Transient silencing of hypermutation preserves B cell affinity...

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2025-03-19 21:20:08 ·

Transient silencing of hypermutation preserves B cell affinity during clonal bursting

www.nature.com

Nature, Published online: 19 March 2025; doi:10.1038/s41586-025-08687-8B cell germinal centres achieve a balance between clonal expansion and sequence diversification by suppressing somatic hypermutation during proliferative clonal bursts.

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