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Drug negotiations Maker of weight-loss drugs to ask Trump to pause price negotiations: Report The next 15 drugs up for negotiation will be released soon and may include a GLP-1. Beth Mole Jan 14, 2025 5:26 pm | 35 An Eli Lilly & Co. Zepbound injection pen arranged in Brooklyn, New York on March 28, 2024. Credit: Getty | helby Knowles An Eli Lilly & Co. Zepbound injection pen arranged in Brooklyn, New York on March 28, 2024. Credit: Getty | helby Knowles Story textSizeSmallStandardLargeWidth *StandardWideLinksStandardOrange* Subscribers only Learn moreEli Lilly and other drugmakers are reportedly planning to urge the Trump administration to pause Medicare drug-price negotiations that were put in place by the Biden administration's Inflation Reduction Act (IRA)."They need to fix [the IRA]," Eli Lilly CEO Dave Ricks told Bloomberg at the JPMorgan Healthcare Conference in San Francisco.The results of the first round of IRA negotiations, announced in August, saw the list prices of 10 high-cost drugs get slashed by as much as 79 percent. Collectively, the negotiated prices are estimated to save seniors $1.5 billion in out-of-pocket costs in 2026, when the prices go into effect. The savings will likely be well received, given that KFF polling has found that over a quarter of Americans struggle to afford prescription medications, and 31 percent say they haven't taken medicines as prescribed due to costs.Nevertheless, drugmakers have made no secret that they loathe negotiating lower prices. The pharmaceutical industry has filed several lawsuits, claiming the negotiations are unconstitutional. So far, the legal fights have been unsuccessful.Now, the next list of 15 drugs up for negotiation is scheduled to be released by February 1, and experts have speculated that the Biden administration may release them before the Trump administration comes into office on January 20. Moreover, the list of 15 is expected to include the blockbuster drug semaglutide, the GLP-1 class drug behind the brand name weight-loss and diabetes drugs Wegovy and Ozempic, made by Novo Nordisk. That would be bad news for Lilly, which makes competing GLP-1 drugs Zepbound and Mounjaro.Popular prescriptionsFor now, Medicare does not cover drugs prescribed specifically for weight loss, but it will cover GLP-1 class drugs if they're prescribed for other conditions, such as Type 2 diabetes. Wegovy, for example, is covered if it is prescribed to reduce the risk of heart attack and stroke in adults with either obesity or overweight. But, in November, the Biden administration proposed reinterpreting Medicare prescription-coverage rules to allow for coverage of "anti-obesity medications."Such a move is reportedly part of the argument Lilly's CEO plans to bring to the Trump administration. Rather than using drug price negotiations to reduce health care costs, Ricks aims to play up the potential to reduce long-term health care costs by improving people's overall health with coverage of GLP-1 drugs now. This argument would presumably be targeted at Mehmet Oz, the TV presenter and heart surgeon Trump has tapped to run the Centers for Medicare and Medicaid Services."My argument to Mehmet Oz is that if you want to protect Medicare costs in 10 years, have [the Affordable Care Act] and Medicare plans list these drugs now," Ricks said to Bloomberg. "We know so much about how much cost savings there will be downstream in heart disease and other conditions."An October report from the Congressional Budget Office strongly disputed that claim, however. The CBO estimated that the direct cost of Medicare coverage for anti-obesity drugs between 2026 and 2034 would be nearly $39 billion, while the savings from improved health would total just a little over $3 billion, for a net cost to US taxpayers of about $35.5 billion.Beth MoleSenior Health ReporterBeth MoleSenior Health Reporter Beth is Ars Technicas Senior Health Reporter. Beth has a Ph.D. in microbiology from the University of North Carolina at Chapel Hill and attended the Science Communication program at the University of California, Santa Cruz. She specializes in covering infectious diseases, public health, and microbes. 35 Comments

Finland said a Russia-linked oil tanker was close to wreaking havoc on its undersea cables.Its president said that officials intervened about 12 minutes before the damage got "much worse."The tanker is accused of being part of a Russian "shadow fleet" sabotaging European infrastructure.Finnish President Alexander Stubb said on Tuesday that his country had stopped the crew of a Russia-linked oil tanker just minutes before it caused catastrophic damage to undersea cables in the Baltic Sea."Had it continued for another 12 minutes, the carnage would have been much worse than the four basic cables that were there," Stubb told reporters at this week's Baltic-focused NATO summit in Helsinki.The tanker, the Eagle S, was seized in late December as Finland probed recent damage to its Estlink-2 power line, one of two vital cables carrying electricity in the Baltic Sea.Four data cables were also severed.Finnish investigators have accused the Eagle S crew of trying to sabotage the cables by dragging the ship's anchor for miles along the seabed.The Finnish head of the investigation, Risto Lohi, told Reuters on Tuesday that the Eagle S would likely also have attempted sabotage on the other power cable, the Estlink-1, had police not boarded the vessel."There would have been an almost immediate danger that other cables or pipes related to our critical underwater infrastructure could have been damaged," said Lohi, who is the chief of Finland's National Bureau of Investigation.On Tuesday, Stubb said that Finland's security process for protecting the cables started with the private company overseeing them. If a cable is severed, the firm would alert the authorities, who then try to find possible ships around the location of the damage."Once that happens, you identify the ship and contact the ship. Number four, you stop the ship," Stubb said.Stubb added that Finnish authorities would compel the ship to enter Finnish waters, where officers could then legally board the vessel.That process is set to change now. European members of NATO announced at the summit that they would launch a new program, called the "Baltic Sentry," to collectively patrol near Baltic Sea infrastructure.The surveillance program involves frigates, maritime aircraft, and "a small fleet of naval drones," said NATO's secretary-general, Mark Rutte, at the summit.The investigation into the Eagle S is of particular significance to the European Union because it's suspected for years that Russia has been intentionally trying tocovertly damage Western undersea infrastructure.Other cables, such as two fiber-optic data cables running between Finland and Germany, were cut last year.Though the Eagle S is registered in the Cook Islands, European officials say it's tied to Russia because it was carrying 35,000 tons of unleaded gasoline loaded in Russian ports.They have accused the ship of being part of a Russian "shadow fleet," or a network of vessels with owners registered outside Russia that are actually carrying sanctioned Russian oil.Russia has denied being involved in any way with such sabotage. The Russian Foreign Ministry did not respond to a comment request sent outside regular business hours by Business Insider.

By AJ Dellinger Published January 14, 2025 | Comments (6) | A person wearing a Razer Zephyr mask while typing on a laptop next to a person wearing a standard mask Razer If you let your gamer brain win and bought an N95 mask from Razer, a company best known for its keyboards and computer mice, then you may be entitled to compensationwell, at least a refund. The Federal Trade Commission announced Monday that it reached a settlement with the gaming hardware company that will set aside $1 million to reimburse people who purchased the Razer Zephyr, a short-lived N95 mask sold by the company during the COVID-19 pandemic. Under the terms of the agreement, the FTC said it would send checks and PayPal payments containing full refunds to 6,764 consumers who purchased the mask. According to the agency, consumers who bought a Zephyr will have 90 days to cash their check once received or 30 days to accept their PayPal payment. The FTC will be sending out the payments based on records received from Razer and does not require consumers to file a claim. The payout represents the end of a surprisingly thorough saga that saw the FTC crackdown on Razer for falsely marketing its Zephyr masks. The company first started offering the masks in 2021, claiming the product was FDA-registered and lab-tested for 99 percent BFE [Bacteria Filtration Efficiency] and offered greater protection compared to standard disposable/cloth masks thanks to its replaceable N95 grade filters for maximum protection. Turns out, not so much. According to the FTCs investigation, Razer never submitted the Zephyr masks to the FDA or the National Institute for Occupational Safety and Health for testing, and they were never certified as N95 grade. Instead, the company conducted tests through a third-party contractor, but even those results showed the masks fell short. To qualify as N95 grade, the mask must achieve 95% or greater particulate filtration efficiency. The third-party tests saw the Zephyr max out at 86.3% in an area with fans on, and frequently tested much lower.Despite knowing this, Razer decided to market the mask as N95 anyway, which is a pretty major no-no. The company sold the masks for a few months spanning the back half of 2021 and the start of 2022, charging $100 a pop before pulling the product as it started to receive scrutiny.While the company did inform buyers after the fact that the Zephyr was not a medical device nor certified as an N95 mask, it did not inform those buyers that refunds were available. As a result, the FTC found less than 6% of Zephyr purchases got their money backwhich it is setting out to rectify with this settlement. Better late than never.Daily NewsletterYou May Also Like By Kyle Barr Published January 7, 2025 Renee Dudley Published December 28, 2024 By AJ Dellinger Published December 17, 2024 By Todd Feathers Published December 12, 2024 By Matt Novak Published December 12, 2024 By Matt Novak Published December 4, 2024

Peckish Bakery / guudpin designSave this picture! wgh_photoArchitects: guudpin designAreaArea of this architecture projectArea:123 mYearCompletion year of this architecture project Year: 2024 PhotographsPhotographs:wgh_photo Lead Architects: Pin Yun Chiu More SpecsLess SpecsSave this picture!Blending Neighborhood Culture and Urban Scenery: A Fusion of Old and New Culinary Experiences Peckish, the new bakery and dining brand under Ivette Cafe, continues its mission of promoting culinary culture by bringing a fresh, humanistic experience into the community. Situated in the context of the Minsheng neighborhood, the building's original faade has been preserved, resonating with its mosaic-patterned arched exterior. Using everyday materials such as cement and red bricks, the space narrates a timeless story. The interplay of steps and walls creates a dynamic layered faade that seamlessly integrates into the local atmosphere.Save this picture!The interior walls are painted in bright tones to offset the oppressive feel of the low-ceilinged storefront typical of old apartments. The layout has been reimagined, with the original floor plan dictating the spatial arrangement. Functional areassuch as the service zone, seating area, and curated product sectionare thoughtfully allocated, reflecting the interactions of the surrounding neighborhood. As visitors step into the space, they are guided to explore, connect, and ultimately leave with a fresh and meaningful experience.Save this picture!Save this picture!The original beams and columns symbolize the essence of the old, contrasting with the fresh woodwork and wooden furniture that embody the new. Indoor greenery echoes the lush view through large windows, creating a harmonious dialogue. The central island-style bar, featuring playful orange tiles and rectangular blocks interwoven with tiered shelving, adds a dynamic visual appeal. Here, guests can enjoy their meals while experiencing the vivid rhythm of everyday life that integrates seamlessly with the locale.Save this picture!Save this picture!Save this picture!In line with its brand identity, the interior prominently features Ivette Cafe's signature green and Peckish's distinctive orange-pink hues. These colors are applied to custom-made furniture, tiles, and product shelves, establishing a striking visual character. Extending the brand's artistic spirit, the space showcases four collectible pieces by Rotganzen from the Netherlands. Special lighting enhances the reflective surfaces of these works, casting shimmering silver patterns on the walls and enriching the sensory experience.Save this picture!Save this picture!As the third store in the brand's expansion, the concept of "three" is subtly embedded in the designseen in door handles, triangular chairs, chair legs, and the arrangement of art pieces. Reflecting on what already exists and envisioning what can be brought forth, the interplay between the old and new, arrival and departure, sparks joyful interactions within the space.Save this picture!Project gallerySee allShow lessProject locationAddress:Taipei, TaiwanLocation to be used only as a reference. It could indicate city/country but not exact address.About this officeguudpin designOfficePublished on January 15, 2025Cite: "Peckish Bakery / guudpin design" 15 Jan 2025. ArchDaily. Accessed . <https://www.archdaily.com/1025720/peckish-bakery-guudpin-design&gt ISSN 0719-8884Save!ArchDaily?You've started following your first account!Did you know?You'll now receive updates based on what you follow! Personalize your stream and start following your favorite authors, offices and users.Go to my stream

Nature, Published online: 14 January 2025; doi:10.1038/d41586-025-00112-4Philanthropic foundations must step in to shield science from Trumps cuts

Here are some of her studies submitted by /u/ArtsyAttacker [link] [comments]

Dynasty Warriors: Origins Physical Edition $70 | Free $10 gift card with Best Buy preorder Preorder at Best Buy Preorder at Amazon Preorder at Walmart Dynasty Warriors: Origins Digital Deluxe Edition $73.79 for PC (was $90) | Available Now See at Fanatical Following a lengthy hiatus, the mainline Dynasty Warriors franchise is back this Friday, January 17, with the most ambitious entry in the hack-and-slash action series to date. Dynasty Warriors: Origins has some enticing launch and preorder offers that fans will want to check out before they expire.Dynasty Warriors: Origins' Digital Deluxe Edition is actually already available, as one of the perks of the $90 Digital Deluxe Edition is three-day early access. This version costs $90, but PC players can purchase a Steam key from Fanatical for $73.79 right now. If you want a physical edition for console, Best Buy is giving away $10 digital gift cards with preorders for PS5 and Xbox Series X. This offer isn't available for the digital edition, but PC players can save over $12 on Steam preorders of the standard edition at Fanatical.Continue Reading at GameSpot

Even with dynamic RGB effects, many mechanical keyboards seem all too familiar. The Logitech G713 breathes fresh air into stale setups with its bright exterior and whimsical cloud-shaped palm rest.