One of five houses built by developer Albert Jewell along Powell Street in the Cottage Farm neighborhood of Brookline, this residence stands out for its materiality and stately design. The house was designed by J. Williams Beal, an architect who trained at Massachusetts Institute of Technology and then worked for McKim, Mead & White before opening his own business. The house was first purchased from Mr. Jewell by Grace and Edwin Kramer, who worked as superintendent for R. H. White & Co., the large dry goods store in Boston. The next long-term owner was Harry B. Duane, a wealthy grocer. The Kramer-Duane House is unique for the stone veneer at its facade, gambrel roof covered in slate, and varied window styles including: bay windows, dormer windows, and an eyebrow dormer window at the roof.