Scientists Investigate 2.2-Million-Year-Old Tooth Enamel to Unravel the Mysteries of Ancient Human Relatives
Scientists Investigate 2.2-Million-Year-Old Tooth Enamel to Unravel the Mysteries of Ancient Human Relatives
By studying proteins preserved in teeth, researchers determined the sex of four Paranthropus robustus individuals that lived in southern Africa
This skull of a 1.8-million-year-old Paranthropus robustus individual was unearthed in South Africa, but it was not one of the fossils included in the study.
José Braga and Didier Descouens via Wikimedia Commons under CC BY-SA 4.0
Paranthropus robustus was a prehistoric, two-legged human relative that lived in southern Africa roughly two million years ago. Scientists have unearthed various P. robustus fossils, but because of the specimens’ age, they haven’t been able to glean much from them.
Now, using a novel method, researchers say they’ve determined the sex of four P. robustus individuals by studying their teeth. The new analysis, published Thursday in the journal Science, also reveals insights into the genetic diversity of the broader Paranthropus genus.
For the study, the team analyzed teeth discovered in a cave at the Swartkrans paleoanthropological site in South Africa, reports Live Science’s Kristina Killgrove. Because the fossils were so old—dating to between 1.8 million and 2.2 million years ago—researchers could not recover ancient DNA from them. So, instead, they turned to the relatively new field of paleoproteomics, or the study of preserved proteins.
Ancient DNA degrades over time, particularly in hot places like southern Africa. So far, scientists studying hominin remains on the continent have only been able to successfully sequence DNA from material that’s less than 20,000 years old. But proteins can survive much longer than DNA, particularly in hard tooth enamel.
When they analyzed the fossilized enamel of the P. robustus teeth, the researchers were able to identify specific protein sequences found only in males. This allowed them to determine that two of the P. robustus individuals were male and two were female.
They were surprised to learn that one individual, named SK 835, was male. Based on the comparatively small size of that individual’s teeth, researchers had previously thought SK 835 was female, since male hominins tend to be larger than females, on average.
This marks an important finding, as it supports the idea that dental measurements are not the most reliable way to determine the sex of ancient hominins.
“Paleoanthropologists have long known that our use of tooth size to estimate sex was fraught with uncertainty, but it was the best we had,” says Paul Constantino, a paleoanthropologist at Saint Michael’s College who was not involved with the research, to ScienceNews’ Bruce Bower. “Being able to accurately identify the sex of fossils using proteins will be hugely impactful.”
Further analyses of the fossils’ amino acid sequences revealed that SK 835 was less closely related to the other three individuals than they were to each other. That means it’s possible SK 835 represents a different species altogether—maybe the newly proposed Paranthropus capensis. After all, the team writes in the paper, the recent description of that species shows Paranthropus diversity “is currently underestimated and needs to be investigated further.”
Or, perhaps the small size of SK 835’s teeth can be explained by microevolution—variations between P. robustus groups living at different sites. Scientists say they will need to get their hands on more Paranthropus fossils from multiple places to know for certain, per Science News.
Moving forward, researchers hope they can one day use paleoproteomic methods to map the entire human family tree. Right now, however, their “ability to distinguish between different species is limited by the small number of different proteins present in enamel,” three of the study authors tell Live Science in an email.
Scientists are also exploring other protein-sequencing techniques that are less destructive to fossil samples than the current methods. In the meantime, they’re excited about the potential of paleoproteomics to help them learn even more about humans’ ancient ancestors.
“It opens entirely new avenues for understanding our evolutionary history,” study co-author Marc Dickinson, a chemist at the University of York in England, says in a statement.
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#scientists #investigate #22millionyearold #tooth #enamel
Scientists Investigate 2.2-Million-Year-Old Tooth Enamel to Unravel the Mysteries of Ancient Human Relatives
Scientists Investigate 2.2-Million-Year-Old Tooth Enamel to Unravel the Mysteries of Ancient Human Relatives
By studying proteins preserved in teeth, researchers determined the sex of four Paranthropus robustus individuals that lived in southern Africa
This skull of a 1.8-million-year-old Paranthropus robustus individual was unearthed in South Africa, but it was not one of the fossils included in the study.
José Braga and Didier Descouens via Wikimedia Commons under CC BY-SA 4.0
Paranthropus robustus was a prehistoric, two-legged human relative that lived in southern Africa roughly two million years ago. Scientists have unearthed various P. robustus fossils, but because of the specimens’ age, they haven’t been able to glean much from them.
Now, using a novel method, researchers say they’ve determined the sex of four P. robustus individuals by studying their teeth. The new analysis, published Thursday in the journal Science, also reveals insights into the genetic diversity of the broader Paranthropus genus.
For the study, the team analyzed teeth discovered in a cave at the Swartkrans paleoanthropological site in South Africa, reports Live Science’s Kristina Killgrove. Because the fossils were so old—dating to between 1.8 million and 2.2 million years ago—researchers could not recover ancient DNA from them. So, instead, they turned to the relatively new field of paleoproteomics, or the study of preserved proteins.
Ancient DNA degrades over time, particularly in hot places like southern Africa. So far, scientists studying hominin remains on the continent have only been able to successfully sequence DNA from material that’s less than 20,000 years old. But proteins can survive much longer than DNA, particularly in hard tooth enamel.
When they analyzed the fossilized enamel of the P. robustus teeth, the researchers were able to identify specific protein sequences found only in males. This allowed them to determine that two of the P. robustus individuals were male and two were female.
They were surprised to learn that one individual, named SK 835, was male. Based on the comparatively small size of that individual’s teeth, researchers had previously thought SK 835 was female, since male hominins tend to be larger than females, on average.
This marks an important finding, as it supports the idea that dental measurements are not the most reliable way to determine the sex of ancient hominins.
“Paleoanthropologists have long known that our use of tooth size to estimate sex was fraught with uncertainty, but it was the best we had,” says Paul Constantino, a paleoanthropologist at Saint Michael’s College who was not involved with the research, to ScienceNews’ Bruce Bower. “Being able to accurately identify the sex of fossils using proteins will be hugely impactful.”
Further analyses of the fossils’ amino acid sequences revealed that SK 835 was less closely related to the other three individuals than they were to each other. That means it’s possible SK 835 represents a different species altogether—maybe the newly proposed Paranthropus capensis. After all, the team writes in the paper, the recent description of that species shows Paranthropus diversity “is currently underestimated and needs to be investigated further.”
Or, perhaps the small size of SK 835’s teeth can be explained by microevolution—variations between P. robustus groups living at different sites. Scientists say they will need to get their hands on more Paranthropus fossils from multiple places to know for certain, per Science News.
Moving forward, researchers hope they can one day use paleoproteomic methods to map the entire human family tree. Right now, however, their “ability to distinguish between different species is limited by the small number of different proteins present in enamel,” three of the study authors tell Live Science in an email.
Scientists are also exploring other protein-sequencing techniques that are less destructive to fossil samples than the current methods. In the meantime, they’re excited about the potential of paleoproteomics to help them learn even more about humans’ ancient ancestors.
“It opens entirely new avenues for understanding our evolutionary history,” study co-author Marc Dickinson, a chemist at the University of York in England, says in a statement.
Get the latest stories in your inbox every weekday.
#scientists #investigate #22millionyearold #tooth #enamel
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