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WWW.NATURE.COMSaturation genome editing-based clinical classification of <i>BRCA2</i> variantsNature, Published online: 08 January 2025; doi:10.1038/s41586-024-08349-1CRISPRCas9-based saturation genome editing in a humanized mouse embryonic stem cell line was used for comprehensive functional characterization of single nucleotide variants in a region of BRCA2, and shows good agreement with existing variant classifications and high predictive power.0 Commentarios 0 Acciones 154 Views
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WWW.NATURE.COMDaily briefing: Why kids need to take more risks: science reveals the benefits of adventurous playNature, Published online: 08 January 2025; doi:10.1038/d41586-025-00039-wWe learn that lead in the air of ancient Rome might have lowered IQs and discover why children need risky play.0 Commentarios 0 Acciones 157 Views
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Blender Poler bear TankBlender Poler bear Tank 🔥🗿
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WWW.GAMESPOT.COMZelda: Tears Of The Kingdom Switch Handheld Controller Gets Big Discount At Best BuyHori Split Pad Pro - Zelda: Tears of the Kingdom Edition $48 (was $60) See at Best Buy See at Amazon Zelda fans can get the Tears of the Kingdom-themed Hori Split Pad Pro for $48 at Best Buy. The 20% discount from its usual $60 price matches the best price we've seen since the handheld controller launched alongside the game in 2023. Additionally, Best Buy has marked this as a clearance deal, so the retailer will soon no longer carry this specific edition of the Split Pad Pro. Hori Split Pad Pro - Zelda: Tears of the Kingdom Edition $48 (was $60) Hori's Split Pad Pro substantially improves the ergonomics of the Switch in handheld mode by offering more conventional handles, larger buttons, triggers, and joysticks, and a proper D-pad. It also has a pair of remappable back triggers. When Best Buy eventually sells out, the Tears of the Kingdom Split Pad Pro is available at Amazon for $54.Best Buy also has the light gray/yellow Split Pad Compact on clearance for $40 (was $50). The Split Pad Compact is, as it sounds, a smaller version of the Split Pad, but it still improves the Switch's ergonomics. See at Best Buy See at Amazon Continue Reading at GameSpot0 Commentarios 0 Acciones 128 Views
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GAMERANT.COMBest Turn-Based RPGs With Unique Class GameplayTurn-based RPGs are a classic genre that captivates players with the strategy and planning required in each battle. One of the most striking elements of these games is the diversity of classes, each with unique abilities and styles, allowing players to explore different tactical approaches and immerse themselves in dynamic combat full of possibilities.0 Commentarios 0 Acciones 123 Views
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GAMERANT.COMBest Killer Perks In Dead By DaylightThere is a large roster of utterly terrifying Killers in Dead By Daylight. They each have their strengths and abilities that when combined with powerful perks make them brutal killing machines that can make the round a living nightmare for survivors.0 Commentarios 0 Acciones 114 Views
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GAMERANT.COMHow to Beat Ellefale in Ys Memoire: The Oath in FelghanaYs Memoire: The Oath in Felghana may chronologically replace Ys 3, but it is still a great place for new players to dive into the game. This game gives players their first real challenge with Dularn, but Ellefale, The Azure Queen of Death, is in a whole other league. It is also very important to note that players do not want to get anywhere near this boss. Being up close and personal will mean her attacks will connect far more frequently.0 Commentarios 0 Acciones 132 Views
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WWW.TECHRADAR.COMData centers are transforming waste heat into community energy assetsHow data centers are turning their biggest liability - excess heat - into valuable community resources.0 Commentarios 0 Acciones 129 Views