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WWW.CREATIVEBLOQ.COMXTool F1 Ultra review: a high-end laser cutter and engraver for production useIt's a hefty investment that could still prove worthwhile for small creative businesses.0 Kommentare 0 Anteile 39 Ansichten
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WWW.MARKTECHPOST.COMTOMG-Bench: Text-based Open Molecule Generation BenchmarkMolecule discovery is important in various scientific research fields, particularly pharmaceuticals and materials science. While the emergence of Graph Neural Networks (GNNs) has revolutionized this field by enabling the representation of molecules as graphs and facilitating property predictions, it faces difficulties in generalizing across different tasks, requiring substantial task-specific data collection. These approaches show limitations in generating molecules with customized properties. The integration of LLMs into molecule discovery faces hurdles in effectively aligning molecular and textual data along with challenges in dataset availability and evaluation metrics that capture the aspects of new molecule discovery.Various artificial intelligence approaches have been developed to enhance molecule discovery. Integration of machine learning, deep learning, and natural language processing has enabled more complex analysis of biological and chemical data. Methods like Convolutional Neural Networks (CNNs) for structural analysis, Recurrent Neural Networks (RNNs) for sequential data processing, and Transformer-based networks for complex pattern recognition. Text-based Molecule Generation (Text2Mol) emerged as a beneficial approach, utilizing natural language descriptions for molecule retrieval. While models like MolT5 show initial success with SMILES string generation, subsequent developments like KVPLM, MoMu, and 3DMoLM enhanced capabilities using molecular graphs and spatial configurations.Researchers from The Hong Kong Polytechnic University, Shanghai Jiao Tong University, and Shanghai AI Lab have proposed TOMG-Bench (Text-based Open Molecule Generation Benchmark), the first comprehensive benchmark designed to evaluate LLMs capabilities in open-domain molecule generation. It introduces three major tasks: molecule editing (MolEdit), molecule optimization (MolOpt), and customized molecule generation (MolCustom), with each task further divided into three subtasks containing 5,000 test samples. Researchers also developed an automated evaluation system to evaluate the quality and accuracy of generated molecules. Through extensive testing of 25 LLMs, TOMG-Bench reveals crucial insights into current limitations in text-guided molecule discovery.The TOMG-Bench evaluation framework uses four distinct categories of models. The first category, proprietary models, includes commercial API-accessible systems like GPT-4-turbo, GPT-3.5-turbo, Claude-3.5, Claude-3, and Gemini-1.5-pro. The second category features open-source general LLMs with instruction-following capabilities, including various versions of Llama-3, Mistral-7B, Qwen2-7B, yi-1.5-9B, and chatglm-9B. The third category consists of LLMs fine-tuned on the ChEBI-20 dataset, including different versions of MolT5 and BioT5-base. The final category focuses on OpenMolIns fine-tuned LLMs, featuring Galactica-125M, Llama3.2-1B-Instruct, and Llama-3.1-8B-Instruct, with Galactica-125M being tested across five different data sizes of OpenMolIns.The evaluation results from TOMG-Bench show that Claude-3.5 emerged as the top performer with a weighted average accuracy of 35.92%, followed closely by Gemini-1.5-pro at 34.80%. Further, open-source models show remarkable progress, with Llama-3-70B-Instruct achieving 23.93% accuracy, outperforming GPT-3.5-turbos 18.58%. However, models trained specifically on the ChEBI-20 dataset show limited effectiveness, with BioT5-base, despite being the claimed state-of-the-art model for text-based molecule generation, achieving only 4.21% weighted average accuracy. These models particularly struggled with molecular editing operations and customized molecule generation tasks.In this paper, the researchers introduced TOMG-Bench, a benchmark for evaluating LLMs capabilities in open-domain molecule generation. Through comprehensive testing of 25 LLMs, the benchmark has effectively highlighted both the limitations of existing molecule generation approaches and the promising potential of general LLMs in this field. The successful implementation of OpenMolIns instruction tuning has shown remarkable improvements, enabling models to achieve performance levels comparable to GPT-3.5-turbo. However, it faces certain limitations, like insufficient prompt diversity which could lead to instruction overfitting, and potential inaccuracies in the distribution of molecular components such as atoms, bonds, and functional groups compared to real-world scenarios.Check out the Paper. All credit for this research goes to the researchers of this project. Also,dont forget to follow us onTwitter and join ourTelegram Channel andLinkedIn Group. Dont Forget to join our60k+ ML SubReddit. Sajjad Ansari+ postsSajjad Ansari is a final year undergraduate from IIT Kharagpur. As a Tech enthusiast, he delves into the practical applications of AI with a focus on understanding the impact of AI technologies and their real-world implications. He aims to articulate complex AI concepts in a clear and accessible manner. [Download] Evaluation of Large Language Model Vulnerabilities Report (Promoted)0 Kommentare 0 Anteile 26 Ansichten
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WWW.NINTENDOLIFE.COMSuper Mario Run Celebrates Super Mario Party Jamboree In New Crossover EventImage: NintendoTo celebrate the recent arrival of Super Mario Party Jamboree, Nintendo's mobile runner game Super Mario Run is hosting a special limited-time event.This includes three types of missions to participate in - including Rainbow Galleria Missions, Goomba Lagoon Missions, and King Bowser's Keep Missions. If you complete these missions you'll unlock special Mario Party-themed statues.Image: NintendoThese missions are active between now and 29th January 2025 and you can keep up to date on your progress by tapping the mission icon in the top-right area of your kingdom. This cross-over event in Super Mario Run follows a Mario & Luigi: Brothership event in November. All aboard!Family-friendly good times aheadSubscribe to Nintendo Life on YouTube789kWatch on YouTube Have you played Mario Run or the new Mario Party yet? Will you be checking out this latest event? Let us know in the comments.[source nintendo.com]Related GamesSee AlsoShare:00 Liam is a news writer and reviewer for Nintendo Life and Pure Xbox. He's been writing about games for more than 15 years and is a lifelong fan of Mario and Master Chief. Hold on there, you need to login to post a comment...Related Articles'Hyperdimension Neptunia' & 'Death End' Switch Releases Scrapped For "Not Complying With Nintendo Guidelines"Death end re;Quest: Code Z still on for PS5/4, thoughToby Fox Shares Another Development Update On Deltarune Chapter 3, 4 & 5"Progress has still been steady"'Switch 2' Is Projected To Be The "Clear Winner" In The Next Console GenerationWhile either Sony or Microsoft will "struggle mightily"0 Kommentare 0 Anteile 13 Ansichten
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WWW.NINTENDOLIFE.COMNintendo Announces The Final Tetris 99 Maximus Cup For 2024Update: The Zelda: Echoes of Wisdom event is now underway.The Legend of Zelda: Echoes of Wisdom has been one of the major highlights for the Switch this year, and to send 2024 out with a bang, Tetris 99's final Maximus Cup of the year will be all about this game!The 44th Maximus Cup will take place between 19th December and 23rd December, and if you participate and accumulate 100 points, you'll unlock a special theme.Read the full article on nintendolife.com0 Kommentare 0 Anteile 13 Ansichten
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WWW.ARCHITECTURAL-REVIEW.COMCompetition results: Finalists in Logroo climate island contest revealedThe four teams shortlisted in an international contest for a permanent new urban climate island installation in Felipe VI Park in Logroo, Spain have been revealedOrganised by local cultural festival Concntrico the two-stage competition sought proposals for a new urban climate island installation which offers thermal comfort and helps residents mitigate the challenges of rising local temperatures caused by the climate crisis.The finalists are 600 Trees by Carlos Portillo from Canada, A Stone at the Waters Edge by US-team clovisbaronian featuring Georgina Baronian and Sam Clovis, and Al agua patos by Spains K37.lab featuring Carlos Iraburu Elizalde, lvaro Oriol, Jos Rodrguez-Losada and Carlos Iraburu Bonaf.The shortlist is completed by Air Column by mft architects of Spain featuring Flavio Martella, Maria Vittoria Tesei withsnstudios Adrin Haibara and Vanessa Mingozzi. The shortlisted teams were picked from 252 proposals representing 49 countries which were submitted to the contest.Competition site: Felipe VI Park climate island, LogrooThe winning 80,000 installation will be constructed around a lake in the city centre Felipe VI Park on a stretch of terracing featuring a hexagonal square. Applicants were encouraged to use a range of measures such as shading structures, tree planting, water permeable soft natural soil and benches to help reduce temperature at specific points.Logroo, in northern Spain, is a historic city overlooking the River Ebro and is the capital of the Rioja wine-producing province.Earlier this year, the city hosted a series of contest-winning installations selected as part of an annual open call held by The Logroo International Festival of Architecture and Design also known as Concntrico.The festival has delivered more than 70 pop-up installations and pavilions across the centre of the historic city since it was founded in 2015.Competition site: Felipe VI Park climate island, LogrooThe latest competition set out to create a new permanent infrastructure at the western end of Felipe VI Park close to Hermanos Hircio, Ingeniero Pino and Amorena streets that helps local inhabitants mitigate the impact of increasing heat waves.The finalists will now be judged on their projects integration into the surrounding architectural and urban environment, versatility, material sustainability, promotion of circular economy and feasibility.The four teams will each receive 1,500 to participate in the second phase of the contest and the overall winner will receive a 10,000 prize. The competition organisers will be responsible for the production and construction of the winning proposal in coordination with the selected team.The shortlistShortlisted: 600 TREES by Carlos Portillo, Canada600 TREES by Carlos Portillo, CanadaThe project aims to transform 180m2 of urban space into a self-sustaining micro-forest. The proposal includes a raised ring with lighting and recycled rocks, creating an accessible and environmentally friendly space for visitors. This innovative proposal will promote carbon sequestration, urban cooling and biodiversity, providing shade and shelter for birds and insects. As the forest grows, trees will gradually cover the ring, symbolising the integration of nature into the urban space.Shortlisted: A Stone at the Waters Edge by clovisbaronian (Georgina Baronian, Sam Clovis), United StatesA Stone at the Waters Edge by clovisbaronian (Georgina Baronian, Sam Clovis), United StatesThe proposal uses the architecture as a thermal battery, taking advantage of the materials properties without mechanical systems to cool the environment. A ventilated void between two layers of concrete reduces embodied carbon and allows passive cooling through a night ventilation system. Recycled concrete and the use of site soil as a mould ensure durability, reduce waste and create a unique structure that integrates into the waterscape.Shortlisted: Al agua patos by K37.lab (Carlos Iraburu Elizalde, lvaro Oriol, Jos Rodrguez-Losada, Carlos Iraburu Bonaf), SpainAl agua patos by K37.lab (Carlos Iraburu Elizalde, lvaro Oriol, Jos Rodrguez-Losada, Carlos Iraburu Bonaf), SpainThe aim of the project is to create a climatic island that revitalises a unique space and encourages interaction with the natural environment. It will be structured in three elements: two main layers and a boundary connecting them, forming a central garden with vegetation adapted to the climate. A modular pergola will provide shade and, together with an interactive and accessible pond, the aim is to reactivate and breathe new life into this space, inviting the community to enjoy it.Shortlisted: Air Column by mft architects (Flavio Martella, Maria Vittoria Tesei) + snstudio (Adrin Haibara) + Vanessa Mingozzi, SpainAir Column by mft architects (Flavio Martella, Maria Vittoria Tesei) +snstudio(Adrin Haibara) + Vanessa Mingozzi, SpainThe functioning of the project is based on the principle of the solar chimney, a natural system that uses solar energy to trigger convective movements. Inside the semi-transparent column, the suns rays heat the air and cause it to rise. This movement creates a depression at the base that draws in fresh air, generating a constant natural breeze.0 Kommentare 0 Anteile 12 Ansichten
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WWW.FORBES.COMTodays NYT Mini Crossword Clues And Answers For Sunday, December 22Mini CrosswordNYTIn case you missed Fridays NYT Mini, you can find the answers here:The NYT Mini is a quick and dirty version of the newspaper's larger and long-running crossword. Most days, there are between three and five clues in each direction on a five by five grid, but the puzzles are sometimes larger, especially on Saturdays.Unlike its larger sibling, the NYT Mini crossword is free to play on the New York Times website or NYT Games app. However, youll need an NYT Games subscription to access previous puzzles in the archives.The NYT Mini is a fun daily distraction that usually takes no time at all. I try to beat the standard weekday grid in less than a minute. But sometimes I can't quite figure out one or two clues and need to reveal the answer.To help you avoid doing that, here are the NYT Mini Crossword answers (spoilers lie ahead, of course):MORE FOR YOUNYT Mini Crossword Clues And AnswersACROSS1) Longtime first name in the House of Representatives - NANCY6) Word that aptly fills in these blanks: S_ _rano's p_ _form_nce - OPERA7) Bad thing to go up without a paddle - CREEK8) Assistant - AIDE9) Toilet paper layer - PLYDOWN1) "For real!," in popular slang - NOCAP2) When Tax Day is - APRIL3) Requiring a lot of attention - NEEDY4) Indigenous people of Canada - CREE5) Beast also known as a "grunting ox" - YAKNYT MiniNYTWell, I never thought I would see the day when No cap would be in a New York Times crossword puzzle, but here we are. If you are the type of person who looks up crossword puzzles answers, I imagine you might not have known that one. Otherwise, the Opera clue was clever. I thought it was Kree, not Cree, because I have been watching too many Marvel movies.Follow me on Twitter, YouTube, and Instagram.Pick up my sci-fi novels the Herokiller series and The Earthborn Trilogy.0 Kommentare 0 Anteile 25 Ansichten
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GAMERANT.COMBest Touring Cars In The Crew 2The Crew 2 offers several racing disciplines, including elite touring events requiring specially tuned racing cars. In these demanding and lengthy races, stats like acceleration, handling, and top speed are crucial. Most touring-ready cars in the game can easily hit top speeds of 200 mph in under 20 seconds.0 Kommentare 0 Anteile 15 Ansichten