a summit that could reveal whether President Donald Trump's policies are shaking global climate efforts.The Group of Seven meeting comes at a challenging time for international climate policy. Trump’s tariff seesaw has cast a shade over the global economy, and his domestic policies have threatened billions of dollars in funding for clean energy programs. Those pressures are colliding with record-breaking temperatures worldwide and explosive demand for energy, driven by power-hungry data centers linked to artificial intelligence technologies.On top of that, Trump has threatened to annex the host of the meeting — Canada — and members of his Cabinet have taken swipes at Europe’s use of renewable energy. Rather than being aligned with much of the world's assertion that fossil fuels should be tempered, Trump embraces the opposite position — drill for more oil and gas and keep burning coal, while repealing environmental regulations on the biggest sources of U.S. carbon pollution.On supporting science journalismIf you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.Those moves illustrate his rejection of climate science and underscore his outlying positions on global warming in the G7.Here are five things to know about the summit.Who will be there?The group comprises Canada, France, Germany, Italy, Japan, the United Kingdom and the United States — plus the European Union. Together they account for more than 40 percent of gross domestic product globally and around a quarter of all energy-related carbon dioxide pollution, according to the International Energy Agency. The U.S. is the only one among them that is not trying to hit a carbon reduction goal.Some emerging economies have also been invited, including Mexico, India, South Africa and Brazil, the host of this year’s COP30 climate talks in November.Ahead of the meeting, the office of Canada's prime minister, Mark Carney, said he and Brazilian President Luiz Inácio Lula da Silva agreed to strengthen cooperation on energy security and critical minerals. White House press secretary Karoline Leavitt said Trump would be having "quite a few" bilateral meetings but that his schedule was in flux.The G7 first came together 50 years ago following the Arab oil embargo. Since then, its seven members have all joined the United Nations Framework Convention on Climate Change and the Paris Agreement. The U.S. is the only nation in the group that has withdrawn from the Paris Agreement, which counts almost every country in the world as a signatory.What’s on the table?Among Canada’s top priorities as host are strengthening energy security and fortifying critical mineral supply chains. Carney would also like to see some agreement on joint wildfire action.Expanding supply chains for critical minerals — and competing more aggressively with China over those resources — could be areas of common ground among the leaders. Climate change is expected to remain divisive. Looming over the discussions will be tariffs — which Trump has applied across the board — because they will have an impact on the clean energy transition.“I think probably the majority of the conversation will be less about climate per se, or certainly not using climate action as the frame, but more about energy transition and infrastructure as a way of kind of bridging the known gaps between most of the G7 and where the United States is right now,” said Dan Baer, director of the Europe program at the Carnegie Endowment for International Peace.What are the possible outcomes?The leaders could issue a communique at the end of their meeting, but those statements are based on consensus, something that would be difficult to reach without other G7 countries capitulating to Trump. Bloomberg reported Wednesday that nations won’t try to reach a joint agreement, in part because bridging gaps on climate change could be too hard.Instead, Carney could issue a chair’s summary or joint statements based on certain issues.The question is how far Canada will go to accommodate the U.S., which could try to roll back past statements on advancing clean energy, said Andrew Light, former assistant secretary of Energy for international affairs, who led ministerial-level negotiations for the G7.“They might say, rather than watering everything down that we accomplished in the last four years, we just do a chair's statement, which summarizes the debate,” Light said. “That will show you that you didn't get consensus, but you also didn't get capitulation.”What to watch forIf there is a communique, Light says he’ll be looking for whether there is tougher language on China and any signal of support for science and the Paris Agreement. During his first term, Trump refused to support the Paris accord in the G7 and G20 declarations.The statement could avoid climate and energy issues entirely. But if it backtracks on those issues, that could be a sign that countries made a deal by trading climate-related language for something else, Light said.Baer of Carnegie said a statement framed around energy security and infrastructure could be seen as a “pragmatic adaptation” to the U.S. administration, rather than an indication that other leaders aren’t concerned about climate change.Climate activists have lower expectations.“Realistically, we can expect very little, if any, mention of climate change,” said Caroline Brouillette, executive director of Climate Action Network Canada.“The message we should be expecting from those leaders is that climate action remains a priority for the rest of the G7 … whether it's on the transition away from fossil fuels and supporting developing countries through climate finance,” she said. “Especially now that the U.S. is stepping back, we need countries, including Canada, to be stepping up.”Best- and worst-case scenariosThe challenge for Carney will be preventing any further rupture with Trump, analysts said.In 2018, Trump made a hasty exit from the G7 summit, also in Canada that year, due largely to trade disagreements. He retracted his support for the joint statement.“The best,realistic case outcome is that things don't get worse,” said Baer.The worst-case scenario? Some kind of “highly personalized spat” that could add to the sense of disorder, he added.“I think the G7 on the one hand has the potential to be more important than ever, as fewer and fewer platforms for international cooperation seem to be able to take action,” Baer said. “So it's both very important and also I don't have super-high expectations.”Reprinted from E&E News with permission from POLITICO, LLC. Copyright 2025. E&E News provides essential news for energy and environment professionals.
    #five #climate #issues #watch #when
    Five Climate Issues to Watch When Trump Goes to Canada
    June 13, 20255 min readFive Climate Issues to Watch When Trump Goes to CanadaPresident Trump will attend the G7 summit on Sunday in a nation he threatened to annex. He will also be an outlier on climate issuesBy Sara Schonhardt & E&E News Saul Loeb/AFP via Getty ImagesCLIMATEWIRE | The world’s richest nations are gathering Sunday in the Canadian Rockies for a summit that could reveal whether President Donald Trump's policies are shaking global climate efforts.The Group of Seven meeting comes at a challenging time for international climate policy. Trump’s tariff seesaw has cast a shade over the global economy, and his domestic policies have threatened billions of dollars in funding for clean energy programs. Those pressures are colliding with record-breaking temperatures worldwide and explosive demand for energy, driven by power-hungry data centers linked to artificial intelligence technologies.On top of that, Trump has threatened to annex the host of the meeting — Canada — and members of his Cabinet have taken swipes at Europe’s use of renewable energy. Rather than being aligned with much of the world's assertion that fossil fuels should be tempered, Trump embraces the opposite position — drill for more oil and gas and keep burning coal, while repealing environmental regulations on the biggest sources of U.S. carbon pollution.On supporting science journalismIf you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.Those moves illustrate his rejection of climate science and underscore his outlying positions on global warming in the G7.Here are five things to know about the summit.Who will be there?The group comprises Canada, France, Germany, Italy, Japan, the United Kingdom and the United States — plus the European Union. Together they account for more than 40 percent of gross domestic product globally and around a quarter of all energy-related carbon dioxide pollution, according to the International Energy Agency. The U.S. is the only one among them that is not trying to hit a carbon reduction goal.Some emerging economies have also been invited, including Mexico, India, South Africa and Brazil, the host of this year’s COP30 climate talks in November.Ahead of the meeting, the office of Canada's prime minister, Mark Carney, said he and Brazilian President Luiz Inácio Lula da Silva agreed to strengthen cooperation on energy security and critical minerals. White House press secretary Karoline Leavitt said Trump would be having "quite a few" bilateral meetings but that his schedule was in flux.The G7 first came together 50 years ago following the Arab oil embargo. Since then, its seven members have all joined the United Nations Framework Convention on Climate Change and the Paris Agreement. The U.S. is the only nation in the group that has withdrawn from the Paris Agreement, which counts almost every country in the world as a signatory.What’s on the table?Among Canada’s top priorities as host are strengthening energy security and fortifying critical mineral supply chains. Carney would also like to see some agreement on joint wildfire action.Expanding supply chains for critical minerals — and competing more aggressively with China over those resources — could be areas of common ground among the leaders. Climate change is expected to remain divisive. Looming over the discussions will be tariffs — which Trump has applied across the board — because they will have an impact on the clean energy transition.“I think probably the majority of the conversation will be less about climate per se, or certainly not using climate action as the frame, but more about energy transition and infrastructure as a way of kind of bridging the known gaps between most of the G7 and where the United States is right now,” said Dan Baer, director of the Europe program at the Carnegie Endowment for International Peace.What are the possible outcomes?The leaders could issue a communique at the end of their meeting, but those statements are based on consensus, something that would be difficult to reach without other G7 countries capitulating to Trump. Bloomberg reported Wednesday that nations won’t try to reach a joint agreement, in part because bridging gaps on climate change could be too hard.Instead, Carney could issue a chair’s summary or joint statements based on certain issues.The question is how far Canada will go to accommodate the U.S., which could try to roll back past statements on advancing clean energy, said Andrew Light, former assistant secretary of Energy for international affairs, who led ministerial-level negotiations for the G7.“They might say, rather than watering everything down that we accomplished in the last four years, we just do a chair's statement, which summarizes the debate,” Light said. “That will show you that you didn't get consensus, but you also didn't get capitulation.”What to watch forIf there is a communique, Light says he’ll be looking for whether there is tougher language on China and any signal of support for science and the Paris Agreement. During his first term, Trump refused to support the Paris accord in the G7 and G20 declarations.The statement could avoid climate and energy issues entirely. But if it backtracks on those issues, that could be a sign that countries made a deal by trading climate-related language for something else, Light said.Baer of Carnegie said a statement framed around energy security and infrastructure could be seen as a “pragmatic adaptation” to the U.S. administration, rather than an indication that other leaders aren’t concerned about climate change.Climate activists have lower expectations.“Realistically, we can expect very little, if any, mention of climate change,” said Caroline Brouillette, executive director of Climate Action Network Canada.“The message we should be expecting from those leaders is that climate action remains a priority for the rest of the G7 … whether it's on the transition away from fossil fuels and supporting developing countries through climate finance,” she said. “Especially now that the U.S. is stepping back, we need countries, including Canada, to be stepping up.”Best- and worst-case scenariosThe challenge for Carney will be preventing any further rupture with Trump, analysts said.In 2018, Trump made a hasty exit from the G7 summit, also in Canada that year, due largely to trade disagreements. He retracted his support for the joint statement.“The best,realistic case outcome is that things don't get worse,” said Baer.The worst-case scenario? Some kind of “highly personalized spat” that could add to the sense of disorder, he added.“I think the G7 on the one hand has the potential to be more important than ever, as fewer and fewer platforms for international cooperation seem to be able to take action,” Baer said. “So it's both very important and also I don't have super-high expectations.”Reprinted from E&E News with permission from POLITICO, LLC. Copyright 2025. E&E News provides essential news for energy and environment professionals. #five #climate #issues #watch #when
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    Five Climate Issues to Watch When Trump Goes to Canada
    June 13, 20255 min readFive Climate Issues to Watch When Trump Goes to CanadaPresident Trump will attend the G7 summit on Sunday in a nation he threatened to annex. He will also be an outlier on climate issuesBy Sara Schonhardt & E&E News Saul Loeb/AFP via Getty ImagesCLIMATEWIRE | The world’s richest nations are gathering Sunday in the Canadian Rockies for a summit that could reveal whether President Donald Trump's policies are shaking global climate efforts.The Group of Seven meeting comes at a challenging time for international climate policy. Trump’s tariff seesaw has cast a shade over the global economy, and his domestic policies have threatened billions of dollars in funding for clean energy programs. Those pressures are colliding with record-breaking temperatures worldwide and explosive demand for energy, driven by power-hungry data centers linked to artificial intelligence technologies.On top of that, Trump has threatened to annex the host of the meeting — Canada — and members of his Cabinet have taken swipes at Europe’s use of renewable energy. Rather than being aligned with much of the world's assertion that fossil fuels should be tempered, Trump embraces the opposite position — drill for more oil and gas and keep burning coal, while repealing environmental regulations on the biggest sources of U.S. carbon pollution.On supporting science journalismIf you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.Those moves illustrate his rejection of climate science and underscore his outlying positions on global warming in the G7.Here are five things to know about the summit.Who will be there?The group comprises Canada, France, Germany, Italy, Japan, the United Kingdom and the United States — plus the European Union. Together they account for more than 40 percent of gross domestic product globally and around a quarter of all energy-related carbon dioxide pollution, according to the International Energy Agency. The U.S. is the only one among them that is not trying to hit a carbon reduction goal.Some emerging economies have also been invited, including Mexico, India, South Africa and Brazil, the host of this year’s COP30 climate talks in November.Ahead of the meeting, the office of Canada's prime minister, Mark Carney, said he and Brazilian President Luiz Inácio Lula da Silva agreed to strengthen cooperation on energy security and critical minerals. White House press secretary Karoline Leavitt said Trump would be having "quite a few" bilateral meetings but that his schedule was in flux.The G7 first came together 50 years ago following the Arab oil embargo. Since then, its seven members have all joined the United Nations Framework Convention on Climate Change and the Paris Agreement. The U.S. is the only nation in the group that has withdrawn from the Paris Agreement, which counts almost every country in the world as a signatory.What’s on the table?Among Canada’s top priorities as host are strengthening energy security and fortifying critical mineral supply chains. Carney would also like to see some agreement on joint wildfire action.Expanding supply chains for critical minerals — and competing more aggressively with China over those resources — could be areas of common ground among the leaders. Climate change is expected to remain divisive. Looming over the discussions will be tariffs — which Trump has applied across the board — because they will have an impact on the clean energy transition.“I think probably the majority of the conversation will be less about climate per se, or certainly not using climate action as the frame, but more about energy transition and infrastructure as a way of kind of bridging the known gaps between most of the G7 and where the United States is right now,” said Dan Baer, director of the Europe program at the Carnegie Endowment for International Peace.What are the possible outcomes?The leaders could issue a communique at the end of their meeting, but those statements are based on consensus, something that would be difficult to reach without other G7 countries capitulating to Trump. Bloomberg reported Wednesday that nations won’t try to reach a joint agreement, in part because bridging gaps on climate change could be too hard.Instead, Carney could issue a chair’s summary or joint statements based on certain issues.The question is how far Canada will go to accommodate the U.S., which could try to roll back past statements on advancing clean energy, said Andrew Light, former assistant secretary of Energy for international affairs, who led ministerial-level negotiations for the G7.“They might say, rather than watering everything down that we accomplished in the last four years, we just do a chair's statement, which summarizes the debate,” Light said. “That will show you that you didn't get consensus, but you also didn't get capitulation.”What to watch forIf there is a communique, Light says he’ll be looking for whether there is tougher language on China and any signal of support for science and the Paris Agreement. During his first term, Trump refused to support the Paris accord in the G7 and G20 declarations.The statement could avoid climate and energy issues entirely. But if it backtracks on those issues, that could be a sign that countries made a deal by trading climate-related language for something else, Light said.Baer of Carnegie said a statement framed around energy security and infrastructure could be seen as a “pragmatic adaptation” to the U.S. administration, rather than an indication that other leaders aren’t concerned about climate change.Climate activists have lower expectations.“Realistically, we can expect very little, if any, mention of climate change,” said Caroline Brouillette, executive director of Climate Action Network Canada.“The message we should be expecting from those leaders is that climate action remains a priority for the rest of the G7 … whether it's on the transition away from fossil fuels and supporting developing countries through climate finance,” she said. “Especially now that the U.S. is stepping back, we need countries, including Canada, to be stepping up.”Best- and worst-case scenariosThe challenge for Carney will be preventing any further rupture with Trump, analysts said.In 2018, Trump made a hasty exit from the G7 summit, also in Canada that year, due largely to trade disagreements. He retracted his support for the joint statement.“The best, [most] realistic case outcome is that things don't get worse,” said Baer.The worst-case scenario? Some kind of “highly personalized spat” that could add to the sense of disorder, he added.“I think the G7 on the one hand has the potential to be more important than ever, as fewer and fewer platforms for international cooperation seem to be able to take action,” Baer said. “So it's both very important and also I don't have super-high expectations.”Reprinted from E&E News with permission from POLITICO, LLC. Copyright 2025. E&E News provides essential news for energy and environment professionals.
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  • Apple TV+ Drops ‘Foundation’ Season 3 Trailer

    It's less than a month away! Apple TV+ has unveiled the trailer for Foundation Season 3. Based on Isaac Asimov’s epic, seminal sci-fi stories and starring Jared Harris, Lee Pace, and Lou Llobell, the upcoming season will debut globally with one episode on July 11 on Apple TV+, followed by episodes every Friday through September 12.
    Season 3, which is set 152 years after the events of Season 2, continues the epic chronicle of a band of exiles on their journey to save humanity and rebuild civilization amid the fall of the Galactic Empire.  We get to see more of how prescient, and important, Hari Seldon’s theories of psychohistory become.
    Newcomers to the franchise include Cherry Jones, Brandon P. Bell, Synnøve Karlsen, Cody Fern, Tómas Lemarquis, Alexander Siddig, Troy Kotsur, and Pilou Asbæk. Returning cast includes Laura Birn, Cassian Bilton, Terrence Mann, and Rowena King.
    Under overall VFX supervisor Chris MacLean, VFX studios include Crafty Apes, Framestore, Outpost VFX, Rodeo FX, SSVFX, and Trend VFX.
    Foundation is produced for Apple by Skydance Television. David S. Goyer executive produces alongside Bill Bost, David Ellison, Dana Goldberg, Matt Thunell, Robyn Asimov, David Kob, Christopher J. Byrne, Leigh Dana Jackson, Jane Espenson and Roxann Dawson.
    Foundation Seasons 1 and 2 are streaming globally on Apple TV+.
    Check out the trailer now:

    Source: Apple TV+

    Journalist, antique shop owner, aspiring gemologist—L'Wren brings a diverse perspective to animation, where every frame reflects her varied passions.
    #apple #drops #foundation #season #trailer
    Apple TV+ Drops ‘Foundation’ Season 3 Trailer
    It's less than a month away! Apple TV+ has unveiled the trailer for Foundation Season 3. Based on Isaac Asimov’s epic, seminal sci-fi stories and starring Jared Harris, Lee Pace, and Lou Llobell, the upcoming season will debut globally with one episode on July 11 on Apple TV+, followed by episodes every Friday through September 12. Season 3, which is set 152 years after the events of Season 2, continues the epic chronicle of a band of exiles on their journey to save humanity and rebuild civilization amid the fall of the Galactic Empire.  We get to see more of how prescient, and important, Hari Seldon’s theories of psychohistory become. Newcomers to the franchise include Cherry Jones, Brandon P. Bell, Synnøve Karlsen, Cody Fern, Tómas Lemarquis, Alexander Siddig, Troy Kotsur, and Pilou Asbæk. Returning cast includes Laura Birn, Cassian Bilton, Terrence Mann, and Rowena King. Under overall VFX supervisor Chris MacLean, VFX studios include Crafty Apes, Framestore, Outpost VFX, Rodeo FX, SSVFX, and Trend VFX. Foundation is produced for Apple by Skydance Television. David S. Goyer executive produces alongside Bill Bost, David Ellison, Dana Goldberg, Matt Thunell, Robyn Asimov, David Kob, Christopher J. Byrne, Leigh Dana Jackson, Jane Espenson and Roxann Dawson. Foundation Seasons 1 and 2 are streaming globally on Apple TV+. Check out the trailer now: Source: Apple TV+ Journalist, antique shop owner, aspiring gemologist—L'Wren brings a diverse perspective to animation, where every frame reflects her varied passions. #apple #drops #foundation #season #trailer
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    Apple TV+ Drops ‘Foundation’ Season 3 Trailer
    It's less than a month away! Apple TV+ has unveiled the trailer for Foundation Season 3. Based on Isaac Asimov’s epic, seminal sci-fi stories and starring Jared Harris, Lee Pace, and Lou Llobell, the upcoming season will debut globally with one episode on July 11 on Apple TV+, followed by episodes every Friday through September 12. Season 3, which is set 152 years after the events of Season 2, continues the epic chronicle of a band of exiles on their journey to save humanity and rebuild civilization amid the fall of the Galactic Empire.  We get to see more of how prescient, and important, Hari Seldon’s theories of psychohistory become. Newcomers to the franchise include Cherry Jones, Brandon P. Bell, Synnøve Karlsen, Cody Fern, Tómas Lemarquis, Alexander Siddig, Troy Kotsur, and Pilou Asbæk. Returning cast includes Laura Birn, Cassian Bilton, Terrence Mann, and Rowena King. Under overall VFX supervisor Chris MacLean, VFX studios include Crafty Apes, Framestore, Outpost VFX, Rodeo FX, SSVFX, and Trend VFX. Foundation is produced for Apple by Skydance Television. David S. Goyer executive produces alongside Bill Bost, David Ellison, Dana Goldberg, Matt Thunell, Robyn Asimov, David Kob, Christopher J. Byrne, Leigh Dana Jackson, Jane Espenson and Roxann Dawson. Foundation Seasons 1 and 2 are streaming globally on Apple TV+. Check out the trailer now: Source: Apple TV+ Journalist, antique shop owner, aspiring gemologist—L'Wren brings a diverse perspective to animation, where every frame reflects her varied passions.
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  • Ansys: UX Designer II (Remote - US)

    Requisition #: 16391 Our Mission: Powering Innovation That Drives Human Advancement When visionary companies need to know how their world-changing ideas will perform, they close the gap between design and reality with Ansys simulation. For more than 50 years, Ansys software has enabled innovators across industries to push boundaries by using the predictive power of simulation. From sustainable transportation to advanced semiconductors, from satellite systems to life-saving medical devices, the next great leaps in human advancement will be powered by Ansys. Innovate With Ansys, Power Your Career. Summary / Role Purpose The User Experience Designer II creates easy and delightful experiences for users interacting with ANSYS products and services. The UX designer assesses the functional and content requirements of a product, develops storyboards, creates wireframes and task flows based on user needs, and produces visually detailed mockups. A passion for visual design and familiarity with UI trends and technologies are essential in this role, enabling the UX designer to bring fresh and innovative ideas to a project. This is an intermediate role, heavily focused on content production and communication. It is intended to expose the UX professional to the nuts-and-bolts aspects of their UX career; while building on presentation, communication, and usability aspects of the design role. The User Experience Designer II will contribute to the development of a new web-based, collaborative solution for the ModelCenter and optiSLang product lines. This work will be based on an innovative modeling framework, modern web technologies, micro-services and integrations with Ansys' core products. The User Experience Designer II will contribute to the specification and design of user interactions and workflows for new features. The solution will be used by Ansys customers to design next generation systems in the most innovative industries. Location: Can be 100% Remote within US Key Duties and Responsibilities Designs, develops, and evaluates cutting-edge user interfaces Reviews UX artifacts created by other UX team members Utilizes prototyping tools and UX toolkits Creates and delivers usability studies Communicates design rationale across product creation disciplines and personnel Records usability/UX problems with clear explanations and recommendations for improvement Works closely with product managers, development teams, and other designers Minimum Education/Certification Requirements and Experience BS or BA in Human-Computer Interaction, Design Engineering, or Industrial Design with 2 years' experience or MS Working experience with technical software development proven by academic, research, or industry projects. Professional working proficiency in English Preferred Qualifications and Skills Experience with: UX design and collaboration tools: Figma, Balsamiq or similar tools Tools & technologies for UI implementation: HTML, CSS, JavaScript, Angular, React Screen-capture/editing/video-editing tools Adobe Creative Suite Ability to: Smoothly iterate on designs, taking direction, adjusting, and re-focusing towards a converged design Organize deliverables for future reflection and current investigations Communicate succinctly and professionally via email, chat, remote meetings, usability evaluations, etc. Prototype rapidly using any tools available Knowledge of Model Based System Engineeringor optimization is a plus Culture and Values Culture and values are incredibly important to ANSYS. They inform us of who we are, of how we act. Values aren't posters hanging on a wall or about trite or glib slogans. They aren't about rules and regulations. They can't just be handed down the organization. They are shared beliefs - guideposts that we all follow when we're facing a challenge or a decision. Our values tell us how we live our lives; how we approach our jobs. Our values are crucial for fostering a culture of winning for our company: • Customer focus • Results and Accountability • Innovation • Transparency and Integrity • Mastery • Inclusiveness • Sense of urgency • Collaboration and Teamwork At Ansys, we know that changing the world takes vision, skill, and each other. We fuel new ideas, build relationships, and help each other realize our greatest potential. We are ONE Ansys. We operate on three key components: our commitments to stakeholders, our values that guide how we work together, and our actions to deliver results. As ONE Ansys, we are powering innovation that drives human advancement Our Commitments:Amaze with innovative products and solutionsMake our customers incredibly successfulAct with integrityEnsure employees thrive and shareholders prosper Our Values:Adaptability: Be open, welcome what's nextCourage: Be courageous, move forward passionatelyGenerosity: Be generous, share, listen, serveAuthenticity: Be you, make us stronger Our Actions:We commit to audacious goalsWe work seamlessly as a teamWe demonstrate masteryWe deliver outstanding resultsVALUES IN ACTION Ansys is committed to powering the people who power human advancement. We believe in creating and nurturing a workplace that supports and welcomes people of all backgrounds; encouraging them to bring their talents and experience to a workplace where they are valued and can thrive. Our culture is grounded in our four core values of adaptability, courage, generosity, and authenticity. Through our behaviors and actions, these values foster higher team performance and greater innovation for our customers. We're proud to offer programs, available to all employees, to further impact innovation and business outcomes, such as employee networks and learning communities that inform solutions for our globally minded customer base. WELCOME WHAT'S NEXT IN YOUR CAREER AT ANSYS At Ansys, you will find yourself among the sharpest minds and most visionary leaders across the globe. Collectively, we strive to change the world with innovative technology and transformational solutions. With a prestigious reputation in working with well-known, world-class companies, standards at Ansys are high - met by those willing to rise to the occasion and meet those challenges head on. Our team is passionate about pushing the limits of world-class simulation technology, empowering our customers to turn their design concepts into successful, innovative products faster and at a lower cost. Ready to feel inspired? Check out some of our recent customer stories, here and here . At Ansys, it's about the learning, the discovery, and the collaboration. It's about the "what's next" as much as the "mission accomplished." And it's about the melding of disciplined intellect with strategic direction and results that have, can, and do impact real people in real ways. All this is forged within a working environment built on respect, autonomy, and ethics.CREATING A PLACE WE'RE PROUD TO BEAnsys is an S&P 500 company and a member of the NASDAQ-100. We are proud to have been recognized for the following more recent awards, although our list goes on: Newsweek's Most Loved Workplace globally and in the U.S., Gold Stevie Award Winner, America's Most Responsible Companies, Fast Company World Changing Ideas, Great Place to Work Certified.For more information, please visit us at Ansys is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other protected characteristics.Ansys does not accept unsolicited referrals for vacancies, and any unsolicited referral will become the property of Ansys. Upon hire, no fee will be owed to the agency, person, or entity.Apply NowLet's start your dream job Apply now Meet JobCopilot: Your Personal AI Job HunterAutomatically Apply to Remote Full-Stack Programming JobsJust set your preferences and Job Copilot will do the rest-finding, filtering, and applying while you focus on what matters. Activate JobCopilot
    #ansys #designer #remote
    Ansys: UX Designer II (Remote - US)
    Requisition #: 16391 Our Mission: Powering Innovation That Drives Human Advancement When visionary companies need to know how their world-changing ideas will perform, they close the gap between design and reality with Ansys simulation. For more than 50 years, Ansys software has enabled innovators across industries to push boundaries by using the predictive power of simulation. From sustainable transportation to advanced semiconductors, from satellite systems to life-saving medical devices, the next great leaps in human advancement will be powered by Ansys. Innovate With Ansys, Power Your Career. Summary / Role Purpose The User Experience Designer II creates easy and delightful experiences for users interacting with ANSYS products and services. The UX designer assesses the functional and content requirements of a product, develops storyboards, creates wireframes and task flows based on user needs, and produces visually detailed mockups. A passion for visual design and familiarity with UI trends and technologies are essential in this role, enabling the UX designer to bring fresh and innovative ideas to a project. This is an intermediate role, heavily focused on content production and communication. It is intended to expose the UX professional to the nuts-and-bolts aspects of their UX career; while building on presentation, communication, and usability aspects of the design role. The User Experience Designer II will contribute to the development of a new web-based, collaborative solution for the ModelCenter and optiSLang product lines. This work will be based on an innovative modeling framework, modern web technologies, micro-services and integrations with Ansys' core products. The User Experience Designer II will contribute to the specification and design of user interactions and workflows for new features. The solution will be used by Ansys customers to design next generation systems in the most innovative industries. Location: Can be 100% Remote within US Key Duties and Responsibilities Designs, develops, and evaluates cutting-edge user interfaces Reviews UX artifacts created by other UX team members Utilizes prototyping tools and UX toolkits Creates and delivers usability studies Communicates design rationale across product creation disciplines and personnel Records usability/UX problems with clear explanations and recommendations for improvement Works closely with product managers, development teams, and other designers Minimum Education/Certification Requirements and Experience BS or BA in Human-Computer Interaction, Design Engineering, or Industrial Design with 2 years' experience or MS Working experience with technical software development proven by academic, research, or industry projects. Professional working proficiency in English Preferred Qualifications and Skills Experience with: UX design and collaboration tools: Figma, Balsamiq or similar tools Tools & technologies for UI implementation: HTML, CSS, JavaScript, Angular, React Screen-capture/editing/video-editing tools Adobe Creative Suite Ability to: Smoothly iterate on designs, taking direction, adjusting, and re-focusing towards a converged design Organize deliverables for future reflection and current investigations Communicate succinctly and professionally via email, chat, remote meetings, usability evaluations, etc. Prototype rapidly using any tools available Knowledge of Model Based System Engineeringor optimization is a plus Culture and Values Culture and values are incredibly important to ANSYS. They inform us of who we are, of how we act. Values aren't posters hanging on a wall or about trite or glib slogans. They aren't about rules and regulations. They can't just be handed down the organization. They are shared beliefs - guideposts that we all follow when we're facing a challenge or a decision. Our values tell us how we live our lives; how we approach our jobs. Our values are crucial for fostering a culture of winning for our company: • Customer focus • Results and Accountability • Innovation • Transparency and Integrity • Mastery • Inclusiveness • Sense of urgency • Collaboration and Teamwork At Ansys, we know that changing the world takes vision, skill, and each other. We fuel new ideas, build relationships, and help each other realize our greatest potential. We are ONE Ansys. We operate on three key components: our commitments to stakeholders, our values that guide how we work together, and our actions to deliver results. As ONE Ansys, we are powering innovation that drives human advancement Our Commitments:Amaze with innovative products and solutionsMake our customers incredibly successfulAct with integrityEnsure employees thrive and shareholders prosper Our Values:Adaptability: Be open, welcome what's nextCourage: Be courageous, move forward passionatelyGenerosity: Be generous, share, listen, serveAuthenticity: Be you, make us stronger Our Actions:We commit to audacious goalsWe work seamlessly as a teamWe demonstrate masteryWe deliver outstanding resultsVALUES IN ACTION Ansys is committed to powering the people who power human advancement. We believe in creating and nurturing a workplace that supports and welcomes people of all backgrounds; encouraging them to bring their talents and experience to a workplace where they are valued and can thrive. Our culture is grounded in our four core values of adaptability, courage, generosity, and authenticity. Through our behaviors and actions, these values foster higher team performance and greater innovation for our customers. We're proud to offer programs, available to all employees, to further impact innovation and business outcomes, such as employee networks and learning communities that inform solutions for our globally minded customer base. WELCOME WHAT'S NEXT IN YOUR CAREER AT ANSYS At Ansys, you will find yourself among the sharpest minds and most visionary leaders across the globe. Collectively, we strive to change the world with innovative technology and transformational solutions. With a prestigious reputation in working with well-known, world-class companies, standards at Ansys are high - met by those willing to rise to the occasion and meet those challenges head on. Our team is passionate about pushing the limits of world-class simulation technology, empowering our customers to turn their design concepts into successful, innovative products faster and at a lower cost. Ready to feel inspired? Check out some of our recent customer stories, here and here . At Ansys, it's about the learning, the discovery, and the collaboration. It's about the "what's next" as much as the "mission accomplished." And it's about the melding of disciplined intellect with strategic direction and results that have, can, and do impact real people in real ways. All this is forged within a working environment built on respect, autonomy, and ethics.CREATING A PLACE WE'RE PROUD TO BEAnsys is an S&P 500 company and a member of the NASDAQ-100. We are proud to have been recognized for the following more recent awards, although our list goes on: Newsweek's Most Loved Workplace globally and in the U.S., Gold Stevie Award Winner, America's Most Responsible Companies, Fast Company World Changing Ideas, Great Place to Work Certified.For more information, please visit us at Ansys is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other protected characteristics.Ansys does not accept unsolicited referrals for vacancies, and any unsolicited referral will become the property of Ansys. Upon hire, no fee will be owed to the agency, person, or entity.Apply NowLet's start your dream job Apply now Meet JobCopilot: Your Personal AI Job HunterAutomatically Apply to Remote Full-Stack Programming JobsJust set your preferences and Job Copilot will do the rest-finding, filtering, and applying while you focus on what matters. Activate JobCopilot #ansys #designer #remote
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    Ansys: UX Designer II (Remote - US)
    Requisition #: 16391 Our Mission: Powering Innovation That Drives Human Advancement When visionary companies need to know how their world-changing ideas will perform, they close the gap between design and reality with Ansys simulation. For more than 50 years, Ansys software has enabled innovators across industries to push boundaries by using the predictive power of simulation. From sustainable transportation to advanced semiconductors, from satellite systems to life-saving medical devices, the next great leaps in human advancement will be powered by Ansys. Innovate With Ansys, Power Your Career. Summary / Role Purpose The User Experience Designer II creates easy and delightful experiences for users interacting with ANSYS products and services. The UX designer assesses the functional and content requirements of a product, develops storyboards, creates wireframes and task flows based on user needs, and produces visually detailed mockups. A passion for visual design and familiarity with UI trends and technologies are essential in this role, enabling the UX designer to bring fresh and innovative ideas to a project. This is an intermediate role, heavily focused on content production and communication. It is intended to expose the UX professional to the nuts-and-bolts aspects of their UX career; while building on presentation, communication, and usability aspects of the design role. The User Experience Designer II will contribute to the development of a new web-based, collaborative solution for the ModelCenter and optiSLang product lines. This work will be based on an innovative modeling framework, modern web technologies, micro-services and integrations with Ansys' core products. The User Experience Designer II will contribute to the specification and design of user interactions and workflows for new features. The solution will be used by Ansys customers to design next generation systems in the most innovative industries (Aerospace and Defense, Automotive, semi-conductors, and others). Location: Can be 100% Remote within US Key Duties and Responsibilities Designs, develops, and evaluates cutting-edge user interfaces Reviews UX artifacts created by other UX team members Utilizes prototyping tools and UX toolkits Creates and delivers usability studies Communicates design rationale across product creation disciplines and personnel Records usability/UX problems with clear explanations and recommendations for improvement Works closely with product managers, development teams, and other designers Minimum Education/Certification Requirements and Experience BS or BA in Human-Computer Interaction, Design Engineering, or Industrial Design with 2 years' experience or MS Working experience with technical software development proven by academic, research, or industry projects. Professional working proficiency in English Preferred Qualifications and Skills Experience with: UX design and collaboration tools: Figma, Balsamiq or similar tools Tools & technologies for UI implementation: HTML, CSS, JavaScript, Angular, React Screen-capture/editing/video-editing tools Adobe Creative Suite Ability to: Smoothly iterate on designs, taking direction, adjusting, and re-focusing towards a converged design Organize deliverables for future reflection and current investigations Communicate succinctly and professionally via email, chat, remote meetings, usability evaluations, etc. Prototype rapidly using any tools available Knowledge of Model Based System Engineering (MBSE) or optimization is a plus Culture and Values Culture and values are incredibly important to ANSYS. They inform us of who we are, of how we act. Values aren't posters hanging on a wall or about trite or glib slogans. They aren't about rules and regulations. They can't just be handed down the organization. They are shared beliefs - guideposts that we all follow when we're facing a challenge or a decision. Our values tell us how we live our lives; how we approach our jobs. Our values are crucial for fostering a culture of winning for our company: • Customer focus • Results and Accountability • Innovation • Transparency and Integrity • Mastery • Inclusiveness • Sense of urgency • Collaboration and Teamwork At Ansys, we know that changing the world takes vision, skill, and each other. We fuel new ideas, build relationships, and help each other realize our greatest potential. We are ONE Ansys. We operate on three key components: our commitments to stakeholders, our values that guide how we work together, and our actions to deliver results. As ONE Ansys, we are powering innovation that drives human advancement Our Commitments:Amaze with innovative products and solutionsMake our customers incredibly successfulAct with integrityEnsure employees thrive and shareholders prosper Our Values:Adaptability: Be open, welcome what's nextCourage: Be courageous, move forward passionatelyGenerosity: Be generous, share, listen, serveAuthenticity: Be you, make us stronger Our Actions:We commit to audacious goalsWe work seamlessly as a teamWe demonstrate masteryWe deliver outstanding resultsVALUES IN ACTION Ansys is committed to powering the people who power human advancement. We believe in creating and nurturing a workplace that supports and welcomes people of all backgrounds; encouraging them to bring their talents and experience to a workplace where they are valued and can thrive. Our culture is grounded in our four core values of adaptability, courage, generosity, and authenticity. Through our behaviors and actions, these values foster higher team performance and greater innovation for our customers. We're proud to offer programs, available to all employees, to further impact innovation and business outcomes, such as employee networks and learning communities that inform solutions for our globally minded customer base. WELCOME WHAT'S NEXT IN YOUR CAREER AT ANSYS At Ansys, you will find yourself among the sharpest minds and most visionary leaders across the globe. Collectively, we strive to change the world with innovative technology and transformational solutions. With a prestigious reputation in working with well-known, world-class companies, standards at Ansys are high - met by those willing to rise to the occasion and meet those challenges head on. Our team is passionate about pushing the limits of world-class simulation technology, empowering our customers to turn their design concepts into successful, innovative products faster and at a lower cost. Ready to feel inspired? Check out some of our recent customer stories, here and here . At Ansys, it's about the learning, the discovery, and the collaboration. It's about the "what's next" as much as the "mission accomplished." And it's about the melding of disciplined intellect with strategic direction and results that have, can, and do impact real people in real ways. All this is forged within a working environment built on respect, autonomy, and ethics.CREATING A PLACE WE'RE PROUD TO BEAnsys is an S&P 500 company and a member of the NASDAQ-100. We are proud to have been recognized for the following more recent awards, although our list goes on: Newsweek's Most Loved Workplace globally and in the U.S., Gold Stevie Award Winner, America's Most Responsible Companies, Fast Company World Changing Ideas, Great Place to Work Certified (China, Greece, France, India, Japan, Korea, Spain, Sweden, Taiwan, and U.K.).For more information, please visit us at Ansys is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other protected characteristics.Ansys does not accept unsolicited referrals for vacancies, and any unsolicited referral will become the property of Ansys. Upon hire, no fee will be owed to the agency, person, or entity.Apply NowLet's start your dream job Apply now Meet JobCopilot: Your Personal AI Job HunterAutomatically Apply to Remote Full-Stack Programming JobsJust set your preferences and Job Copilot will do the rest-finding, filtering, and applying while you focus on what matters. Activate JobCopilot
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  • Rethinking AI: DeepSeek’s playbook shakes up the high-spend, high-compute paradigm

    Join the event trusted by enterprise leaders for nearly two decades. VB Transform brings together the people building real enterprise AI strategy. Learn more

    When DeepSeek released its R1 model this January, it wasn’t just another AI announcement. It was a watershed moment that sent shockwaves through the tech industry, forcing industry leaders to reconsider their fundamental approaches to AI development.
    What makes DeepSeek’s accomplishment remarkable isn’t that the company developed novel capabilities; rather, it was how it achieved comparable results to those delivered by tech heavyweights at a fraction of the cost. In reality, DeepSeek didn’t do anything that hadn’t been done before; its innovation stemmed from pursuing different priorities. As a result, we are now experiencing rapid-fire development along two parallel tracks: efficiency and compute. 
    As DeepSeek prepares to release its R2 model, and as it concurrently faces the potential of even greater chip restrictions from the U.S., it’s important to look at how it captured so much attention.
    Engineering around constraints
    DeepSeek’s arrival, as sudden and dramatic as it was, captivated us all because it showcased the capacity for innovation to thrive even under significant constraints. Faced with U.S. export controls limiting access to cutting-edge AI chips, DeepSeek was forced to find alternative pathways to AI advancement.
    While U.S. companies pursued performance gains through more powerful hardware, bigger models and better data, DeepSeek focused on optimizing what was available. It implemented known ideas with remarkable execution — and there is novelty in executing what’s known and doing it well.
    This efficiency-first mindset yielded incredibly impressive results. DeepSeek’s R1 model reportedly matches OpenAI’s capabilities at just 5 to 10% of the operating cost. According to reports, the final training run for DeepSeek’s V3 predecessor cost a mere million — which was described by former Tesla AI scientist Andrej Karpathy as “a joke of a budget” compared to the tens or hundreds of millions spent by U.S. competitors. More strikingly, while OpenAI reportedly spent million training its recent “Orion” model, DeepSeek achieved superior benchmark results for just million — less than 1.2% of OpenAI’s investment.
    If you get starry eyed believing these incredible results were achieved even as DeepSeek was at a severe disadvantage based on its inability to access advanced AI chips, I hate to tell you, but that narrative isn’t entirely accurate. Initial U.S. export controls focused primarily on compute capabilities, not on memory and networking — two crucial components for AI development.
    That means that the chips DeepSeek had access to were not poor quality chips; their networking and memory capabilities allowed DeepSeek to parallelize operations across many units, a key strategy for running their large model efficiently.
    This, combined with China’s national push toward controlling the entire vertical stack of AI infrastructure, resulted in accelerated innovation that many Western observers didn’t anticipate. DeepSeek’s advancements were an inevitable part of AI development, but they brought known advancements forward a few years earlier than would have been possible otherwise, and that’s pretty amazing.
    Pragmatism over process
    Beyond hardware optimization, DeepSeek’s approach to training data represents another departure from conventional Western practices. Rather than relying solely on web-scraped content, DeepSeek reportedly leveraged significant amounts of synthetic data and outputs from other proprietary models. This is a classic example of model distillation, or the ability to learn from really powerful models. Such an approach, however, raises questions about data privacy and governance that might concern Western enterprise customers. Still, it underscores DeepSeek’s overall pragmatic focus on results over process.
    The effective use of synthetic data is a key differentiator. Synthetic data can be very effective when it comes to training large models, but you have to be careful; some model architectures handle synthetic data better than others. For instance, transformer-based models with mixture of expertsarchitectures like DeepSeek’s tend to be more robust when incorporating synthetic data, while more traditional dense architectures like those used in early Llama models can experience performance degradation or even “model collapse” when trained on too much synthetic content.
    This architectural sensitivity matters because synthetic data introduces different patterns and distributions compared to real-world data. When a model architecture doesn’t handle synthetic data well, it may learn shortcuts or biases present in the synthetic data generation process rather than generalizable knowledge. This can lead to reduced performance on real-world tasks, increased hallucinations or brittleness when facing novel situations. 
    Still, DeepSeek’s engineering teams reportedly designed their model architecture specifically with synthetic data integration in mind from the earliest planning stages. This allowed the company to leverage the cost benefits of synthetic data without sacrificing performance.
    Market reverberations
    Why does all of this matter? Stock market aside, DeepSeek’s emergence has triggered substantive strategic shifts among industry leaders.
    Case in point: OpenAI. Sam Altman recently announced plans to release the company’s first “open-weight” language model since 2019. This is a pretty notable pivot for a company that built its business on proprietary systems. It seems DeepSeek’s rise, on top of Llama’s success, has hit OpenAI’s leader hard. Just a month after DeepSeek arrived on the scene, Altman admitted that OpenAI had been “on the wrong side of history” regarding open-source AI. 
    With OpenAI reportedly spending to 8 billion annually on operations, the economic pressure from efficient alternatives like DeepSeek has become impossible to ignore. As AI scholar Kai-Fu Lee bluntly put it: “You’re spending billion or billion a year, making a massive loss, and here you have a competitor coming in with an open-source model that’s for free.” This necessitates change.
    This economic reality prompted OpenAI to pursue a massive billion funding round that valued the company at an unprecedented billion. But even with a war chest of funds at its disposal, the fundamental challenge remains: OpenAI’s approach is dramatically more resource-intensive than DeepSeek’s.
    Beyond model training
    Another significant trend accelerated by DeepSeek is the shift toward “test-time compute”. As major AI labs have now trained their models on much of the available public data on the internet, data scarcity is slowing further improvements in pre-training.
    To get around this, DeepSeek announced a collaboration with Tsinghua University to enable “self-principled critique tuning”. This approach trains AI to develop its own rules for judging content and then uses those rules to provide detailed critiques. The system includes a built-in “judge” that evaluates the AI’s answers in real-time, comparing responses against core rules and quality standards.
    The development is part of a movement towards autonomous self-evaluation and improvement in AI systems in which models use inference time to improve results, rather than simply making models larger during training. DeepSeek calls its system “DeepSeek-GRM”. But, as with its model distillation approach, this could be considered a mix of promise and risk.
    For example, if the AI develops its own judging criteria, there’s a risk those principles diverge from human values, ethics or context. The rules could end up being overly rigid or biased, optimizing for style over substance, and/or reinforce incorrect assumptions or hallucinations. Additionally, without a human in the loop, issues could arise if the “judge” is flawed or misaligned. It’s a kind of AI talking to itself, without robust external grounding. On top of this, users and developers may not understand why the AI reached a certain conclusion — which feeds into a bigger concern: Should an AI be allowed to decide what is “good” or “correct” based solely on its own logic? These risks shouldn’t be discounted.
    At the same time, this approach is gaining traction, as again DeepSeek builds on the body of work of othersto create what is likely the first full-stack application of SPCT in a commercial effort.
    This could mark a powerful shift in AI autonomy, but there still is a need for rigorous auditing, transparency and safeguards. It’s not just about models getting smarter, but that they remain aligned, interpretable, and trustworthy as they begin critiquing themselves without human guardrails.
    Moving into the future
    So, taking all of this into account, the rise of DeepSeek signals a broader shift in the AI industry toward parallel innovation tracks. While companies continue building more powerful compute clusters for next-generation capabilities, there will also be intense focus on finding efficiency gains through software engineering and model architecture improvements to offset the challenges of AI energy consumption, which far outpaces power generation capacity. 
    Companies are taking note. Microsoft, for example, has halted data center development in multiple regions globally, recalibrating toward a more distributed, efficient infrastructure approach. While still planning to invest approximately billion in AI infrastructure this fiscal year, the company is reallocating resources in response to the efficiency gains DeepSeek introduced to the market.
    Meta has also responded,
    With so much movement in such a short time, it becomes somewhat ironic that the U.S. sanctions designed to maintain American AI dominance may have instead accelerated the very innovation they sought to contain. By constraining access to materials, DeepSeek was forced to blaze a new trail.
    Moving forward, as the industry continues to evolve globally, adaptability for all players will be key. Policies, people and market reactions will continue to shift the ground rules — whether it’s eliminating the AI diffusion rule, a new ban on technology purchases or something else entirely. It’s what we learn from one another and how we respond that will be worth watching.
    Jae Lee is CEO and co-founder of TwelveLabs.

    Daily insights on business use cases with VB Daily
    If you want to impress your boss, VB Daily has you covered. We give you the inside scoop on what companies are doing with generative AI, from regulatory shifts to practical deployments, so you can share insights for maximum ROI.
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    #rethinking #deepseeks #playbook #shakes #highspend
    Rethinking AI: DeepSeek’s playbook shakes up the high-spend, high-compute paradigm
    Join the event trusted by enterprise leaders for nearly two decades. VB Transform brings together the people building real enterprise AI strategy. Learn more When DeepSeek released its R1 model this January, it wasn’t just another AI announcement. It was a watershed moment that sent shockwaves through the tech industry, forcing industry leaders to reconsider their fundamental approaches to AI development. What makes DeepSeek’s accomplishment remarkable isn’t that the company developed novel capabilities; rather, it was how it achieved comparable results to those delivered by tech heavyweights at a fraction of the cost. In reality, DeepSeek didn’t do anything that hadn’t been done before; its innovation stemmed from pursuing different priorities. As a result, we are now experiencing rapid-fire development along two parallel tracks: efficiency and compute.  As DeepSeek prepares to release its R2 model, and as it concurrently faces the potential of even greater chip restrictions from the U.S., it’s important to look at how it captured so much attention. Engineering around constraints DeepSeek’s arrival, as sudden and dramatic as it was, captivated us all because it showcased the capacity for innovation to thrive even under significant constraints. Faced with U.S. export controls limiting access to cutting-edge AI chips, DeepSeek was forced to find alternative pathways to AI advancement. While U.S. companies pursued performance gains through more powerful hardware, bigger models and better data, DeepSeek focused on optimizing what was available. It implemented known ideas with remarkable execution — and there is novelty in executing what’s known and doing it well. This efficiency-first mindset yielded incredibly impressive results. DeepSeek’s R1 model reportedly matches OpenAI’s capabilities at just 5 to 10% of the operating cost. According to reports, the final training run for DeepSeek’s V3 predecessor cost a mere million — which was described by former Tesla AI scientist Andrej Karpathy as “a joke of a budget” compared to the tens or hundreds of millions spent by U.S. competitors. More strikingly, while OpenAI reportedly spent million training its recent “Orion” model, DeepSeek achieved superior benchmark results for just million — less than 1.2% of OpenAI’s investment. If you get starry eyed believing these incredible results were achieved even as DeepSeek was at a severe disadvantage based on its inability to access advanced AI chips, I hate to tell you, but that narrative isn’t entirely accurate. Initial U.S. export controls focused primarily on compute capabilities, not on memory and networking — two crucial components for AI development. That means that the chips DeepSeek had access to were not poor quality chips; their networking and memory capabilities allowed DeepSeek to parallelize operations across many units, a key strategy for running their large model efficiently. This, combined with China’s national push toward controlling the entire vertical stack of AI infrastructure, resulted in accelerated innovation that many Western observers didn’t anticipate. DeepSeek’s advancements were an inevitable part of AI development, but they brought known advancements forward a few years earlier than would have been possible otherwise, and that’s pretty amazing. Pragmatism over process Beyond hardware optimization, DeepSeek’s approach to training data represents another departure from conventional Western practices. Rather than relying solely on web-scraped content, DeepSeek reportedly leveraged significant amounts of synthetic data and outputs from other proprietary models. This is a classic example of model distillation, or the ability to learn from really powerful models. Such an approach, however, raises questions about data privacy and governance that might concern Western enterprise customers. Still, it underscores DeepSeek’s overall pragmatic focus on results over process. The effective use of synthetic data is a key differentiator. Synthetic data can be very effective when it comes to training large models, but you have to be careful; some model architectures handle synthetic data better than others. For instance, transformer-based models with mixture of expertsarchitectures like DeepSeek’s tend to be more robust when incorporating synthetic data, while more traditional dense architectures like those used in early Llama models can experience performance degradation or even “model collapse” when trained on too much synthetic content. This architectural sensitivity matters because synthetic data introduces different patterns and distributions compared to real-world data. When a model architecture doesn’t handle synthetic data well, it may learn shortcuts or biases present in the synthetic data generation process rather than generalizable knowledge. This can lead to reduced performance on real-world tasks, increased hallucinations or brittleness when facing novel situations.  Still, DeepSeek’s engineering teams reportedly designed their model architecture specifically with synthetic data integration in mind from the earliest planning stages. This allowed the company to leverage the cost benefits of synthetic data without sacrificing performance. Market reverberations Why does all of this matter? Stock market aside, DeepSeek’s emergence has triggered substantive strategic shifts among industry leaders. Case in point: OpenAI. Sam Altman recently announced plans to release the company’s first “open-weight” language model since 2019. This is a pretty notable pivot for a company that built its business on proprietary systems. It seems DeepSeek’s rise, on top of Llama’s success, has hit OpenAI’s leader hard. Just a month after DeepSeek arrived on the scene, Altman admitted that OpenAI had been “on the wrong side of history” regarding open-source AI.  With OpenAI reportedly spending to 8 billion annually on operations, the economic pressure from efficient alternatives like DeepSeek has become impossible to ignore. As AI scholar Kai-Fu Lee bluntly put it: “You’re spending billion or billion a year, making a massive loss, and here you have a competitor coming in with an open-source model that’s for free.” This necessitates change. This economic reality prompted OpenAI to pursue a massive billion funding round that valued the company at an unprecedented billion. But even with a war chest of funds at its disposal, the fundamental challenge remains: OpenAI’s approach is dramatically more resource-intensive than DeepSeek’s. Beyond model training Another significant trend accelerated by DeepSeek is the shift toward “test-time compute”. As major AI labs have now trained their models on much of the available public data on the internet, data scarcity is slowing further improvements in pre-training. To get around this, DeepSeek announced a collaboration with Tsinghua University to enable “self-principled critique tuning”. This approach trains AI to develop its own rules for judging content and then uses those rules to provide detailed critiques. The system includes a built-in “judge” that evaluates the AI’s answers in real-time, comparing responses against core rules and quality standards. The development is part of a movement towards autonomous self-evaluation and improvement in AI systems in which models use inference time to improve results, rather than simply making models larger during training. DeepSeek calls its system “DeepSeek-GRM”. But, as with its model distillation approach, this could be considered a mix of promise and risk. For example, if the AI develops its own judging criteria, there’s a risk those principles diverge from human values, ethics or context. The rules could end up being overly rigid or biased, optimizing for style over substance, and/or reinforce incorrect assumptions or hallucinations. Additionally, without a human in the loop, issues could arise if the “judge” is flawed or misaligned. It’s a kind of AI talking to itself, without robust external grounding. On top of this, users and developers may not understand why the AI reached a certain conclusion — which feeds into a bigger concern: Should an AI be allowed to decide what is “good” or “correct” based solely on its own logic? These risks shouldn’t be discounted. At the same time, this approach is gaining traction, as again DeepSeek builds on the body of work of othersto create what is likely the first full-stack application of SPCT in a commercial effort. This could mark a powerful shift in AI autonomy, but there still is a need for rigorous auditing, transparency and safeguards. It’s not just about models getting smarter, but that they remain aligned, interpretable, and trustworthy as they begin critiquing themselves without human guardrails. Moving into the future So, taking all of this into account, the rise of DeepSeek signals a broader shift in the AI industry toward parallel innovation tracks. While companies continue building more powerful compute clusters for next-generation capabilities, there will also be intense focus on finding efficiency gains through software engineering and model architecture improvements to offset the challenges of AI energy consumption, which far outpaces power generation capacity.  Companies are taking note. Microsoft, for example, has halted data center development in multiple regions globally, recalibrating toward a more distributed, efficient infrastructure approach. While still planning to invest approximately billion in AI infrastructure this fiscal year, the company is reallocating resources in response to the efficiency gains DeepSeek introduced to the market. Meta has also responded, With so much movement in such a short time, it becomes somewhat ironic that the U.S. sanctions designed to maintain American AI dominance may have instead accelerated the very innovation they sought to contain. By constraining access to materials, DeepSeek was forced to blaze a new trail. Moving forward, as the industry continues to evolve globally, adaptability for all players will be key. Policies, people and market reactions will continue to shift the ground rules — whether it’s eliminating the AI diffusion rule, a new ban on technology purchases or something else entirely. It’s what we learn from one another and how we respond that will be worth watching. Jae Lee is CEO and co-founder of TwelveLabs. Daily insights on business use cases with VB Daily If you want to impress your boss, VB Daily has you covered. We give you the inside scoop on what companies are doing with generative AI, from regulatory shifts to practical deployments, so you can share insights for maximum ROI. Read our Privacy Policy Thanks for subscribing. Check out more VB newsletters here. An error occured. #rethinking #deepseeks #playbook #shakes #highspend
    VENTUREBEAT.COM
    Rethinking AI: DeepSeek’s playbook shakes up the high-spend, high-compute paradigm
    Join the event trusted by enterprise leaders for nearly two decades. VB Transform brings together the people building real enterprise AI strategy. Learn more When DeepSeek released its R1 model this January, it wasn’t just another AI announcement. It was a watershed moment that sent shockwaves through the tech industry, forcing industry leaders to reconsider their fundamental approaches to AI development. What makes DeepSeek’s accomplishment remarkable isn’t that the company developed novel capabilities; rather, it was how it achieved comparable results to those delivered by tech heavyweights at a fraction of the cost. In reality, DeepSeek didn’t do anything that hadn’t been done before; its innovation stemmed from pursuing different priorities. As a result, we are now experiencing rapid-fire development along two parallel tracks: efficiency and compute.  As DeepSeek prepares to release its R2 model, and as it concurrently faces the potential of even greater chip restrictions from the U.S., it’s important to look at how it captured so much attention. Engineering around constraints DeepSeek’s arrival, as sudden and dramatic as it was, captivated us all because it showcased the capacity for innovation to thrive even under significant constraints. Faced with U.S. export controls limiting access to cutting-edge AI chips, DeepSeek was forced to find alternative pathways to AI advancement. While U.S. companies pursued performance gains through more powerful hardware, bigger models and better data, DeepSeek focused on optimizing what was available. It implemented known ideas with remarkable execution — and there is novelty in executing what’s known and doing it well. This efficiency-first mindset yielded incredibly impressive results. DeepSeek’s R1 model reportedly matches OpenAI’s capabilities at just 5 to 10% of the operating cost. According to reports, the final training run for DeepSeek’s V3 predecessor cost a mere $6 million — which was described by former Tesla AI scientist Andrej Karpathy as “a joke of a budget” compared to the tens or hundreds of millions spent by U.S. competitors. More strikingly, while OpenAI reportedly spent $500 million training its recent “Orion” model, DeepSeek achieved superior benchmark results for just $5.6 million — less than 1.2% of OpenAI’s investment. If you get starry eyed believing these incredible results were achieved even as DeepSeek was at a severe disadvantage based on its inability to access advanced AI chips, I hate to tell you, but that narrative isn’t entirely accurate (even though it makes a good story). Initial U.S. export controls focused primarily on compute capabilities, not on memory and networking — two crucial components for AI development. That means that the chips DeepSeek had access to were not poor quality chips; their networking and memory capabilities allowed DeepSeek to parallelize operations across many units, a key strategy for running their large model efficiently. This, combined with China’s national push toward controlling the entire vertical stack of AI infrastructure, resulted in accelerated innovation that many Western observers didn’t anticipate. DeepSeek’s advancements were an inevitable part of AI development, but they brought known advancements forward a few years earlier than would have been possible otherwise, and that’s pretty amazing. Pragmatism over process Beyond hardware optimization, DeepSeek’s approach to training data represents another departure from conventional Western practices. Rather than relying solely on web-scraped content, DeepSeek reportedly leveraged significant amounts of synthetic data and outputs from other proprietary models. This is a classic example of model distillation, or the ability to learn from really powerful models. Such an approach, however, raises questions about data privacy and governance that might concern Western enterprise customers. Still, it underscores DeepSeek’s overall pragmatic focus on results over process. The effective use of synthetic data is a key differentiator. Synthetic data can be very effective when it comes to training large models, but you have to be careful; some model architectures handle synthetic data better than others. For instance, transformer-based models with mixture of experts (MoE) architectures like DeepSeek’s tend to be more robust when incorporating synthetic data, while more traditional dense architectures like those used in early Llama models can experience performance degradation or even “model collapse” when trained on too much synthetic content. This architectural sensitivity matters because synthetic data introduces different patterns and distributions compared to real-world data. When a model architecture doesn’t handle synthetic data well, it may learn shortcuts or biases present in the synthetic data generation process rather than generalizable knowledge. This can lead to reduced performance on real-world tasks, increased hallucinations or brittleness when facing novel situations.  Still, DeepSeek’s engineering teams reportedly designed their model architecture specifically with synthetic data integration in mind from the earliest planning stages. This allowed the company to leverage the cost benefits of synthetic data without sacrificing performance. Market reverberations Why does all of this matter? Stock market aside, DeepSeek’s emergence has triggered substantive strategic shifts among industry leaders. Case in point: OpenAI. Sam Altman recently announced plans to release the company’s first “open-weight” language model since 2019. This is a pretty notable pivot for a company that built its business on proprietary systems. It seems DeepSeek’s rise, on top of Llama’s success, has hit OpenAI’s leader hard. Just a month after DeepSeek arrived on the scene, Altman admitted that OpenAI had been “on the wrong side of history” regarding open-source AI.  With OpenAI reportedly spending $7 to 8 billion annually on operations, the economic pressure from efficient alternatives like DeepSeek has become impossible to ignore. As AI scholar Kai-Fu Lee bluntly put it: “You’re spending $7 billion or $8 billion a year, making a massive loss, and here you have a competitor coming in with an open-source model that’s for free.” This necessitates change. This economic reality prompted OpenAI to pursue a massive $40 billion funding round that valued the company at an unprecedented $300 billion. But even with a war chest of funds at its disposal, the fundamental challenge remains: OpenAI’s approach is dramatically more resource-intensive than DeepSeek’s. Beyond model training Another significant trend accelerated by DeepSeek is the shift toward “test-time compute” (TTC). As major AI labs have now trained their models on much of the available public data on the internet, data scarcity is slowing further improvements in pre-training. To get around this, DeepSeek announced a collaboration with Tsinghua University to enable “self-principled critique tuning” (SPCT). This approach trains AI to develop its own rules for judging content and then uses those rules to provide detailed critiques. The system includes a built-in “judge” that evaluates the AI’s answers in real-time, comparing responses against core rules and quality standards. The development is part of a movement towards autonomous self-evaluation and improvement in AI systems in which models use inference time to improve results, rather than simply making models larger during training. DeepSeek calls its system “DeepSeek-GRM” (generalist reward modeling). But, as with its model distillation approach, this could be considered a mix of promise and risk. For example, if the AI develops its own judging criteria, there’s a risk those principles diverge from human values, ethics or context. The rules could end up being overly rigid or biased, optimizing for style over substance, and/or reinforce incorrect assumptions or hallucinations. Additionally, without a human in the loop, issues could arise if the “judge” is flawed or misaligned. It’s a kind of AI talking to itself, without robust external grounding. On top of this, users and developers may not understand why the AI reached a certain conclusion — which feeds into a bigger concern: Should an AI be allowed to decide what is “good” or “correct” based solely on its own logic? These risks shouldn’t be discounted. At the same time, this approach is gaining traction, as again DeepSeek builds on the body of work of others (think OpenAI’s “critique and revise” methods, Anthropic’s constitutional AI or research on self-rewarding agents) to create what is likely the first full-stack application of SPCT in a commercial effort. This could mark a powerful shift in AI autonomy, but there still is a need for rigorous auditing, transparency and safeguards. It’s not just about models getting smarter, but that they remain aligned, interpretable, and trustworthy as they begin critiquing themselves without human guardrails. Moving into the future So, taking all of this into account, the rise of DeepSeek signals a broader shift in the AI industry toward parallel innovation tracks. While companies continue building more powerful compute clusters for next-generation capabilities, there will also be intense focus on finding efficiency gains through software engineering and model architecture improvements to offset the challenges of AI energy consumption, which far outpaces power generation capacity.  Companies are taking note. Microsoft, for example, has halted data center development in multiple regions globally, recalibrating toward a more distributed, efficient infrastructure approach. While still planning to invest approximately $80 billion in AI infrastructure this fiscal year, the company is reallocating resources in response to the efficiency gains DeepSeek introduced to the market. Meta has also responded, With so much movement in such a short time, it becomes somewhat ironic that the U.S. sanctions designed to maintain American AI dominance may have instead accelerated the very innovation they sought to contain. By constraining access to materials, DeepSeek was forced to blaze a new trail. Moving forward, as the industry continues to evolve globally, adaptability for all players will be key. Policies, people and market reactions will continue to shift the ground rules — whether it’s eliminating the AI diffusion rule, a new ban on technology purchases or something else entirely. It’s what we learn from one another and how we respond that will be worth watching. Jae Lee is CEO and co-founder of TwelveLabs. Daily insights on business use cases with VB Daily If you want to impress your boss, VB Daily has you covered. We give you the inside scoop on what companies are doing with generative AI, from regulatory shifts to practical deployments, so you can share insights for maximum ROI. Read our Privacy Policy Thanks for subscribing. Check out more VB newsletters here. An error occured.
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