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Cellular ATP demand creates metabolically distinct subpopulations of mitochondria
Nature, Published online: 06 November 2024; doi:10.1038/s41586-024-08146-wMitochondria are able to maintain two competing metabolic pathwaysoxidative phosphorylation and the reductive synthesis of proline and ornithineby generating two mitochondrial subpopulations that are enriched in either pyrroline-5-carboxylate synthase or ATP synthase.
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