• The worlds smallest handmade sculpture is a blood cell-sized Lego brick
    www.popsci.com
    Lindon's next project is a microscopic animal zoo. Credit: David LindonShareThe new Guinness World Record holder for the smallest hand-made sculpture is so miniscule that you cant even see it with the naked eye. Completed late last year and confirmed this week in a Guinness press announcement, micro-artist David Lindon has managed to build a red Lego brick with dimensions equal roughly to that of a single human white blood cell. Lindon used a specially calibrated light microscope to craft the sculpture that measures just 0.02517mm by 0.02184mm.Each one is built by mounting microblading needles on the ends of instrument screwdrivers, many of which then feature additional microscopic attachments. The tools are made from silicon carbide, a material whose hardness is surpassed only by diamonds.Lindon made three separate Lego bricks in total. Credit: David Lindon The process required months of planning, followed by even more months of painstaking sculpting using a handmade toolset. Lindon worked 6-10 hours at a time, but only at night to lessen the likelihood of disruptions from traffic vibrations. On a personal level, the self-described micro-artist also learned to slow his breathing to work without disturbing the incredibly sensitive construction project.Even the pulse of my heart beating through my fingers creates too much movement, he said in the Guinness World Record announcement.In the end, Lindon actually built three separate Lego brickseach of which are less than the width of a human hair and easily fit on a pinhead. The first, an eight-spot Lego piece is officially recognized as the narrowest handmade structure ever built, while a four-spot brick measured four times smaller than the previous record set in 2017 by Lindons friend and fellow micro artist Willard Wigan. His final sculpture, a single-dot Lego brick, also became his quickest project yet by around 20 minutes. Get the Popular Science newsletter Breakthroughs, discoveries, and DIY tips sent every weekday. By signing up you agree to our Terms of Service and Privacy Policy.Lindon, a former engineer for the UKs Ministry of Defense, first began working on micro-sculptures in 2019, and soon created pieces such as miniature recreations of Van Gogh paintings that fit on a watch mechanism. Follow-up projects included micro balloon dogs similar to those made famous by artist Jeff Koons.According to the BBC, Lindon isnt planning on sticking with microscopic recreations of classic toys. His next project scheduled to release later this year, The Smallest Zoo in the World, will include an animal menagerie sculpted into the eyes of needles.
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  • Fired federal workers share the crucial jobs no longer being done
    www.sciencenews.org
    Jim Landahl, a National Park Service biological science technician, spent Friday, February 14, moving willow trees from a nursery to a helipad in Grand Canyon National Park. The trees were part of efforts to restore vegetation at a popular campground located at the base of the canyon, where temperatures can reach around 49 Celsius (120 Fahrenheit). The trees were to provide privacy and much-needed shade for visitors.But before he could hike 12 kilometers down to the campground to start planting the trees, Landahl a probationary employee learned that his job had been terminated.Landahl is among thousands of employees, including many scientists, across government agencies who have recently been fired in a push by the Trump administration to reduce the federal workforce. The efforts, spearheaded by Elon Musk and the Department of Government Efficiency, take aim at probationary employees in the federal government, those within around one to three years of starting a new job. More than 200,000 federal workers had less than one year of service in the federal government in June 2024 the latest data available at the time of publication according to the Office of Personnel Management.Employees at health agencies, including the Centers for Disease Control and Prevention, the National Institutes of Health and the Food and Drug Administration, are among those affected. The terminations, as well as other moves to cut science-related spending, have led to confusion and concern about public health and safety and the environment both within and outside of the government.For instance, many members of the CDCs Epidemic Intelligence Service a competitive program that trains disease detectives to respond to outbreaks were reportedly warned February 14 that their positions were being terminated, leading to outcries by scientists. The program since has apparently been spared.At the U.S. Department of Agriculture, employees working on the response to bird flu reportedly received termination letters, only for the department to then scramble to rescind the firings.Past presidents have shrunk the overall federal workforce, but not in such a quick, sweeping manner, and rarely in ways that have so deeply affected federal support for science. No president has ever done anything like this, says science historian Naomi Oreskes of Harvard University. Although there have previously been debates about the role and extent of science agencies, she notes, both Republican and Democratic presidents since the U.S. Civil War have by and large supported science in the federal government.To better understand the jobs of people affected by these firings, as well their impact on health, safety and popular programs like the national parks, Science News spoke to employees across the federal government whose science-related jobs have been terminated.Science outreach at NIHOne month into her job at the National Human Genome Research Institute in Bethesda, Md., Katie Sandlin received official word about her impending termination. Sandlin had just moved from Alabama for her new role as an outreach education specialist. There, she helped create activities and resources not only to inspire students, but also for the general public and health workers to better interpret genomic and genetic data. For instance, she says, people can easily order DNA tests to their doorsteps these days, and they may seek guidance on what the results mean.Further, many health care providers havent been extensively trained in genomic or genetic analysis, Sandlin notes. We want to make sure that theyre equipped with the right information to help their patients.Such resources help emphasize that two people with the same health issue may need different treatments tailored to unique characteristics embedded in their DNA. Its part of a larger push toward personalized medicine. In order to reach that [understanding], youve got to educate students, youve got to train their teachers, youve got to inform health care providers, Sandlin says. If were not there doing it, its not going to happen.Sponsor MessageProtecting waterways with the U.S. Forest ServiceIn the Tongass National Forest in southeast Alaska, Anna Tollfeldt scouted streams as part of her job as a biological technician at the U.S. Forest Services office in Wrangell. She mapped the waterways to ensure logging didnt take place too close to fish-bearing streams, which receive special protections. Those areas require a certain amount of shade and plant diversity to provide adequate temperatures and food for fish, particularly salmon, to thrive, Tollfeldt says.Salmon, including sockeye salmon (shown), are a vital resource in southeast Alaska. Anna Tollfeldt helped to map fish-bearing streams to ensure the surrounding areas were protected from logging. Thomas Kline/Design Pics/Getty ImagesShe also worked with a local tribe, the Wrangell Cooperative Association, to identify previously logged areas that should be restored to make the streams healthier for salmon. We do need wood; logging does need to occur, Tollfeldt says. But it needs to be done responsibly if we want other resources, such as salmon, which is incredibly important here as a subsistence food and to the culture.Tollfeldt was born and raised in southeast Alaska and hired by the Forest Service in July 2023 through a program that preferentially selects local residents. These communities are really small, and theyre really expensive to move to, Tollfeldt says. Theres also little to do in Wrangell, a town with roughly 2,000 people. Around a quarter of the employees were fired from Tollfeldts office of about 25 permanent workers. When you remove that many people, that impact is big here in Wrangell.Assessing the safety of medical devices at FDAAmong its many roles, FDA reviews medical devices for safety and performance. But many of the people responsible for those reviews reportedly as many as 200 were fired. One reviewer, who asked for Science News not to use their name for fear of retaliation, says they were in the midst of reviewing a submission from a company seeking FDA clearance of a new device when they got their termination letter on Saturday, February 15.It cited poor performance as the reason for being fired from FDAs Center for Devices and Radiological Health. But the reviewer noted that they regularly worked long hours to handle the overwhelming amount of materials. I work on Saturdays because of the load of these submissions, the reviewer says.At first glance, some technologies look incredible, the fired reviewer says. For example, one may claim an artificial intelligenceenabled device that aids disease detection would reduce the amount of radiation patients are exposed to during CT scans. But further examination of the methods used to create the device might reveal fatal flaws.The mass firing may have dire consequences if medical devices are no longer as rigorously examined, the reviewer says. Inaccuracies when detecting or diagnosing diseases can have disastrous effects. If a cancer diagnosis is delayed, the reviewer says, the cancer could spread and move into a more deadly stage before being identified. The American public [is] going to face the consequences if those unsafe devices are going to be in the market.Protecting habitat and spotting bird flu deaths for the U.S. Fish and Wildlife ServiceWhen Harlan Gough took a job at Columbia National Wildlife Refuge in his home state of Washington last year, he was excited to do work that he found meaningful as a wildlife biologist.The job involved managing habitat and doing conservation work for waterfowl like ducks, including warding off invasive species that would otherwise completely swamp wetlands at the refuge. At one point, Gough recalls clearing out debris that a beaver had stuffed into a culvert, which had in turn flooded public roads.Coordinating with officials from USDA to respond to waterfowl affected by bird flu was also part of Goughs job. Hes witnessed die-offs of dozens of geese that appear to have succumbed to the virus. Some dead animals have even popped up in towns near the refuge.Gough worries that with his firing, there may not be people to continue the work he was doing at the refuge, which is also a popular hunting ground. He suspects that avid birders and hunters may be the first to witness environmental degradation at the refuge caused by a lack of personnel.My worry is that this is not the end, but only the beginning, for the trouble for these federal agencies that manage our natural areas and conduct science, Gough says.Mapping airspace at the Federal Aviation AdministrationPilots and air traffic controllers consult flight maps on a minute-by-minute basis to avoid disasters, such as the Jan. 29 plane crash at Ronald Reagan Washington National Airport. But several cartographers who create and maintain those maps, formally called aeronautical information specialists, at the FAA received termination letters in mid-February, according to one cartographer. They requested that Science News not use their name for fear of retaliation.Our work is strictly critical public safety and keeping our nations airspace safe, the cartographer says. I honestly did think that we might have been safe from the firings given our critical positions.The FAA, part of the Department of Transportation, is the only group authorized to create U.S. airspace maps, the cartographer says. The job requires highly specialized training and knowledge. If you look at just a square inch on the map, you will see over 30 symbols just in that area, the cartographer notes.Airspace cartographers were among the fired federal employees. Pilots and air traffic controllers rely on maps made by these cartographers (like the map shown) to avoid flight disasters.FAAWe not only have to learn the symbology, we have to learn the meaning behind it. For instance, certain symbols tell pilots where they must report their location to air traffic control to ensure the plane is on a safe and efficient route and to avoid congesting airways.The cartographer worries about pilots and others lacking information needed for flight. When the team creating such maps becomes understaffed and overstressed, the cartographer says, thats where mistakes can start to happen. And those mistakes would be widespread.Protecting visitors and the environment for the National Park ServiceInstead of planting trees at the foot of one of Americas most popular national parks, Landahl spent the week after he was fired speaking out on behalf of his community. As a biological science technician at Grand Canyon National Park, Landahl was tasked with leading efforts to restore vegetation affected by upgrades to a pipeline that shuttles water across the canyon. Hedges used to provide privacy and shade at a campground at the bottom of the canyon.Jim Landahl moved willow trees from a nursery to a helipad on the day he was fired.Jim LandahlEfforts to restore vegetation at the campground are now on hold with the firings, Landahl says, calling the need for shade a public safety issue. Rather than preventing waste a reported goal of the government downsizing the unexpected nature of the termination led to a waste of resources, he says.We were ready to keep working on Saturday and Sunday to get this project off the ground, Landahl says. I was supposed to be in the canyon right now, planting and getting that work done for the American public, but it was a waste of money, and it was a waste of time the way they did that.Landahl was also responsible for assisting the nursery and greenhouse, managing invasive species and organizing programs for a local Grand Canyon public school.Were out in the field, out in the desert, grinding it out, doing our lifes work, doing work for the country, doing work for the American public to keep their country looking great, Landahl says. When you kick a small American town like ours, and you make impacts to those communities, you really kick a bees nest with us. We take it personally.
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  • Reply to: Insufficient evidence for natural selection associated with the Black Death
    www.nature.com
    Nature, Published online: 19 February 2025; doi:10.1038/s41586-024-08497-4Reply to: Insufficient evidence for natural selection associated with the Black Death
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  • Reconstitution of SPO11-dependent double-strand break formation
    www.nature.com
    Nature, Published online: 19 February 2025; doi:10.1038/s41586-025-08601-2Reconstitution of recombinantly expressed SPO11TOP6BL complex recapitulates its DNA cleavage function and together with structural modelling and biochemical experiments, provides insights into the regulation and mechanism of SPO11 activity.
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  • 3D Artist Egor Ivanov presented a comprehensive step-by-step tutorial on creating a samurai mask using ZBrush, Maya, Substance 3D Painter, and Marmose...
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    3D Artist Egor Ivanov presented a comprehensive step-by-step tutorial on creating a samurai mask using ZBrush, Maya, Substance 3D Painter, and Marmoset, sharing valuable tips for achieving an impressive look and a simple yet effective approach to lighting.Read here: https://80.lv/articles/how-to-model-texture-a-samurai-mask-with-menacing-facial-features/
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  • Adobe released Substance 3D Sampler 5.0, introducing a new path tracing viewport renderer, native support for HP's Z Captis material scanner, and more...
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    Adobe released Substance 3D Sampler 5.0, introducing a new path tracing viewport renderer, native support for HP's Z Captis material scanner, and more.Details: https://80.lv/articles/adobe-launched-substance-3d-sampler-5-0/
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  • RT HUXLEY: The Titans unleashed wrath and fury during the old wars...The planet hasn't been the same since. #scifi #warmachine #titans
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    RTHUXLEYThe Titans unleashed wrath and fury during the old wars...The planet hasn't been the same since.#scifi #warmachine #titans
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    Step into a world of floral fantasy with @bellakotak. For 35 years, Photoshop has been redefining creativitysee how she transforms portraits into breathtaking dreamscapes where beauty, color, and imagination collide. https://adobe.ly/4gUF5Zw
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    For 35 years, Adobe Photoshop has been redefining creativityand Holly Rose Stones is doing the same. Using Photoshop, she transforms personal stories into bold, colorful self-portraits that make you feel. https://adobe.ly/4iaIHrD
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