• I started a nonprofit to fight ALS after my husband's death. Here's how tech and AI can help us find a cure.
    www.businessinsider.com
    Indu Navar and her late husband, Peter Cohen. Courtesy of Indu Navar. 2025-03-30T19:58:06Z SaveSaved Read in app This story is available exclusively to Business Insider subscribers. Become an Insider and start reading now.Have an account? Indu Navar has spent her career in tech, building and investing in organizations in Silicon Valley.She founded the Peter Cohen Foundation and EverythingALS after her husband died of ALS.Cohen had a long tech career, too. He built Amazon Mechanical Turk and AWS at Amazon.This is an As-Told-To essay based on a conversation with Indu Navar, the CEO and Founder of EverythingALS. It has been edited for length and clarity.Both my husband and I have been on the ground floor building technology that changed the world.I have degrees in electrical engineering and computer science. I started my career at NASA and was on the founding team of what is today's WebMD. Then, I started another company that I ran for 14 years. After that, I was investing and advising. I've always been fascinated with big data and building analytics on top of it. My husband, Peter Cohen, worked at Amazon for about 18 years. He joined around 1996 or 1997 and built Amazon Mechanical Turk, a crowd-sourcing marketplace.Life was really good. Here we are making change. He was still in his late forties, and then he started saying, "Hey, I think something is wrong with my ankle. It's not dorsal flexing."We're like, "Oh, no big deal, it's just an ankle issue." No, it was a spine issue. Oh no, it was a brain issue. It took us two years to figure out that it was actually ALS, which is degenerative. The method of diagnosing ALS is called elimination, so you eliminate other diseases and problems. I think we spent over $100,000 just to diagnose it.Every 90 minutes, somebody is getting diagnosed with ALS, and they're hearing the same diagnosis they heard 80 years ago. You have 2 to 5 years to live from your first symptom. That's what shocked me. It takes a long time to get diagnosed, and we diagnose late compared to other diseases, like cancer. A lot of people pass away without even being diagnosed.Peter was diagnosed in 2018 and passed away in 2019. It shook us. It shook us in a way that, as entrepreneurs and as problem solvers, we ask how this is in such a dire state where we haven't done something about it in 80 years? This problem is very opaque until you've gone through it.I started a nonprofit in his name called the Peter Cohen Foundation. My goal is to be able to say that he helped cure ALS with what he went through. We used to talk all the time about what we would do differently if we knew this problem existed before it happened to us.Our goal with the Peter Cohen Foundation and EverythingALS is to bring technology innovations to ALS and other neurodegenerative diseases. We do everything from monitoring and assessing what is happening in clinical trials and using sensors to predict what will happen. The sensors measure patients' speech, breathing, walking, and fine motor skills.Today, we don't actually have the tools to figure out if the drug you give a patient is really working because the way they evaluate your deterioration is by asking you, "On a scale of 1 to 4, how is your speech? How is your walking? How easy is it for you to cut your food?" For us, we're vegetarians. We don't cut our food, so how would we know how to answer that? It's called a patient-reported outcome, and a lot of the questioning has not evolved in years.By using sensors, we don't have to wait for you to get to the point where you can't do things. We can actually predict where you're going to be in 3, 6, 9, or 12 months. We'll use them for early diagnosis. We've digitized a lot, and our algorithm is in clinical trials.We call it citizen-driven research because we go directly to patients and do research with people who are being affected by the disease, so we can get thousands of people involved. We send the sensors to them, they wear them, and we monitor them remotely.We have an EverythingALS app that lets patients talk to others who have ALS and have gone through this journey. They can also talk to our LLM-based generative AI tool, but it's not like talking to ChatGPT. Our AI is really walled off and trained only with the data we have and the 220 hours of experts who have spoken to us. It's a very trusted dataset.Right now, we are moving to applying our process to our first other disease, which is Alzheimer's. Huntington's and Parkinson's will be in the near future as well. Our goal is to move the needle and fill the gap. We just felt like there was an unmet need in terms of how we care for people, and if you don't care for people, you'll never come up with a cure.Recommended video
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  • More of Nacelles Excellent Star Trek Toys Are Coming, and We Need Them All
    gizmodo.com
    Were still cackling in delight at the first Nacelle Toys Star Trek drop, which is now available for pre-order after being revealed at last years New York Comic Con. But its time to stop gazing at the Weyoun figure that you still cant believe will soon join your collection, for io9 has an important announcement to make: wave two of Nacelles Star Trek action figure line is coming! At last, Star Trek toys have broken away from their weird history and are now delivering figures on a level that fans have been wanting for literal decades. Revealed at Nacelles Star Trek action figure panel with Nicholas Meyer (director of Star Trek II: The Wrath of Khan and Star Trek VI: The Undiscovered Country) at this weekends WonderCon in Anaheim, CA, the wave two figures kick off with this killer entry: Captain Kirk from Star Trek: Generations This figure was teased at the recent New York Toy Fair, and its the only one with accompanying prototype images so far. Note the accessories: jar of dill weed! HORSE! Nacelle Heres a closer look at the accessories in prototype form: Nacelle Nacelle Nacelle Nacelle Nacelle Nacelle The rest include: Captain Janeway from the Star Trek: Voyager episode Year of Hell Nog (Starfleet Uniform) from Star Trek: Deep Space Nine TPol from Star Trek: Enterprise Valeris from Star Trek VI: The Undiscovered Country Romulan Commander from Star Trek: The Original Series Carol Marcus from Star Trek II: The Wrath of Khan Bem from Star Trek: The Animated Series Worf (Generations Sailor) from Star Trek: Generations Geordi La Forge (Generations Sailor) from Star Trek: Generations Nacelle A press release from Nacelle reminds us that its founder and CEO (not to mention noted toy fanatic) Brian Volk-Weiss specifically wanted these releases to be made by passionate Star Trek fans, for Star Trek fans, and drew on fan feedback and suggestions when deciding which characters to include. Youll note that wave two has 10 figures, building on the eight included in wave one. Were trying to take a simple, but calculated approach with this line, Volk-Weiss added. We want to find the perfect balance of making characters for the first time as toys, combined with doing modern versions of the series main cast in their duty uniforms. By listening to fellow fans, we have hopefully found a line up that will keep everyone excited for many years to come!The attention to detail was impeccable in wave one (those perfectly chosen accessories!), and were eager to see the full images of wave two when theyre made available. As a reminder, heres whos included in wave one: Captain Jellico from Star Trek: The Next Generation episode Chain of Command; Weyoun from Star Trek: Deep Space Nine; Captain Garrett from Star Trek: The Next Generation episode Yesterdays Enterprise; Captain Sulu from Star Trek VI: The Undiscovered Country; Peter Preston from Star Trek II: The Wrath of Khan; Tuvix from Star Trek: Voyager episode Tuvix; Valkris from Star Trek III: The Search for Spock; and Mirror Archer from Star Trek: Enterprise episode In A Mirror, Darkly.For now, you can pre-order wave one at the Nacelle Store. Those initial figures should ship out in October, and cost $29 for individual figures or $225 for the full set. No word yet on when wave two will be up for pre-order or a shipping date, but well keep you posted. Want more io9 news? Check out when to expect the latest Marvel, Star Wars, and Star Trek releases, whats next for the DC Universe on film and TV, and everything you need to know about the future of Doctor Who.
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  • Charles Xavier, Marvels Messiest Asshole, Is Going to Space
    gizmodo.com
    Throughout the history of the X-Men, theres been one constant: Charles Xavier makes everyones lives just absolute hell. Sooner or later, everyone in his circle finds a reason to hate him, and then he goes away to ruin someone elses life until his students and surrogate family need him again. After terrorizing his fellow mutants on Earth the last few years, Charles is doing the next worse thing and spreading his special brand of chaos to the stars. On Friday, Marvel revealed Charles and his frequent lover Lilandra of the Shiar Empire will be major players in the upcoming Imperialcomic. If you havent been keeping up with the X-Men in a while, Charles was imprisoned in his own institute after Krakoa fell and Orchis was defeated. During the recently endedX-Manhuntevent, he broke out and went on the run while suffering from a brain tumor thats been killing innocent people. The various X-Men teams fought individual mutants like Storm and Havok over whether to arrest or help him, but in the end, Xavier meets with Lilandra to jettison off to space and help their daughter Xandra. The big premise ofImperialwritten by Jonathan Hickman and drawn by Iban Coello and Federico Vicentiniis the sudden assassination of several major galactic leaders. So far, Marvels been mum on who specifically gets got, but in addition to being a chaos agent, one thing Charles tends to do is lead. Given Hickmans promise of this event being a huge shakeup for the comics cosmic side, making Xavier a big player in that landscape would certainly fit the bill. But will the various empires of the galaxy survive whatever he puts them through before he dips back to Earth? Well find out more whenImperialkicks off on June 4. Want more io9 news? Check out when to expect the latest Marvel, Star Wars, and Star Trek releases, whats next for the DC Universe on film and TV, and everything you need to know about the future of Doctor Who.
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  • Arch House / Tiago Castro Sousa Lda
    www.archdaily.com
    Arch House / Tiago Castro Sousa LdaSave this picture! Ivo Tavares StudioHousesParedes de Coura, PortugalArchitects: Tiago Castro Sousa LdaManufacturersBrands with products used in this architecture project Manufacturers: BRUMA, Moon on light, Sanitana, Slamp, Stan - FaroMore SpecsLess SpecsSave this picture!Text description provided by the architects. The village house is located at the top of the slope, above the village of Paredes de Coura Due to its location, shape and size, the house is a prominent element that imposes itself on the village experience. It was built for commercial use Pharmacy. Elegant, large spans, decorated with stonework elements, such as jambs, lintels, among others. This house is different from the local architecture. The location, the ornamental elements and the exterior proportions lead us to an image of a spatially refined house. It leads us to imagine spaces decorated with shapes and materials very much in the Art Nouveau style.Save this picture!Save this picture!This imaginary, this dream in which we travel as we pass in front of the house, is not reflected in the interior. The existing interior has monotonous, divided, small and gloomy spaces. It consists of a central space, with high ceilings, facing north and south, but surrounded by four other small spaces to the east and west (bedroom, kitchen, sanitary installation, storage). These are connected directly by interior doors, which multiplies the routes and consequently conditions the habitation of the admittedly central/main space.Save this picture!Save this picture!On the top floor, in the attics, two bedrooms and a storage space. The connection between them is made by a staircase, built between walls and of reduced size. It is clearly an organization that grew out of need. In these, without planning, without concepts, functionalist spaces, the protagonist is the man.Save this picture!Save this picture!Soon the challenge arose! The challenge came from the client, connoisseurs of culture, music and Design, especially lovers of Art Nouveau or arts and Crafts. Both understood that living in the house did not do justice to the object. The project sought to harmonize space and form. It was the challenge of making the imagination come true! Square, simple plan, with large openings on all sides. It sketches a design devoid of sensations.Save this picture!Thus, through natural light, shadow and arch we establish a set of concepts that are reflected in our emblematic imagery. The arch appears in the memory of the use and shapes of the first project. It is an element of pure elegance. Through form, the arch, an element used in history as an element of art, we organize the space and create a new habitation and new sensations.Save this picture!Save this picture!The ground floor, entrance floor, consists of a single space, subdivided by two arcades. This gives rise to 3 spaces for different uses. These elements allowed a single space to provide three interconnected but diverse moments of living Kitchen, Living Room and Dining Room. Clearly these refined elements create an elegant symbiosis between form and function. The upper floor consists of a central office, support room, sanitary installation and storage. On the lower floor, semi-buried, there are two bedrooms, a bathroom and a laundry room.Save this picture!On these floors, for private use, tranquillity reigns through natural northern light. A light, faint, constant, synonymous with serenity. The connection between them is made by a concrete staircase covered in wood. It is a suspended and decorative element, which strictly matches the metrics imposed by the arches. It starts and arrives inside the arches. The arch became the main element of the house. It is the organizing element of the interior space as well as the exceptional element on the exterior (entrance marking). This responds to the dream of Art Nouveau so often spoken in the clients speeches. Arch House.Save this picture!Project gallerySee allShow lessAbout this officePublished on March 30, 2025Cite: "Arch House / Tiago Castro Sousa Lda" [Casa Arco / Tiago Castro Sousa Lda] 30 Mar 2025. ArchDaily. Accessed . <https://www.archdaily.com/1028398/arch-house-tiago-castro-sousa-lda&gt ISSN 0719-8884Save!ArchDaily?You've started following your first account!Did you know?You'll now receive updates based on what you follow! Personalize your stream and start following your favorite authors, offices and users.Go to my stream
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  • Green Screen Effects | 4K 60fps | Chroma Screen Goku VFX Footage for Download
    www.youtube.com
    Green Screen Effects | 4K 60fps | Chroma Screen Goku VFX Footage for DownloadDiscover an impressive collection of Green Screen VFX and Chroma Key Footage in 4K 60fps! This playlist features high-quality VFX assets that are perfect for compositing in your films, videos, and creative projects. With effects from various genres like Fire FX, Smoke FX, and other dynamic elements from Unreal Engine VFX, you can add stunning visual effects to your content effortlessly.Each video includes multiple angles of Chroma Screen footage, allowing you to seamlessly integrate the effects into your scene from different perspectives. These professional-grade assets are optimized for Chroma Key compositing and will save you time on your VFX projects. Key Features:4K 60fps resolution for cinematic-quality visualsMultiple Angles for flexible compositingReady-to-use Fire FX, Smoke FX, and more from Unreal Engine VFXChroma Key (Green Screen) compatible for easy integrationIdeal for filmmakers, video editors, and VFX artistsEnhance your projects with these free downloadable effects and elevate your content. Subscribe for more VFX assets and tutorials!FAB - https://www.fab.com/sellers/CGHOW Whatsapp - https://bit.ly/3LYvxjK Patreon- https://www.patreon.com/Ashif NFT - https://opensea.io/CGHOW Twitter - https://twitter.com/cghow_ If you Liked it - http://bit.ly/2UZmiZ4 Channel Ashif - http://bit.ly/3aYaniw Support me on - paypal.me/9953280644 #cghow #UE5 #UE4Niagara #gamefx #ue5niagara #ue4vfx #niagara #unrealengineniagara #realtimevfxVisit - https://cghow.com/ Unreal Engine Marketplace - https://bit.ly/3aojvAa Artstation Store - https://www.artstation.com/ashif/store Gumroad - https://cghow.gumroad.com/
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  • Unreal Engine 5 Real Time Strategy Game with C++ - Part 21 - Actor Details Panel
    www.youtube.com
    Project Files: https://www.patreon.com/posts/12496746 .This is the 21st part of the tutorial series, where we are going to implement a Real Time Strategy game using Unreal Engine and C++. In this episode, we are going to implement an actor details panel. When we have selected multiple actors, a simple icons that represent all the selected actors along with their health levels/ Hit points. But when we select only one actor, we will see a more detailed representation of the selected actor in the same area of the HUD. Here we will see the selected actor name (farmer, lumberjack, knight.. etc) and a slightly larger icon, hit points, actor properties such as attack and range. We will work on the UI part and how to connect it with existing systems here. Full C++ RTS Playlist: https://www.youtube.com/playlist?list=PLNTm9yU0zou5_PYxEdjNbAgbVRn-daOga .Unreal Strategy game with Blueprints series: https://www.youtube.com/playlist?list=PLNTm9yU0zou4Eulmi8YIfzHiNZEzfbSMk // ! https://www.patreon.com/codelikeme Patrons will have access to project files of all the stuff I do in the channel and other extra benefitsJoin this channel to get access to perks:https://www.youtube.com/channel/UClb6Jh9EBV7a_Nm52Ipll_Q/join Like my facebook page for more content : https://www.facebook.com/gamedevelopersclub/ Follow me on twitter : https://twitter.com/CodeLikeMe2 Follow me on reddit : https://www.reddit.com/user/codelikeme #CodeLikeMe #unrealengine #ue5 #ue4 #indiegamedev
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  • Multiple species of ticks in the US can transmit red meat allergy, CDC reports reveal
    www.livescience.com
    A single bite from one of several tick species can trigger a months-long meat allergy.
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  • Renders of the PSP 3000 that took me too long
    www.reddit.com
    Roughly 60 hrs of work because I work slow. Critiques are welcome :) submitted by /u/Ansterboi [link] [comments]
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  • RT Gleb Alexandrov: Re @samuel_krug lol, I was having similar vibes apparently. "and beyond"
    x.com
    RTGleb AlexandrovRe @samuel_krug lol, I was having similar vibes apparently. "and beyond"
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