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RNA control of reverse transcription in a diversity-generating retroelement
Nature, Published online: 08 January 2025; doi:10.1038/s41586-024-08405-wThis study presents cryogenic electron microscopy structural analysis of a diversity-generating retroelement (DGR) reverse transcription system from Bordetella bacteriophage, with results indicating that RNA surrounding the template controls reverse transcription through mechanisms that are conserved across distant taxa.
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