In Stardew Valley, the Dangerous Mines are activated by accepting the "Danger In The Deep" quest from Mr. Qi, or by using the Shrine of Challenge, located on the 120th floor of the Mines. They are known to be one of the most challenging aspects of the game, featuring a new selection of monsters that are even tougher than those found in the Skull Cavern. This makes the Dangerous Mines a significant challenge, even for the most experienced players.