Nature, Published online: 29 January 2025; doi:10.1038/s41586-024-08498-3Caspase recruitment domains (CARDs) are present in defence systems that protect bacteria against phage, where the bacterial CARD domain is essential for protease-mediated activation of bacterial gasdermins that promote cell death.

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Re @IOInteractive is seeking a process-orientedLead Character Artistwith AAA experience to lead the team of Character Artists. If you're passionate about creating high-quality, realistic characters in the fantasy genre, this role is for you! Apply today: https://bit.ly/3PRmB13#sponsored #ad #80LevelJobs

Gal Ravid-Tal shared the process of creating the Extraction project in Unreal Engine 5.4 using Lumen, explaining how the dynamic lighting approach enhances the ice and snow shaders and how detailed motion blur was effectively captured.Read here: https://80.lv/articles/snow-shader-with-a-subsurface-profile-created-in-unreal-engine-5-4-with-lumen/#unrealengine

SmokeChimney, Leartes StudiosTake a look at this incredible VFX Smoke Pack for Unreal Engine by Leartes Studios, which will help you create lifelike complex environments.You can use the tools in the latest engine version, Unreal Engine 5, and add depth and atmospheric effects to your 3D scenes, whether you work in film, video game, or art industry. The pack includes three types of visual effect setups:Fog;SmokeChimney;SmokeToxic.While Fog and SmokeChimney offer a realistic representation of smokey effects, which you can use in the scenes showing realistic locations and conditions, SmokeToxic will help you add a fantasy or steampunk touch to the scene.Fog, Leartes StudiosSmokeToxic, Leartes StudiosLeartes Studios specializes in helping 3D artists to create immersive artworks with high-quality 3D assets and provides a wide range of services, covering multiple stages of the pipeline, including modeling, texturing, rigging, lighting, and showcasing.Get the Smoke VFX Pack here anddont forget to join our 80 Level Talent platform and our new Discord server, follow us on Instagram, Twitter, LinkedIn, Telegram, TikTok, and Threads, where we share breakdowns, the latest news, awesome artworks, and more.Source link The post Check Out This Fantastic VFX Smoke Pack for Unreal Engine 5 appeared first on CG SHARES.

Weight is an important element in 3D, which helps animation be more realistic. Vincent Wedde added some flair to his stomping knight animation with stylized anime-style dust VFX.With little rocks flying left and right from the ground, Wedde combined 3D with 2D in an interesting visual using Unity.If youre curious about the artists other works, be sure to visit his X/Twitter.Wedde has worked on over 15 games, so he has a lot to share. You can see his experience on his website.Want more VFX made with Unity? Check out Pawel Margaczs poison projectile, Gregory Silvas Zelda-like effect, and DoubleCats cool VFX inspired by Honkai: Star Rail.Also, join our 80 Level Talent platformand ournew Discord server, follow us onInstagram,Twitter,LinkedIn,Telegram,TikTok, andThreads,where we share breakdowns, the latest news, awesome artworks, and more.Source link The post Impactful Anime-Style Stomp Dust VFX Created with Unity appeared first on CG SHARES.

New Presidential administrations almost always mean a new agenda for the Federal Communications Commission. As a prime example of this, the new FCC Chair Brendan Carr has struck down a Biden-era proposal that would have limited landlords' ability to make tenants accept mandatory internet service through a single bulk provider. Since the proposal has been shot down, there's nothing keeping building owners from forcing their tenants to pay for internet service they neither want nor need.As reported by Ars Technica, Carr framed his decision as a win for consumers and claimed that the previous proposal would have increased increased internet costs for tenants. He also condemned the proposal as "regulatory overreach" and promised to undo more of the FCC's prior agenda.However, the now-defunct proposal was not a ban on landlords' ability to offer bulk internet services; it simply gave tenants the ability to refuse the service. That was opposed by housing industry lobby groups, who in turn praised Carr's decision for allowing renters "to reap the benefits of bulk billing." Cable industry lobbyists--including representatives of Comcast, Charter, and Cox--were also in favor of Carr's action.Continue Reading at GameSpot

The long-running tabletop mech game BattleTech has spawned numerous video games, including MechWarrior, MechAssault, and 2018's BattleTech, but if you've ever wanted to get into the board game that started it all, now is the perfect time. The game recently celebrated its 40th birthday with a new 40th Anniversary Edition of the core box, and various new expansions have launched in the months since, including new mech minis, source books, and more. The latest new releases include the BattleTech: Mercenaries expansion and a bunch of standalone mech and vehicle minis to add to your tabletop sessions. BattleTech Mercenaries $75 The BattleTech: Mercenaries box includes eight BattleTech miniatures and four vehicle miniatures, plus a gameplay primer, rulebook, punch-out tokens, maps, pilot cards, Battlefield Support cards, and a premade campaign to play through. Note that this expansion requires the BattleTech: Game of Armored Combat 40th Anniversary Edition to play. See at Amazon Along with the new Mercenaries box, you can also expand your BattleTech collection with a batch of new miniatures. There are five packs available now, each of which includes multiple mech or vehicle minis and associated pilot cards, such as the Inner Sphere Tecon Lance with Firestarter, Ostscout, Spector, and Javelin mechs, or the Clan Cavalry Star set with the Black Python, Shadow Hawk, Griffin, Jenner, and Locust mechs. Those sets are available now, while the Inner Sphere Security Lance box with Marauder, Archer, Atlas, and Grasshopper mechs is available to preorder for $30 ahead of its February 5 release date. Check out all the new and upcoming BattleTech miniatures in the list below.New BattleTech mech and vehicle miniaturesBattleTech: Battlefield Support - Assault & Cavalry Lances vehicle miniatures set -- $40BattleTech: Battlefield Support - Recon & Hunter Lances vehicle miniatures set -- $40BattleTech: Battlefield Support - Rifle & Command Lances vehicle miniatures set -- $40BattleTech: Clan Cavalry Star mech miniatures set -- $35BattleTech: Inner Sphere Recon Lance mech minatures set -- $30BattleTech: Inner Sphere Security Lance mech miniatures set -- $30 | Preorder, releases February 5 BattleTech 40th Anniversary Edition $58.19 See at Amazon Continue Reading at GameSpot

Lugia recently received a unique makeover, with a Pokemon fan merging its appearance with Luigi from the Super Mario franchise. While this character combination might not immediately come to mind for many, the Pokemon fan artist revealed the Luigi-themed makeover fit the creature surprisingly well.

One of Stardew Valley's core mechanics is building relationships with NPCs. From romantic connections to neighborly bonds, the player can grow close to almost everyone in town and go from being an outsider to a real member of the community. The easiest way to win villagers' hearts is through generosity. Giving gifts, running errands posted on the bulletin board, and simply talking to people will raise their affection.