• Trump admin tells Supreme Court: DOGE needs to do its work in secret

    DOGE in court

    Trump admin tells Supreme Court: DOGE needs to do its work in secret

    DOJ complains of "sweeping, intrusive discovery" after DOGE refused FOIA requests.

    Jon Brodkin



    May 21, 2025 5:08 pm

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    73

    A protest over DOGE's reductions to the federal workforce outside the Jacob K. Javits Federal Office Building on March 19, 2025 in New York City.

    Credit:

    Getty Images | Michael M. Santiago

    A protest over DOGE's reductions to the federal workforce outside the Jacob K. Javits Federal Office Building on March 19, 2025 in New York City.

    Credit:

    Getty Images | Michael M. Santiago

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    The Department of Justice today asked the Supreme Court to block a ruling that requires DOGE to provide information about its government cost-cutting operations as part of court-ordered discovery.
    President Trump's Justice Department sought an immediate halt to orders issued by US District Court for the District of Columbia. US Solicitor General John Sauer argued that the Department of Government Efficiency is exempt from the Freedom of Information Actas a presidential advisory body and not an official "agency."
    The district court "ordered USDSto submit to sweeping, intrusive discovery just to determine if USDS is subject to FOIA in the first place," Sauer wrote. "That order turns FOIA on its head, effectively giving respondent a win on the merits of its FOIA suit under the guise of figuring out whether FOIA even applies. And that order clearly violates the separation of powers, subjecting a presidential advisory body to intrusive discovery and threatening the confidentiality and candor of its advice, putatively to address a legal question that never should have necessitated discovery in this case at all."
    The nonprofit watchdog group Citizens for Responsibility and Ethics in Washingtonfiled FOIA requests seeking information about DOGE and sued after DOGE officials refused to provide the requested records.
    US District Judge Christopher Cooper has so far sided with CREW. Cooper decided in March that "USDS is likely covered by FOIA and that the public would be irreparably harmed by an indefinite delay in unearthing the records CREW seeks," ordering DOGE "to process CREW's request on an expedited timetable."

    Judge: DOGE is not just an advisor
    DOGE then asked the district court for a summary judgment in its favor, and CREW responded by filing a motion for expedited discovery "seeking information relevant to whether USDS wields substantial authority independent of the President and is therefore subject to FOIA." In an April 15 order, Cooper ruled that CREW is entitled to limited discovery into the question of whether DOGE is wielding authority sufficient to bring it within the purview of FOIA. Cooper hasn't yet ruled on the motion for summary judgment.
    "The structure of USDS and the scope of its authority are critical to determining whether the agency is 'wieldsubstantial authority independently of the President,'" the judge wrote. "And the answers to those questions are unclear from the record."
    Trump's executive orders appear to support CREW's argument by suggesting "that USDS is exercising substantial independent authority," Cooper wrote. "As the Court already noted, the executive order establishing USDS 'to implement the President's DOGE Agenda' appears to give USDS the authority to carry out that agenda, 'not just to advise the President in doing so.'"
    Not satisfied with the outcome, the Trump administration tried to get Cooper's ruling overturned in the US Court of Appeals for the District of Columbia Circuit. The appeals court ruled against DOGE last week. The appeals court temporarily stayed the district court order in April, but dissolved the stay on May 14 and denied the government's petition.
    "The government contends that the district court's order permitting narrow discovery impermissibly intrudes upon the President's constitutional prerogatives," the appeals court said. But "the discovery here is modest in scope and does not target the President or any close adviser personally. The government retains every conventional tool to raise privilege objections on the limited question-by-question basis foreseen here on a narrow and discrete ground."

    US argues for secrecy
    A three-judge panel at the appeals court was unswayed by the government's claim that this process is too burdensome.
    "Although the government protests that any such assertion of privilege would be burdensome, the only identified burdens are limited both by time and reach, covering as they do records within USDS's control generated since January 20," the ruling said. "It does not provide any specific details as to why accessing its own records or submitting to two depositions would pose an unbearable burden."
    Yesterday, the District Court set a discovery schedule requiring the government to produce all responsive documents within 14 days and complete depositions within 24 days. In its petition to the Supreme Court today, the Trump administration argued that DOGE's recommendations to the president should be kept secret:
    The district court's requirement that USDS turn over the substance of its recommendations—even when the recommendations were "purely advisory"—epitomizes the order's overbreadth and intrusiveness. The court's order compels USDS to identify every "federal agency contract, grant, lease or similar instrument that any DOGE employee or DOGE Team member recommended that federal agencies cancel or rescind," and every "federal agency employee or position that any DOGE employee or DOGE team member recommended" for termination or placement on administrative leave. Further, USDS must state "whetherrecommendation was followed."
    It is difficult to imagine a more grievous intrusion and burden on a presidential advisory body. Providing recommendations is the core of what USDS does. Because USDS coordinates with agencies across the Executive Branch on an ongoing basis, that request requires USDS to review multitudes of discussions that USDS has had every day since the start of this Administration. And such information likely falls within the deliberative-process privilege almost by definition, as internal executive-branch recommendations are inherently "pre-decisional" and "deliberative."
    Lawsuit: “No meaningful transparency” into DOGE
    The US further said the discovery "is unnecessary to answer the legal question whether USDS qualifies as an 'agency' that is subject to FOIA," and is merely "a fishing expedition into USDS's advisory activities under the guise of determining whether USDS engages in non-advisory activities—an approach to discovery that would be improper in any circumstance."

    CREW, like others that have sued the government over DOGE's operations, says the entity exercises significant power without proper oversight and transparency. DOGE "has worked in the shadows—a cadre of largely unidentified actors, whose status as government employees is unclear, controlling major government functions with no oversight," CREW's lawsuit said. "USDS has provided no meaningful transparency into its operations or assurances that it is maintaining proper records of its unprecedented and legally dubious work."
    The Trump administration is fighting numerous DOGE-related lawsuits at multiple levels of the court system. Earlier this month, the administration asked the Supreme Court to restore DOGE's access to Social Security Administration records after losing on the issue in both a district court and appeals court. That request to the Supreme Court is pending.
    There was also a dispute over discovery when 14 states sued the federal government over Trump "delegatvirtually unchecked authority to Mr. Musk without proper legal authorization from Congress and without meaningful supervision of his activities." A federal judge ruled that the states could serve written discovery requests on Musk and DOGE, but the DC Circuit appeals court blocked the discovery order. In that case, appeals court judges said the lower-court judge should have ruled on a motion to dismiss before allowing discovery.

    Jon Brodkin
    Senior IT Reporter

    Jon Brodkin
    Senior IT Reporter

    Jon is a Senior IT Reporter for Ars Technica. He covers the telecom industry, Federal Communications Commission rulemakings, broadband consumer affairs, court cases, and government regulation of the tech industry.

    73 Comments
    #trump #admin #tells #supreme #court
    Trump admin tells Supreme Court: DOGE needs to do its work in secret
    DOGE in court Trump admin tells Supreme Court: DOGE needs to do its work in secret DOJ complains of "sweeping, intrusive discovery" after DOGE refused FOIA requests. Jon Brodkin – May 21, 2025 5:08 pm | 73 A protest over DOGE's reductions to the federal workforce outside the Jacob K. Javits Federal Office Building on March 19, 2025 in New York City. Credit: Getty Images | Michael M. Santiago A protest over DOGE's reductions to the federal workforce outside the Jacob K. Javits Federal Office Building on March 19, 2025 in New York City. Credit: Getty Images | Michael M. Santiago Story text Size Small Standard Large Width * Standard Wide Links Standard Orange * Subscribers only   Learn more The Department of Justice today asked the Supreme Court to block a ruling that requires DOGE to provide information about its government cost-cutting operations as part of court-ordered discovery. President Trump's Justice Department sought an immediate halt to orders issued by US District Court for the District of Columbia. US Solicitor General John Sauer argued that the Department of Government Efficiency is exempt from the Freedom of Information Actas a presidential advisory body and not an official "agency." The district court "ordered USDSto submit to sweeping, intrusive discovery just to determine if USDS is subject to FOIA in the first place," Sauer wrote. "That order turns FOIA on its head, effectively giving respondent a win on the merits of its FOIA suit under the guise of figuring out whether FOIA even applies. And that order clearly violates the separation of powers, subjecting a presidential advisory body to intrusive discovery and threatening the confidentiality and candor of its advice, putatively to address a legal question that never should have necessitated discovery in this case at all." The nonprofit watchdog group Citizens for Responsibility and Ethics in Washingtonfiled FOIA requests seeking information about DOGE and sued after DOGE officials refused to provide the requested records. US District Judge Christopher Cooper has so far sided with CREW. Cooper decided in March that "USDS is likely covered by FOIA and that the public would be irreparably harmed by an indefinite delay in unearthing the records CREW seeks," ordering DOGE "to process CREW's request on an expedited timetable." Judge: DOGE is not just an advisor DOGE then asked the district court for a summary judgment in its favor, and CREW responded by filing a motion for expedited discovery "seeking information relevant to whether USDS wields substantial authority independent of the President and is therefore subject to FOIA." In an April 15 order, Cooper ruled that CREW is entitled to limited discovery into the question of whether DOGE is wielding authority sufficient to bring it within the purview of FOIA. Cooper hasn't yet ruled on the motion for summary judgment. "The structure of USDS and the scope of its authority are critical to determining whether the agency is 'wieldsubstantial authority independently of the President,'" the judge wrote. "And the answers to those questions are unclear from the record." Trump's executive orders appear to support CREW's argument by suggesting "that USDS is exercising substantial independent authority," Cooper wrote. "As the Court already noted, the executive order establishing USDS 'to implement the President's DOGE Agenda' appears to give USDS the authority to carry out that agenda, 'not just to advise the President in doing so.'" Not satisfied with the outcome, the Trump administration tried to get Cooper's ruling overturned in the US Court of Appeals for the District of Columbia Circuit. The appeals court ruled against DOGE last week. The appeals court temporarily stayed the district court order in April, but dissolved the stay on May 14 and denied the government's petition. "The government contends that the district court's order permitting narrow discovery impermissibly intrudes upon the President's constitutional prerogatives," the appeals court said. But "the discovery here is modest in scope and does not target the President or any close adviser personally. The government retains every conventional tool to raise privilege objections on the limited question-by-question basis foreseen here on a narrow and discrete ground." US argues for secrecy A three-judge panel at the appeals court was unswayed by the government's claim that this process is too burdensome. "Although the government protests that any such assertion of privilege would be burdensome, the only identified burdens are limited both by time and reach, covering as they do records within USDS's control generated since January 20," the ruling said. "It does not provide any specific details as to why accessing its own records or submitting to two depositions would pose an unbearable burden." Yesterday, the District Court set a discovery schedule requiring the government to produce all responsive documents within 14 days and complete depositions within 24 days. In its petition to the Supreme Court today, the Trump administration argued that DOGE's recommendations to the president should be kept secret: The district court's requirement that USDS turn over the substance of its recommendations—even when the recommendations were "purely advisory"—epitomizes the order's overbreadth and intrusiveness. The court's order compels USDS to identify every "federal agency contract, grant, lease or similar instrument that any DOGE employee or DOGE Team member recommended that federal agencies cancel or rescind," and every "federal agency employee or position that any DOGE employee or DOGE team member recommended" for termination or placement on administrative leave. Further, USDS must state "whetherrecommendation was followed." It is difficult to imagine a more grievous intrusion and burden on a presidential advisory body. Providing recommendations is the core of what USDS does. Because USDS coordinates with agencies across the Executive Branch on an ongoing basis, that request requires USDS to review multitudes of discussions that USDS has had every day since the start of this Administration. And such information likely falls within the deliberative-process privilege almost by definition, as internal executive-branch recommendations are inherently "pre-decisional" and "deliberative." Lawsuit: “No meaningful transparency” into DOGE The US further said the discovery "is unnecessary to answer the legal question whether USDS qualifies as an 'agency' that is subject to FOIA," and is merely "a fishing expedition into USDS's advisory activities under the guise of determining whether USDS engages in non-advisory activities—an approach to discovery that would be improper in any circumstance." CREW, like others that have sued the government over DOGE's operations, says the entity exercises significant power without proper oversight and transparency. DOGE "has worked in the shadows—a cadre of largely unidentified actors, whose status as government employees is unclear, controlling major government functions with no oversight," CREW's lawsuit said. "USDS has provided no meaningful transparency into its operations or assurances that it is maintaining proper records of its unprecedented and legally dubious work." The Trump administration is fighting numerous DOGE-related lawsuits at multiple levels of the court system. Earlier this month, the administration asked the Supreme Court to restore DOGE's access to Social Security Administration records after losing on the issue in both a district court and appeals court. That request to the Supreme Court is pending. There was also a dispute over discovery when 14 states sued the federal government over Trump "delegatvirtually unchecked authority to Mr. Musk without proper legal authorization from Congress and without meaningful supervision of his activities." A federal judge ruled that the states could serve written discovery requests on Musk and DOGE, but the DC Circuit appeals court blocked the discovery order. In that case, appeals court judges said the lower-court judge should have ruled on a motion to dismiss before allowing discovery. Jon Brodkin Senior IT Reporter Jon Brodkin Senior IT Reporter Jon is a Senior IT Reporter for Ars Technica. He covers the telecom industry, Federal Communications Commission rulemakings, broadband consumer affairs, court cases, and government regulation of the tech industry. 73 Comments #trump #admin #tells #supreme #court
    Trump admin tells Supreme Court: DOGE needs to do its work in secret
    arstechnica.com
    DOGE in court Trump admin tells Supreme Court: DOGE needs to do its work in secret DOJ complains of "sweeping, intrusive discovery" after DOGE refused FOIA requests. Jon Brodkin – May 21, 2025 5:08 pm | 73 A protest over DOGE's reductions to the federal workforce outside the Jacob K. Javits Federal Office Building on March 19, 2025 in New York City. Credit: Getty Images | Michael M. Santiago A protest over DOGE's reductions to the federal workforce outside the Jacob K. Javits Federal Office Building on March 19, 2025 in New York City. Credit: Getty Images | Michael M. Santiago Story text Size Small Standard Large Width * Standard Wide Links Standard Orange * Subscribers only   Learn more The Department of Justice today asked the Supreme Court to block a ruling that requires DOGE to provide information about its government cost-cutting operations as part of court-ordered discovery. President Trump's Justice Department sought an immediate halt to orders issued by US District Court for the District of Columbia. US Solicitor General John Sauer argued that the Department of Government Efficiency is exempt from the Freedom of Information Act (FOIA) as a presidential advisory body and not an official "agency." The district court "ordered USDS [US Doge Service] to submit to sweeping, intrusive discovery just to determine if USDS is subject to FOIA in the first place," Sauer wrote. "That order turns FOIA on its head, effectively giving respondent a win on the merits of its FOIA suit under the guise of figuring out whether FOIA even applies. And that order clearly violates the separation of powers, subjecting a presidential advisory body to intrusive discovery and threatening the confidentiality and candor of its advice, putatively to address a legal question that never should have necessitated discovery in this case at all." The nonprofit watchdog group Citizens for Responsibility and Ethics in Washington (CREW) filed FOIA requests seeking information about DOGE and sued after DOGE officials refused to provide the requested records. US District Judge Christopher Cooper has so far sided with CREW. Cooper decided in March that "USDS is likely covered by FOIA and that the public would be irreparably harmed by an indefinite delay in unearthing the records CREW seeks," ordering DOGE "to process CREW's request on an expedited timetable." Judge: DOGE is not just an advisor DOGE then asked the district court for a summary judgment in its favor, and CREW responded by filing a motion for expedited discovery "seeking information relevant to whether USDS wields substantial authority independent of the President and is therefore subject to FOIA." In an April 15 order, Cooper ruled that CREW is entitled to limited discovery into the question of whether DOGE is wielding authority sufficient to bring it within the purview of FOIA. Cooper hasn't yet ruled on the motion for summary judgment. "The structure of USDS and the scope of its authority are critical to determining whether the agency is 'wield[ing] substantial authority independently of the President,'" the judge wrote. "And the answers to those questions are unclear from the record." Trump's executive orders appear to support CREW's argument by suggesting "that USDS is exercising substantial independent authority," Cooper wrote. "As the Court already noted, the executive order establishing USDS 'to implement the President's DOGE Agenda' appears to give USDS the authority to carry out that agenda, 'not just to advise the President in doing so.'" Not satisfied with the outcome, the Trump administration tried to get Cooper's ruling overturned in the US Court of Appeals for the District of Columbia Circuit. The appeals court ruled against DOGE last week. The appeals court temporarily stayed the district court order in April, but dissolved the stay on May 14 and denied the government's petition. "The government contends that the district court's order permitting narrow discovery impermissibly intrudes upon the President's constitutional prerogatives," the appeals court said. But "the discovery here is modest in scope and does not target the President or any close adviser personally. The government retains every conventional tool to raise privilege objections on the limited question-by-question basis foreseen here on a narrow and discrete ground." US argues for secrecy A three-judge panel at the appeals court was unswayed by the government's claim that this process is too burdensome. "Although the government protests that any such assertion of privilege would be burdensome, the only identified burdens are limited both by time and reach, covering as they do records within USDS's control generated since January 20," the ruling said. "It does not provide any specific details as to why accessing its own records or submitting to two depositions would pose an unbearable burden." Yesterday, the District Court set a discovery schedule requiring the government to produce all responsive documents within 14 days and complete depositions within 24 days. In its petition to the Supreme Court today, the Trump administration argued that DOGE's recommendations to the president should be kept secret: The district court's requirement that USDS turn over the substance of its recommendations—even when the recommendations were "purely advisory"—epitomizes the order's overbreadth and intrusiveness. The court's order compels USDS to identify every "federal agency contract, grant, lease or similar instrument that any DOGE employee or DOGE Team member recommended that federal agencies cancel or rescind," and every "federal agency employee or position that any DOGE employee or DOGE team member recommended" for termination or placement on administrative leave. Further, USDS must state "whether [each] recommendation was followed." It is difficult to imagine a more grievous intrusion and burden on a presidential advisory body. Providing recommendations is the core of what USDS does. Because USDS coordinates with agencies across the Executive Branch on an ongoing basis, that request requires USDS to review multitudes of discussions that USDS has had every day since the start of this Administration. And such information likely falls within the deliberative-process privilege almost by definition, as internal executive-branch recommendations are inherently "pre-decisional" and "deliberative." Lawsuit: “No meaningful transparency” into DOGE The US further said the discovery "is unnecessary to answer the legal question whether USDS qualifies as an 'agency' that is subject to FOIA," and is merely "a fishing expedition into USDS's advisory activities under the guise of determining whether USDS engages in non-advisory activities—an approach to discovery that would be improper in any circumstance." CREW, like others that have sued the government over DOGE's operations, says the entity exercises significant power without proper oversight and transparency. DOGE "has worked in the shadows—a cadre of largely unidentified actors, whose status as government employees is unclear, controlling major government functions with no oversight," CREW's lawsuit said. "USDS has provided no meaningful transparency into its operations or assurances that it is maintaining proper records of its unprecedented and legally dubious work." The Trump administration is fighting numerous DOGE-related lawsuits at multiple levels of the court system. Earlier this month, the administration asked the Supreme Court to restore DOGE's access to Social Security Administration records after losing on the issue in both a district court and appeals court. That request to the Supreme Court is pending. There was also a dispute over discovery when 14 states sued the federal government over Trump "delegat[ing] virtually unchecked authority to Mr. Musk without proper legal authorization from Congress and without meaningful supervision of his activities." A federal judge ruled that the states could serve written discovery requests on Musk and DOGE, but the DC Circuit appeals court blocked the discovery order. In that case, appeals court judges said the lower-court judge should have ruled on a motion to dismiss before allowing discovery. Jon Brodkin Senior IT Reporter Jon Brodkin Senior IT Reporter Jon is a Senior IT Reporter for Ars Technica. He covers the telecom industry, Federal Communications Commission rulemakings, broadband consumer affairs, court cases, and government regulation of the tech industry. 73 Comments
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  • Extra cancer screening could help pick up early cases in dense breasts

    Dense breast tissue and tumours appear similar on scans, which can make the latter hard to identifyGorodenkoff/Shutterstock
    If you have dense breast tissue, you could benefit from an extra round of cancer screening, according to a large trial that found this caught tumours that were missed in standard mammograms.
    The UK’s health services offer mammograms, a form of X-ray scan, between the ages of 50 and 71 in order to screen for breast cancer. These look for white growths that are indicative of cancer. But about half of women in this age group have dense breasts, meaning they have a high proportion of fibrous and glandular tissue, which also shows up as white on the scans. This can make tumours harder to spot in these individuals.
    Advertisement
    “The problem with dense breasts is we see cancers too late, then they are too big and this leads to an unfavourable prognosis,” says Thomas Helbich at the Medical University of Vienna in Austria, who wasn’t involved in the trial.
    To see if additional screening could address this, Sarah Vinnicombe at the University of Dundee, UK, and her colleagues recruited more than 6000 women aged 50 to 70 from across the UK who had dense breasts and whose mammograms came back clear in their most recent screening. The researchers randomly split the participants into three groups that received additional screening in the form of either an MRI, an ultrasound or an advanced form of X-ray scan called contrast-enhanced mammography.
    The extra screening collectively detected 85 small tumours, with MRI and contrast-enhanced mammography detecting three times more tumours than ultrasound. Twelve of these tumours were contained within milk ducts and so were unlikely to spread beyond the breast. But the remaining 73 tumours were invasive, when cancer cells have grown through the lining of the ducts into the surrounding breast tissue and then have greater potential to spread further.

    Get the most essential health and fitness news in your inbox every Saturday.

    Sign up to newsletter

    “It’s very important to find these cancers; usually they are growing and if you detect them three, four years later, they are going to be bigger in size,” says Helbich. “As some will be aggressive, I’m pretty sure that supplemental screening would save lives.”
    But we don’t know if this would definitely be the case. For instance, a 2021 trial of ovarian cancer screening led to a reduced incidence of the condition, but didn’t translate into lives being saved. It is also possible that some of the detected tumours are non-cancerous or unlikely to spread. If this is the case, supplemental screening could lead to unnecessary worry or treatment.
    The team plans to continuing tracking the participants to help gauge if extra screening helps saves lives and if that could justify the cost of rolling it out, says Vinnicombe.
    Journal reference:The Lancet DOI: 10.1016/S0140-673600582-3
    Topics:cancer
    #extra #cancer #screening #could #help
    Extra cancer screening could help pick up early cases in dense breasts
    Dense breast tissue and tumours appear similar on scans, which can make the latter hard to identifyGorodenkoff/Shutterstock If you have dense breast tissue, you could benefit from an extra round of cancer screening, according to a large trial that found this caught tumours that were missed in standard mammograms. The UK’s health services offer mammograms, a form of X-ray scan, between the ages of 50 and 71 in order to screen for breast cancer. These look for white growths that are indicative of cancer. But about half of women in this age group have dense breasts, meaning they have a high proportion of fibrous and glandular tissue, which also shows up as white on the scans. This can make tumours harder to spot in these individuals. Advertisement “The problem with dense breasts is we see cancers too late, then they are too big and this leads to an unfavourable prognosis,” says Thomas Helbich at the Medical University of Vienna in Austria, who wasn’t involved in the trial. To see if additional screening could address this, Sarah Vinnicombe at the University of Dundee, UK, and her colleagues recruited more than 6000 women aged 50 to 70 from across the UK who had dense breasts and whose mammograms came back clear in their most recent screening. The researchers randomly split the participants into three groups that received additional screening in the form of either an MRI, an ultrasound or an advanced form of X-ray scan called contrast-enhanced mammography. The extra screening collectively detected 85 small tumours, with MRI and contrast-enhanced mammography detecting three times more tumours than ultrasound. Twelve of these tumours were contained within milk ducts and so were unlikely to spread beyond the breast. But the remaining 73 tumours were invasive, when cancer cells have grown through the lining of the ducts into the surrounding breast tissue and then have greater potential to spread further. Get the most essential health and fitness news in your inbox every Saturday. Sign up to newsletter “It’s very important to find these cancers; usually they are growing and if you detect them three, four years later, they are going to be bigger in size,” says Helbich. “As some will be aggressive, I’m pretty sure that supplemental screening would save lives.” But we don’t know if this would definitely be the case. For instance, a 2021 trial of ovarian cancer screening led to a reduced incidence of the condition, but didn’t translate into lives being saved. It is also possible that some of the detected tumours are non-cancerous or unlikely to spread. If this is the case, supplemental screening could lead to unnecessary worry or treatment. The team plans to continuing tracking the participants to help gauge if extra screening helps saves lives and if that could justify the cost of rolling it out, says Vinnicombe. Journal reference:The Lancet DOI: 10.1016/S0140-673600582-3 Topics:cancer #extra #cancer #screening #could #help
    Extra cancer screening could help pick up early cases in dense breasts
    www.newscientist.com
    Dense breast tissue and tumours appear similar on scans, which can make the latter hard to identifyGorodenkoff/Shutterstock If you have dense breast tissue, you could benefit from an extra round of cancer screening, according to a large trial that found this caught tumours that were missed in standard mammograms. The UK’s health services offer mammograms, a form of X-ray scan, between the ages of 50 and 71 in order to screen for breast cancer. These look for white growths that are indicative of cancer. But about half of women in this age group have dense breasts, meaning they have a high proportion of fibrous and glandular tissue, which also shows up as white on the scans. This can make tumours harder to spot in these individuals. Advertisement “The problem with dense breasts is we see cancers too late, then they are too big and this leads to an unfavourable prognosis,” says Thomas Helbich at the Medical University of Vienna in Austria, who wasn’t involved in the trial. To see if additional screening could address this, Sarah Vinnicombe at the University of Dundee, UK, and her colleagues recruited more than 6000 women aged 50 to 70 from across the UK who had dense breasts and whose mammograms came back clear in their most recent screening. The researchers randomly split the participants into three groups that received additional screening in the form of either an MRI, an ultrasound or an advanced form of X-ray scan called contrast-enhanced mammography. The extra screening collectively detected 85 small tumours, with MRI and contrast-enhanced mammography detecting three times more tumours than ultrasound. Twelve of these tumours were contained within milk ducts and so were unlikely to spread beyond the breast. But the remaining 73 tumours were invasive, when cancer cells have grown through the lining of the ducts into the surrounding breast tissue and then have greater potential to spread further. Get the most essential health and fitness news in your inbox every Saturday. Sign up to newsletter “It’s very important to find these cancers; usually they are growing and if you detect them three, four years later, they are going to be bigger in size,” says Helbich. “As some will be aggressive, I’m pretty sure that supplemental screening would save lives.” But we don’t know if this would definitely be the case. For instance, a 2021 trial of ovarian cancer screening led to a reduced incidence of the condition, but didn’t translate into lives being saved. It is also possible that some of the detected tumours are non-cancerous or unlikely to spread. If this is the case, supplemental screening could lead to unnecessary worry or treatment. The team plans to continuing tracking the participants to help gauge if extra screening helps saves lives and if that could justify the cost of rolling it out, says Vinnicombe. Journal reference:The Lancet DOI: 10.1016/S0140-6736(25)00582-3 Topics:cancer
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  • Klarna's CEO leans into his company's image, using an AI doppelganger to deliver earnings highlights

    Klarna said it used an AI doppelganger of CEO Sebastian Siemiatkowski to report its updated quarterly earnings.

    Klarna

    2025-05-22T02:31:59Z

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    Klarna said it used an AI avatar of its CEO to report quarterly earnings in a YouTube video.
    Klarna brands itself as an AI company and has "streamlined" its workforce by 40% since 2022.
    Klarna's Q1 results show revenue growth but see a spike in net and credit losses.

    Buy now, pay later services company Klarna said it used an AI doppelganger of CEO Sebastian Siemiatkowski to report its quarterly earnings on Monday.The AI avatar appeared in a video on Klarna's official YouTube channel to deliver earnings highlights. It wore a brown jacket reminiscent of one in Siemiatkowski's corporate headshots, and aside from a lack of blinking and suspect"Our AI-first strategy is driving exceptional returns, we're outpacing competitors, our merchant network is scaling rapidly, and our next-gen products are reshaping money management for millions," a presumably human Siemiatkowski said in a press release.The move comes as Klarna, which last month put its IPO on ice due to economic uncertainty, tries to brand itself as an AI company. In the earnings press release, Klarna said it has "streamlined" its workforce by around 40% since 2022.In 2022, 800 employees were fired, while some were quietly offered an exit package last year after being placed into a "talent pool." In February 2024, Klarna announced that itsKlarna has recently ramped up partnerships with platforms like Walmart, eBay, and DoorDash, but consumer watchdogs have long been concerned about the potential for overspending under BNPL services. Under the Biden administration, theBNPL providers as credit card lenders, which required stricter protections around disclosures and disputes.The Federal Reserve found in 2024 that users of BNPL services are more likely to rely on high-interest financing tools and are more financially fragile.LendingTree, an online lending marketplace, also found in an April survey that 41% of BNPL users in the US paid late over the last 12 months, up from 34% a year ago.Klarna's latest Q1 results also show that an increasing number of people may not have been paying their loans. While revenue grew 13% year over year and it reached 100 million active users, Klarna also doubled its net losses from million in Q1 2024 to million in Q1 2025 — a 110% increase.During the May 19 earnings call, Klarna attributed the spike in losses to several one-off costs related to depreciation, share-based payments, and restructuring.Klarna's consumer credit losses have also jumped, which its Q1 financial report said is "driven by the accelerated expansion of Pay Later and Fair Financing products." Klarna's first quarter saw a 17% year-on-year increase in credit losses from million to million.Klarna did not immediately respond to requests for comment.
    #klarna039s #ceo #leans #into #his
    Klarna's CEO leans into his company's image, using an AI doppelganger to deliver earnings highlights
    Klarna said it used an AI doppelganger of CEO Sebastian Siemiatkowski to report its updated quarterly earnings. Klarna 2025-05-22T02:31:59Z d Read in app This story is available exclusively to Business Insider subscribers. Become an Insider and start reading now. Have an account? Klarna said it used an AI avatar of its CEO to report quarterly earnings in a YouTube video. Klarna brands itself as an AI company and has "streamlined" its workforce by 40% since 2022. Klarna's Q1 results show revenue growth but see a spike in net and credit losses. Buy now, pay later services company Klarna said it used an AI doppelganger of CEO Sebastian Siemiatkowski to report its quarterly earnings on Monday.The AI avatar appeared in a video on Klarna's official YouTube channel to deliver earnings highlights. It wore a brown jacket reminiscent of one in Siemiatkowski's corporate headshots, and aside from a lack of blinking and suspect"Our AI-first strategy is driving exceptional returns, we're outpacing competitors, our merchant network is scaling rapidly, and our next-gen products are reshaping money management for millions," a presumably human Siemiatkowski said in a press release.The move comes as Klarna, which last month put its IPO on ice due to economic uncertainty, tries to brand itself as an AI company. In the earnings press release, Klarna said it has "streamlined" its workforce by around 40% since 2022.In 2022, 800 employees were fired, while some were quietly offered an exit package last year after being placed into a "talent pool." In February 2024, Klarna announced that itsKlarna has recently ramped up partnerships with platforms like Walmart, eBay, and DoorDash, but consumer watchdogs have long been concerned about the potential for overspending under BNPL services. Under the Biden administration, theBNPL providers as credit card lenders, which required stricter protections around disclosures and disputes.The Federal Reserve found in 2024 that users of BNPL services are more likely to rely on high-interest financing tools and are more financially fragile.LendingTree, an online lending marketplace, also found in an April survey that 41% of BNPL users in the US paid late over the last 12 months, up from 34% a year ago.Klarna's latest Q1 results also show that an increasing number of people may not have been paying their loans. While revenue grew 13% year over year and it reached 100 million active users, Klarna also doubled its net losses from million in Q1 2024 to million in Q1 2025 — a 110% increase.During the May 19 earnings call, Klarna attributed the spike in losses to several one-off costs related to depreciation, share-based payments, and restructuring.Klarna's consumer credit losses have also jumped, which its Q1 financial report said is "driven by the accelerated expansion of Pay Later and Fair Financing products." Klarna's first quarter saw a 17% year-on-year increase in credit losses from million to million.Klarna did not immediately respond to requests for comment. #klarna039s #ceo #leans #into #his
    Klarna's CEO leans into his company's image, using an AI doppelganger to deliver earnings highlights
    www.businessinsider.com
    Klarna said it used an AI doppelganger of CEO Sebastian Siemiatkowski to report its updated quarterly earnings. Klarna 2025-05-22T02:31:59Z Save Saved Read in app This story is available exclusively to Business Insider subscribers. Become an Insider and start reading now. Have an account? Klarna said it used an AI avatar of its CEO to report quarterly earnings in a YouTube video. Klarna brands itself as an AI company and has "streamlined" its workforce by 40% since 2022. Klarna's Q1 results show revenue growth but see a spike in net and credit losses. Buy now, pay later services company Klarna said it used an AI doppelganger of CEO Sebastian Siemiatkowski to report its quarterly earnings on Monday.The AI avatar appeared in a video on Klarna's official YouTube channel to deliver earnings highlights. It wore a brown jacket reminiscent of one in Siemiatkowski's corporate headshots, and aside from a lack of blinking and suspect"Our AI-first strategy is driving exceptional returns, we're outpacing competitors, our merchant network is scaling rapidly, and our next-gen products are reshaping money management for millions," a presumably human Siemiatkowski said in a press release.The move comes as Klarna, which last month put its IPO on ice due to economic uncertainty, tries to brand itself as an AI company. In the earnings press release, Klarna said it has "streamlined" its workforce by around 40% since 2022.In 2022, 800 employees were fired, while some were quietly offered an exit package last year after being placed into a "talent pool." In February 2024, Klarna announced that itsKlarna has recently ramped up partnerships with platforms like Walmart, eBay, and DoorDash, but consumer watchdogs have long been concerned about the potential for overspending under BNPL services. Under the Biden administration, theBNPL providers as credit card lenders, which required stricter protections around disclosures and disputes.The Federal Reserve found in 2024 that users of BNPL services are more likely to rely on high-interest financing tools and are more financially fragile.LendingTree, an online lending marketplace, also found in an April survey that 41% of BNPL users in the US paid late over the last 12 months, up from 34% a year ago.Klarna's latest Q1 results also show that an increasing number of people may not have been paying their loans. While revenue grew 13% year over year and it reached 100 million active users, Klarna also doubled its net losses from $47 million in Q1 2024 to $99 million in Q1 2025 — a 110% increase.During the May 19 earnings call, Klarna attributed the spike in losses to several one-off costs related to depreciation, share-based payments, and restructuring.Klarna's consumer credit losses have also jumped, which its Q1 financial report said is "driven by the accelerated expansion of Pay Later and Fair Financing products." Klarna's first quarter saw a 17% year-on-year increase in credit losses from $117 million to $136 million.Klarna did not immediately respond to requests for comment.
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  • Games Inbox: Would you buy a PlayStation that was a PC?

    Should Sony embrace a PC future?The Thursday letters page is surprised that Nintendo Switch 2 stock is relatively easy to find, as one reader looks forward to Hellblade 2 on PS5.
    To join in with the discussions yourself email gamecentral@metro.co.uk
    Box it up
    Hearing about the rumours of the next gen Xbox being basically an ordinary PC makes perfect sense and is not a surprise to me. I think it’s the only logical move left for Xbox, even if I’m not sure how they’re going to make any money from it if Steam and the other stores are going to be on there.PC gaming is quickly taking over, so my question is whether the PlayStation 6 could also be a ‘PC in a box’. It may sound crazy but a few years ago, so too would the idea of Sony games appearing on PC. I really don’t see what the argument would be against it, especially given how expensive the PS5 Pro already is.
    Making the next PlayStation, or at least the PlayStation 7, a PC means Sony don’t have to spend nearly as much on hardware R&D and can instead concentrate on making games. Something that they don’t seem to have had the time or money for this gen.
    I think especially as streaming starts to take off, as the preferred casual method for playing games, it will only be the PC that is left as an alternative. It’s sad in a way but, personally speaking, as long as the games are still good I don’t really care that much.Purple Ranger
    Doomed highlight
    I’ve just beaten Doom: The Dark Ages and thoroughly enjoyed it. I think your review was accurate but since I was playing it for free on Game Pass the faults didn’t really bother me. However, I have to comment on the story, or rather the fact that Bethesda chose to highlight as one of the most important new features of the game.It’s a complete non-event: boring and cliched, with no characters of any interest. Even the game seems to lose interest because there are very few proper cut scenes in the second half, not that that’s a problem. None of it is a problem, really, because who wants a story in a game like Doom? So why did Bethesda make so much of a fuss about it?
    If it had been good that would’ve been one thing. If there’d been a lot of cut scenes that would’ve been something else. But it was just nothing. I really don’t understand why they ever thought to mention it.James
    Speed of Mercury
    Is there a chance you will review Blades Of Fire, please? I’m very interested in MercurySteam games; I love both of their Metroid games and I’m that one person that liked all three of their Castlevania games.Your reviews are the ones I trust the most so if you do have the time I’d appreciate it, the few I’ve seen have been quite mixed.
    Thank you, keep up the excellent work.BeastiebatCurrently playing: Devil May Cry 3: Special Edition, Metroid Dread, and Elevator Action -Returns- S-TributeGC: Thank you. We’re trying to get it done but we’re a bit behind this week, due to staff holidays and press events.
    Email your comments to: gamecentral@metro.co.uk
    News update
    There’s a couple of things I’ve not seen yourselves or any readers mention lately, so I thought I should bring them up.The Sea Of Stars DLC is out now!
    It’s absolutely free too, which seems crazy because it looks quite substantial. I’m looking forward to playing it this weekend when I have more time.
    Another thing I’ve not seen mentioned is that Hogwarts Legacy on Switch 2 can be bought at a huge discount if you own the game on Switch. Around £10 reportedly.
    You can even buy the game on Switch in the sale now and then buy the Switch 2 version, costing under £30 in total, it seems, which is a great deal.
    It’s not an upgrade as the Switch 2 game isn’t a port.
    Keep up the great work! I don’t write in much, but I still read every morning. I finally prefer this than the Teletext days now.Fatys Henrys
    GC: Thank you for your patronage.
    Old and new
    Excited to hear some actual news about the Cyberpunk 2077 sequel and that it will feature at least one whole new city. However, I hope that the game features both the whole of Night City and the new one. Strangely, I can’t think of any sequels that do that. With GTA, they don’t include the previous game and the new one, and I’m not sure anywhere else does either.Weirdly, the only example I can think of that did that is Pokémon Gold and Silver, which had the whole of the map from Red and Blue. I’m sure there’s technical reasons it doesn’t happen usually but while the PlayStation 5 and beyond may no longer show much of a graphical improvement perhaps there’ll be able to do things like this more easily.Kankor
    The end of the beginning
    So, after being reminded that my mother’s partner doesn’t like me very much I’ve cheered up with two lovely pieces of news. Stellar Blade is getting a sequel, very soon. It releases on PC next month. The second announcement is Senua’s Saga: Hellblade 2 on PlayStation 5 in the summer. This is something I was highly anticipating. Just the graphics alone makes it worth the time. So, after this and Gears Of War also releasing on PlayStation I’m not asking if Xbox is truly dead. It’s a fact that Xbox is indeed only kept afloat by Game Pass.This is only the start. Halo will release on PlayStation 5. Fable. Avowed. State Of Decay 3. Starfield. The list goes on. In hindsight this is deserved. Because of the Xbox One’s failure Microsoft lagged behind an entire generation and Sony raced ahead, never looking back. I never brought an Xbox One, actually. The PlayStation 4 was my choice in 2013 and after picking up the last one, at Argos in 2014. I never gave the Xbox One a second look.
    Today, Microsoft are still suffering from their malignant decisions and it is thoroughly deserved. If I was Phil Spencer I’d cancel the upcoming handheld, because that is leading up to a fail, much more so than the Xbox One. Not even ASUS can save Xbox.Shahzaib Sadiq
    Direct from the source
    I’m always fascinated by Nintendo’s Ask the Developers interviews, they’re so in-depth and genuine and I don’t think they get enough recognition. Nintendo’s reputation is of being secretive and distant, but Sony and Microsoft would never do something like this. They just have carefully worded developer quotes that were probably written by a marketing person anyway.Who would’ve guessed they’ve been planning Mario Kart World for eight years or that they were already making Switch 2 games, based on preliminary specs, in 2020? I guess that’s the sort of time you need but it’s very interesting to get exact dates and to hear it from the horse’s mouth.Onibee
    In stock now
    I’ve managed to bag myself a Switch 2 pre-order after you put your article up on where to buy it. I was going to hold off; eventually decided I can’t resist the temptation to play the new Mario Kart. But I think it will be a good long term investment and there’s no ruling out that there might be an eventual price increase of the unit, like there’s been recently with other consoles.After I managed to get my pre-order done about a week ago or so I’ve visited some of those retailers, websites just to see how lucky I got managing to pre-order it in the first place. I’ve been able to see deals every time; different deals but there’s always been at least one available with Mario Kart or the Zelda pack or camera or SD card bundle. I’ve checked out of curiosity about four or five times and could have dropped on a pre-order again and again, so does that mean Nintendo is actually beating the scalpers? Or is it too expensive or is there a lack of interest?
    I couldn’t for the life of me get an Xbox Series X day one, at the start of the generation because of the use of online bots, but it seems something has changed for the better with the latest Nintendo console release. That’s got to be a good thing for everyone, except the scalpers.Nick The Greek
    GC: It’s hard to tell but there’s no indication of a lack of demand, given analysts think Nintendo is being too cautious in its sales predictions. They always said they wanted no shortages at launch, so we guess their plan worked. It was probably helped by the fact that the Xbox Series X/S and PlayStation 5 came out at the same time, during Covid, and so were competing for manufacturing time and resources. By contrast, Switch 2 has a clear run at a quiet time of year for games.
    Inbox also-rans
    I had literally no idea that Fortnite wasn’t on mobile for the last five years. I would’ve figured that was its biggest format, but I guess you’re saying it wasn’t?MouseGC: No, it’s one of the smallest. Apparently not even Fortnite fans want to play with touchscreen controls.
    I would never, ever in a million years pay £80 for a video game. Even if I got it for cheap later, the fact that it was at one point that much would still put me off.Gribbly

    More Trending

    Email your comments to: gamecentral@metro.co.uk
    The small printNew Inbox updates appear every weekday morning, with special Hot Topic Inboxes at the weekend. Readers’ letters are used on merit and may be edited for length and content.
    You can also submit your own 500 to 600-word Reader’s Feature at any time via email or our Submit Stuff page, which if used will be shown in the next available weekend slot.
    You can also leave your comments below and don’t forget to follow us on Twitter.
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    Games Inbox: Would you buy a PlayStation that was a PC?
    Should Sony embrace a PC future?The Thursday letters page is surprised that Nintendo Switch 2 stock is relatively easy to find, as one reader looks forward to Hellblade 2 on PS5. To join in with the discussions yourself email gamecentral@metro.co.uk Box it up Hearing about the rumours of the next gen Xbox being basically an ordinary PC makes perfect sense and is not a surprise to me. I think it’s the only logical move left for Xbox, even if I’m not sure how they’re going to make any money from it if Steam and the other stores are going to be on there.PC gaming is quickly taking over, so my question is whether the PlayStation 6 could also be a ‘PC in a box’. It may sound crazy but a few years ago, so too would the idea of Sony games appearing on PC. I really don’t see what the argument would be against it, especially given how expensive the PS5 Pro already is. Making the next PlayStation, or at least the PlayStation 7, a PC means Sony don’t have to spend nearly as much on hardware R&D and can instead concentrate on making games. Something that they don’t seem to have had the time or money for this gen. I think especially as streaming starts to take off, as the preferred casual method for playing games, it will only be the PC that is left as an alternative. It’s sad in a way but, personally speaking, as long as the games are still good I don’t really care that much.Purple Ranger Doomed highlight I’ve just beaten Doom: The Dark Ages and thoroughly enjoyed it. I think your review was accurate but since I was playing it for free on Game Pass the faults didn’t really bother me. However, I have to comment on the story, or rather the fact that Bethesda chose to highlight as one of the most important new features of the game.It’s a complete non-event: boring and cliched, with no characters of any interest. Even the game seems to lose interest because there are very few proper cut scenes in the second half, not that that’s a problem. None of it is a problem, really, because who wants a story in a game like Doom? So why did Bethesda make so much of a fuss about it? If it had been good that would’ve been one thing. If there’d been a lot of cut scenes that would’ve been something else. But it was just nothing. I really don’t understand why they ever thought to mention it.James Speed of Mercury Is there a chance you will review Blades Of Fire, please? I’m very interested in MercurySteam games; I love both of their Metroid games and I’m that one person that liked all three of their Castlevania games.Your reviews are the ones I trust the most so if you do have the time I’d appreciate it, the few I’ve seen have been quite mixed. Thank you, keep up the excellent work.BeastiebatCurrently playing: Devil May Cry 3: Special Edition, Metroid Dread, and Elevator Action -Returns- S-TributeGC: Thank you. We’re trying to get it done but we’re a bit behind this week, due to staff holidays and press events. Email your comments to: gamecentral@metro.co.uk News update There’s a couple of things I’ve not seen yourselves or any readers mention lately, so I thought I should bring them up.The Sea Of Stars DLC is out now! It’s absolutely free too, which seems crazy because it looks quite substantial. I’m looking forward to playing it this weekend when I have more time. Another thing I’ve not seen mentioned is that Hogwarts Legacy on Switch 2 can be bought at a huge discount if you own the game on Switch. Around £10 reportedly. You can even buy the game on Switch in the sale now and then buy the Switch 2 version, costing under £30 in total, it seems, which is a great deal. It’s not an upgrade as the Switch 2 game isn’t a port. Keep up the great work! I don’t write in much, but I still read every morning. I finally prefer this than the Teletext days now.Fatys Henrys GC: Thank you for your patronage. Old and new Excited to hear some actual news about the Cyberpunk 2077 sequel and that it will feature at least one whole new city. However, I hope that the game features both the whole of Night City and the new one. Strangely, I can’t think of any sequels that do that. With GTA, they don’t include the previous game and the new one, and I’m not sure anywhere else does either.Weirdly, the only example I can think of that did that is Pokémon Gold and Silver, which had the whole of the map from Red and Blue. I’m sure there’s technical reasons it doesn’t happen usually but while the PlayStation 5 and beyond may no longer show much of a graphical improvement perhaps there’ll be able to do things like this more easily.Kankor The end of the beginning So, after being reminded that my mother’s partner doesn’t like me very much I’ve cheered up with two lovely pieces of news. Stellar Blade is getting a sequel, very soon. It releases on PC next month. The second announcement is Senua’s Saga: Hellblade 2 on PlayStation 5 in the summer. This is something I was highly anticipating. Just the graphics alone makes it worth the time. So, after this and Gears Of War also releasing on PlayStation I’m not asking if Xbox is truly dead. It’s a fact that Xbox is indeed only kept afloat by Game Pass.This is only the start. Halo will release on PlayStation 5. Fable. Avowed. State Of Decay 3. Starfield. The list goes on. In hindsight this is deserved. Because of the Xbox One’s failure Microsoft lagged behind an entire generation and Sony raced ahead, never looking back. I never brought an Xbox One, actually. The PlayStation 4 was my choice in 2013 and after picking up the last one, at Argos in 2014. I never gave the Xbox One a second look. Today, Microsoft are still suffering from their malignant decisions and it is thoroughly deserved. If I was Phil Spencer I’d cancel the upcoming handheld, because that is leading up to a fail, much more so than the Xbox One. Not even ASUS can save Xbox.Shahzaib Sadiq Direct from the source I’m always fascinated by Nintendo’s Ask the Developers interviews, they’re so in-depth and genuine and I don’t think they get enough recognition. Nintendo’s reputation is of being secretive and distant, but Sony and Microsoft would never do something like this. They just have carefully worded developer quotes that were probably written by a marketing person anyway.Who would’ve guessed they’ve been planning Mario Kart World for eight years or that they were already making Switch 2 games, based on preliminary specs, in 2020? I guess that’s the sort of time you need but it’s very interesting to get exact dates and to hear it from the horse’s mouth.Onibee In stock now I’ve managed to bag myself a Switch 2 pre-order after you put your article up on where to buy it. I was going to hold off; eventually decided I can’t resist the temptation to play the new Mario Kart. But I think it will be a good long term investment and there’s no ruling out that there might be an eventual price increase of the unit, like there’s been recently with other consoles.After I managed to get my pre-order done about a week ago or so I’ve visited some of those retailers, websites just to see how lucky I got managing to pre-order it in the first place. I’ve been able to see deals every time; different deals but there’s always been at least one available with Mario Kart or the Zelda pack or camera or SD card bundle. I’ve checked out of curiosity about four or five times and could have dropped on a pre-order again and again, so does that mean Nintendo is actually beating the scalpers? Or is it too expensive or is there a lack of interest? I couldn’t for the life of me get an Xbox Series X day one, at the start of the generation because of the use of online bots, but it seems something has changed for the better with the latest Nintendo console release. That’s got to be a good thing for everyone, except the scalpers.Nick The Greek GC: It’s hard to tell but there’s no indication of a lack of demand, given analysts think Nintendo is being too cautious in its sales predictions. They always said they wanted no shortages at launch, so we guess their plan worked. It was probably helped by the fact that the Xbox Series X/S and PlayStation 5 came out at the same time, during Covid, and so were competing for manufacturing time and resources. By contrast, Switch 2 has a clear run at a quiet time of year for games. Inbox also-rans I had literally no idea that Fortnite wasn’t on mobile for the last five years. I would’ve figured that was its biggest format, but I guess you’re saying it wasn’t?MouseGC: No, it’s one of the smallest. Apparently not even Fortnite fans want to play with touchscreen controls. I would never, ever in a million years pay £80 for a video game. Even if I got it for cheap later, the fact that it was at one point that much would still put me off.Gribbly More Trending Email your comments to: gamecentral@metro.co.uk The small printNew Inbox updates appear every weekday morning, with special Hot Topic Inboxes at the weekend. Readers’ letters are used on merit and may be edited for length and content. You can also submit your own 500 to 600-word Reader’s Feature at any time via email or our Submit Stuff page, which if used will be shown in the next available weekend slot. You can also leave your comments below and don’t forget to follow us on Twitter. Arrow MORE: Games Inbox: What is Rockstar Games’ best game? GameCentral Sign up for exclusive analysis, latest releases, and bonus community content. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. Your information will be used in line with our Privacy Policy #games #inbox #would #you #buy
    Games Inbox: Would you buy a PlayStation that was a PC?
    metro.co.uk
    Should Sony embrace a PC future? (Sony/Metro) The Thursday letters page is surprised that Nintendo Switch 2 stock is relatively easy to find, as one reader looks forward to Hellblade 2 on PS5. To join in with the discussions yourself email gamecentral@metro.co.uk Box it up Hearing about the rumours of the next gen Xbox being basically an ordinary PC makes perfect sense and is not a surprise to me. I think it’s the only logical move left for Xbox, even if I’m not sure how they’re going to make any money from it if Steam and the other stores are going to be on there.PC gaming is quickly taking over, so my question is whether the PlayStation 6 could also be a ‘PC in a box’. It may sound crazy but a few years ago, so too would the idea of Sony games appearing on PC. I really don’t see what the argument would be against it, especially given how expensive the PS5 Pro already is. Making the next PlayStation, or at least the PlayStation 7, a PC means Sony don’t have to spend nearly as much on hardware R&D and can instead concentrate on making games. Something that they don’t seem to have had the time or money for this gen. I think especially as streaming starts to take off, as the preferred casual method for playing games, it will only be the PC that is left as an alternative. It’s sad in a way but, personally speaking, as long as the games are still good I don’t really care that much.Purple Ranger Doomed highlight I’ve just beaten Doom: The Dark Ages and thoroughly enjoyed it. I think your review was accurate but since I was playing it for free on Game Pass the faults didn’t really bother me. However, I have to comment on the story, or rather the fact that Bethesda chose to highlight as one of the most important new features of the game.It’s a complete non-event: boring and cliched, with no characters of any interest. Even the game seems to lose interest because there are very few proper cut scenes in the second half, not that that’s a problem. None of it is a problem, really, because who wants a story in a game like Doom? So why did Bethesda make so much of a fuss about it? If it had been good that would’ve been one thing. If there’d been a lot of cut scenes that would’ve been something else. But it was just nothing. I really don’t understand why they ever thought to mention it.James Speed of Mercury Is there a chance you will review Blades Of Fire, please? I’m very interested in MercurySteam games; I love both of their Metroid games and I’m that one person that liked all three of their Castlevania games (yes, Lords Of Shadow 2 was unfocused and padded out, but I loved what it got right so much).Your reviews are the ones I trust the most so if you do have the time I’d appreciate it, the few I’ve seen have been quite mixed. Thank you, keep up the excellent work.Beastiebat (PSN ID) Currently playing: Devil May Cry 3: Special Edition, Metroid Dread, and Elevator Action -Returns- S-TributeGC: Thank you. We’re trying to get it done but we’re a bit behind this week, due to staff holidays and press events. Email your comments to: gamecentral@metro.co.uk News update There’s a couple of things I’ve not seen yourselves or any readers mention lately, so I thought I should bring them up.The Sea Of Stars DLC is out now! It’s absolutely free too, which seems crazy because it looks quite substantial. I’m looking forward to playing it this weekend when I have more time. Another thing I’ve not seen mentioned is that Hogwarts Legacy on Switch 2 can be bought at a huge discount if you own the game on Switch. Around £10 reportedly. You can even buy the game on Switch in the sale now and then buy the Switch 2 version, costing under £30 in total, it seems, which is a great deal. It’s not an upgrade as the Switch 2 game isn’t a port. Keep up the great work! I don’t write in much, but I still read every morning. I finally prefer this than the Teletext days now.Fatys Henrys GC: Thank you for your patronage. Old and new Excited to hear some actual news about the Cyberpunk 2077 sequel and that it will feature at least one whole new city. However, I hope that the game features both the whole of Night City and the new one. Strangely, I can’t think of any sequels that do that. With GTA, they don’t include the previous game and the new one, and I’m not sure anywhere else does either.Weirdly, the only example I can think of that did that is Pokémon Gold and Silver, which had the whole of the map from Red and Blue (thanks to no less than Satoru Iwata himself). I’m sure there’s technical reasons it doesn’t happen usually but while the PlayStation 5 and beyond may no longer show much of a graphical improvement perhaps there’ll be able to do things like this more easily.Kankor The end of the beginning So, after being reminded that my mother’s partner doesn’t like me very much I’ve cheered up with two lovely pieces of news. Stellar Blade is getting a sequel, very soon. It releases on PC next month. The second announcement is Senua’s Saga: Hellblade 2 on PlayStation 5 in the summer. This is something I was highly anticipating. Just the graphics alone makes it worth the time. So, after this and Gears Of War also releasing on PlayStation I’m not asking if Xbox is truly dead. It’s a fact that Xbox is indeed only kept afloat by Game Pass.This is only the start. Halo will release on PlayStation 5. Fable. Avowed. State Of Decay 3. Starfield. The list goes on. In hindsight this is deserved. Because of the Xbox One’s failure Microsoft lagged behind an entire generation and Sony raced ahead, never looking back. I never brought an Xbox One, actually. The PlayStation 4 was my choice in 2013 and after picking up the last one, at Argos in 2014. I never gave the Xbox One a second look. Today, Microsoft are still suffering from their malignant decisions and it is thoroughly deserved. If I was Phil Spencer I’d cancel the upcoming handheld, because that is leading up to a fail, much more so than the Xbox One. Not even ASUS can save Xbox.Shahzaib Sadiq Direct from the source I’m always fascinated by Nintendo’s Ask the Developers interviews, they’re so in-depth and genuine and I don’t think they get enough recognition. Nintendo’s reputation is of being secretive and distant, but Sony and Microsoft would never do something like this. They just have carefully worded developer quotes that were probably written by a marketing person anyway.Who would’ve guessed they’ve been planning Mario Kart World for eight years or that they were already making Switch 2 games, based on preliminary specs, in 2020? I guess that’s the sort of time you need but it’s very interesting to get exact dates and to hear it from the horse’s mouth.Onibee In stock now I’ve managed to bag myself a Switch 2 pre-order after you put your article up on where to buy it. I was going to hold off; eventually decided I can’t resist the temptation to play the new Mario Kart. But I think it will be a good long term investment and there’s no ruling out that there might be an eventual price increase of the unit, like there’s been recently with other consoles.After I managed to get my pre-order done about a week ago or so I’ve visited some of those retailers, websites just to see how lucky I got managing to pre-order it in the first place. I’ve been able to see deals every time; different deals but there’s always been at least one available with Mario Kart or the Zelda pack or camera or SD card bundle. I’ve checked out of curiosity about four or five times and could have dropped on a pre-order again and again, so does that mean Nintendo is actually beating the scalpers? Or is it too expensive or is there a lack of interest? I couldn’t for the life of me get an Xbox Series X day one, at the start of the generation because of the use of online bots, but it seems something has changed for the better with the latest Nintendo console release. That’s got to be a good thing for everyone, except the scalpers.Nick The Greek GC: It’s hard to tell but there’s no indication of a lack of demand, given analysts think Nintendo is being too cautious in its sales predictions. They always said they wanted no shortages at launch, so we guess their plan worked. It was probably helped by the fact that the Xbox Series X/S and PlayStation 5 came out at the same time, during Covid, and so were competing for manufacturing time and resources. By contrast, Switch 2 has a clear run at a quiet time of year for games. Inbox also-rans I had literally no idea that Fortnite wasn’t on mobile for the last five years. I would’ve figured that was its biggest format, but I guess you’re saying it wasn’t?MouseGC: No, it’s one of the smallest. Apparently not even Fortnite fans want to play with touchscreen controls. I would never, ever in a million years pay £80 for a video game. Even if I got it for cheap later, the fact that it was at one point that much would still put me off.Gribbly More Trending Email your comments to: gamecentral@metro.co.uk The small printNew Inbox updates appear every weekday morning, with special Hot Topic Inboxes at the weekend. Readers’ letters are used on merit and may be edited for length and content. You can also submit your own 500 to 600-word Reader’s Feature at any time via email or our Submit Stuff page, which if used will be shown in the next available weekend slot. You can also leave your comments below and don’t forget to follow us on Twitter. Arrow MORE: Games Inbox: What is Rockstar Games’ best game? GameCentral Sign up for exclusive analysis, latest releases, and bonus community content. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. Your information will be used in line with our Privacy Policy
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  • Southwest Airlines Will Require Passengers to Keep Portable Chargers Out During Flights

    Southwest Airlines announced it will require all portable device chargers to be kept in plain sight during all flights while they’re in use. The new policy comes after a number of lithium-ion batteries fires on flights worldwide in recent years. The new policy will start May 28 and will require all Southwest passengers to make sure they don’t have any portable chargers, including power banks and cell phone battery charging cases, in overhead bins or even just inside a bag in under the seat in front of them, while they’re in use. “Using portable charging devices while stored in a bag or overhead bin will no longer be permitted,” the airline told Gizmodo in an emailed statement. “Nothing is more important to Southwest than the Safety of its Customers and Employees.”

    The airline told Gizmodo that it’s okay to keep your portable charger in your carry-on bag if it’s not connected to anything else. But any charger in active use, including one that may be connected to the phone in the form of a case, should be kept visible for the entire flight. The TSA already bans rechargeable and non-rechargeable lithium batteries for phones and laptops from checked baggage. Carry-on baggage is fine, but Southwest Airlines will soon require those chargers to be outside of all bags and visible while in use during the duration of the flight. It’s unclear if other U.S.-based airlines will follow Southwest’s lead, but other airlines around the world have also been cracking down on lithium-ion batteries in an effort to fight fire hazards. As the Associated Press notes, Singapore Airlines and Thai Airways both already prohibit the use of portable chargers on all flights. And Korean Airlines also bans portable chargers from overhead bins.

    The average U.S. passenger brings four different rechargeable devices with them on a flight, according to the UL Standards & Engagement research group, with the most common devices being smartphones, laptops, wireless headphones, and tablets. The most common incidents were caused by vaping devices, which accounted for 35% of all incidents on flights in 2023, while power banks accounted for 16% of all incidents reported. “Flight crews are trained to recognize and respond to lithium battery fires in the cabin,” the FAA explains on its website. “Passengers should notify flight crew immediately if their lithium battery or device is overheating, expanding, smoking or burning.”

    Indeed. If you see something on fire on your flight, battery or otherwise, please let the flight crew know. That’s just generally a good idea.
    #southwest #airlines #will #require #passengers
    Southwest Airlines Will Require Passengers to Keep Portable Chargers Out During Flights
    Southwest Airlines announced it will require all portable device chargers to be kept in plain sight during all flights while they’re in use. The new policy comes after a number of lithium-ion batteries fires on flights worldwide in recent years. The new policy will start May 28 and will require all Southwest passengers to make sure they don’t have any portable chargers, including power banks and cell phone battery charging cases, in overhead bins or even just inside a bag in under the seat in front of them, while they’re in use. “Using portable charging devices while stored in a bag or overhead bin will no longer be permitted,” the airline told Gizmodo in an emailed statement. “Nothing is more important to Southwest than the Safety of its Customers and Employees.” The airline told Gizmodo that it’s okay to keep your portable charger in your carry-on bag if it’s not connected to anything else. But any charger in active use, including one that may be connected to the phone in the form of a case, should be kept visible for the entire flight. The TSA already bans rechargeable and non-rechargeable lithium batteries for phones and laptops from checked baggage. Carry-on baggage is fine, but Southwest Airlines will soon require those chargers to be outside of all bags and visible while in use during the duration of the flight. It’s unclear if other U.S.-based airlines will follow Southwest’s lead, but other airlines around the world have also been cracking down on lithium-ion batteries in an effort to fight fire hazards. As the Associated Press notes, Singapore Airlines and Thai Airways both already prohibit the use of portable chargers on all flights. And Korean Airlines also bans portable chargers from overhead bins. The average U.S. passenger brings four different rechargeable devices with them on a flight, according to the UL Standards & Engagement research group, with the most common devices being smartphones, laptops, wireless headphones, and tablets. The most common incidents were caused by vaping devices, which accounted for 35% of all incidents on flights in 2023, while power banks accounted for 16% of all incidents reported. “Flight crews are trained to recognize and respond to lithium battery fires in the cabin,” the FAA explains on its website. “Passengers should notify flight crew immediately if their lithium battery or device is overheating, expanding, smoking or burning.” Indeed. If you see something on fire on your flight, battery or otherwise, please let the flight crew know. That’s just generally a good idea. #southwest #airlines #will #require #passengers
    Southwest Airlines Will Require Passengers to Keep Portable Chargers Out During Flights
    gizmodo.com
    Southwest Airlines announced it will require all portable device chargers to be kept in plain sight during all flights while they’re in use. The new policy comes after a number of lithium-ion batteries fires on flights worldwide in recent years. The new policy will start May 28 and will require all Southwest passengers to make sure they don’t have any portable chargers, including power banks and cell phone battery charging cases, in overhead bins or even just inside a bag in under the seat in front of them, while they’re in use. “Using portable charging devices while stored in a bag or overhead bin will no longer be permitted,” the airline told Gizmodo in an emailed statement. “Nothing is more important to Southwest than the Safety of its Customers and Employees.” The airline told Gizmodo that it’s okay to keep your portable charger in your carry-on bag if it’s not connected to anything else. But any charger in active use, including one that may be connected to the phone in the form of a case, should be kept visible for the entire flight. The TSA already bans rechargeable and non-rechargeable lithium batteries for phones and laptops from checked baggage. Carry-on baggage is fine, but Southwest Airlines will soon require those chargers to be outside of all bags and visible while in use during the duration of the flight. It’s unclear if other U.S.-based airlines will follow Southwest’s lead, but other airlines around the world have also been cracking down on lithium-ion batteries in an effort to fight fire hazards. As the Associated Press notes, Singapore Airlines and Thai Airways both already prohibit the use of portable chargers on all flights. And Korean Airlines also bans portable chargers from overhead bins. The average U.S. passenger brings four different rechargeable devices with them on a flight, according to the UL Standards & Engagement research group, with the most common devices being smartphones (82%), laptops (41%), wireless headphones (39%), and tablets (36%). The most common incidents were caused by vaping devices, which accounted for 35% of all incidents on flights in 2023, while power banks accounted for 16% of all incidents reported. “Flight crews are trained to recognize and respond to lithium battery fires in the cabin,” the FAA explains on its website. “Passengers should notify flight crew immediately if their lithium battery or device is overheating, expanding, smoking or burning.” Indeed. If you see something on fire on your flight, battery or otherwise, please let the flight crew know. That’s just generally a good idea.
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  • Creating Splatter Effects in Unreal Engine 5 #shorts

    Learn how to create realistic splatter effects using textures and opacity settings in Unreal Engine 5.4! Perfect for enhancing your game visuals with dynamic effects. Watch now!#UnrealEngine #VFX #GameDevelopment #Niagara #Tutorial
    #creating #splatter #effects #unreal #engine
    Creating Splatter Effects in Unreal Engine 5 #shorts
    Learn how to create realistic splatter effects using textures and opacity settings in Unreal Engine 5.4! Perfect for enhancing your game visuals with dynamic effects. Watch now!#UnrealEngine #VFX #GameDevelopment #Niagara #Tutorial #creating #splatter #effects #unreal #engine
    Creating Splatter Effects in Unreal Engine 5 #shorts
    www.youtube.com
    Learn how to create realistic splatter effects using textures and opacity settings in Unreal Engine 5.4! Perfect for enhancing your game visuals with dynamic effects. Watch now!#UnrealEngine #VFX #GameDevelopment #Niagara #Tutorial
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  • Never Before Seen Bacterium in Space Station Could be a Strain Only Found in Space

    In May 2023, Chinese astronauts swabbed several surfaces of their space station Tiangong, then sent the samples back to Earth for analysis. The results are now in: the sample contained one bacterium never before seen, according to a report in the International Journal of Systemic and Evolutionary Microbiology.New Bacteria in Space Station The samples were taken, according to the paper, to help keep astronauts healthy in subsequent missions. “Understanding the characteristics of microbes during long-term space missions is essential for safeguarding the health of astronauts and maintaining the functionality of spacecraft,” according to the paper.There are multiple plausible explanations for both the bacteria’s presence and novelty. It could have hitch-hiked with the astronauts and remained more or less the same. It could have taken that same route, but mutated and evolved. Or it could be a strain only found in space.Bacteria Similarities and AbilitiesTo get a better picture of the possibilities, it might be best to parse the knowns from the unknowns. First, and perhaps most importantly, it is not completely novel. The bacteria shares enough genetic similaritieswith Niallia circulans for it to be considered the same genus. Therefore, the authors named it Niallia tiangongensis.Its general appearance also doesn’t appear to be completely out of this world. The paper described it as an “aerobic, spore-forming, rod-shaped strain.”It does appear to have some interesting abilities, though. According to the paper, it shows “a unique ability to hydrolyse gelatin.” This means it can break down some compounds and add components of water to them, perhaps as a way to feed themselves in an environment with little available food.Adaptations to SpaceDifferences in two proteins that resemble those in its cousin hint that it has evolved enhanced abilities to protect itself from some conditions specific to space. Those include tools to create a biofilm it could perhaps hide beneath, and the means to repair damage from radiation, among other abilities.Its terrestrial cousin has one concerning ability. It can cause infection — even sepsis. Knowing whether N. tiangongensis can do the same, and if so, at what level, will likely be the subject of further investigation, since such understanding is a key part of the China Space Station Habitation Area Microbiome Programthat led to its collection, return, and analysis.Article SourcesOur writers at Discovermagazine.com use peer-reviewed studies and high-quality sources for our articles, and our editors review for scientific accuracy and editorial standards. Review the sources used below for this article:International Journal of Systemic and Evolutionary Microbiology. Niallia tiangongensis sp. nov., isolated from the China Space Station Before joining Discover Magazine, Paul Smaglik spent over 20 years as a science journalist, specializing in U.S. life science policy and global scientific career issues. He began his career in newspapers, but switched to scientific magazines. His work has appeared in publications including Science News, Science, Nature, and Scientific American.
    #never #before #seen #bacterium #space
    Never Before Seen Bacterium in Space Station Could be a Strain Only Found in Space
    In May 2023, Chinese astronauts swabbed several surfaces of their space station Tiangong, then sent the samples back to Earth for analysis. The results are now in: the sample contained one bacterium never before seen, according to a report in the International Journal of Systemic and Evolutionary Microbiology.New Bacteria in Space Station The samples were taken, according to the paper, to help keep astronauts healthy in subsequent missions. “Understanding the characteristics of microbes during long-term space missions is essential for safeguarding the health of astronauts and maintaining the functionality of spacecraft,” according to the paper.There are multiple plausible explanations for both the bacteria’s presence and novelty. It could have hitch-hiked with the astronauts and remained more or less the same. It could have taken that same route, but mutated and evolved. Or it could be a strain only found in space.Bacteria Similarities and AbilitiesTo get a better picture of the possibilities, it might be best to parse the knowns from the unknowns. First, and perhaps most importantly, it is not completely novel. The bacteria shares enough genetic similaritieswith Niallia circulans for it to be considered the same genus. Therefore, the authors named it Niallia tiangongensis.Its general appearance also doesn’t appear to be completely out of this world. The paper described it as an “aerobic, spore-forming, rod-shaped strain.”It does appear to have some interesting abilities, though. According to the paper, it shows “a unique ability to hydrolyse gelatin.” This means it can break down some compounds and add components of water to them, perhaps as a way to feed themselves in an environment with little available food.Adaptations to SpaceDifferences in two proteins that resemble those in its cousin hint that it has evolved enhanced abilities to protect itself from some conditions specific to space. Those include tools to create a biofilm it could perhaps hide beneath, and the means to repair damage from radiation, among other abilities.Its terrestrial cousin has one concerning ability. It can cause infection — even sepsis. Knowing whether N. tiangongensis can do the same, and if so, at what level, will likely be the subject of further investigation, since such understanding is a key part of the China Space Station Habitation Area Microbiome Programthat led to its collection, return, and analysis.Article SourcesOur writers at Discovermagazine.com use peer-reviewed studies and high-quality sources for our articles, and our editors review for scientific accuracy and editorial standards. Review the sources used below for this article:International Journal of Systemic and Evolutionary Microbiology. Niallia tiangongensis sp. nov., isolated from the China Space Station Before joining Discover Magazine, Paul Smaglik spent over 20 years as a science journalist, specializing in U.S. life science policy and global scientific career issues. He began his career in newspapers, but switched to scientific magazines. His work has appeared in publications including Science News, Science, Nature, and Scientific American. #never #before #seen #bacterium #space
    Never Before Seen Bacterium in Space Station Could be a Strain Only Found in Space
    www.discovermagazine.com
    In May 2023, Chinese astronauts swabbed several surfaces of their space station Tiangong (Mandarin for "Heavenly Place"), then sent the samples back to Earth for analysis. The results are now in: the sample contained one bacterium never before seen, according to a report in the International Journal of Systemic and Evolutionary Microbiology.New Bacteria in Space Station The samples were taken, according to the paper, to help keep astronauts healthy in subsequent missions. “Understanding the characteristics of microbes during long-term space missions is essential for safeguarding the health of astronauts and maintaining the functionality of spacecraft,” according to the paper.There are multiple plausible explanations for both the bacteria’s presence and novelty. It could have hitch-hiked with the astronauts and remained more or less the same (although thousands have been identified, there are potentially billions of unknown bacterium on our planet). It could have taken that same route, but mutated and evolved. Or it could be a strain only found in space.Bacteria Similarities and AbilitiesTo get a better picture of the possibilities, it might be best to parse the knowns from the unknowns. First, and perhaps most importantly, it is not completely novel. The bacteria shares enough genetic similarities (two significant stretches of DNA match or are conserved) with Niallia circulans for it to be considered the same genus. Therefore, the authors named it Niallia tiangongensis.Its general appearance also doesn’t appear to be completely out of this world. The paper described it as an “[…] aerobic, spore-forming, rod-shaped strain.”It does appear to have some interesting abilities, though. According to the paper, it shows “a unique ability to hydrolyse gelatin.” This means it can break down some compounds and add components of water to them, perhaps as a way to feed themselves in an environment with little available food.Adaptations to SpaceDifferences in two proteins that resemble those in its cousin hint that it has evolved enhanced abilities to protect itself from some conditions specific to space. Those include tools to create a biofilm it could perhaps hide beneath, and the means to repair damage from radiation, among other abilities.Its terrestrial cousin has one concerning ability. It can cause infection — even sepsis. Knowing whether N. tiangongensis can do the same, and if so, at what level, will likely be the subject of further investigation, since such understanding is a key part of the China Space Station Habitation Area Microbiome Program (CHAMP) that led to its collection, return, and analysis.Article SourcesOur writers at Discovermagazine.com use peer-reviewed studies and high-quality sources for our articles, and our editors review for scientific accuracy and editorial standards. Review the sources used below for this article:International Journal of Systemic and Evolutionary Microbiology. Niallia tiangongensis sp. nov., isolated from the China Space Station Before joining Discover Magazine, Paul Smaglik spent over 20 years as a science journalist, specializing in U.S. life science policy and global scientific career issues. He began his career in newspapers, but switched to scientific magazines. His work has appeared in publications including Science News, Science, Nature, and Scientific American.
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  • Patterns of DNA modifications provide a ‘barcode’ for cell-lineage tracing

    Nature, Published online: 21 May 2025; doi:10.1038/d41586-025-01561-7Differences in the pattern of a biochemical modification called DNA methylation in blood-generating cells and their progeny can be used to accurately track clones through differentiation. This approach identified biased expansions of blood stem cells giving rise to myeloid-type cells as a characteristic of ageing in mice and humans.
    #patterns #dna #modifications #provide #barcode
    Patterns of DNA modifications provide a ‘barcode’ for cell-lineage tracing
    Nature, Published online: 21 May 2025; doi:10.1038/d41586-025-01561-7Differences in the pattern of a biochemical modification called DNA methylation in blood-generating cells and their progeny can be used to accurately track clones through differentiation. This approach identified biased expansions of blood stem cells giving rise to myeloid-type cells as a characteristic of ageing in mice and humans. #patterns #dna #modifications #provide #barcode
    Patterns of DNA modifications provide a ‘barcode’ for cell-lineage tracing
    www.nature.com
    Nature, Published online: 21 May 2025; doi:10.1038/d41586-025-01561-7Differences in the pattern of a biochemical modification called DNA methylation in blood-generating cells and their progeny can be used to accurately track clones through differentiation. This approach identified biased expansions of blood stem cells giving rise to myeloid-type cells as a characteristic of ageing in mice and humans.
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  • RT AidyBurrows: lots of blender-y stuff naturally. :)

    RT AidyBurrowslots of blender-y stuff naturally. :)Superhive: The Superhive Spring Sale is LIVE!Get the Blender tools you need to get your work done faster... for 25% less.But hurry, this sale ends in 6 days!
    #aidyburrows #lots #blendery #stuff #naturally
    RT AidyBurrows: lots of blender-y stuff naturally. :)
    RT AidyBurrowslots of blender-y stuff naturally. :)Superhive: The Superhive Spring Sale is LIVE!Get the Blender tools you need to get your work done faster... for 25% less.But hurry, this sale ends in 6 days! #aidyburrows #lots #blendery #stuff #naturally
    RT AidyBurrows: lots of blender-y stuff naturally. :)
    x.com
    RT AidyBurrowslots of blender-y stuff naturally. :)Superhive (formerly Blender Market): The Superhive Spring Sale is LIVE!Get the Blender tools you need to get your work done faster... for 25% less.But hurry, this sale ends in 6 days!https://b3d.superhivemarket.com/spring2025x
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  • Every world is yours to remake. #RTXRemix gives modders the power to breathe new life into classic games with full ray tracing, remastered assets, and...

    Every world is yours to remake. #RTXRemix gives modders the power to breathe new life into classic games with full ray tracing, remastered assets, and neural rendering including DLSS 4. Enter the K RTX Remix Mod Contest now. Learn More:
    #every #world #yours #remake #rtxremix
    Every world is yours to remake. #RTXRemix gives modders the power to breathe new life into classic games with full ray tracing, remastered assets, and...
    Every world is yours to remake. #RTXRemix gives modders the power to breathe new life into classic games with full ray tracing, remastered assets, and neural rendering including DLSS 4. Enter the K RTX Remix Mod Contest now. Learn More: #every #world #yours #remake #rtxremix
    Every world is yours to remake. #RTXRemix gives modders the power to breathe new life into classic games with full ray tracing, remastered assets, and...
    x.com
    Every world is yours to remake. #RTXRemix gives modders the power to breathe new life into classic games with full ray tracing, remastered assets, and neural rendering including DLSS 4. Enter the $50K RTX Remix Mod Contest now. Learn More: https://www.nvidia.com/en-us/geforce/news/rtx-remix-mod-contest-portal-with-rtx-dlss-4-multi-frame-gen
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