Nature, Published online: 05 March 2025; doi:10.1038/s41586-025-08683-yComputational drug discovery is used to identify a 12-mer peptide derived from BRINP2 with potent anti-obesity effects that are independent of leptin, glucagon-like peptide 1 receptor and melanocortin 4 receptor.

Nature, Published online: 05 March 2025; doi:10.1038/s41586-025-08610-1Construction of a phosphate passivation layer on the surface of a cathode to withstand fluctuating operation in alkaline seawater is proposed following understanding the mechanism behind the dynamic evolution and degradation of cathode in intermittent electrolysis.

submitted by /u/damnboychill [link] [comments]

.@t_looman explored Quixel's new Dark Ruins sample project, spending an hour optimizing it in Unreal Engine 5.5 while sharing valuable tips and tricks on lighting, VSMs, Nanite, Niagara, and more.Watch here: https://80.lv/articles/optimizing-quixel-s-new-dark-ruins-environment-in-unreal-engine-5/

Spilled! is a cozy pixelated game where you clean up ocean waste and pollution. It is created by @LenteGameDev, an indie developer living on a real boat.It will be released in three weeks. Wishlist: https://80.lv/articles/this-cozy-eco-conscious-game-by-an-indie-dev-living-on-an-actual-boat-is-coming-soon/

Want to create hyper-realistic 3D renders? Join us in the latest Studio Sessions tutorial series as Aleksandr Eskin walks through his workflow making a photorealistic dropper using Houdini & Octane. Watch now: https://nvda.ws/43o2O18

Putting the max in maximum performance RS MAX offers the best static pressure performance in our fan lineup. Explorer has the full breakdown of this powerhouse of a fan: https://cor.sr/Explorer-RS-Max

Connect how you want with the K70 CORE TKL WIRELESS Slipstream Wireless v1.5 Bluetooth Wired via detachable USB-C

Discord has become a popular messaging platform in recent years, and it undoubtedly provides a convenient channel between developers and players, no matter which platform they use, PC, PlayStation, or Xbox. Now, its reported that the company is preparing for an initial public offering.According to different sources of The New York Times, in recent weeks, the company has been in early talks with bankers regarding preparations for an IPO as soon as this year. However, this is said to be exploratory and may be subject to change.We understand there is a lot of interest around Discords future plans, but we do not comment on rumors or speculation. Our focus remains on delivering the best possible experience for our users and building a strong, sustainable business, commented a spokesperson from Discord.This is not the first time that the public has heard about the companys attempt to go public or change owners. Back in 2021, there were circulating discussions that three buyers, including Microsoft,had shown interest in acquiring the chat app. In the end, the company decided to stand independent for a while and halt any sales talks.During the past four years, Discord has enjoyed greater popularity and one of the reasons is that it is free to use while also offering advanced features for paid users. As a business company, it has been trying to increase its revenue, and its effort saw fruition as its revenue in 2023 had risen to $600 million. Last year, it introduced the sponsored ads function, which was regarded as a negative sign by the community to prioritize earnings over user experiences.With the latest IPO news, gamers, who comprise the majority of the platforms users, which is up to 90%, have expressed their concerns over more ads and monetization features.Join our80 Level Talent platformand ournew Discord server, follow us onInstagram,Twitter,LinkedIn,Telegram,TikTok, andThreads,where we share breakdowns, the latest news, awesome artworks, and more.Source link The post Discord Is Reportedly In Talks About Public Listing appeared first on CG SHARES.

Bethesda has announced that Starfield will receive significant updates throughout 2025, sharing the news in a recent social media post.In a recent Twitter post on the games official account, the devs shared that they have been working on the sci-fi RPG. While details remain scarce, the developers assured fans that they are actively working on the game and have exciting plans in store. Bethesda promises a lot of exciting things already in 2025: The team has been hard at work, and while were not ready to share specific details just yet, we have a lot of exciting things planned for the game this year that we cant wait to talk about when the time is right.BethesdaThis update comes after a period of relative silence regarding new content for Starfield.The latest update on the space RPG was announced in November, and recently, we havent had any news on any new DLCs. Shattered Space, released last autumn, received very mixed reviews. The DLC, focusing on the story of VaRuun culture, features a hand-crafted world, which is differenr from the base games procedural content.Recently, beyond DLC discussions, intriguing details about Starfields development also emerged.A former Senior Character Artist on Skyrim, Fallout 4, 76, and Starfield, Dennis Mejillones, shared that Starfield could have had a gore system.While the developers remained tight-lipped about the details of the new game content, as 2025 progresses, fans seemingly can expect more information about the space game.Dont forget to join our 80 Level Talent platform and our new Discord server, follow us on Instagram, Twitter, LinkedIn, Telegram, TikTok, and Threads, where we share breakdowns, the latest news, awesome artworks, and more.Source link The post Bethesda Announces A Lot of Exciting Things for Starfield This Year appeared first on CG SHARES.