Nature, Published online: 22 January 2025; doi:10.1038/d41586-025-00228-7The chance of a lucky break in biomedical research increases with bigger funding grants. Plus, the changing landscape of menopause treatments.

Nature, Published online: 22 January 2025; doi:10.1038/s41586-024-08455-0A massively parallel assay developed to map the essential photosynthetic enzyme rubisco showed that non-trivial biochemical changes and improvements in CO2 affinity are possible, signposting further enzyme engineering efforts to increase crop yields.

In this video, youll learn how to use Cinema 4Ds PolyFX to break your object into small pieces that gradually come together for a reveal. This feature has been around for a while and is pretty handy for motion graphics and similar projects, perfect for creating sci-fi and technology animations.Another key aspect of this tutorial is demonstrating how to use a proxy object to apply the animation first, which lets you fine-tune everything quickly before applying the effects to your high-resolution object. Grab the free car model used in the tutorial here and follow along.The Pixel Lab is a fantastic resource for 3D and VFX Artists, offering a huge collection of free models, hundreds of tutorials for Cinema 4D, Octane, and After Effects, and other great products designed to speed up your motion design workflow. Check out some of their recent quick tips and visit their site for more:Also,dont forget to join our80 Level Talent platformand ournew Discord server, follow us onInstagram,Twitter,LinkedIn,Telegram,TikTok, andThreads, where we share breakdowns, the latest news, awesome artworks, and more.Source link The post Tutorial: Creating Transition & Reveal Effect In Cinema 4D appeared first on CG SHARES.

An artist known as tetra decided to test the range of motion of Live2D and 3D models, showing a cute anime girl making faces. Spoiler: there isnt that much difference, although the 3D one looks a little freer with its movement.If youre not familiar with it, Live2D is an animation technique used to animate images by separating them into parts and working on each. It is also software that generates real-time 2D animations based on this.One of the best illustrations for this is rukusu20XXs experiment with a 3D body and a Live2D head:We have also recently seen a 3D-like halo made in Live2D, a hand model, a cute cat, and a smooth anime character.If you like tetras work, visit their X/Twitter for more.Also, join our80 Level Talent platformand ournew Discord server, follow us onInstagram,Twitter,LinkedIn,Telegram,TikTok, andThreads,where we share breakdowns, the latest news, awesome artworks, and more.Source link The post Artist Compared Range of Motion of Live2D & 3D Models appeared first on CG SHARES.

David Lynch was one of the most revered filmmakers in Hollywood, with classics such as The Straight Story, Twin Peaks, Eraserhead, and Mulholland Drive credited to his name throughout his nearly 50-year career writing and directing for film and TV. Lynch also directed the first adaptation of Frank Herbert's sci-fi novel Dune. Unlike Twin Peaks and the aforementioned films, Dune was not well-received in 1984--Lynch himself wasn't even a fan--but audiences have warmed up to it over the years. If you're interested in revisiting Lynch's work or experience it for the first time in the wake of his death last week, Dune remains fascinating and visually impressive 40 years after its release.David Lynch's Dune: Special Edition (4K Blu-ray) is on sale for only $25, down from $50, at Walmart. Amazon had this deal earlier today but was sold out at the time of writing. And if you'd like to learn more about the tumultuous production of one of Lynch's most divisive films, the 560-page oral history of Dune is available for only $20 in hardcover format at Amazon and Walmart. Continue Reading at GameSpot

SNK fans have been anticipating the April 24 launch of Fatal Fury: City Of The Wolves for some time, but they won't have to wait much longer to get a brief taste of the action. SNK has announced an open beta test for February 20-24, and all platforms will be included for the duration.Eight characters will feature in the open beta, though the list has not yet been revealed. The test will feature three different online modes--Ranked Match, Casual Match, and Room Match--as well as an offline Training mode for players to learn the moveset of each available character.The Fatal Fury beta test is set for February 20-24. See at Best Buy The test specifically begins February 20 at 12 AM PST, and it will run until February 24 at 11:59 PM PST. SNK has also confirmed that participation in the test will not require a PlayStation Plus or Xbox Game Pass subscription on their respective platforms, so anyone who wishes to try the beta out can download and play.Continue Reading at GameSpot

To complete the challenge, players must collect at least 75% of the book's pages. However, collecting 95% of the pages for each challenge unlocks an achievement called Freehand Circle, making it worthwhile for players aiming to complete every achievement. Heres how to complete these puzzles in general in Wuthering Waves.

For over three decades, The Legend of Zelda has remained an integral part of gaming history, being many peoples first high-fantasy adventure experience. The original game on the NES was revolutionary, which led to it being a success and the start of a flagship Nintendo franchise.

Earlier this week, individuals within the tabletop ecosystem began noticing that the Ennies one of the most prestigious awards in the industry, which have been held at Gen Con for over two decades allowed potential nominees to indicate whether their submissions include content generated with artificial intelligence. With continued controversy surrounding the use of generative AI in tabletop games, due to the technologys environmental impacts, its basis in exploitative labor from workers in the global south, and its foundations built on content largely scraped from artists without their consent, the revelation prompted a swift backlash on social media against the awards ceremony, which had already faced an earlier round of criticism for a lack of professionals of color in its judging pool.The AI Content Certification option on the submission form states that the awards show accepts products that include AI generated content, provided that the potential nominee discloses which part of their project is AI-generated. However, any element of the work that includes AI-generated content wouldnt be able to receive an award in that category. The example provided in the disclaimer states that a project with a human-made cover but artificially generated interior art would theoretically be eligible to win Best Cover Art but not Best Interior Art.The statement then goes on to say that this disclosure is largely on the Honor System, as the judges or submissions coordinator will not feasibly be able to identify which submissions are AI-generated with 100% accuracy, just as [they] currently cant identify potential copyright violations, or re-use of art from other products. Submissions that are found to be using AI after the fact will be delisted, and any awards revoked, with the creators in question to be potentially prohibited from submitting future products.An Ennie Awards spokesperson told Polygon that the award committee was working on a full response to public concerns. They also noted that this is the second year the policy has been in effect, and that the committee had received no feedback from the 900+ submissions that were required to check the box last year. With more attention given to the subject of AI-generated content in the wake of its use by Hasbro, members of the industry are perhaps more aware of the technology now than in previous years. The spokesperson went on to state that only 0.05% of submissions disclosed using AI content, with the majority of those submissions being for Online Content/Digital Media.The Ennies representative said that the awards committee will not change its eligibility requirements mid-year (as the deadline for submissions is March 31), noting that judges will have full access to this information and can take it into consideration as they review products. However, they stated that as the Ennies are and always have been a community award, the ENNIE Staff is currently considering putting the choice to a vote on the eligibility of AI content as part of this years awards ballot. The Ennies are fan-curated and fan-selected by a panel of volunteers.

You may recognize Taki Udon from his retro gaming YouTube channel, but last year he started a company to manufacture gaming hardware, including a much-cheaper variant of the DE10 board behind the popular open-source MiSTer FPGA project you can read all about my beloved MiSTer here and he hasnt slowed down since.After a series of teases, Udons Retro Remake imprint has taken the wraps off of its FPGA-powered PlayStation clone, called the SuperStation One. The MiSTer-based console starts at just $149.99 for pre-orders, in what is being billed as a Founders Edition, with subsequent pricing having a hard cap of $225 (also visible in this image of the store page). If you want that SuperSpecial price, pre-orders open at the following times, on the Retro Remake store:Los Angeles: 6 p.m. PST on Saturday, January 25New York: 9 p.m. EST on Saturday, January 25London: 2 a.m. GMT on Sunday, January 26Hong Kong: 10 a.m. HKT on Sunday, January 26Sydney: 1 p.m. AEDT on Sunday, January 26More times here Mark your calendars.It would be uncharacteristic of me to not have this in transparent blue. Should we make it? Taki Udon (@takiudon.bsky.social) 2025-01-23T08:30:25.483ZThe SuperStation One is a custom MiSTer device, housed in a plastic shell that certainly evokes the vibes of the original PlayStation (or, perhaps, the PSOne would be more accurate). While the device will run any of the MiSTers myriad cores, its the projects PSX_MiSTer core that takes center stage here. Coupled with original PlayStation controller and Memory Card ports on the front of the device, and a bevy of other inputs and outputs befitting any MiSTer project, and the SuperStation One makes a compelling alternative to the MiSTers often confusing assembly of hubs and hats and SDRAM and SNAC adapters. With built-in analog output, USB, NFC, wifi, Bluetooth, and SNAC support, Udons console has de-dongled the MiSTer to a really impressive degree.Theres even a power button! (MiSTer users know. )Then theres the question of how you get games on the thing. Retro Remake has teased a separate attachment called the SuperDock, which houses a CD/DVD drive, four USB A ports, and a 2280 m.2 SSD bay, and which appears to fit neatly beneath the SuperStation One.While no pricing has been announced yet, pre-order deposits will be available for $5 alongside a SuperStation One purchase. The design for the SuperDock (D) is almost done. CD/DVD drive, four USB A ports, and a 2280 m.2 SSD bay. Taki Udon (@takiudon.bsky.social) 2025-01-22T00:17:20.685ZIf youd rather skip loading real discs, or would prefer to do what I did and embed small NFC stickers into your cases, the SuperStation One comes equipped with an NFC reader so you can use Zaparoo (ne TapTo) to load games, giving you that tactile console experience. Normally, how you get the ROMs that youll be tapping onto the device is a process best left unspoken, but Udon spoke to the excellent folks at Time Extension about the SuperDocks capabilities here.Thankfully, saving games is split from the media, and our SNAC ports give us the direct ability to load and save games without needing to use cartridge-based workarounds. That just leaves you with how to handle the CD itself. On a stock core with a stock system, it is possible to store your games on an internal SSD via a simple process. Whenever you use that CD in the future, the stock system will call the stored backup and load the game without you needing to do anything.This is a great solution for those of us with large PS1 disc collections, where you could rip your own ROMs, and load them upon disc insertion, or (presumably) NFC tap if youd prefer. While theres still a large open question for how these changes apply upstream to the MiSTer project, its certainly compelling from a user experience standpoint.If all of this reminds you of Analogues excellent clone consoles, well yeah, this is a direct competitor to what Analogue has been up to. While Analogues products are beautiful and simple compared to the complexities of a MiSTer build, they lack the flexibility and Tinker Factor that the MiSTer has. They also lack much to the frustration of many of its customers and fans of its name analog output for CRT support, which the SuperStation One will support. Analogue hasnt gotten around to a PlayStation core yet; its first CD-based system was 2023s excellent, but niche, Analogue Duo and up next is the Analogue 3D, a 4K Nintendo 64 clone which should be shipping this quarter. As much as Ive enjoyed all of Analogues projects, its exciting to see some more competition in this space.