Nature, Published online: 08 January 2025; doi:10.1038/s41586-024-08311-1Cryo-electron microscopy of Azotobacter vinelandii FeSIInitrogenase reveals a core complex of molybdenumiron proteins (MoFePs), iron proteins (FePs) and FeSII, in which FeSII mediates interactions with MoFeP and FeP to position their FeS clusters in catalytically inactive but O2-protected states.

Nature, Published online: 08 January 2025; doi:10.1038/s41586-024-08375-zA global multi-taxon extinction risk assessment of freshwater fauna for The IUCN Red List of Threatened Species finds one-quarter of species to be at high risk of extinction.

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The release of Monster Hunter Wilds is just around the corner, but one player has taken the time between sequels to create an even harder way to play an earlier game in the series, Monster Hunter: World. Aaron Callaway decided to beat the game without any weapons by relying only on emotes, including the Hadoken fireball popularized by Street Fighter's Ryu and Ken.Callaway posted a video on YouTube that demonstrated how an emote-only Monster Hunter: World run works. He notes that the other two emotes used were Street Fighter's Shoryuken and Devil May Cry's guns. However, the Shoryuken drained too much stamina and the DmC emote wasn't ideal either. That's why Callaway came to rely on the Hadoken, even though it's also comparatively weak and can only dish out 13 points in damage at most. It's one thing to say you've done something and another to show it. To prove his achievement, Callaway posted his gameplay videos from his emote-only Monster Hunter: World run. The first video alone is just under three hours, but these videos demonstrate that the challenge is possible, even though there's no Achievement or Trophy waiting at the end for sticking with it.Continue Reading at GameSpot

One of Konami's next big games is Metal Gear Solid Delta: Snake Eater, a remake of the 2004 game. With the calendar now changed over to 2025, that means 2024 came and went entirely without Konami giving any major update on the game or telling fans when they can expect to play it.Metal Gear Solid Delta: Snake Eater was announced at the PlayStation Showcase in 2023, but at the time, Konami did not provide a release date, or even a window, for the game. It was never confirmed for a 2024 release, either, but fans thought it might release during the year due in part to an erroneous social media post. It didn't, so the wait continues. At the end of October 2024, a financial document from Konami listed the release date for Metal Gear Solid Delta: Snake Eater as "TBD." A spokesperson for Konami told GameSpot, "Right now there's nothing new we can share at the moment."Continue Reading at GameSpot

World of Warcraft continues to pay tribute to Mats "Ibelin" Steen, the subject of the recent Netflix documentary The Remarkable Life of Ibelin, this time transforming Steen's character into a full-fledged NPC.As spotted by Wowhead, dataminers have discovered an NPC by the name of Lord Ibelin Redmoore on the public test realm for the MMORPG's upcoming 11.1 update. The NPC's appearance matches Ibelin's look in the documentary, though it's currently unclear where players will be able to find Ibelin in-game or what he might have to say should players interact with him.Steen suffered from Duchenne muscular dystrophy and played WoW as a means of socializing and connecting with others. His character Ibelin, who he often roleplayed as, labeled himself as a private investigator and would use his in-game job title as a means to strike up conversation.Continue Reading at GameSpot

Anime has its distinct feel, and if theres anything that makes anime more special, it has to be music. Starting with action-packed intro songs to sad insert songs that play at the end of the episodes, anime songs are not just any song or there to just fill in the rest of the time until the episode reaches its running timeanime songs are a feeling. Theyre the catchy songs you sing to while taking a shower or the songs you crank up when you feel dramatic about doing your laundry. But in point, these less-than-two-minute tracks are highly valuable in defining the anime's whole plot and, contrary to popular belief, its success.

To prepare players for the hellish grind that is the endgame of Path of Exile 2, the developers have left easy-to-miss encounters in the main campaign that provide permanent buffs, additional passive skill points, and weapon set skill points to characters.

There are only a handful of customizable weapons in Metro Exodus. However, each weapon can be set up with hundreds of different attachment combinations and upgrades. This means that there are dozens of viable setups for each gun in-game. When attempting to rank the best weapons in the game, there are a few things to keep in mind.

Critical Role, the ongoing Dungeons & Dragons campaign played by a group of popular voice actors, is on pause until next week due to the ongoing, devastating wildfires in Los Angeles. The group announced the delay on its social media on Wednesday: As the evolving fires in Los Angeles are directly impacting our cast and crew, were taking a break from streaming this week with the intention of returning to Exandria next Thursday, January 16th. The Critical Role series is typically broadcast on Twitch and YouTube on Thursdays. It stars voice actors including Matthew Mercer, Ashley Johnson, Laura Bailey, Travis Willingham, Marisha Ray, Sam Riegel, Taliesin Jaffe, Liam OBrien, and more many of whom are located in Los Angeles alongside production staff and support crew.IMPORTANT UPDATE As the evolving fires in Los Angeles are directly impacting our cast and crew, we're taking a break from streaming this week with the intention of returning to Exandria next Thursday, January 16th. Critical Role (@criticalrole.bsky.social) 2025-01-08T22:32:20.700ZAs of this exact moment, the two largest fires burning throughout the Los Angeles area are 0% contained, Critical Role senior vice president of marketing Rachel Romero told Polygon in a statement. I heard on the local news this morning that the fire thats burning in the Palisades is the most destructive fire in Los Angeless history. Some of our family, friends, colleagues, co-workers have lost their houses, businesses, and other places that feel like home to them. We are absolutely heartbroken to see so much destruction and loss in our own backyard and encourage everyone to take a moment and think through how they can best support whether that is through a monetary donation, food or supplies donations here locally, or just sharing resources within your own network, whether it be online or offline.Critical Role Foundation has donated $30,000 to the California Community Foundations Wildlife Recovery Fund, according to a post on BlueSky. This is largely in part due to the Critical Role Foundation, an organization that accepts donations from the passionate Critical Role fan community.We are inexplicably grateful to the Critical Role community, who has allowed us the opportunity to create meaningful change through the Critical Role Foundation, said Romero, who is a board member for the Critical Role Foundation. CRF allocates 10% of every donation to an emergency fund, which allows us to be able to send aid quickly in the event that something tragic like this unfolds. We are keeping our community in Los Angeles, as well as all of the incredible people working to put the fires out (and the support staff around them!), in our hearts.Five major fires are currently burning in Los Angeles Country, the largest of which is the Pacific Palisades fire, which has spread to 17,000 acres as of Thursday morning. More than 100,000 people have been forced to evacuate while heavy winds pushed the fire erratically around the city and its surrounding areas. Five people have died due to the fires, and thousands of buildings including schools, homes, and businesses have been damaged or destroyed. Combined with the Palisades fire, the Eaton fire, Hurst fire, Lidia fire, and Sunset fire account for 28,896 acres burned.California residents and others aresharing resources to help their communities; Planet Fitness gyms in Los Angeles Country are open to non-members, and others are handing out quality masks to protect residents from dangerous wildfire smoke. There are tons of regional and grassroots organizations accepting donations,including the LAFD Wildfire Emergency Fund,Mutual Aid LA,Our Big Kitchen, and more.Correction: This story has been updated to correct the spelling of Sam Riegels name, as well as to clarify and include further details about CRFs donations.