Nature, Published online: 08 January 2025; doi:10.1038/s41586-024-08400-1Serine 118 phosphorylation drives conformational changes through the disruption of hydrophobic interactions between aromatic-rich clusters, showing how hydrophobic mutations can restore oestrogen receptor-mediated transcription.

Nature, Published online: 08 January 2025; doi:10.1038/s41586-024-08405-wThis study presents cryogenic electron microscopy structural analysis of a diversity-generating retroelement (DGR) reverse transcription system from Bordetella bacteriophage, with results indicating that RNA surrounding the template controls reverse transcription through mechanisms that are conserved across distant taxa.

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Since adopting a live-service model, Call of Duty has introduced numerous systems for unlocking exclusive cosmetic rewards, catering to both free and premium players. Among these, the Battle Pass popularized by free-to-play games has become a central feature, offering tiered rewards.

Pokemon GO announced the debut of Rookidee, Corvisquire, and Corviknight on January 21 at the Steely Resolve event. Pokemon GO players have been waiting for the addition of the Corviknight evolutionary line for some time, and now it comes to increase the number of Galar Pokemon available in the game.

The Grand Theft Auto franchise is predominantly known for its missions and driving experience, with every installment featuring a wide range of vehicles to choose from. Aircraft have been in the series for more than 2 decades. However, they were often sidelined in previous entries. In GTA Online, it's a different story.

Spotify's Playlist in a Bottle feature is back, and your 2024 music time capsule is waiting to be unveiled.

Assassin's Creed Shadows has been delayed again with the next entry in the behemoth series pushed back to March 20, 2025.

GameStop has reportedly uploaded a range of Nintendo Switch 2 accessory listings to its site.

Tippett Studios takes us behind the scenes and shows us just how incredible the process was of bringing Mama Crab to life in episode 6 of Star Wars: Skeleton Crew. The talented team at Tippett Studios used a combination of practical and digital effects to craft the character, bringing her into the world with such intricate detail that she seemed to be born into the Star Wars universe. From initial concept art to motion capture, Tippett Studios used its great expertise in making a creature feel real, emotional, and engaging.Planning was very intensive and involved teamwork with the animators, visual effects artists, and directors to achieve a seamless execution of Mama Crabs movements and interaction with the environment. The work of Tippett in Skeleton Crew best defines the modern VFX character creation art as applied in the storytelling of the Star Wars universe.The post Skeleton Crew Bringing Mama Crab to Life: Behind the Scenes appeared first on Vfxexpress.