Nature, Published online: 15 January 2025; doi:10.1038/s41586-024-08423-8Persistent DNA lesions can occur throughout the human lifespan and can remain in the genome of affected cells for several years and generate a substantial proportion of the mutational burden.

Twenty years ago, the Huygens probe achieved humanity's first landing on a moon in the outer solar system when it touched down on Titan.

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The Decades Challenge is a popular legacy challenge where players guide their Sims through the eras, starting in the 1890s and advancing decade by decade while adapting to the changing historical norms, technology, and lifestyles of the times. This unique The Sims 4 challenge emphasizes creativity, storytelling, and historical accuracy, requiring players to mimic real-world events and societal shifts.

I'm planning on starting my own studio soon. Is there anyone who can be a mentor to me or give me any tips on how to start a game studio. Please and thank you

Season 7 of Diablo 4, formally called the Season of Witchcraft, goes live this week a welcome injection of hells heat to offset winters cold embrace.Season 7 is the first season to follow last years release of the Vessel of Hatred expansion, giving players something new to focus on now their DLC campaigns have long wrapped.Heres when Diablo 4 season 7 releases in your time zone, plus a little bit about what to expect when the season goes live.Diablo 4 season 7 release time in your time zoneDiablo 4 season 7 begins on Tuesday, Jan. 21, at 1 p.m. EST. Heres the release time in your time zone:10 a.m. PSTfor the West Coast of North America1 p.m. ESTfor the East Coast of North America6 p.m. GMTfor the U.K.7 a.m. CETfor Western Europe/Paris3 a.m. JSTon Jan. 22for TokyoWhile these are the expected release times for Diablo 4s latest season, theres always the chance technical difficulties could impact the rollout. Well update this post once the season is live or if Blizzard announces any changes to the schedule.What to expect from Diablo 4 season 7The top-line mechanic for Diablo 4 season 7 is the introduction of witchcraft powers. Via the seasonal questline, you can acquire magical abilities across three skill trees: offensive Eldritch magic, defensive Psyche magic, and offensive/defensive Growth and Decay magic. All good skills to master against the new Headrotten enemy type.There are also a handful of welcome changes to loot and gear. The Armory feature will allow you to save up to five loadouts per character. Diablo 4 season 7 will additionally add eight new Uniques and eight new Legendary Affixes. And if you own the Vessel of Hatred expansion, youll have access to three new Runes.You can read a detailed breakdown of every minute Diablo 4 season 7 change over at the Blizzard blog.

In well over a decade of journalism, I've seen a fair amount of copied designs, but I've never seen anything as blatant as Bing's recently abandoned attempt to hoodwink people into believing they were actually using Google. Since time immemorial, people have used a system's default apps to look for better alternatives, and to switch to those instead. Back in the day, Internet Explorer was often used to download Firefox or Chrome, before being forgotten forever. Now, the same thing is happening with BingMicrosoft's search engineand the company clearly isn't pleased about it.If you use Microsoft's Edge browser and haven't changed any of its default settings, Bing is your search engine. Earlier this month, when you typed the word "Google" into that browser's address bar, you would see a page that you may have mistaken for a Google search, but you'd actually still be on Bing. The illusion came complete with a fake Google doodle, a search bar with Google-like text underneath it, results laid out in a way that aped Google's design, and other spoofed Google UI elements. This was first spotted by 9to5Google.The worst part was that the spoofed page even hid Microsoft Bing's branding by automatically scrolling past it. Normally, Bing's branding and the search bar are prominently visible at the top of every search.A few weeks later (and after the practice garnered a whole lot of attention, from this website and others), the charade seems to be over: Searching for "Google" on Bing now takes you to a standard Bing results page. But it's clear that they attempted this scheme at all that Microsoft has noticed that people are using Bing to locate Google, and isn't happy about that. Parisa Tabriz, the vice president of Google Chrome, expressed her displeasure at the move on X (formerly Twitter). Her post reads, "Imitation is the sincerest form of flattery, but Microsoft spoofing the Google homepage is another tactic in its long history of tricks to confuse users & limit choice. New year; new low @Microsoft." If you're unhappy with such tricks, you can easily switch the default browser on Windows 11.Editor's note: We have reached out to Microsoft for comment but haven't yet gotten a response.

It hasn't even been a full day since ByteDance shut down TikTok in the US, and now it says it's coming back. In a statement posted on X Sunday afternoon, TikTok wrote, "In agreement with our service providers, TikTok is in the process of restoring service."STATEMENT FROM TIKTOK:In agreement with our service providers, TikTok is in the process of restoring service. We thank President Trump for providing the necessary clarity and assurance to our service providers that they will face no penalties providing TikTok to over 170 TikTok Policy (@TikTokPolicy) January 19, 2025 Developing...This article originally appeared on Engadget at https://www.engadget.com/social-media/tiktok-says-its-restoring-service-in-the-us-175440013.html?src=rss

Many firms remain unconcerned about AI energy usage, for now.

TikTok was available to some U.S. users on Sunday after President-elect Donald Trump said that he would sign an executive order to delay a federal ban.