Secret of Secrets is a mystery youll find as you explore Indiana Jones and the Great Circles Vatican. Youll be able to find it once you reach the Sistine Chapel. The safe and all the clues are located in a small office off the west end of the chapel. Our Indiana Jones and the Great Circle guide will show you how to find the Secret of Secrets safe code.How to start the Secret of Secrets mysteryOnce you reach the Sistine Chapel, youll be able to access the Secret of Secrets safe. Head to the west end of the chapel and look for the door to the left of the altar. Head into that office.Secret of Secrets cluesAs soon as you walk in, look to the right to find Nicolettis Note. Thatll start the mystery.The safe youre going to open is to the left, but there are other clues to find first. Head to the desk and open the drawer to find a Planetary Chart. This is where youll get the numbers for the safe combination.The remaining clues are the statues of Saints Peter and Paul. Peter is in the corner to the left of the desk. Paul is right next to the safe.The statues themselves arent the clues. Youll need to use the right thumbstick to rotate the statue until you can see the bottom.Secret of Secrets safe code solutionNicolettis Note tells you the order to look at the statues Peter first, and then Paul to get the planetary symbols. Theyll be upside down, but they are , , , and or Mars, Mars, Uranus, and Mercury.If you look at the Planetary Chart note, youll see the planets are numbered from bottom to top. The symbol for Mars is missing, but its in the fourth orbit (where youd expect).That makes the safe combination 4471. Inside, youll find a Cutman 1 adventure book, a Hidden Note, and a forged book. You can take the book with you, but theres nothing to do with it.For more Indiana Jones and the Great Circle guides, heres a running list of safe codes. We also have solutions for many puzzles in the Vatican, including the Belvedere Courtyard, the Fountain of Confession, Father and Son, A Date to Remember, Bulls of Blood, House of God, and A Free Spirit, plus guides to Strange Inscription and Vatican Ancient Relic locations.