Google has filed a proposal outlining how it would remedy the antitrust violations its been accused of by the Department of Justice, after the DOJ called for Google to sell off Chrome and face restrictions that would prevent it from favoring its own search engine in Android. Judge Amit Mehta of the US District Court for the District of Columbia ruled in August that Google has violated Section 2 of the Sherman Act, and called Google a monopolist. Google said in the proposal filed on Friday night that it disagreed with the ruling but suggested ways to make its contracts with browser companies and Android device makers more flexible.In a blog post summarizing the filing, Googles VP of regulatory affairs Lee-Anne Mulholland wrote that the proposal would let browser companies like Apple and Mozilla continue to offer Google Search to their users and earn revenue from that partnership, while allowing them to have multiple default agreements across different platforms (e.g., a different default search engine for iPhones and iPads) and browsing modes. And browsers would be able to change their default search provider every 12 months. The proposal would also give device makers additional flexibility in preloading multiple search engines, and preloading any Google app independently of preloading Search or Chrome.Google said it plans to appeal the judges decision ahead of a hearing in April, and will submit a revised proposal on March 7. In the blog post, Mulholland called the DOJs proposal overboard, going on to write that it reflects an interventionist agenda and goes far beyond what the Courts decision is actually about our agreements with partners to distribute search.This article originally appeared on Engadget at https://www.engadget.com/big-tech/google-proposes-alternative-remedies-for-its-search-monopoly-after-doj-demands-radical-changes-185253526.html?src=rss

TeamGroup's CAMM2 technology aims to introduce a new memory standard.

Nvidia, AMD and TSMC have invested millions in a startup that may hold the key to faster chip connectivity to quench AI's thirst for bytes.

Previous reports suggested that the OnePlus Open 2 could be launched as early as January, February, or March.

Its hard to imagine a holiday season without A Charlie Brown Christmas. The 1965 broadcast has become a stapleetched into traditions across generations like decorating the tree or sipping hot cocoa.But this beloved TV special almost didnt make it to air. CBS executives thought the 25-minute program was too slow, too serious and too different from the upbeat spectacles they imagined audiences wanted. A cartoon about a depressed kid seeking psychiatric advice? No laugh track? Humble, lo-fi animation? And was that a Bible verse? It seemed destined to failif not scrapped outright.And yet, against all the odds, it became a classic. The program turned Peanuts from a popular comic strip into a multimedia empirenot because it was flashy or followed the rules, but because it was sincere.As a business professor who has studied the Peanuts franchise, I see A Charlie Brown Christmas as a fascinating historical moment. Its the true story of an unassuming comic strip character who crossed over into television and managed to voice hefty, thought-provoking ideaswithout getting booted off the air.Call from the blueThe Peanuts special came together out of a last-minute scramble. Somewhat out of the blue, producer Lee Mendelson got a call from advertising agency McCann-Erickson: Coca-Cola wanted to sponsor an animated Christmas special.Mendelson had previously failed to convince the agency to sponsor a Peanuts documentary. This time, though, he assured McCann-Erickson that the characters would be a perfect fit.Mendelson called up Peanuts comic strip creator Charles Sparky Schulz and told him he had just sold A Charlie Brown Christmasand they would have mere months to write, animate and bring the special to air.Charles Schulz drawing in the 1950s. [Photo: Roger Higgins/World Telegram & Sun via Library of Congress]Schulz, Mendelson and animator Bill Melendez worked fast to piece together a storyline. The cartoonist wanted to tell a story that cut through the glitz of holiday commercialism and brought the focus back to something deeper.While Snoopy tries to win a Christmas lights contest, and Lucy names herself Christmas queen in the neighborhood play, a forlorn Charlie Brown searches for the real meaning of Christmas. He makes his way to the local lot of aluminum trees, a fad at the time. But hes drawn to the one real treea humble, scraggly little thinginspired by Hans Christian Andersens fairy tale The Fir Tree.Jazzand the BibleThose plot points would likely delight the network, but other choices Schulz made were proving controversial.The show would use real childrens voices instead of adult actors, giving the characters an authentic, simple charm. And Schulz refused to add a laugh track, a standard in animated TV at the time. He wanted the sincerity of the story to stand on its own, without artificial prompts for laughter.Meanwhile, Mendelson brought in jazz musician Vince Guaraldi to compose a sophisticated soundtrack. The music was unlike anything typically heard in animated programming, blending provocative depth with the innocence of childhood.Most alarming to the executives was Schulzs insistence on including the heart of the Nativity story in arguably the specials most pivotal scene.When Charlie Brown joyfully returns to his friends with the spindly little tree, the rest of the Peanuts gang ridicule his choice. I guess I really dont know what Christmas is all about, the utterly defeated Charlie Brown sighs.Gently but confidently, Linus assures him, I can tell you what Christmas is all about. Calling for Lights, please, he quietly walks to the center of the stage.In the stillness, Linus recites the Gospel of Luke, Chapter 2, with its story of an angel appearing to trembling shepherds:And the angel said unto them, Fear not: for, behold, I bring you tidings of great joy, which shall be to all people.For unto you is born this day in the city of David a savior, which is Christ the Lord.Glory to God in the highest, and on earth peace, good will toward men, he concludes, picking up his security blanket and walking into the wings. The rest of the gang soon concludes Charlie Browns scrawny tree isnt so bad, after allit just needs a little love.When Schulz discussed this idea with Mendelson and Melendez, they were hesitant. For much of U.S. history, Protestant Christianity was the default in American culture, but in the years since World War II, society had grown somewhat more mindful of making room for Catholic and Jewish Americans. Unsure how to handle the shifting norms, many mainstream entertainment companies in the 1960s tended to avoid religious topics.The Bible thing scares us, CBS executives said when they saw the proofs of the special. But there was simply no time to redo the entire dramatic arc of the special, and pulling it was not an option, given that advertisements had already run.Fun and philosophyFortunately for the Peanuts franchise, when the special aired on December 9, 1965, it was an instant success. Nearly half of American households tuned in, and the program won both an Emmy and a Peabody Award. Schulz had tapped into something audiences were craving: an honest, heartfelt message that cut through the commercialism.Millions of viewers have continued to tune in to the shows annual rebroadcast for over 50 years on CBS and then ABCand now Apple TV+.When I was researching my spiritual biography of Schulz, A Charlie Brown Religion, one of my favorite finds was a 1965 letter from a Florida viewer, Betty Knorr. She praised the show for stressing the true meaning of the Christmas season at a time when the mention of God in general (is) being hush hushed.The magic of Schulzs work, though, is that it resonates across demographics and ideologies. Some fans find comfort in the shows gentle message of faith, while others embrace it in a purely secular way.Simple but poignant, Schulzs art and gentle humor can do two things. They can act as safe entry points for some pretty hefty thoughtsbe they psychiatric, cultural or theological. Or Peanuts cartoons can simply be heartwarming, festive entertainment, if thats what you want.Today, both the Peanuts empire and the Christmas industry are thriving. Back in the 1960s, commercial realities almost derailed Schulzs special, yet those same forces ultimately ensured its broadcast. The result is a lasting touchstone of innocence, hope, and belief.Stephen Lind is an associate professor of clinical business communication at the University of Southern California.This article is republished from The Conversation under a Creative Commons license. Read the original article.

There are many reasons why sometimes kids are left to play alone or entertain themselves. Oftentimes the babysitter would be a phone or tablet or any gadget but of course these are mostly passive activities and they cannot totally interact with it. Of course actual contact with human beings would be the most ideal but for those that are not able to always do so, an interactive educational and entertainment tool would be the next best thing.Designer: Onurhan DemirThe TED-I is an AI-powered Teddy Bear concept that is meant to be a friend, menter, and teacher to the child that its baby-sitting if there are no available adults at the moment. It is equipped with different features to help engage with the child and recognize their potential early on. The child is also able to interact back with the bear because of the features so they dont feel that theyre just alone with the device.The bear is equipped with two microphones on its ears so it can detect sounds around it, including when the child talks. One of its eyes has a projector lens that can project images and videos onto surfaces while the other eye has a camera that can detect user and environmental movements. It can also record and stream live video for the parents if theyre not there. On the cheeks, there are two speakers so the child can listen to music and to the videos audio. Theres also an LED screen on its mouth so you can see real-life mouth movements and expressions while the artificial heart on its chest also expresses emotions through the different colors. It has a wireless charging pillow when you need to it to rest and recharge. Its an interesting concept if the child (or adult) is not afraid of android bears that might eventually become their overlord. While its meant to be a childs more interactive babysitter, the parents can also enjoy it with their children like watching movies together and listening to music while talking. The post AI-powered teddy bear concept is an interactive babysitter for kids first appeared on Yanko Design.

A new claim says that any iPhone that can run iOS 18 will also work with iOS 19, but some older iPad models won't get iPadOS 19.While Apple Intelligence dominates the feature list, iOS 19 will be compatible with older iPhones also.French website iPhoneSoft, citing anonymous sources from within Apple, says that any iPhone model that can currently run iOS 18 will also be able to run iOS 19 when it arrives in late 2025.This includes the iPhone XR from 2018, along with the second-generation iPhone SE from 2020 and later. Here's the full list of compatible iPhone models: Rumor Score: Likely Continue Reading on AppleInsider | Discuss on our Forums

With every game that launches and meets (or surpasses) expectations, there will always be several other titles that fall short. They could have the most extensive marketing budget, the sharpest visuals or the biggest IP behind them things just dont come together in a compelling, much less enjoyable way. Of course, other titles could disappoint simply due to trends and being in the wrong place at the wrong time. Regardless, here are our 15 picks for the most disappointing games of 2024.Star Wars OutlawsAs iffy as certain things looked before launch, there was still some hope for Star Wars Outlaws from Massive Entertainments involvement alone. The Reputation and Wanted system, more organic exploration, and focus on single-player were all the right moves, but it didnt land for consumers. Those who took the plunge suffered numerous bugs and issues with movement, combat, AI, stealth, and so on. Its a better game now, but Outlaws still needs work.Suicide Squad: Kill The Justice LeagueEven with successes like Helldivers 2, this year just wasnt it for live-service titles. However, the negative response to Suicide Squad: Kill the Justice League began well prior, with many criticizing the looter shooters format. The release sadly did nothing to rise to the occasion, featuring a horrendous story that falls off a cliff, insufferable characters, and the same dreary games-as-a-service mission structure seen hundreds of times before. With a $200 million impact on Warner Bros. Discoverys revenue, Suicide Squad clearly didnt meet expectations.Skull and BonesAlleged reboots, high-profile departures, constant delays, and a ballooning budget Ubisofts Skull and Bones had all the key ingredients for a potential disaster. Adding in all the live-service staples like seasons, always-online gameplay, a focus on multiplayer, and whatnot hastened the games doom (calling it a quadruple-A title also didnt help). With player numbers reportedly coming in at less than a million around launch, it was a failure before it even got started.Planet Coaster 2Incredible visuals and the studios penchant for attention to detail did little to make a difference for Planet Coaster 2, which is, by all accounts, a hotly awaited sequel, that much more palatable. The awful UI, pathing issues, lackluster pools, awful characters and various bugs were just too significant to ignore, even with the better campaign. Frontier has rolled out improvements, and it will likely excel in the long run, but for now, Planet Coaster 2 is an underwhelming ride.Farming Simulator 25After the failure of Farming Simulator 23 (at least on Nintendo Switch), Farming Simulator 25 marked a return for the franchise to consoles and PC. It shipped with extensive bugs, an annoying user interface, jarring physics, and multitudes of other issues that remain. Thats on top of the unoptimized performance on PC, which hinders the otherwise strong environmental effects and textures. Mods will likely make it a better experience over time but at this point, fans would appreciate a strong title out of the gate (which certainly applies to our next choice).Starfield: Shattered SpaceStarfield had its share of mixed impressions after launching last year and Shattered Space seemed like the perfect opportunity to address many issues while offering a fresh slate. However, the hand-crafted planet of Varuunkai delivered the most rudimentary content and barren surroundings to go with lackluster characters and story-telling. Even the intriguing gravity anomalies barely appear after a point.A Quiet Place: The Road AheadI was excited about Stormind Games first-person horror, especially with how it leveraged the films and their mechanics. Unfortunately, A Quiet Place: The Road Ahead is a hugely linear, highly scripted experience with bizarre AI, questionable design decisions, and a predictable story that fails to really leverage its endearing characters.ConcordSonys biggest first-party failure in years, Concord was seemingly doomed from its first proper reveal, especially when the hero shooter elements became apparent. After a beta with abysmal numbers, it would launch to middling reviews and reportedly sold only 25,000 copies. Sony initially pulled the title from sale and shut down servers before eventually shuttering it and Firewalk Studio.Rise of the RoninDirector Fumihiko Yasuda revealed around June that Rise of the Ronin was Koei Tecmos best-selling game so far, with the publisher even reporting higher sales than Nioh. Thats all great, but the game itself fell short of what we expected in terms of open-world activities and storytelling. At least the combat remains enjoyable, and Team Ninja has provided some extensive post-launch content for free.Dragon Age: The VeilguardThe first Dragon Age title in ten years was bound to have astronomical expectations, especially with all the rumors and reports of reboots. Combat was sharp despite pivoting to a real-time hack-and-slash approach and the environments are gorgeous, without a doubt. Its everything else that either whelmed or disappointed, from the uneven characterization and writing to the mission structure. Though it wasnt BioWares worst, its far from being its best.Call of Duty: Black Ops 6Significant improvements over last years game dont excuse Call of Duty: Black Ops 6 from disappointing in other ways. Despite a superior campaign, its story ultimately felt flat (and continued the same cliffhanger approach), while multiplayer fell short with its map design. Zombies is surprisingly good despite some balance issues, and while the overall experience classifies as good, its nowhere near the series heights.Unknown 9: AwakeningTheres always some skepticism when a developer gets ahead itself and plans out an entire universe for its IP before the first game even launches. Unfortunately, Unknown 9: Awakening loaded its bland premise with dull writing and boring combat, while various bugs and performance issues weighed even heavier. Suffice it to say that with an all-time peak concurrent player count of 285 on Steam at launch, Unknown 9: Awakening failed to meet any expectations heaped on it.MultiVersusFrom promising platform fighter to being pulled and relaunching earlier this year in a worse form, MultiVersus has had quite the journey. Its hard to pinpoint all the issues, be it the sheer lack of quality-of-life features at launch or how underwhelming Rifts felt after they finally went live, but above all else, the feel and fluidity from the open beta felt like it was missing. And unfortunately, Player First Games hasnt been able to capture the magic ever since.XDefiantInitially revealed as part of the Tom Clancy series, XDefiant would become a standalone entity while still crossing over with the publishers various other titles. However, despite some responsive shooting, it couldnt match the features and content of other free-to-play shooters at launch. Various issues like network performance also affected it, causing a sharp downturn. Maybe theres still time to right the ship, but based on the companys other live-service endeavors, XDefiants days could be numbered.Outcast: A New BeginningDeveloping a sequel to a niche title from the late 90s is unusual on its own, but perhaps Outcast: The New Beginning could cater to long-time fans. What it offered was a massive world with nothing exciting, loading up players with menial tasks and awful writing. Appealing as it may be for those seeking more old-school-style titles, A New Beginning felt more like an awkward continuation for a cult-classic series.

Artificial intelligence (AI) is reshaping the way we approach everyday tasks, simplifying processes, and unlocking new levels of efficiency. AI tools enhance productivity and offer innovative solutions to a wide range of challenges, from managing daily routines to improving communication and decision-making. Whether its automating repetitive chores, organizing schedules, or personalizing experiences, AI is becoming an essential part of everyday life, making tasks smarter and more efficient. This article explores 25 AI tools designed to help improve productivity across various aspects of daily life.ChatGPTChatGPT, developed by OpenAI, is an advanced AI chatbot designed to facilitate natural conversations. It can assist with answering queries, brainstorming ideas, and drafting content. Businesses use ChatGPT for customer support automation, creating personalized communication, and streamlining documentation. Key features include its ability to understand and generate human-like text, making it highly versatile. However, its reliance on internet connectivity and occasional inaccuracies in complex queries can be limitations.GrammarlyGrammarly is an AI-powered writing assistant that enhances the clarity, correctness, and tone of text. Professionals widely use it for drafting error-free emails, reports, and marketing materials. Grammarly offers real-time grammar checks, vocabulary suggestions, and tone adjustments. The tools seamless integration with browsers and productivity apps is a significant strength, though its premium features come at a cost.Otter.aiOtter.ai is an AI-powered transcription tool designed to convert spoken words into written text. Its widely used in meetings, lectures, and interviews to create accurate transcripts. Otter.ai supports real-time transcription and speaker identification, making it a favorite among remote teams. While it saves time and ensures documentation accuracy, its transcription accuracy can vary with accents and background noise.MeetGeekMeetGeek is an AI meeting assistant that automatically video records, transcribes, summarizes, and provides key insights from every meeting.Trello with ButlerTrello, paired with its AI-powered automation tool Butler, revolutionizes task management. Trello helps teams organize projects through visual boards, while Butler automates repetitive tasks like setting due dates and sending reminders. Businesses use Trello for project tracking and team collaboration. Its intuitive interface is a strength, but complex projects may require integration with other tools.CalendlyCalendly simplifies scheduling by integrating with calendars to automate meeting bookings. It eliminates the back-and-forth emails to find suitable times. Calendly is highly effective for client meetings and interviews. Its ability to integrate with apps like Zoom and Salesforce is a plus, though its free version lacks some advanced features.JasperJasper is an AI-powered content generation tool designed to create high-quality marketing copy, blog posts, and social media content. It helps marketers and writers significantly speed up the content creation process by providing suggestions, drafting text, and even generating complete articles. Jaspers ability to produce engaging content in various styles and tones is a major strength, making it ideal for businesses looking to scale their content production. However, while Jasper can generate high-quality content quickly, users often need to edit the output to ensure consistency in tone and voice, especially when working on longer or more nuanced pieces. Despite this, it remains a popular choice for marketers seeking efficiency and fresh ideas for their content.Notion AINotion AI is integrated into the Notion productivity platform, automating tasks like writing, summarizing notes, and brainstorming ideas. Teams use Notion AI for collaborative document editing, note-taking, and project management, benefiting from its ability to generate content ideas or provide quick summaries. The integration with Notions rich ecosystem of toolslike databases, tasks, and calendarsmakes it easy for teams to centralize their workflows. However, the AI-generated content sometimes lacks depth and may need further refinement, especially when tackling complex topics. Despite this limitation, Notion AI is a powerful assistant for teams seeking to streamline documentation and enhance collaboration.Zoom AI CompanionZoom AI Companion offers advanced features to enhance virtual meetings, including transcription, sentiment analysis, and automated summaries. This AI-powered tool is particularly useful for remote teams looking to improve meeting efficiency by capturing key takeaways and action items without needing to take extensive notes. The sentiment analysis feature can help teams understand the mood or tone of the conversation, making it easier to gauge the effectiveness of communication. However, while Zoom AI Companion improves productivity, it may not always capture every nuance of a conversation, and errors in transcription or sentiment detection can occur, especially in complex or fast-paced discussions.Canva with Magic ResizeCanva integrates AI with tools like Magic Resize, allowing marketers and designers to quickly create and adapt graphic designs for various platforms. Magic Resize automatically adjusts the size and proportions of designs, making it easy to repurpose content for different social media channels, presentations, or marketing materials. Canvas intuitive design tools and customizable templates make it accessible to both professional designers and beginners. However, the free version of Canva offers limited premium templates and features, which may restrict users who need more advanced options. Despite this, the combination of AI-driven design suggestions and ease of use makes Canva an ideal choice for creating visually appealing content quickly.Monday.com with AI AssistanceMonday.com incorporates AI to enhance project management capabilities, automating tasks like prioritization and progress tracking. Businesses use this tool to optimize workflows, allocate resources more effectively, and gain actionable insights into project performance. The AI features can analyze project data to suggest improvements and help teams stay on schedule. Monday.coms intuitive dashboards and customization options are key strengths, allowing teams to tailor the platform to their needs. However, advanced features like detailed analytics are only available through premium plans, which can be a limiting factor for smaller teams or businesses on a budget. Still, the platform remains an effective tool for enhancing project management and team collaboration.Figma with AI PluginsFigma integrates AI plugins to streamline design processes, particularly for UI/UX designers working on collaborative design projects. These AI-driven features include auto-layouts, content generation, and real-time design suggestions, which help save time and enhance the overall design workflow. Figmas cloud-based platform makes it easy for multiple designers to collaborate on the same project simultaneously, increasing productivity and creativity. However, its reliance on internet connectivity can be a limitation for teams needing to work offline, as they will lose access to AI features and collaboration tools. Despite this, Figmas powerful design tools, combined with AI enhancements, make it a popular choice for design teams looking to optimize their workflows and improve collaboration.Adobe SenseiAdobe Sensei is an AI platform embedded into Adobes suite of creative tools, including Photoshop, Illustrator, and Adobe Experience Cloud. It leverages machine learning to enhance image recognition, automate mundane tasks, and generate personalized content suggestions, making it a valuable asset for designers, marketers, and content creators. Sensei can help streamline workflows, speeding up tasks such as object removal, automatic tagging, and image enhancement, all based on user behavior and data analysis. While it provides powerful features, users may need substantial training to harness its full potential, especially as it integrates advanced AI functions, which could be overwhelming for beginners or those unfamiliar with AI tools.Salesforce EinsteinSalesforce Einstein is an AI-powered feature integrated into Salesforces Customer Relationship Management (CRM) platform. It enables users to leverage predictive analytics, automate workflows, and receive personalized insights to boost sales and customer engagement. By analyzing vast amounts of data, Einstein can prioritize leads, forecast sales trends, and recommend actions to enhance customer relationships. This makes it a valuable tool for sales teams looking to optimize their efforts and close deals more efficiently. However, implementing Einstein requires a more complex setup and customization, which can be challenging for smaller teams or businesses without dedicated resources for deployment and training.Slack GPTSlack GPT integrates generative AI directly into Slacks communication platform, allowing teams to summarize conversations, generate actionable insights, and automate repetitive tasks. It enhances the productivity of teams by simplifying workflows and improving the flow of information within a company. By analyzing conversations, Slack GPT can help prioritize messages, summarize lengthy threads, and suggest actionable next steps, helping teams stay organized and responsive. However, its effectiveness heavily depends on how well it is integrated and how users adopt the tool. Misuse or incorrect integration may reduce its potential, and proper onboarding and training are essential to ensure teams fully benefit from Slack GPTs capabilities.HubSpot (AI Tools)HubSpot is a comprehensive inbound marketing, sales, and service software that integrates AI to enhance various aspects of marketing automation, customer segmentation, and sales forecasting. With AI-driven features like personalized email campaigns, predictive lead scoring, and customer behavior analysis, HubSpot enables businesses to engage customers more effectively and efficiently nurture leads. The AI tools offer actionable insights, helping businesses fine-tune their marketing strategies and increase conversions. However, while HubSpots features are robust, its pricing structure can become expensive, especially when businesses opt for more advanced tools and integrations, making it more suitable for medium to large organizations. Despite the cost, its all-in-one platform remains highly regarded for automating and streamlining customer relationship management.CrystalCrystal uses AI to provide insights into personality traits and communication preferences, helping individuals and teams communicate more effectively. By analyzing publicly available data, Crystal offers personalized recommendations on how to approach conversations, whether with colleagues, clients, or partners. Sales and HR teams benefit from this tool by tailoring their communication style to better connect with others and close deals or hire candidates more effectively. However, the tools reliance on data accuracy can be a limitation, as the insights it generates are only as good as the information it analyzes. Inaccurate or insufficient data can lead to suboptimal recommendations, making it important to ensure that data sources are reliable.SuperhumanSuperhuman is a highly efficient email management tool that uses AI to streamline inbox organization and communication. It incorporates features like smart categorization, predictive replies, and advanced search functions to help users process emails faster and more effectively. Executives and professionals who require quick and efficient email management often turn to Superhuman for its speed and the ability to cut down on time spent managing emails. However, its premium pricing is a significant barrier for many users, as it can be costly compared to other email management tools. Despite this, its blend of powerful AI tools and user-friendly interface has made it a favorite among high-performing individuals who value efficiency and speed.Clockify (AI Timesheets)Clockify is an AI-powered time-tracking tool designed to help businesses and individuals track working hours and productivity with ease. The tool automates the process of creating accurate timesheets, making it easier for businesses to handle billing and analyze employee productivity. Clockify is particularly valuable for freelancers and teams that need to log work hours for invoicing or project management purposes. Its simplicity and ease of use are key strengths, making it accessible to a wide range of users. However, while the basic features are free, advanced functionalities such as reporting and detailed analytics are only available with paid plans, limiting its accessibility for those on a budget.DescriptDescript is an AI-driven tool designed for video and audio editing, making it a popular choice for podcasters, content creators, and media professionals. It offers powerful transcription features that automatically convert audio and video files into text, which can then be edited just like a text document. This makes editing much easier and more intuitive, as users can cut, paste, and rearrange the content with minimal effort. Descript also supports audio and video publishing, which streamlines the workflow for creators. However, exporting large files can be time-consuming, particularly for longer recordings or high-quality media, which can impact its efficiency for users working with extensive content. Despite this, Descripts ease of use and AI capabilities make it a valuable tool for content creation.ClickUp (AI Writing Assistant)ClickUp helps streamline task management and project coordination by automating the creation of tasks, reports, and workflow optimizations. Teams can use this tool to save time by automatically generating project descriptions, to-do lists, and status updates, ensuring consistency and reducing the manual effort required for managing projects. The AI Writing Assistant is particularly useful for teams working on collaborative projects, as it can help create clear and concise communication. The flexibility of ClickUp allows for a wide range of customization, but the tools features can be overwhelming for new users, leading to a steep learning curve. Despite this, ClickUps combination of AI features and flexibility has made it popular among businesses that require comprehensive project management solutions.SaplingSapling is an AI-powered tool designed to enhance customer support by providing real-time grammar checks and suggesting responses to agents. It helps businesses improve both the speed and quality of customer interactions by automatically correcting language errors and offering tailored responses based on context. Integrated with CRM tools, Sapling ensures that responses are consistent with customer data, improving the overall customer experience. However, Saplings functionality is limited to English, which may restrict its usefulness for global teams or those working in multilingual environments. Despite this, it is a valuable tool for improving communication efficiency, especially in customer service roles where quick, clear, and professional responses are crucial.TidioTidio uses AI-powered chatbots to automate customer support and lead generation, making it an attractive solution for small businesses looking to enhance user engagement. The tool allows businesses to set up automated conversations, answering frequently asked questions and engaging with potential leads, which helps free up customer service agents for more complex issues. Tidios free plan provides a good starting point for small businesses, but advanced features like advanced automation, reporting, and integrations require a paid subscription. Despite this, its ease of use and affordability for smaller businesses make it an appealing option for automating customer interactions and improving overall efficiency.Canva DocsCanva Docs brings AI-powered design features to document creation, enabling teams to quickly generate visually appealing reports, presentations, and other documents. Canvas design-centric approach ensures that content created in Canva Docs is not only functional but also professional-looking, with easy-to-use templates and layout options. The tool is especially popular among marketing teams, content creators, and businesses looking to create branded documents in a short amount of time. However, while Canva Docs excels in visually-driven content, it is less suited for data-heavy documents or reports that require complex tables and analytics. For teams focused on creating aesthetically appealing content, though, it provides a powerful and efficient solution.Miro AIMiro AI integrates AI into its collaborative whiteboarding platform to enhance teamwork and brainstorming sessions. With features like automated diagram generation and real-time idea clustering, Miro helps teams better organize and visualize their thoughts, making it ideal for remote collaboration and creative problem-solving. Miros intuitive interface makes it easy for teams to start collaborating instantly, even if they have no prior experience with whiteboarding tools. However, some of the AI-powered features are still in beta, meaning that users may experience occasional bugs or limitations in functionality. Despite this, Miros AI capabilities, combined with its flexibility and collaborative focus, make it a strong choice for teams looking to enhance remote work and idea sharing.ConclusionAI is rapidly spreading its influence across every field, revolutionizing industries from healthcare to finance, marketing to design. Its ability to automate tasks, analyze data, and enhance decision-making is transforming how businesses operate, making processes faster, more efficient, and smarter. However, the key to unlocking AIs full potential lies in understanding how to use it effectively. The most efficient way to complete a task today is not just through hard work, but by leveraging AI tools that can accelerate performance, improve accuracy, and open up new possibilities. Embracing AI in your workflow isnt just a trendits the future of efficiency and innovation.The post Top 25 AI Tools to Increase Productivity in 2025 appeared first on MarkTechPost.

Designing antibodies with high specificity and binding affinity to diverse therapeutic antigens remains a significant challenge in drug development. Current methods struggle to effectively generate complementarity-determining regions (CDRs) responsible for antigen binding, especially the highly variable heavy chain CDR3 (HCDR3). These difficulties are mainly due to poor generalization of the already existing computational models to the experimental validation of their designs, inefficiency in optimizing leads, etc. Addressing these challenges will drive the advancement of therapeutic antibody engineering to advance and accelerate the formulation of effective treatments.The current computational models, like ProteinMPNN and AntiFold, use generative approaches to predict sequences that fit particular antibody structures. Although these systems have excellent in silico performance, their practical application is limited by the absence of extensive experimental validation. Additionally, they suffer from designing several CDR regions as a coherent approach toward attaining antigen specificity. They greatly require curated datasets, which are real constraints on their ability to scale to new targets-antigens and prove inadequate in performance aspects compared to baselines set up.Absci Bio Releases IgDesign: A Deep Learning Approach Transforming Antibody Design with Inverse Folding. IgDesign addresses the above limitations through a novel generative framework tailored to antibody design. It incorporates contextual inputs such as antigen sequences and antibody framework (FWR) sequences to create optimized CDR3 (HCDR3) and complete heavy-chain CDRs (HCDR123). Structure-aware encoder and sequence decoder, inspired by LM-design but specially adapted for antibody functions. It further distinguishes itself by the ability to design high-affinity binders validated through extensive in vitro testing across eight therapeutic antigens. The breakthrough enhances scalability, improves generalizability, and achieves experimental success rates that set a new standard for therapeutic antibody design.The researchers curated datasets from SAbDab and PDB, ensuring the inclusion of strong antigen-specific holdouts to eliminate the possibility of data leakage. The model was pre-trained on a general protein dataset and then fine-tuned on antibody-antigen complexes. Antibody sequences were generated sequentially to maintain coherence between interdependencies of regions; for each antigen, 100 HCDR3 and 100 HCDR123 were generated and tested. The sequences were progressed through an extensive wet-laboratory protocol that included cloning of the sequences into E. coli, expression within these cells, and high throughput SPR screening designed to support the confirmation of binding kinetics and affinities. A robust set of HCDR3 sequences from the training dataset was used as controls to measure performance, a distinct reference point for proving the utility of IgDesign.IgDesign showed consistent superior performance of designed antibodies across all different antigens. Experiments in vitro showed that designs of HCDR3 had significantly higher binding rates than baselines for seven out of eight tested antigens, and the design of HCDR123 outperformed the baseline for four of them. The produced antibodies are bound at affinities close to or better than those of clinically validated reference antibodies for targets such as CD40 and ACVR2B. Such findings underline the potential of IgDesign to generalize proficiently and design superior antibodies, which opens up transformative possibilities in therapeutic antibody development.This work represents a significant step for antibody design in that IgDesign marries high computational accuracy with empirical evidence to create a unified, streamlined process. As a result of success in antigen-specific binder construction exhibiting very high affinity, this advance challenges major bottlenecks in drug discovery. The framework not only facilitates lead optimization but also paves the way for de novo antibody design, significantly advancing the field of drug discovery.Check out the Paper and Code. All credit for this research goes to the researchers of this project. Also,dont forget to follow us onTwitter and join ourTelegram Channel andLinkedIn Group. Dont Forget to join our60k+ ML SubReddit. Aswin Ak+ postsAswin AK is a consulting intern at MarkTechPost. He is pursuing his Dual Degree at the Indian Institute of Technology, Kharagpur. He is passionate about data science and machine learning, bringing a strong academic background and hands-on experience in solving real-life cross-domain challenges. [Download] Evaluation of Large Language Model Vulnerabilities Report (Promoted)