Approximately one-third of American adults take a multivitamin in an effort to address nutritional deficiencies or specific dietary needs. While they are an option to replace nutrients you may not be getting from food, it is worth mentioning that multivitamins vary in quality and dosage amounts.However, not everyone is able to receive the maximum benefit regular multivitamins offer. For a variety of reasons, a better option may be methylated multivitamins.What Is a Methylated Vitamin?When a vitamin is methylated, it means that methyl groups have been added to them. This makes the vitamins available for digestion in their active form. Known as CH3, a methyl group comprises three hydrogen atoms bonded to one carbon atom. Since they already have the methyl groups attached, the body can more easily absorb and utilize these vitamins.One of the most common forms of these multivitamins is B vitamins. This includes vitamins B12 (methylcobalamin), B9 (methylfolate), B6 (pyridoxal 5-phosphate), and B2 (Riboflavin-5-Phosphate). It is important to note that not all methylated multivitamins include all varieties of B vitamins. Various manufacturers offer different combinations and dosage amounts.Aside from improved absorption, methylated multivitamins can offer other advantages. These include the production of neurotransmitters, which can lead to improved mood and cognitive function support. Methylated B vitamins can also reduce fatigue by converting food into usable energy. Another important role for methylated vitamins is lowering homocysteine levels in the blood. Since high levels of homocysteine are linked to heart disease, methylated vitamins support cardiovascular health.Benefits From Methylated MultivitaminsFor people who do not have a problem converting regular vitamins into their active form or absorbing them, methylation will probably not have much of an impact. But methylated multivitamins can help certain individuals.These include people with gastrointestinal conditions where malabsorption is a factor, people with the MTHFR genetic mutation, athletes, pregnant people (confirm with doctor), and the elderly as the body does not absorb nutrients as well as we age. Methylated vitamins do not automatically provide added benefits but are useful for those needing the bioavailability of methylation.As with any supplement, it is best to select a brand that undergoes third-party testing to ensure safety and accuracy. It is also important to be aware of all the vitamins and/or minerals that are included when selecting a methylated vitamin. There may be added ingredients that you do not need or want, or the dosages of methylated B vitamins may be too high. You can find methylated multivitamins in capsules, pills, and gummies.Side Effects Associated With Methylated MultivitaminsThere are potential side effects with methylated multivitamins, either from taking them too much or too often. Since a multivitamin will include several B vitamins in their methylated form, it may not be possible to know which specific vitamin is causing side effects if or when they occur. Be aware that non-methylated B vitamins have the potential to cause these same side effects which include anxiety, agitation, irritability, headaches, nausea, neuropathy, insomnia, and achiness.Methylated multivitamins may also interact with certain medications and can cause negative health impacts. Patients should check with their healthcare provider before starting methylated multivitamins if they are taking any of the following: diabetes medications, anti-seizure drugs, certain antibiotics, and medicines that reduce stomach acid.People with a history of seizure disorders, liver issues, bipolar disorder, or pernicious anemia should consult with their doctor before taking a methylated multivitamin.This article is not offering medical advice and should be used for informational purposes only.Article SourcesOur writers at Discovermagazine.com use peer-reviewed studies and high-quality sources for our articles, and our editors review for scientific accuracy and editorial standards. Review the sources used below for this article:Britannica. MethylationThe Nutrition Source. B VitaminsDrugs.com. L-Methyl-B6-B12 InteractionsAllison Futterman is a Charlotte, N.C.-based writer whose science, history, and medical/health writing has appeared on a variety of platforms and in regional and national publications. These include Charlotte, People, Our State, and Philanthropy magazines, among others. She has a BA in communications and an MS in criminal justice.

NewsHealth & MedicineIs alcohol linked to cancer? Heres what the science saysA new report aims to help people make informed decisions about whether and how much to drink A new U.S. Surgeon Generals report seeks to raise awareness about the link between drinking alcohol and developing seven different types of cancer. Many Americans don't know of the risk.urbazon/E+/Getty Images PlusBy Aimee Cunningham1 hour agoThe link between drinking alcohol and developing cancer, described in a new report by the U.S. Surgeon General, may come as a surprise to many Americans.Although evidence for this link has been growing for some time, fewer than half of Americans are aware of the association, according to the 2019 Cancer Risk Awareness Survey. Thats in contrast to tobacco, which 89 percent of the survey respondents identified as a cancer risk.The Surgeon Generals Advisory on Alcohol and Cancer Risk, released January 3, puts the link between drinking alcohol and developing seven different types of cancer including esophagus, breast, liver and colorectal in the spotlight to help increase awareness. The report calls for adding information about cancer risk to the Surgeon Generals health warning labels on alcohol. And it recommends public health professionals and health care providers discuss the risk, which generally increases the more one drinks, with patients and the public. That way, people can take the risk into account in choosing whether or how much to drink.

NewsHealth & MedicineWhat to know about the first bird flurelated death in the U.S.A Louisiana man who died with H5N1 contracted it from a backyard flock and wild birds A Louisiana man who died with H5N1 bird flu contracted it from exposure to a backyard flock and wild birds, according to state health officials.Bento Orlando/iStock/Getty Images PlusBy McKenzie Prillaman1 hour agoWhile the United States has recorded its first death of a person infected with H5N1 bird flu, public health experts are emphasizing that the risk to most people remains low.The patient, a Louisiana man over the age of 65 who had underlying medical conditions, contracted the virus from a backyard flock and wild birds, the Louisiana Department of Health noted in reporting his death January 6. Further investigation showed no person-to-person transmission of the virus.

Nature, Published online: 02 January 2025; doi:10.1038/d41586-024-04254-9Questions about effectiveness, risks and regulation must be answered before sun-dimming technology can be developed, according to researchers.

Archaeologists working at the site of Saqqara have discovered a 4,100-year-old tomb that held the burial of a doctor.

Rocksteady, the studio behind Suicide Squad: Kill the Justice League, reportedly laid off six more workers at the end of 2024.According to a report from Eurogamer, those who were impacted were part of Rocksteady's programming, art, and quality assurance staff. This apparent round of layoffs follows Rocksteady's first round back in September, which was also reported by Eurogamer, and saw the reduction of 33 team members down to 15 due to the poor sales of Suicide Squad: Kill the Justice League. Rocksteady did not publicly acknowledge either one.Suicide Squad: Kill the Justice League was both a critical and commercial disappointment. Parent company Warner Bros. Discovery said that the game caused a $200 million shortfall. The game also reportedly only has a "barebones" support team as the studio is moving on to new projects.Continue Reading at GameSpot

Grand Theft Auto VI is set for release later this year and it's expected to be among the biggest launches of the year. One analyst has now said the game is so momentous that it could "reshape the gaming industry," similar to how 2013's Grand Theft Auto 5 made a massive mark."While the market landscape has evolved, Rockstar's legacy of delivering groundbreaking experiences ensures that GTA 6 will leave a lasting mark," Newzoo analyst Emmanuel Rosier told GI.biz. Rosier went on to say that GTA 5 benefited from launching into a mature market for PS3 and Xbox 360. GTA 6, meanwhile, is set to launch relatively earlier into the PS5 and Xbox Series X|S lifecycles."Rockstar's history of crafting genre-defining titles positions GTA 6 to set new industry standards. Yet, its challenge lies in navigating a gaming world increasingly dominated by live-service titles. How Rockstar adapts the Grand Theft Auto formula to this evolving landscape will not only determine GTA 6's success but may also redefine the future of open-world gaming," Rosier said.Continue Reading at GameSpot

2025 has begunMicrosoft has announced the first set of additions to Game Pass for 2025, including seven titles lined up for the first half of January.Some of the new additions to Game Pass for January 2025 include the adventure game Road 96 (January 7), followed by EA Sports UFC 5 (January 14), the original Diablo (January 14), and a bunch of games joining the Game Pass Standard catalog. Scroll through the gallery below to see all the new additions.Microsoft adds titles to Game Pass across two waves each month, so check back again later for more Game Pass announcements.In terms of removals, titles like Those Who Remain, Exoprimal, Escape Academy, and Insurgency Sandstorm are leaving Game Pass on January 15. Road 96 Road 96 is available now for Game Pass Ultimate, PC Game Pass, and Game Pass Standard. Lightyear Frontier Lightyear Frontier joins Game Pass Standard on January 8 for Xbox Series X|S. My Time at Sandrock My Time at Sandrock comes to Game Pass Standard on January 7 for console. Robin Hood Sherwood Builders Robin Hood Sherwood Builders comes to Game Pass Standard on January 8 for Xbox Series X|S. Rolling Hills Rolling Hills comes to Game Pass Standard on January 8 for console. EA Sports UFC 5EA Sports UFC 5 comes to Game Pass Ultimate on January 14 for cloud and Xbox Series X|S. Diablo Diablo comes to Game Pass Ultimate and PC Game Pass for PC on January 14.

After more than a decade since the character last appeared in his own game, expectations will likely be high for Level-5's upcoming Professor Layton and the New World of Steam set to release sometime during 2025. Though the titular Professor Hershel Layton has featured in crossovers and spin-offs like Professor Layton vs. Phoenix Wright: Ace Attorney or Layton's Mystery Journey: Katrielle and the Millionaires' Conspiracy, Professor Layton and the New World of Steam will finally see the professor return as the lead in his own game. Moreover, the upcoming game could be hugely significant for the Layton franchise as it reestablishes itself on the Switch.

Some crafting materials in NeiR: Automata are very difficult to come by compared to others. While not directly stated by a color or extra shine, some materials are much rarer and will not be easy to come across, much like the Pristine Screw.