Image of the Archbishop of Canterbury's letters to the Bishop of Winchester on the subject of Ela Fitzpayne, from the register of John de Stratford. Reproduced with permission of Hampshire Archives and Hampshire County Council. (Image Credit: Register of John de Stratford. Reproduced with permission of Hampshire Archives and Hampshire County Council.)NewsletterSign up for our email newsletter for the latest science newsEspionage, sex, public humiliation, murder — these may sound like tropes straight out of Game of Thrones, but they’re actually all elements of a nearly 700-year-old cold case in England. After analyzing Medieval letters and records, a research team from the Cambridge University Institute of Criminology’s Medieval Murder Maps project may have found the killer of a priest. However, this priest may not have been so innocent. A new paper published in Criminal Law Forum takes a deeper look at this 14th-century cold case.Tracing a Medieval MurderThe Medieval Murder Maps project uses interactive maps of three English cities, London, Oxford, and York, during the Medieval period. Throughout the cities are the locations of various deaths and murders. Each location has a story associated with it, directly from written records and coroners' reports at the time. Some of these stories are full of intriguing twists and turns.The Cambridge research team analyzed over 100 murders from texts, translated from Latin, from that period, and used a coding method to separate the deaths into different categories, including time (day, week, month), motivation, weapon used, victim, and location. From this information, one of the deaths the team found most interesting was the murder of John Forde in 1337.A Medieval Lover to Murderer From the letters and texts the team analyzed, they pieced together the events that led up to Forde’s death. Forde was a priest living in London when he was murdered on a busy street. But what possible reason would someone have to want to murder a priest? The motive, according to the research team, was likely revenge. According to Manuel Eisner, one of the study’s authors, the murder may have been an act of revenge by noblewoman Ela Fitzpayne. According to the records, the Archbishop of Canterbury, Simon Mepham, had enacted penance on Fitzpayne after it was discovered that Forde had been her lover. A letter written by Archbishop Mepham accused Fitzpayne of adultery with Forde and possibly others. Her penance was to take a barefoot walk of shame across Salisbury Cathedral. Eisner also found a document that suggested Fitzpayne, her husband, and John Forde sent a gang to rob a church priory and took the livestock for ransom. It’s possible that during this time, Forde found himself in bed with Fitzpayne, before betraying her to the Archbishop Mepham. Commissioned Murder Possibly betrayed by her former lover and sentenced to walks of shame that were to take place once a year for seven years,  Fitzpayne would have none of it. On an early evening on a busy London street, near St. Paul’s Cathedral, three men attacked Forde. One slit his throat while the others stabbed him in the gut. Witnesses claim that the murderers were Fitzpayne’s brother and two of her former servants. “We are looking at a murder commissioned by a leading figure of the English aristocracy. It is planned and cold-blooded, with a family member and close associates carrying it out, all of which suggests a revenge motive,” said Eisner in a press release.Cold Case RevealedAccording to letters from Archbishop Mepham, Fitzpayne was led by the devil and a “spirit of pride.”“The archbishop imposed heavy, shameful public penance on Ela, which she seems not to have complied with, but may have sparked a thirst for vengeance,” said Eisner in a press release. “Not least as John Forde appears to have escaped punishment by the church.” When Archbishop Mepham died in 1333, Fitzpayne waited four years before enacting her revenge, and in 1337, Forde was killed. Article SourcesOur writers at Discovermagazine.com use peer-reviewed studies and high-quality sources for our articles, and our editors review for scientific accuracy and editorial standards. Review the sources used below for this article:A graduate of UW-Whitewater, Monica Cull wrote for several organizations, including one that focused on bees and the natural world, before coming to Discover Magazine. Her current work also appears on her travel blog and Common State Magazine. Her love of science came from watching PBS shows as a kid with her mom and spending too much time binging Doctor Who.1 free article leftWant More? Get unlimited access for as low as $1.99/monthSubscribeAlready a subscriber?Register or Log In1 free articleSubscribeWant more?Keep reading for as low as $1.99!SubscribeAlready a subscriber?Register or Log In

Bacteria wouldn’t be so bad if we could tell them what to do. “Stop spreading! Stop sticking together! Stop fending off our antibiotics!” A new method is starting to allow scientists to do just that, letting them use light to control certain functions of bacteria. Introduced in a paper published in The European Physical Journal Plus, the preliminary approach could have several potential applications, including a possible avenue for combating antibiotic resistance.The Problem of Antibacterial Resistance Bacteria are behind a variety of diseases, from strep to staph to pneumonia and meningitis, and they attack our bodies in a variety of ways, as well, including through the production of toxins that damage and disrupt our cells. Some of these infections stop on their own, but others are too stubborn, or too serious, to leave untreated. These are the infections that we target with antibiotics — that is, as long as our antibiotics are working.But, because bacteria are constantly changing, they can develop defenses against the antibiotics that we use to stave them off, making these treatments much less effective. That’s the gist of the growing threat posed by antibiotic resistance, which has contributed to millions of deaths since 1990 and is anticipated to contribute to millions more by 2050. Setting out to find a new solution to this growing problem, scientists from the Italian Institute of Technology and the Polytechnic University of Milan embarked on the Engineering of Bacteria to See Light (EOS) project. The project aims to use light to control bacteria, primarily for the fight against antibiotic resistance. And the new method pushes the project closer to achieving that aim. Using light and light-sensitive molecules to adjust the electrical signals that are transmitted across the bacterial membrane, the method impacts the biological activity of bacteria without any alterations to their genetic makeup.“This interplay between light and electrical [signaling] allows us to control key biological processes such as movement, biofilm formation, and antibiotic sensitivity,” said Giuseppe Maria Paternò, a study author and a professor at the Polytechnic University of Milan, according to a press release. “We can influence antibiotic uptake and restore or even enhance the effectiveness of treatments against resistant strains.”Coating Bacteria to Curb Antibiotic ResistanceTo control bacteria, the method takes advantage of a light-sensitive molecule called Ziapin2, which sticks to the bacterial surface. By covering bacteria with this light-sensitive molecule and by subjecting the covered bacteria to light, the scientists were able to modify the electrical signals that were transmitted across their bacterial membranes, transforming the bacteria’s basic functioning. Testing their method on one of the most studied bacterial species, the scientists changed the electrical signaling across the membranes of Bacillus subtilis, a popular model organism that’s often used as a stand-in for Staphylococcus aureus, the bacterium that causes staphylococcus, or staph, infections.When tested, the method modulated the bacteria’s susceptibility to Kanamycin, an intracellular antibiotic that’s frequently used as a treatment for severe bacterial infections after other treatments fail. “Under blue light,” Paternò said in the release, “the effectiveness of Kanamycin was significantly reduced,” indicating that the electrical signaling on the bacterial membrane “plays a crucial role in the drug’s uptake.”Additional research is required to tailor the method to increase the effectiveness of Kanamycin and other antibiotics against bacteria. But for now, it seems that such an outcome could be possible. “This initial assessment […] represents a first step in a completely new field of study,” the scientists state in their paper. “This proof-of-concept study underscores the potential of non-genetic, light-based interventions to modulate bacterial susceptibility in real time. Future work will expand this approach […] ultimately advancing our understanding of bacterial bioelectric regulation and its applications in antimicrobial therapies.”This article is not offering medical advice and should be used for informational purposes only.Article SourcesOur writers at Discovermagazine.com use peer-reviewed studies and high-quality sources for our articles, and our editors review for scientific accuracy and editorial standards. Review the sources used below for this article:The European Physical Journal Plus. Photocontrol of Bacterial Membrane Potential Regulates Antibiotic Persistence in B. SubtilisSam Walters is a journalist covering archaeology, paleontology, ecology, and evolution for Discover, along with an assortment of other topics. Before joining the Discover team as an assistant editor in 2022, Sam studied journalism at Northwestern University in Evanston, Illinois.

June 3, 20255 min readAre We Ready for Death in Space?NASA has quietly taken steps to prepare for a death in space. We need to ask how nations will deal with this inevitability now, as more people start traveling off the planetBy Peter Cummings edited by Lee Billings SciePro/Science Photo Library/Getty ImagesIn 2012 NASA stealthily slipped a morgue into orbit.No press release. No fanfare. Just a sealed, soft-sided pouch tucked in a cargo shipment to the International Space Station (ISS) alongside freeze-dried meals and scientific gear. Officially, it was called the Human Remains Containment Unit (HRCU). To the untrained eye it looked like a shipping bag for frozen cargo. But to NASA it marked something far more sobering: a major advance in preparing for death beyond Earth.As a kid, I obsessed over how astronauts went to the bathroom in zero gravity. Now, decades later, as a forensic pathologist and a perennial applicant to NASA’s astronaut corps, I find myself fixated on a darker, more haunting question:On supporting science journalismIf you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.What would happen if an astronaut died out there? Would they be brought home, or would they be left behind? If they expired on some other world, would that be their final resting place? If they passed away on a spacecraft or space station, would their remains be cast off into orbit—or sent on an escape-velocity voyage to the interstellar void?NASA, it turns out, has begun working out most of these answers. And none too soon. Because the question itself is no longer if someone will die in space—but when.A Graying CorpsNo astronaut has ever died of natural causes off-world. In 1971 the three-man crew of the Soviet Soyuz 11 mission asphyxiated in space when their spacecraft depressurized shortly before its automated atmospheric reentry—but their deaths were only discovered once the spacecraft landed on Earth. Similarly, every U.S. spaceflight fatality to date has occurred within Earth’s atmosphere—under gravity, oxygen and a clear national jurisdiction. That matters, because it means every spaceflight mortality has played out in familiar territory.But planned missions are getting longer, with destinations beyond low-Earth orbit. And NASA’s astronaut corps is getting older. The average age now hovers around 50—an age bracket where natural death becomes statistically relevant, even for clean-living fitness buffs. Death in space is no longer a thought experiment. It’s a probability curve—and NASA knows it.In response, the agency is making subtle but decisive moves. The most recent astronaut selection cycle was extended—not only to boost intake but also to attract younger crew members capable of handling future long-duration missions.NASA’s Space MorgueIf someone were to die aboard the ISS today, their body would be placed in the HRCU, which would then be sealed and secured in a nonpressurized area to await eventual return to Earth.The HRCU itself is a modified version of a military-grade body bag designed to store human remains in hazardous environments. It integrates with refrigeration systems already aboard the ISS to slow decomposition and includes odor-control filters and moisture-absorbent linings, as well as reversed zippers for respectful access at the head. There are straps to secure the body in a seat for return, and patches for name tags and national flags.Cadaver tests conducted in 2019 at Sam Houston State University have proved the system durable. Some versions held for over 40 days before decomposition breached the barrier. NASA even drop-tested the bag from 19 feet to simulate a hard landing.But it’s never been used in space. And since no one yet knows how a body decomposes in true microgravity (or, for that matter, on the moon), no one can really say whether the HRCU would preserve tissue well enough for a forensic autopsy.This is a troubling knowledge gap, because in space, a death isn’t just a tragic loss—it’s also a vital data point. Was an astronaut’s demise from a fluke of their physiology, or an unavoidable stroke of cosmic bad luck—or was it instead a consequence of flaws in a space habitat’s myriad systems that might be found and fixed? Future lives may depend on understanding what went wrong, via a proper postmortem investigation.But there’s no medical examiner in orbit. So NASA trains its crews in something called the In-Mission Forensic Sample Collection protocol. The space agency’s astronauts may avoid talking about it, but they all have it memorized: Document everything, ideally with real-time guidance from NASA flight surgeons. Photograph the body. Collect blood and vitreous fluid, as well as hair and tissue samples. Only then can the remains be stowed in the HRCU.NASA has also prepared for death outside the station—on spacewalks, the moon or deep space missions. If a crew member perishes in vacuum but their remains are retrieved, the body is wrapped in a specially designed space shroud.The goal isn’t just a technical matter of preventing contamination. It’s psychological, too, as a way of preserving dignity. Of all the “firsts” any space agency hopes to achieve, the first-ever human corpse drifting into frame on a satellite feed is not among them.If a burial must occur—in lunar regolith or by jettisoning into solar orbit—the body will be dutifully tracked and cataloged, treated forevermore as a hallowed artifact of space history.Such gestures are also of relevance to NASA’s plans for off-world mourning; grief and memorial protocols are now part of official crew training. If a death occurs, surviving astronauts are tasked with holding a simple ceremony to honor the fallen—then to move on with their mission.Uncharted RealmsSo far we’ve only covered the “easy” questions. NASA and others are still grappling with harder ones.Consider the issue of authority over a death and mortal remains. On the ISS, it’s simple: the deceased astronaut’s home country retains jurisdiction. But that clarity fades as destinations grow more distant and the voyages more diverse: What really happens on space-agency missions to the moon, or to Mars? How might rules change for commercial or multinational spaceflights—or, for that matter, the private space stations and interplanetary settlements that are envisioned by Elon Musk, Jeff Bezos and other tech multibillionaires?NASA and its partners have started drafting frameworks, like the Artemis Accords—agreements signed by more than 50 nations to govern behavior in space. But even those don’t address many intimate details of death.What happens, for instance, if foul play is suspected?The Outer Space Treaty, a legal document drafted in 1967 under the United Nations that is humanity’s foundational set of rules for orbit and beyond, doesn’t say.Of course, not everything can be planned for in advance. And NASA has done an extraordinary job of keeping astronauts in orbit alive. But as more people venture into space, and as the frontier stretches to longer voyages and farther destinations, it becomes a statistical certainty that sooner or later someone won’t come home.When that happens, it won’t just be a tragedy. It will be a test. A test of our systems, our ethics and our ability to adapt to a new dimension of mortality. To some, NASA’s preparations for astronautical death may seem merely morbid, even silly—but that couldn’t be further from the truth.Space won’t care of course, whenever it claims more lives. But we will. And rising to that grim occasion with reverence, rigor and grace will define not just policy out in the great beyond—but what it means to be human there, too.

It’s time to game. Kicking off June 6, with Summer Game Fest Live, SGF 2025 runs through to June 9, with the likes of Xbox Games Showcase and even Death Stranding 2 live game premiere likely to make headlines. There is a bunch of others in store, inc

Nearly two decades ago, scientists made an alarming discovery in upstate New York: Bats, the world’s only flying mammal, were becoming infected with a new, deadly fungal disease that, in some cases, could wipe out an entire colony in a matter of months. Since then, the disease — later called white-nose syndrome — has spread across much of the country, utterly decimating North American bats that hibernate in caves and killing over 90 percent of three bat species. According to some scientists, WNS has caused “the most precipitous wildlife decline in the past century in North America.” These declines have clear consequences for human populations — for you, even if you don’t like bats or visit caves. Bats eat insect pests, such as moths and beetles. And as they decline, farmers need to spray more pesticides. Scientists have linked the loss of bats in the US to an increase in insecticide use on farmland and, remarkably, to a rise in infant deaths. Insecticide chemicals are known to harm the health of newborns. The only reason we know any of this is because of a somewhat obscure government program in the US Geological Survey (USGS), an agency nested within the Interior Department. That program, known as the Ecosystems Mission Area (EMA), is the biological research division of Interior. Among other functions, it monitors environmental contaminants, the spread of invasive species, and the health of the nation’s wildlife, including bees, birds, and bats.White-nose syndrome, a fungal disease, has caused massive declines in a handful of bat species, including the tricolored bat, shown here in flight. J. Scott Altenbach/Bat Conservation InternationalThe Ecosystems Mission Area, which has around 1,200 employees, produces the premier science revealing how animals and ecosystems that Americans rely on are changing and what we can do to keep them intact — or risk our own health and economy. This program is now at an imminent risk of disappearing.Send us a confidential tipAre you a current or former federal employee with knowledge about the Trump administration’s attacks on wildlife protections? Reach out to Vox environmental correspondent Benji Jones on Signal at benji.90 or at benji.jones@vox.com or at benjijones@protonmail.com.In the White House’s 2026 budget request, the Trump administration asked Congress to slash funding for EMA by about 90 percent, from $293 million in 2025 to $29 million next year. Such cuts are also in line with Project 2025, the Heritage Foundation’s conservative policy roadmap, which calls for the government to “abolish” Interior’s Biological Resources Division, an outdated name for the Ecosystems Mission Area.Meanwhile, the Trump administration is also reportedly trying to fire government employees in the Ecosystems Mission Area, though a federal judge has so far blocked those efforts. Eliminating biological research is not good. In fact, it’s very bad.For a decade now, EMA’s North American Bat Monitoring Program, or NABat, has been gathering and analyzing data on bats and the threats they face. NABat produces research using data from hundreds of partner organizations showing not only how white-nose syndrome is spreading — which scientists are using to develop and deploy vaccines — but also how bats are affected by wind turbines, another known threat. Energy companies can and do use this research to develop safer technologies and avoid delays caused by wildlife regulations, such as the Endangered Species Act. The irony, an Interior Department employee told me, is that NABat makes wildlife management more efficient. It also helps reveal where declines are occurring before they become severe, potentially helping avoid the need to grant certain species federal protection — something the Trump administration would seem to want. The employee, who’s familiar with Interior’s bat-monitoring efforts, spoke on the condition of anonymity for fear of retaliation by the Trump administration. A northern long-eared bat with white-nose syndrome. Steve Taylor/University of IllinoisA dead bat infected with white-nose syndrome under UV light. USGS“If they want to create efficiencies in the government, they should ask us,” another Interior employee told Vox. “The damage that can be done by one administration takes decades to rebuild.”In response to a request for comment, an Interior Department spokesperson told Vox that “USGS remains committed to its congressional mandate as the science arm of the Department of the Interior.” The White House did not respond to a request for comment. In a Senate appropriations hearing last week, Interior Secretary Doug Burgum refused to commit to maintaining funding for EMA.“There’s no question that they don’t know what EMA does,” said a third Interior employee, who has knowledge of the Ecosystems Mission Area.Ultimately, it’s not clear why the administration has targeted Interior’s biological research. EMA does, however, do climate science, such as studying how plants and animals are responding to rising temperatures. That’s apparently a no-go for the Trump administration. It also gathers information that sometimes indicates that certain species need federal protections, which come with regulations (also a no-go for President Donald Trump’s agenda).What’s especially frustrating for environmental advocates is that NABat, now 10 years old, is starting to hit its stride.“We should be celebrating the 10-year anniversary of this very successful program that started from scratch and built this robust, vibrant community of people all collecting data,” said Winifred Frick, the chief scientist at Bat Conservation International, an environmental group. “We have 10 years of momentum, and so to cut it off now sort of wastes all that investment. That feels like a tremendous loss.” Meanwhile, the cost of maintaining the program is less than 1 percent of Interior’s overall budget.The government’s wildlife monitoring programs are “jewels of the country,” said Hollis Woodard, an associate professor of entomology at University of California Riverside who works with USGS on bee monitoring. “These birds and bats perform services for us that are important for our day-to-day lives. Literally everything I value, including food, comes down to keeping an eye on these populations. The idea that we’re just going to wipe them out is just terrifying.”Update, June 2, 12:58 pm ET: This article was originally published on May 29, 2025, and has been updated to include newly public details on the 2026 White House budget request.See More:

Good News Colon cancer recurrence and deaths cut 28% by simple exercise, trial finds Any type of aerobic exercise works for the improvements, study finds. Beth Mole – Jun 2, 2025 6:05 pm | 42 Credit: Getty | Oli Kellett Credit: Getty | Oli Kellett Story text Size Small Standard Large Width * Standard Wide Links Standard Orange * Subscribers only   Learn more Exercise is generally good for you, but a new high-quality clinical trial finds that it's so good, it can even knock back colon cancer—and, in fact, rival some chemotherapy treatments. The finding comes from a phase 3, randomized clinical trial led by researchers in Canada, who studied nearly 900 people who had undergone surgery and chemotherapy for colon cancer. After those treatments, patients were evenly split into groups that either bulked up their regular exercise routines in a three-year program that included coaching and supervision or were simply given health education. The researchers found that the exercise group had a 28 percent lower risk of their colon cancer recurring, new cancers developing, or dying over eight years compared with the health education group. The benefits of exercise, published in the New England Journal of Medicine, became visible after just one year and increased over time, the researchers found. The rate of people who survived for five years and remained cancer-free was 80.3 percent among the exercise group. That's a 6.4 percentage-point survival boost over the education group, which had a 73.9 percent cancer-free survival rate. The overall survival rate (with or without cancer) during the study's eight-year follow-up was 90.3 percent in the exercise group compared with 83.2 percent in the education group—a 7.1 percentage point difference. Exercise reduced the relative risk of death by 37 percent (41 people died in the exercise group compared with 66 in the education group). "The magnitude of benefit from exercise ... was similar to that of many currently approved standard drug treatments," the researchers noted. However, the exercise routines that achieved those substantial benefits weren't heavy-duty. Participants were coached to perform any recreational aerobic exercise they enjoyed, including brisk walking. Adding 45- to 60-minute brisk walks three or four times a week, or three or four jogs lasting 25 to 30 minutes, was enough for many of the participants to improve their odds. Overall, the goal was to get the exercise group over 20 MET hours per week. METs are Metabolic Equivalents of Task, which represent the amount of energy your body is burning up compared to when you're at rest, sitting quietly. Brisk walking is about four METs, the researchers estimated, and jogging is around 10 METs. To get to 20 MET hours a week, a participant would have to do five hours of brisk walking a week (e.g., five hour-long walks a week) or jog for two hours a week (e.g., four 30-minute jogs per week). “Quite impressive” The exercise group, which had supervised exercise for the first six months of the three-year intervention, reported more exercise over the study. At the end, the exercise group was averaging over 20 MET hours per week, while the education group's average was around 15 MET hours per week. The exercise group also scored better at cardiorespiratory fitness and physical functioning. Still, with the health education, the control group also saw a boost to their exercise during the trial, with their average starting around 10 MET hours per week. These findings "raise the possibility of an even more powerful effect of exercise on cancer outcomes as compared with a completely sedentary control group," the researchers note. For now, it's not entirely clear how exercise keeps cancers at bay, but it squares with numerous other observational studies that have linked exercise to better outcomes in cancer patients. Researchers have several hypotheses, including that exercise might cause "increased fluid shear stress, enhanced immune surveillance, reduced inflammation, improved insulin sensitivity, and altered microenvironment of major sites of metastases," the authors note. In the study, exercise seemed to keep local and distant colon cancer from recurring, as well as prevent new cancers, including breast, prostate, and colorectal cancers. Outside experts hailed the study's findings. "This indicates that exercise has a similarly strong effect as previously shown for chemotherapy, which is really quite impressive," Marco Gerlinger, a gastrointestinal cancer expert at Queen Mary University of London, said in a statement. "One of the commonest questions from patients is what they can do to reduce the risk that their cancer comes back. Oncologists can now make a very clear evidence-based recommendation." "Having worked in bowel cancer research for 30 years, this is an exciting breakthrough in the step-wise improvement in cure rates," David Sebag-Montefiore, a clinical oncologist at the University of Leeds, said. "The great appeal of a structured moderate intensity exercise is that it offers the benefits without the downside of the well-known side effects of our other treatments." Beth Mole Senior Health Reporter Beth Mole Senior Health Reporter Beth is Ars Technica’s Senior Health Reporter. Beth has a Ph.D. in microbiology from the University of North Carolina at Chapel Hill and attended the Science Communication program at the University of California, Santa Cruz. She specializes in covering infectious diseases, public health, and microbes. 42 Comments

June 2, 20253 min readThe World Isn’t Ready for the Mental Health Toll of Extreme HeatTemperatures are rising, and so are mental health risksBy Madhusree Mukerjee edited by Dean VisserA man walks with an umbrella to protect himself from the heat as a yellow alert is issued by the UK Health Security Agency (UKHSA) due to increasing temperatures in London, United Kingdom on June 25, 2024. Rasid Necati Aslim/Anadolu via Getty ImagesThe coming summer is forecast to be a scorcher across the U.S. And climate scientists predict that at least one of the next five years will beat 2024 as the hottest year ever recorded globally. As heat waves are getting more intense and prolonged, their effect on the mind and body are also becoming more dire. Children and older people, as well as those who work outdoors, are most at risk. So are those with mental health disorders.Heat waves are the single highest cause of weather-related deaths in the U.S., where an estimated 1,300 fatalities from heat stroke and other temperature-related complications occur every year. Even those who survive a period of extreme heat may suffer serious neurological or other mental-health-related disorders.A new study published in Current Environmental Health Reports finds that the world is startlingly unprepared to deal with the mental health consequences of climate change. Of 83 action plans for heat-related health problems that were reviewed for the study, fewer than a third acknowledged the mental health effects of extreme or prolonged high temperatures. And only a fifth of these plans outlined specific actions to deal with contingencies such as increased hospitalizations for mental health disorders.On supporting science journalismIf you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today.How does extreme heat affect the brain?The human body operates optimally at 98.6 degrees Fahrenheit (37 degrees Celsius). If a person doesn’t drink enough water when the weather is hot and dry, the body becomes dehydrated, the blood thickens, and the heart may not be able to pump enough oxygen to the brain. Additionally, the human brain burns up 20 percent of the body’s energy and therefore needs to dissipate heat efficiently. In hot and humid conditions, sweating cannot cool the body and brain enough. This can lead to heat exhaustion, which has symptoms such as weakness, dizziness and headaches and, in extreme cases, heat stroke—which can then trigger delirium and loss of consciousness. A significant fraction of heat stroke survivors suffer neurological complications.Exposure to extreme heat can also increase the risk of suicide and can worsen schizophrenia, epilepsy, anxiety, depression, substance use disorder, neurodegenerative disorders (such as Alzheimer’s disease) and negative emotions such as fear and anger. It may worsen sleep, which, in turn, can increase fatigue and impair cognition. Alcohol and recreational drugs, as well as certain medications used to treat mental illness, such as antidepressants, tranquilizers and antipsychotics, also appear to increase mental health vulnerability to heat.Studies find an increased risk of suicide and epileptic seizures during heat waves, as well as an increase in hospitalizations and emergency-room visits for mental health disorders. Heat can also disorient thinking, making people slow to realize that they need to seek shelter or help.Who is most at risk?The most vulnerable are those with existing mental health disorders. Disturbingly, prolonged heat waves also appear to worsen the risk among young children—and even the unborn—of developing mental health ailments in the future. Older people may also be particularly affected, such as by accelerated dementia and Alzheimer’s.At particular risk are vast populations around the world who live without air-conditioning, including poor or homeless people and those who work outdoors, such as on farms.What can be done?The authors of the new Current Environmental Health Reports study point to interventions at several levels to help communities and individuals most at risk of climate mental health impacts. These can include public awareness campaigns, such as warning people about the mental health risk of consuming alcohol or other drugs during heat waves. Other interventions include establishing community cooling shelters for heat emergencies and increasing monitoring of mental health patients during heat waves. Extreme heat is here to stay, at least for the foreseeable future. We need to prepare people and communities to reduce the risk of mental health emergencies.IF YOU NEED HELPIf you or someone you know is struggling or having thoughts of suicide, help is available. Call or text the 988 Suicide & Crisis Lifeline at 988 or use the online Lifeline Chat.

June 3: Martyrs Day in Uganda Silhouette of Jack Jouett 1781 – American Revolutionary War: Jack Jouett (pictured) rode 40 miles (64 km) to warn Thomas Jefferson and the Virginia legislature of British cavalry who had been sent to capture them. 1892 – Liverpool F.C., one of England's most successful football clubs, was founded. 1937 – Half a year after abdicating the British throne, Edward, Duke of Windsor, married American socialite Wallis Simpson in a private ceremony in France. 1969 – During a SEATO exercise in the South China Sea, a collision between HMAS Melbourne and USS Frank E. Evans resulted in the latter vessel being cut in two and the deaths of 74 personnel. 1982 – A failed assassination attempt was made on Shlomo Argov, the Israeli ambassador to the United Kingdom, triggering an Israeli decision to invade Lebanon three days later. Garret Hobart (b. 1844)Eric A. Havelock (b. 1903)Franz Kafka (d. 1924)Pierre Poilievre (b. 1979) More anniversaries: June 2 June 3 June 4 Archive By email List of days of the year About

The narratives in Final Fantasy have been one of the aspects of the franchise that have evolved the most over time, always seeking new ways to forge deep connections with players through characters and all the context that surrounds the story. As a result, certain events often become landmark moments for players, whether when the plot reaches a crucial point or when the death of an important figure occurs, affecting the entire development of the cast from that point forward.

Any type of aerobic exercise works for the improvements, study finds.