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Phase I trial of hES cell-derived dopaminergic neurons for Parkinson’s disease
Nature, Published online: 16 April 2025; doi:10.1038/s41586-025-08845-yBilateral grafts of cryopreserved human embryonic stem cell-derived dopaminergic neuron progenitor cells into the putamen of patients with Parkinson’s disease in a phase I clinical trial showed safety, improvements in off-drug motor function and graft survival at 18 months after transplant.
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