Precise modelling of mitochondrial diseases using optimized mitoBEs

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2025-01-24 04:42:56 ·

www.nature.com

Nature, Published online: 22 January 2025; doi:10.1038/s41586-024-08469-8A study reports optimized mitochondrial base editors with reduced off-target effects to facilitate the generation of mouse models of human mitochondrial diseases.

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