UnitedHealthcare CEO Brian Thompson was fatally shot in New York City on Wednesday, the police said.The NYPD said Thompson, 50, appeared to be killed in a targeted attack.Police officials say they have reason to believe the suspect has left New York City.Police believe the suspect in the fatal shooting of UnitedHealthcare CEO Brian Thompson in Midtown Manhattan left New York City shortly after fleeing the scene Wednesday, as investigators broaden the scope of their dayslong manhunt.Police told CNN they believe the suspect left the city via the Port Authority's George Washington Bridge Bus Station on the northern edge of Manhattan."We have video of him entering the Port Authority bus terminal. We don't have any video of him exiting so we believe he may have gotten on a bus," NYPD Chief of Detectives Joseph Kenny said in an interview published Friday. "Those buses are interstate buses. That's why we believe he may have left New York City," Kenny said.New York Police Department Commissioner Jessica Tisch told CNN the man wanted for the killing has been "traveling and walking around the streets of New York City largely in a mask, with his face covered. We had to go through lots of video evidence to get that one money shot with the mask down."The NYPD on Thursday released what Tisch called the "money shot" surveillance images giving the clearest picture yet of the suspected shooter in the early Wednesday killing of Thompson. Tisch told CNN police released those photos of the suspect not wearing a mask because they wanted a "wider audience to see the picture outside of New York City.""We are right now processing a tremendous amount of evidence in this case," the NYPD commissioner told the news outlet.Tisch said authorities already have "lots of forensic evidence," including fingerprints and DNA evidence.There's also a "massive camera canvass" of the suspected gunman's movements through New York City, Tisch told CNN.A law enforcement official told the outlet on Friday that investigators had also found a backpack in Central Park that they believed belonged to the suspect.The official said investigators had not officially confirmed where the bag had come from and that it was being taken for tests.As investigators work to identify the suspect, an NYPD spokesperson told Business Insider in an email on Saturday that the suspect "could possibly be a disgruntled employee or a disgruntled client."The spokesperson did not say what evidence the department has that leads investigators to believe so.Thompson was fatally shot outside Manhattan's New York Hilton Midtown hotel early Wednesday morning in what the police have described as "a brazen, targeted attack."Friday marks the third day of an intense manhunt for the shooting suspect, whose image was captured on surveillance cameras in the hours before Thompson was shot multiple times on the sidewalk outside the hotel in the heart of Manhattan.Thompson was set to speak at UnitedHealth Group's 8 a.m. investor conference when a hooded gunman opened fire from behind, striking him at least once in the back and at least once in the right calf, the police said."Every indication is that this was a premeditated, pre-planned, targeted attack," Tisch told reporters Wednesday at a press conference hours after the shooting, which the police said took place at 6:46 a.m. outside 1335 6th Avenue."It appears the suspect was lying in wait for several minutes," Tisch added.The police said the gunman fled the scene first on foot and then on an electric bike, which he rode into Central Park.The NYPD is offering a $10,000 reward for tips leading to the gunman's arrest. The FBI said it is also offering a reward of up to $50,000 for information leading to the gunman's arrest and conviction.Kenny, the NYPD chief of detectives, told CNN on Friday that investigators do not yet know the suspect's identity.Investigators are still pursuing additional leads. According to multiple reports, they were conducting forensic tests on a discarded cell phone, protein bar wrapper, and water bottle.How the suspect arrived in New York is becoming clearer. According to multiple reports, authorities believe he may have traveled to the city ten days before the shooting, on November 24, on a bus that originated in Atlanta and dropped him off at Manhattan's main bus depot, the Port Authority Bus Terminal. It was not yet clear where along the route he boarded the bus.The Atlanta Police Department announced Friday that it was contacted by NYPD and will be providing assistance in the investigation as needed. NYPD released images of the suspect in Brian Thompson's killing. DCPI/NYPD The unmasked images of the wanted man were captured at a hostel on New York City's Upper West Side, a law enforcement official told CNN, when an employee asked the man to lower his face mask."That little flirtation between the two of them, in some good-humored way, actually yielded what is so far the most significant clue to identifying him," CNN's chief law enforcement and intelligence analyst, John Miller, said.The new photos will speed the chase considerably, Salvatore Tudisco, a retired NYPD homicide detective, told BI.Tudisco led the city's last big manhunt for a murdered CEO, Gokada founder Fahim Saleh, whose killer was captured in three days by traces on credit card, cell phone, and surveillance camera evidence."That's the best option to send it across the country, and someone will know him," the ex-detective said of the latest images.A facial-recognition trace will be less of an option, he added, because the hostel surveillance images do not show the suspect's full face."The ears are missing. The eyes, too," he said. "Facial recognition works better when the perp is facing forward."Investigators can still try to run the photo through state driver's license and arrest databases, he said, though some states require a judge to issue a warrant before state driver's licenses can be used as evidence in an arrest and beyond.On Friday, The New York Times reported that the suspect used a fake New Jersey ID to book a room at the hostel, citing an unnamed senior law enforcement official.Shooter was 'proficient in the use of firearms,' police saidUnitedHealth Group, the parent company of UnitedHealthcare, said in a statement, "We are deeply saddened and shocked at the passing of our dear friend and colleague Brian Thompson, the CEO of UnitedHealthcare.""Brian was a highly respected colleague and friend to all who worked with him," the statement said. "We are working closely with the New York Police Department and ask for your patience and understanding during this difficult time. Our hearts go out to Brian's family and all who were close to him."Kenny said at the NYPD's press conference in the aftermath of the shooting that the gunman arrived on 6th Avenue about five minutes before Thompson."The shooter steps onto the sidewalk from behind the car. He ignores numerous other pedestrians, approaches the victim from behind, and shoots him in the back," Kenny said. "The shooter then walks toward the victim and continues to shoot."Kenny added that the shooter's weapon appeared to jam during the attack."From watching the video, it does seem that he's proficient in the use of firearms, as he was able to clear the malfunctions pretty quickly," Kenny said.Surveillance footage captured the incident, showing the gunman firing his weapon as Thompson, wearing a blue suit jacket, was walking several feet in front of him.A law-enforcement source, who is not authorized to talk to the press, told Business Insider that the gun appeared to be equipped with a silencer. The source added that the gunman "definitely knew" where Thompson was going to be. UnitedHealth Group canceled its investor day shortly after reports of the shooting broke. Paul Squire/ BI The police said officers found Thompson unconscious and unresponsive two minutes after the shooting. Emergency responders rushed him to Mount Sinai Hospital, where he was pronounced dead at 7:12 a.m.Police have not identified a motiveThe shooting occurred blocks from Midtown holiday tourism landmarks, including Radio City Music Hall and Rockefeller Center, whose Christmas tree lighting took place Wednesday night.By late Wednesday morning, six evidence cups remained on the taped-off section of the sidewalk where the shooting happened."That's covering the shell casings," an officer at the scene told BI, declining to give their name because they were not authorized to talk to the media.UnitedHealth Group canceled its "investor day" conference shortly after reports of the shooting broke.Investigators have not yet determined a motive for the killing.Kenny said investigators were combing through Thompson's social media and interviewing employees and family members and would be talking to law enforcement in Minnesota, where Thompson lived and where UnitedHealth Group and UnitedHealthcare are based.Thompson's wife, Paulette Thompson, told NBC News in an interview that her husband had been receiving threats."Basically, I don't know, a lack of coverage?" she said. "I don't know details. I just know that he said there were some people that had been threatening him."The police department in his hometown of Maple Grove, Minnesota, told BI it hadn't been notified of any threats he might have received. Theresa Keehn, the Maple Grove police administrator, initially said Maple Grove had no record of calls for service to his house, but the department later said it had responded to a 2018 call from Paulette Thompson. An incident report said she had been walking to bed when she saw the front door deadbolt turn and grew afraid someone was inside the house. The police did not find anyone inside the house.An unnamed senior law enforcement official told NBC News that shell cases found at the scene were inscribed with the words "deny," "defend," and "depose." BI has not independently confirmed the description of the evidence, and an NYPD spokesperson didn't return a request for comment.Jay M. Feinman, an author and legal professor who specializes in insurance law, torts, and contract law, wrote a similarly titled book "Delay Deny Defend: Why Insurance Companies Don't Pay Claims and What You Can Do About It."The book is dubbed an expos of insurance injustice and explains how people can be more careful when shopping for insurance policies and what to do when pursuing a disputed claim.The NYPD said Thompson arrived in New York City on Monday and was staying at a hotel across the street from where he was shot.Police in Maple Grove, Minnesota, told BI homes of Thompson and his wife in a suburb outside Minneapolis were targeted with fake bomb threats Wednesday evening, more than 13 hours after the shooting. The police marked evidence at the scene of the shooting. Laura Italiano/BI Thompson was remembered as a 'hardworking Midwest guy.'Thompson spent 20 years at UnitedHealth Group and served as CEO of UnitedHealthcare, the health-benefits unit, since April 2021.While announcing his promotion, the company said Thompson would "drive continued growth across the global, employer, individual, specialty, and government benefits business while continuing the company's focus on ensuring access to high-quality, affordable healthcare."Leaders in the healthcare industry shared their condolences in the hours after Thompson's death.UnitedHealth's shares were broadly unchanged after the shooting. They've gained about 12% in the past 12 months, less than the 32% increase in the S&P 500 but outperforming competitors including CVS Health, Humana, and Elevance Health. During its third-quarter results in October, it gave what UBS called a "more conservative than usual" outlook for fiscal 2025. Ahead of Wednesday's investor day, it gave more detailed guidance for next year, forecasting revenue of $450 billion to $455 billion and adjusted earnings of $29.50 to $30 a share. The company also suffered a ransomware attack that disrupted pharmacy deliveries earlier this year.By Wednesday afternoon, UnitedHealth Group had removed the names of its executives from its website, an archived version of its site shows. Some executives also appeared to have deleted their LinkedIn profiles, though it's not clear when.Thompson had previously served as CEO of the group's government programs, running its programs for Medicare and Medicaid recipients.Minnesota's governor, Tim Walz, the 2024 Democratic vice-presidential nominee, said in a statement on the social-media site X that the shooting death was "horrifying news and a terrible loss for the business and health care community in Minnesota.""Minnesota is sending our prayers to Brian's family and the UnitedHealthcare team," Walz said.Thompson's former brother-in-law, Bassel El-Kasaby, told Business Insider that Thompson was "a good guy, very successful and very humble just a decent, hardworking Midwest guy.""Whoever did this is a coward and a loser," El-Kasaby said.Correction: December 4, 2024 An earlier version of this story misstated Thompson's work history at United Health. He worked at the company for 20 years but was not an executive there for 20 years.Update December 7, 2024: This story was updated as the manhunt continued.