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WWW.ZDNET.COMHow we test laptops at ZDNET in 2025Kyle Kucharski/ZDNETWe test dozens of laptops every year here at ZDNET, and our testing process employs a dual approach. On one hand, we run a series of benchmarking programs to gather important system data and metrics. On the other hand, we approach laptops the way any normal consumer would, considering ease of use, form factor, durability, and battery life.Also: The best laptops: Expert tested and reviewedOur core testing philosophy is simple: while it's imperative to gather data, numbers aren't the whole story. Laptops can be very personal, and as such, there's an intuitive, human element that can't be ignored, and we take that into account while writing our reviews.How we test laptops in 2025 Kyle Kucharski/ZDNETYou only get one first impression, and when we get a new laptop to review, we always take note of initial perceptions before diving into the data. Upon setting up the laptop's operating system, connecting to Wi-Fi, and logging in with any relevant credentials, we take note of how smooth the startup process was. Was it quick and painless? Or was there a lot of clicking to get through all the product offers and bloatware? (Windows 11, I'm looking at you.)We give all the devices we test equal footing by starting with the most recent updates to the device's operating system, as well as all relevant drivers for the GPU, BIOS, and hardware. It can be easy to skip over these updates, but you don't need me to tell you that not updating your computer can result in some bizarre behavior.The core components of a laptopThese are the most important core system metrics we look at during the testing process:The processor (CPU): This is the "brain" of the laptop, and one of the most important factors that determines performance. The four biggest manufacturers that make most of the CPUs found in laptops today are Intel, AMD, Qualcomm, and Apple (in their own machines only).RAM: Random access memory acts as your computer's short-term memory and is involved in multitasking as you edit documents, run multiple apps, and most importantly -- browse the web. The amount of RAM your computer has is measured in gigabytes (GB) and starts at 8GB, and goes up to 32GB and beyond.Storage: Also measured in gigabytes (GB) or terabytes (TB), where one terabyte equals around 1,000 gigabytes. This is the storage bank where your computer's files, documents, photos, and videos are saved. Most laptops these days have at least 128GB of storage, where some go up to 1, 2, or more terabytes.The graphics processor (GPU): Whether it's integrated into the CPU or a dedicated graphics card, how well the machine handles graphics is a key factor when it comes to demanding visual tasks like video editing, rendering, and of course, gaming.The display: The size of the display (measured diagonally from corner to corner) is also what dictates the laptop's overall size, and almost always included in the model's name. Displays run the gamut, as they often play a big role in the laptop's cost. On lower-end machines, you'll find lower brightness (measured in "nits") and lower resolutions. Higher-end laptops often feature OLED displays, which are often the most visually pleasing, along with high refresh rates (120Hz and above).Port selection: Different folks will have different needs when it comes to ports. We always identify what's available and how the port selection aligns with the device's targeted use case.Physical form factor:Finally, the laptop's overall appearance and physical form factor encompasses its weight, thickness, how the keyboard and trackpad feel, and whether or not it has a display that can be folded back to form a tablet or touchscreen.What makes a laptop ZDNET Recommended?Obviously, more factors go into a laptop's final review other than being simply "good" or "high-performing." Yes, feature sets are ultimately subjective, but we recommend a laptop when it fulfills the following requirements:Expectation:First and foremost, does the laptop perform how it's meant to? If a laptop is marketed to be a gaming machine, how well does it run high-end games? If it's a laptop designed for creators, does it handle video and photo editing efficiently? Understanding what a laptop is designed for -- and how well it executes on that niche -- goes a long way to being recommended. Value:A laptop's value is more than just how good its price looks. A more accurate way to gauge its value is by considering how well it performswithinits price point. A $500 laptop should look and feel like a $500 laptop. Much like how a $1,000 laptop should feel like it's twice as fast. We give extra attention to laptops that perform above their price point.Performance:There's no need to beat around the bush. When it comes down to it, highly recommended laptopsperform. They're fast, efficient, and easy to use. Whether that means browsing the web with ease on a $300 Chromebook or rendering 4K video projects in a top-of-the-line MacBook Pro, the scale is different, but the core idea is the same: high performance is key.Excellence:A highly recommended laptop should punch above its weight in multiple areas. We want to highlight laptops that don't just meet the bar but exceed it, either in design, battery life, display, performance, or value.Benchmarking and system data Kyle Kucharski/ZDNETIn order to gather detailed information about the laptop, we run a few different diagnostics programs that provide at-a-glance summaries for its hardware and software. There are quite a few programs out there that can do this:SiSoftware Sandrais one such reliable program, as well asGPU-Z, which provides all the detailed information you could ever want about your computer's graphics processor.We then run a series of benchmarking tests to put the computer's hardware through the wringer in order to see what they're capable of.Cinebenchis one of the most commonly used hardware testing suites, which tests the laptop's rendering performance on single and multiple CPU cores, and then compares these numbers against other machines.PCMark 10is another powerful benchmarking suite that covers a wide variety of tasks performed in the modern workplace.Also: The best OLED laptops: Expert tested and reviewedGeekbenchis another industry standard testing program that provides a numerical score for your laptop's processor's performance in a variety of different use case categories. For example, how well the CPU handles common everyday tasks such as file compression, navigation, and browsing in its productivity workload, as well its developer and machine learning workloads.Other benchmarking software applications we regularly use include3DMark, which tests the laptop's graphics performance, (particularly important with gaming laptops), andJetStream2, a browser-based benchmarking tool we run on Chromebooks.After completing a variety of metric-oriented testing, we then compare the results of the tests up against the manufacturers' claims. In most cases, the data is close to the advertised numbers, but every once in a while we'll see some outliers that prompt additional investigation or testing, noting this in the device's final review.Finally, depending on any niche use cases, we can test the laptop's performance further in specific areas. For example, if a machine is geared toward creators, we will run photo and video editing software, while testing a gaming laptop wouldn't be complete without firing up a handful of games.In these scenarios, we pay close attention to the performance of the laptop's GPU, how the display handles rendering tasks, and performance while multitasking while running select performance testing software.How we test laptop batteries Kyle Kucharski/ZDNETBattery life is one of those things that all consumers care about. Regardless of what kind of device you're using, and whether it's $300 or $3,000, if your laptop is dead, it's useless.We approach testing a unit's battery in largely the same way. Basically, the idea is to let the laptop run for as long as it can under a medium load. First, we ensure screensavers and hibernation mode are turned off, as well as any battery-saving performance mode (although running tests in that mode is also valuable; it's just a separate test).Also: The best battery life laptops: Expert tested and reviewedWe then set the display's brightness and audio at 50%, turn off any RGB or keyboard backlighting, load up a livestream on YouTube in Chrome, set a timer, and wait 'til the end. In my experience, battery life is one of those metrics that has changed a lot within the past few years, and it keeps getting better. With new advancements with AI-powered chips, battery life has exploded into heights that just a few years ago would have been considered nigh impossible.With this in mind, putting every laptop we review to the test is more important than ever, to get to the bottom of manufacturers' sometimes "ambitious" claims.The human element Kyle Kucharski/ZDNETAs we mentioned earlier, metrics and system data is important, but numbers alone don't give you the full picture. This is where we weave in our personal experience with the device and tap into the practical use cases that consumers actually care about.Laptop manufacturers always have a specific demographic in mind when they design a new model, so this is where knowledge of that marketing aspect comes into play. If a computer is designed specifically for video and photo editors, how well do industry-standard programs like Adobe Photoshop, Premiere Pro, and OBS actually run?Also: The best lightweight laptops: Expert testedFor productivity-focused laptops, how long do their batteries last? Can they multitask on three monitors as well as they advertise?Ultimately, our goal here is to break down the capabilities of each and every laptop we test into digestible terms that real people can find useful. There is a lot of noise and confusion when it comes to navigating the laptop and computer consumer market, so we hope to bring an intuitive element to the whole process by leveraging our team's decades of experience.ZDNET Recommends0 Reacties 0 aandelen
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WWW.FORBES.COMThe Coming Year: GenAI Enters The Roll-Up-Our-Sleeves-And-Get-To-Work PhaseTime for AI to prove itselfGettyAnecdotally, its being said, at least anecdotally, that the AI hype has been cooling as of late. Gartner, the consultancy that devised its oft-quoted hype cycle, agrees.GenAI has passed the Peak of Inflated Expectations, wrote Afraz Jaffri, analyst with Gartner, in a bulletin published in November. By the end of 2024, value will be largely derived from projects based on familiar AI techniques, either stand-alone or in combination with GenAI, that have standardized processes to aid implementation. In other words, time to get past the shiny-new-thing stage to roll up ones sleeves and make it all work.Industry leaders agree that its time for the hard and purposeful work to begin. While there is a lot of hype around AI, we have seen impressive outcomes in such a short span of time, said Sri Elaporu, global head of the AWS Generative AI Innovation Center. Companies are already seeing real benefits of generative AI."There is certainly a lot of hype and potentially unrealistic expectations around AI, especially generative AI, in the short run," said Steve Chase, vice chair of AI and digital innovation at KPMG. "This can put unrealistic pressure on teams to deliver immediate results and cause doubts about continuing investments when those lofty expectations are not met right away. However, many companies are already seeing tangible benefits from AI. The mid to long-term potential of AI is likely understated."Elaporu pointed to some large customers his organization is working with, and how they are gaining ground with targeted genAI projects. For instance, Rocket Mortgage Americas largest retail mortgage lender leveraged genAI built using Amazon Bedrock to improve the path to homeownership and clients have seen a 10% increase in resolutions during their first call to Rocket, he said. Another client. Bayer, is also using genAI to accelerate and re-envision the development of food across Bayers 120 million acres of growing fields.KPMG is working with its clients to implement AI solutions across various functions, such as marketing, sales, customer service, field service, procurement, and software development, Chase said. In highly regulated industries we are helping clients use AI to process large quantities of written content to produce structured and repeatable summarized documents think rate cases for utilities or required product labeling in life sciences.MORE FOR YOUAt its core, both operational and generative AI require human input. At KPMG, we've observed that the primary challenges companies face in genAI adoption are engaging employees, helping them understand the benefits of the technology, and keeping pace with the rapid advancements in the field, Chase said.There's often a gap between leaders' enthusiasm for the disruption that genAI brings and the concerns of employees who are nervous about what the technology might mean for them, especially as it evolves quickly, he added.Enterprises express concern about AI around data privacy, integration with existing systems, model selection, and the skill gaps, Elaporu observed. However, the first stepknowing how and where to startis often the most significant barrier to entry. He stated that moving from proof of concept to a productized service is the most difficult step to generative AI adoption.Chase advocates a human-centric approach to AI to deliver working value. This involves focusing on robust change management, training, and communication efforts, he says. Engaging with employees requires connecting with them on an emotional level, using storytelling techniques to share examples of how the technology can be used and celebrating successes.Reskilling is also critical, as many companies lack the necessary skills to fully leverage AI technology, Chase continued. We have also found that adoption occurs faster when AI capabilities are embedded into the tools or workflows that employees are already using, rather than requiring them to navigate to another system.0 Reacties 0 aandelen
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WWW.DIGITALTRENDS.COMThis handset just won an award for least durable smartphone of 2024Smartphone DURABILITY Awards 2024!Zack Nelson of the popular YouTube channel JerryRigEverything has just announced his least and most durable phones of 2024.Recommended VideosNow, as anyone whos watched his videos will know, Nelson knows a thing or two about phone durability. Over many years, in the name of research, hes scratched, scraped, burned, and bent a slew of new smartphones to see how they fare. And usually, the result is not pretty.Please enable Javascript to view this contentSpeaking at a table full of phones and tablets wrecked by Nelson over the last 12 months, the tech YouTuber reaches for the triple-folding Huawei Mate XT as his least durable handset of 2024. He chose it because not only does it have the super-soft center screen, but that center screen is exposed to the outside world when its closed. It also sucks up rocks and dust like a hoover, but that screen, which we already know scratches [easily], is like walking around with a raw egg in your pocket. He acknowledged that the handsets design is super cool but added that its most definitely not super durable.RelatedIn the original video featuring the Mate XTs bend test, Nelson notes how the phone actually includes sensors that vibrate to notify you if youre bending any of the three folds in the wrong direction. This is the first phone to beg for its life during the bend test, Nelson quipped just before snapping the far left display with a wince-inducing crack.As for the most durable smartphone of 2024, well, that went to the extraordinarily rugged Armor 24, which Nelson suggested has enough built-in protection to survive a steamroller. The Armor 24 is like a brick, and so there was zero possibility of Nelson snapping this thing in two. To find out which two phones he selected as runners-up in the most-durable category, and which handsets won out in the most/least repairable category, check out Nelsons video at the top of this page.Editors Recommendations0 Reacties 0 aandelen
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WWW.BUSINESSINSIDER.COMOnly 11 movies received a perfect score on Rotten Tomatoes this year — here they all are"All We Imagine as Light""All We Imagine as Light" was written and directed by Payal Kapadia. Janus Films Number of reviews: 124What it's about: "All We Imagine as Light," written and directed by Payal Kapadia, is set in Mumbai and follows Prabha (Kani Kusruti) and Anu (Divya Prabha), two nurses and roommates, and Parvaty (Chhaya Kadam), their coworker who's a cook at the hospital. The film explores the power of friendship among the three women as they navigate personal challenges, from affairs to eviction.Why you should watch: Critics are enchanted by Kapadia's second feature film, calling it "dreamlike," "luminous," and a "sensual triumph." The movie feels like an ode to Mumbai, where the bustling city is captured so vibrantly that it becomes a character in the narrative, too."All We Imagine as Light" premiered at the 2024 Cannes Film Festival earlier this year, where it won the prestigious Grand Prix award.Where to watch: In select theaters.Watch the trailer for "All We Imagine as Light" here. "Daughters""Daughters." Netflix Number of reviews: 65What it's about: "Daughters" is a documentary from filmmakers Natalie Rae and Angela Patton about a group of girls getting ready for a dance with their incarcerated dads. For some of them, it will be the only physical contact that they have with their fathers while they serve their prison sentences.Why you should watch: Critics called "Daughters" emotionally moving, providing a grounded view into what it's like having a family member in prison. Some praised the film for focusing on, and humanizing, its subjects."Daughters" earned two awards at the 2024 Sundance Film Festival, where it premiered: festival favorite and audience choice: U.S. documentary competition.Where to watch: Netflix "Nowhere Special"James Norton in "Nowhere Special." Lucky Red Number of reviews: 63What it's about: "Nowhere Special" centers on John (James Norton), a 35-year-old window cleaner and single dad who is raising his 4-year-old son Michael (Daniel Lamont) after the kid's mom leaves following his birth. When John learns that he has a few months left to live, he becomes determined to prepare his son for his death and find a new family for him.Why you should watch: Uberto Pasolini's drama, originally released in 2021 before getting a US theatrical release this year, is an understated and tender look at life and death. Critics say Norton's performance as a father dying of brain cancer is tear-inducing, and his young costar Lamont shows signs of a promising future as an actor. Despite its heartbreaking premise, "Nowhere Special" maintains a hopeful outlook.Where to watch: Available to rent or buy on Prime Video and Apple TV+.Watch the trailer for "Nowhere Special" here. "Jim Henson Idea Man"Young Jim Henson working on Kermit the Frog. Imagine Documentaries/Disney Number of reviews: 60What it's about: This documentary, from Academy Award-winning director Ron Howard, follows Jim Henson's storied career, from the Muppets franchise to films like "The Dark Crystal" and "Labyrinth." The film includes footage from Henson's archives, as well as interviews with prior collaborators and family members.Why you should watch: Critics praised the documentary as capturing Henson's spirit without sanitizing his life. Some wrote that while Howard takes a fairly straightforward biographical approach, it works well for Henson as a subject."Jim Henson Idea Man" premiered at the 77th Cannes Film Festival in the "Cannes Classics" section. It won five Emmy awards, including outstanding documentary or nonfiction special and outstanding motion design.Where to watch: Disney+ "Sugarcane"Julian Brave NoiseCat and his father Ed Archie NoiseCat in "Sugarcane." Emily Kassie/Sugarcane Film LLC Number of reviews: 57What it's about: Directed by Julian Brave NoiseCat and Emily Kassie, "Sugarcane" follows the aftermath of unmarked graves being discovered near an Indian residential school in Canada that was run by the Catholic Church and closed in 1981. The film tracks a Williams Lake First Nation investigation into abuse and missing children at St. Joseph's mission.Why you should watch: Critics praised the film as empathetic, sensitive, and in some cases, "devastating." Some praised the film for the way depicts the aftermath of tragedy and injustice.The film won the U.S. documentary directing award at the 2024 Sundance Film Festival, where it premiered. It has also received documentary film awards at the Sarasota Film Festival, the San Francisco International Film Festival, and from the National Board of Review, among others.Where to watch: Hulu, Disney+ "Girls Will Be Girls"Preeti Panigrahi as Mira in "Girls Will Be Girls." Prime Video Number of reviews: 53What it's about: The coming-of-age Indian film stars Preeti Panigrahi as Mira, a 16-year-old girl constrained by the rules of her boarding school and her strict mother when she develops a connection with a new student named Srinivas (Kesav Binoy Kiron) and expresses interest in exploring her sexuality and desires.Why you should watch: Critics call "Girls Will Be Girls" a stellar debut for first-time feature filmmaker Shuchi Talati, who also wrote the script. Many agree that the movie tackles typical coming-of-age themes with a cultural specificity that makes "Girls Will Be Girls" stand out from the myriad of other existing films in the genre.The protagonist's intimate journey is examined with sensitivity and quiet moments that let the cinematography and scene composition do all the talking.""Girls Will Be Girls" earned the audience award in the world cinema dramatic category at the 2024 Sundance Film Festival.Where to watch: Available to rent or buy on Prime Video.Watch the trailer for "Girls Will Be Girls" here. "No Other Land""No Other Land." Antipode Films Number of reviews: 49What it's about: Directed by Basel Adra, Hamdan Ballal, Yuval Abraham, and Rachel Szor, "No Other Land" is a documentary about Palestine and Israel. It follows the Israeli destruction of Palestinian homes and schools in Masafer Yatta, a group of West Bank villages that Adra calls home. The four directors hail from Palestine and Israel, and filmed over the course of four years.Why you should watch: Critics described "No Other Land" as "essential," important, and emotionally affecting viewing.The film has picked up dozens of film festival and critic awards, including the Berlinale documentary film award and Panorama audience award for best documentary film at the Berlin International Film Festival, and best documentary and non-fiction film awards from Los Angeles, Boston, and New York critics groups, among others.Where to watch: "No Other Land" is available to purchase or rent in some regions, though it does not yet have distribution in the United States. "I Am: Celine Dion"Dion in her documentary. Amazon Studios Number of reviews: 46What it's about: This documentary, directed by Irene Taylor, tracks Dion's diagnosis with stiff-person syndrome, a condition that causes the muscles to stiffen involuntarily. The documentary includes archival footage from Dion's storied career, and follows her through her diagnosis, treatment, and desire to return to the stage.Why you should watch: Critics called the documentary "raw," doing justice to Dion's legendary career while humanizing her as as a subject. Adrian Horton of the Guardian called the film "unabashedly sentimental" and "deeply earnest."Where to watch: Prime Video "On Becoming a Guinea Fowl""On Becoming a Guinea Fowl" was written and directed by Rungano Nyoni. A24 Number of reviews: 46What it's about: The A24 dark comedy stars Susan Chardy as Shula, a woman who discovers her Uncle Fred's body on the road one night. With the dayslong funeral proceedings underway, she must confront the secrets of her middle-class Zambian family.Why you should watch: Critics say the film is compelling and intriguing, with a script that deftly balances its serious subject material with moments of humor. Many have also praised Nyoni's sharp directing style and her exploration of the political, cultural, and social facets of Zambian life.Where to watch: "On Becoming a Guinea Fowl" is currently not available to stream. It will be released in limited theaters on March 7.Watch the trailer for "On Becoming a Guinea Fowl" here. "Music By John Williams"Legendary composer John Williams conducting. Carlo Allegri/Getty Images for LAPA Number of reviews: 45What it's about: Directed by Laurent Bouzereau, "Music By John Williams" examines the storied composer's career and work across multiple franchises. The film features interviews with people like Steven Spielberg, who worked with Williams on films like "Jaws" and "E.T.," and George Lucas, creator of "Star Wars" and "Indiana Jones."Why you should watch: Critics wrote that the film was a fitting tribute to Williams and a lovely celebration of his work. Some praised the film's depiction of Williams' relationships with filmmakers, including Spielberg and Lucas."Music By John Williams" won the award for best music documentary at the Critics Choice Documentary Awards.Where to watch: Disney+Watch the trailer for "Music By John Williams" here. "LaRoy, Texas"Steve Zahn in "LaRoy, Texas." Brainstorm Media Number of reviews: 42What it's about: The comedy, written and directed by Shane Atkinson, stars Steve Zahn as a private detective named Skip and John Magaro as Ray, a man who becomes depressed after he learns that his wife is cheating on him. As Ray is about to shoot himself with a gun and end his life, his life takes a wild turn when he gets mistaken for a hitman and becomes involved in an assassination plan.Why you should watch: Critics say that Atkinson's feature directorial debut is an entertaining thrill ride, toeing the line between believable absurdity and over-the-top shenanigans. The influence of and nods to the filmmaking brothers Joel and Ethan Coen are plentiful, and the movie is bolstered by a solid cast comprised of Magaro, Zahn, and Dylan Baker."LaRoy, Texas" won three major prizes at the 49th Deauville American Film Festival: the Grand Prize, the Audience Award, and the Critics Award.Where to watch: Available to rent or buy on Prime Video and Apple TV+. Also available to stream on MGM+.Watch the trailer for "LaRoy, Texas" here.0 Reacties 0 aandelen
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WWW.ARCHDAILY.COMBus-Metro Line Shelters for 'Boavista-Imprio / lvaro Siza VieiraBus-Metro Line Shelters for 'Boavista-Imprio / lvaro Siza VieiraSave this picture! Pedro CardigoBus StationPorto, PortugalArchitects: Tiago Figueiredo, lvaro Siza VieiraAreaArea of this architecture projectArea:360 mYearCompletion year of this architecture project Year: 2024 PhotographsPhotographs:Pedro CardigoMore SpecsLess SpecsSave this picture!Text description provided by the architects. I was invited to this project by Metro do Porto and, initially, I did not accept because I understood that the basic layout would leave the avenue with only one lane for automobiles and I disagreed with the proposal for a roundabout at the junction of Av. Marechal Gomes da Costa with Av. da Boavista.Save this picture!Later, we were informed that the metro line would be shared with other buses and cars, and that a new roundabout would no longer be built, maintaining the linear axis of Av. da Boavista all the way to the sea.Save this picture!At the same time, the Serralves Foundation expressed interest in having me accept the design of the station since it is located in its nearby surroundings, in front of the existing wall surrounding the Serralves gardens and museum.Save this picture!We therefore accepted the project, requesting that it extend to include the three stations: Serralves, Joo de Barros, and Imprio, proposing their location along Av. Marechal Gomes da Costa, situated among the existing trees in the central green space and connected by a pedestrian path made of gravel.Save this picture!This was the executed project, which is now practically completed.The particular unified atmosphere of Av. Marechal Gomes da Costa, with a low-density residential program throughout, led to the decision not to consider the stations and shelters with the usual metal and glass solution, but to opt for a design in which the stations are integrated and relate to this urban context.Save this picture!Save this picture!Save this picture!Particular care was taken with the central pedestrian path and its connection to the three stations, the landscaping, and its variations.Porto, December 9, 2024lvaro SizaSave this picture!Project gallerySee allShow lessProject locationAddress:Porto, PortugalLocation to be used only as a reference. It could indicate city/country but not exact address.About this officelvaro Siza VieiraOfficeTiago FigueiredoOfficePublished on January 01, 2025Cite: "Bus-Metro Line Shelters for 'Boavista-Imprio / lvaro Siza Vieira" [Abrigos da Linha de Metro-Bus Boavista-Imprio / lvaro Siza Vieira] 01 Jan 2025. ArchDaily. Accessed . <https://www.archdaily.com/1025165/bus-metro-line-shelters-for-boavista-imperio-alvaro-siza-vieira&gt ISSN 0719-8884Save!ArchDaily?You've started following your first account!Did you know?You'll now receive updates based on what you follow! Personalize your stream and start following your favorite authors, offices and users.Go to my stream0 Reacties 0 aandelen
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WWW.NATURE.COMTimely TGF signalling inhibition induces notochordNature, Published online: 18 December 2024; doi:10.1038/s41586-024-08332-wThrough analysis of developing chick embryos and in vitro differentiation of embryonic stem cells, a study develops a method to generate a model of the human trunk with a notochord.0 Reacties 0 aandelen
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WWW.NATURE.COMSea ice is shrinking during Antarctic winter: heres what it means for Earths oceans and atmosphereNature, Published online: 18 December 2024; doi:10.1038/d41586-024-04078-7The extent of Antarctic sea ice dropped precipitously in 2023. Analysis shows that this decline has increased the transfer of ocean heat to the atmosphere in turn affecting ocean circulation and the frequency of storms.0 Reacties 0 aandelen
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WWW.NATURE.COMEngineered extrachromosomal oncogene amplifications promote tumorigenesisNature, Published online: 18 December 2024; doi:10.1038/s41586-024-08318-8Large extrachromosomal DNAs are engineered using a CRISPR- and CreloxP-based approach and shown to drive cancer in mouse models, with potential applications in determining the role of oncogene amplifications in human cancers.0 Reacties 0 aandelen
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